Jordan University of Science and Technology
Jordan University of Science and Technology
Faculty of Engineering
Biomedical Engineering Department
|Course Catalog |
|3 Credit hours (3 h lectures). Principles of momentum, heat, and mass transfer with applications to medical and biological systems and medical |
|device design. |
|Text Book(s) |
|Title |Basic Transport Phenomena in Biomedical Engineering |
|Author(s) |Ronald L. Fournier |
|Publisher |Taylor and Francis |
|Year |1999 |
|Edition |2nd edition: ISBN 1-56032-708-1 |
|References |
|Books |Introduction to transport phenomena, William Thomson |
| |Class Notes |
|Journals |Biomechanics |
|Software |Mathcad +11 |
|Prerequisites |
|Prerequisites by topic |BME-400 |
|Prerequisites by course |BME-400 |
|Co-requisites by course |- |
|Prerequisite for |- |
|Objectives and Outcomes |
|Objectives |Outcomes |
|Understand the role of diffusion and convection|Understand the basic properties of body fluids: Composition, osmotic pressure, ion pumps…etc. |
|in Biotransport |Understand the basic properties of solute transport in Biological Systems |
| |Gain knowledge of active and passive membrane transport and their energetics in cellular system. |
|Learn the mechanisms of Biotransport |Gain knowledge about the physical and flow properties of blood and its cellular components; The |
|fundamentals of the cardiovascular, pulmonary, |rheology of blood. |
|renal, and ocular applications |Understand the flow equations |
| |Understand the basic principles of blood flow in the capillaries |
|Understand Biotransport Fundamentals of the |Understand the O2 transport in Biological Systems |
|cardiovascular, pulmonary, and renal |Gain knowledge about the drug absorption and modeling approaches |
|applications. | |
|Introducing concepts linking transport to |Understand the function of various extracorporeal devices: Blood oxygenaters, Hemodialysis, and |
|function in biological systems. |Immobilized Enzyme reactors. |
|Learn the Mathematical techniques for solving |Gain knowledge for solving and modeling different devices using Mathcad and/or Matlab |
|transport problems | |
|Encourage Long Life Learning, foster team work |Write technical report and give oral presentation on team work project |
|and enhance students communication skills | |
Tentative Course Schedule
|Week |Topic |Reading |
|1 |Course Organization and Introduction |Ch 1 |
| |Physical properties of the Body Fluids & Cell Membrane | |
| |Cell Membrane and Ion Pumps ; Ion Transport contd.; Numerical Examples ; | |
| 2-4 |Solute Transport in Biological Systems |Ch 2 |
| |Diffusion; Diffusive transport through heterogeneous media. Transport via | |
| |Membranes, Solute transport, Numerical Examples on diffusion and convection; | |
| |Solute transport across the capillaries; Shell balances; Krogh Tissue Cylinder| |
| |model; Solute transport in a vascular bed | |
|5-7 |The Physical and flow properties of Blood |Ch3 |
| |Cellular Components; Rheology; Shear stress and shear rate; The | |
| |Hagan-Poiseuille equation; The Casson Equation; Marginal Zone theory; | |
| |Mechanical Energy Balance – Bernoulli’s Equation. | |
| 7-8 |Oxygen Transport in Biological Systems |Ch4 |
| |Oxygen in Blood; the Huill Equation; Tissue Oxygenation Oxygen transport in | |
| |Bio artificial organs; | |
| | | |
| 9-10 |Pharmacokinetic analysis; |Ch5 |
| |Introduction, Drug clearance and modeling, Model-First order Drug absorption | |
| |and elimination Two-Compartment models | |
| | |Ch6 |
|11-12 |Extracorporeal Devices | |
| |Introduction; Blood Oxygenators; Hemodialysis; | |
| | | |
| | | |
| 13-15 |bio-artificial organs, |Ch8 |
| |Introduction; Immunoisolation; Bioartificial Pancreas; Intravascular devices; | |
| |Micro and Macro encapsulation; Islet Insulin Release Model…etc. | |
|Evaluation |
|Assessment Tool |Expected Due Date |Weight |
|Homework, Project, |One week after homework problems are assigned |10% |
|Quizzes | | |
|First Exam |According to the department schedule |25 % |
|Second Exam |According to the department schedule |25 % |
|Final Exam |According to the University final examination schedule |40 % |
|Teaching & Learning Methods |
|Active learning, where students should be active and involved in the learning process inside the classroom, will be emphasized in the delivery of |
|this course. |
|Different active learning methods/approaches such as: Engaged Learning, Project-Based Learning, Cooperative Learning, Problem-based Learning, |
|Structured Problem-solving, will be used. |
|The teaching method that will be used in this course will be composed of a series of mini lectures interrupted with frequent discussions and |
|brainstorming exercises. PowerPoint presentations will be prepared for the course materials. |
|A typical lecture would start with a short review (~ 5 minutes) using both PowerPoint presentations and the blackboard. This review will also depend |
|on discussions which will gauge the students’ digestion of the previous material. Then, the students would have a lecture on new materials using |
|PowerPoint presentations and blackboard. The lecture presentation will be paused every 15 – 20 minutes with brainstorming questions and discussions |
|that will allow the students to reflect and think in more depth about what they learned in that presentation. Then, some example problems will be |
|presented and discussed with the students to illustrate the appropriate problem solving skills that the students should learn. The lecture will be |
|continued for another 15 – 20 minutes, followed by examples and/or a quiz covering the materials taught in the previous two weeks. |
| |
|Policy |
|Attendance |Class attendance is required and applied according to the university regulations (student’s guide page 43). Data |
| |support the idea that class attendance improves learning. It is very difficult as well as uninspiring for me to help a|
| |student who does not attend lectures. What is created in the classroom cannot be reenacted. |
| |Make-up tests will be done according to the university regulations. Please see student’s guide pages 44-45. |
|Homework |Working homework problems is an essential part of this course and they represent a key opportunity to learn the |
| |subjects discussed. All homework problems assigned during a given week are due at the beginning of class on the second|
| |meeting of the following week unless otherwise stated. Late homework will not be accepted. Failure to turn in this |
| |particular homework on time will result in a grade of 0 (zero) for the homework contribution to your final grade. Team|
| |work is encouraged; however, the work one hands in must represent his/her own effort. Homework solutions will be |
| |discussed in class. There will be no handouts of homework solutions. |
|Project |Abstract |
| |Every group (2-3) must do a Matlab project. Each group must submit a project Abstract on November 15th, 2006. This |
| |Abstract should be at most one page and must include: |
| |Project title |
| |Introduction |
| |References |
| | |
| |REPORT: |
| |The report is due at the project presentations during the final week of classes. The submitted report should include a|
| |list of which student was responsible for each section of the report. |
| | |
| |PRESENTATION AND DEMONSTRATION: |
| |There will be a formal presentation and demonstration for each project. All presentations will be made during the |
| |final week of classes. The presentation should be limited to 10 minutes. |
|Student Conduct |All University regulations apply to this course. In particular, the policies concerning academic dishonesty and |
| |withdrawal from a course apply. Dec 6th is the last day to withdraw. I will sign drop slips without restriction. |
|Contribution of Course to Meeting the Professional Component |
|The course contributes to building the fundamental basic concepts in Biomedical Engineering. |
|ABET Category Content |
|Engineering Science |3.0 Credits |
|Engineering Design | |
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BME-531: Biomedical Transport
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