ME- Engineering Graphics and Drawing
DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE & TECHNOLOGY MURTHAL (SONEPAT) HARYANA
DEPARTMENT OF BIOTECHNOLOGY
SCHEME
OF
STUDIES AND EXAMINATIONS
FOR
MASTER OF TECHNOLOGY (BIOTECHNOLOGY)
(Choice Based Credit Scheme w.e.f. 2018-19)
Proposed (As per AICTE Model Curriculum)
DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE & TECHNOLOGY, MURTHAL (SONEPAT)
SCHEME OF STUDIES & EXAMINATIONS
M. Tech. 1st YEAR (SEMESTER – I) (BIOTECHNOLOGY)
Choice Based Credit Scheme w.e.f. 2018-19
|S. | | | |Teaching Schedule |Marks of |Examination Marks |Total |Credit |Duration |
|No. | |Course No. |Course Title | |Class work| | | |of Exam |
| |Categor| | |L |P |Total | |Theory |Practical |
| |y | | | | | | | | |
PCC: Professional Core Course PSE: Program Specific Elective
ELECTIVE - I:
1. BT521C: BIOCHEMICAL ENGINEERING & BIOTECHNOLOGY
2. BT523C: ANALYTICAL TECHNIQUES IN BIOTECHNOLOGY
3. BT525C: MEDICAL MICROBIOLOGY AND BIOTECHNOLOGY
ELECTIVE - II:
1. BT527C: BIOSEPARATION TECHNOLOGY
2. BT529C: BIOINFORMATICS
3. BT531C: BIONANOTECHNOLOGY
AUDIT COURSE 1:
1. AUD531C: ENGLISH FOR RESEARCH PAPER WRITING
2. AUD533C: DISASTER MANAGEMENT
3. AUD535C: SANSKRIT FOR TECHNICAL KNOWLEDGE
4. AUD537C: VALUE EDUCATION
5. AUD539C: CONSTITUTION OF INDIA
6. AUD541C: PEDAGOGY STUDIES
7. AUD543C: STRESS MANAGEMENT BY YOGA
8. AUD545C: PERSONALITY DEVELOPMENT THROUGH LIFE ENLIGHTENMENT SKILLS
NOTE:
1. The students will be allowed to use non-programmable scientific calculator. However, sharing/ exchange of calculator is prohibited in the examination.
2. Electronic gadgets including cellular phones are not allowed in the examination.
3. The choice of students for any elective shall not be a binding on the department.
DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE & TECHNOLOGY, MURTHAL (SONEPAT)
SCHEME OF STUDIES & EXAMINATIONS
M. Tech. 1st YEAR (SEMESTER – II) (BIOTECHNOLOGY)
Choice Based Credit Scheme w.e.f. 2018-19
|S. | | | |Teaching Schedule |Marks of |Examination Marks |Total |Credit |Duration |
|No. | |Course No.|Course Title | |Class work| | | |of Exam |
| |Category| | |L |P |Total | |Theory |Practical |
PCC: Professional Core Course PSE: Program Specific Elective
ELECTIVE - III:
1. BT522C: MOLECULAR MODELLING & DRUG DESIGNING
2. BT524C: Biotechnology in health care
3. BT526C: BIOENERGY AND BIOCHEMICAL TECHNOLOGY
ELECTIVE - IV:
1. BT528C: Animal CELL CULTURE Technology
2. BT530C: BIODIVERSITY AND BIORESOURCE TECHNOLOGY
3. BT532C: METABOLIC ENGINEERING
AUDIT COURSE 2 (any one, other than that opted in Semester- I):
1. AUD531C: ENGLISH FOR RESEARCH PAPER WRITING
2. AUD533C: DISASTER MANAGEMENT
3. AUD535C: SANSKRIT FOR TECHNICAL KNOWLEDGE
4. AUD537C: VALUE EDUCATION
5. AUD539C: CONSTITUTION OF INDIA
6. AUD541C: PEDAGOGY STUDIES
7. AUD543C: STRESS MANAGEMENT BY YOGA
8. AUD545C: PERSONALITY DEVELOPMENT THROUGH LIFE ENLIGHTENMENT SKILLS
NOTE:
1. The students will be allowed to use non-programmable scientific calculator. However, sharing/ exchange of calculator is prohibited in the examination.
2. Electronic gadgets including cellular phones are not allowed in the examination.
3. The choice of students for any elective shall not be a binding on the department.
DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE & TECHNOLOGY, MURTHAL (SONEPAT)
SCHEME OF STUDIES & EXAMINATIONS
M. Tech. 2nd YEAR (SEMESTER – III) (BIOTECHNOLOGY)
Choice Based Credit Scheme w.e.f. 2018-19
|S. No. | | | |Teaching Schedule |Marks of |Examination Marks |Total |Credit |Duration |
| | |Course No. |Course Title | |Class work| | | |of Exam |
| |Category | | |L |P |Total | |Theory |Practical |
| |
|M. Tech. Semester - I (Biotechnology) |
|L |P |Credits | |Class Work |: |25 Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
COURSE OBJECTIVES:
1. To review and acquaint the students versatile tools and techniques employed in Recombinant DNA Technology and apply their understanding of DNA to manipulate specific genes to produce desired traits and knowledge of cloning strategies.
2. To allow skills and make students understand the molecular probes and Polymerase Chain Reaction and study innovative and applications of genetic engineering.
UNIT-I: Basic principles of Recombinant DNA Technology: Introduction, gene cloning- basic steps; tools and vehicles of genetic cloning-restriction enzymes, modifying enzymes, ligases, polymerases, linkers and adaptors; cloning vectors (in brief): plasmids, bacteriophages, cosmids and phasmids, artificial chromosomes as vectors.
Cloning, Recombinant Selection and Expression: Cloning strategy, construction of genomic and cDNA library, integration of DNA insert into the vector, introduction of the rDNA into host cells; recombinant selection and screening methods: genetic, immunochemical, nucleic acid hybridization, HRT and HART; expression strategies: principles in maximizing gene expression, expression in bacteria, yeast and mammalian cells.
UNIT-II: Gene Transfer to Animal and Plant Cells: Direct gene transfer methods, Agrobacterium mediated transfer, plant and animal viruses as vector systems, transgene expression, genetic manipulation of animals, animal cloning-a brief account.
Gene Targeting and Gene Inactivation: Gene targeting in animals and plants, targeted gene replacement, gene inactivation, gene silencing, antisense RNA technology.
UNIT-III: Molecular probes, PCR and hybridization techniques: DNA and RNA as probes, labeling (radioactive vs non-radioactive) and uses of probes, PCR: history and principle, modified PCR (inverse PCR, anchored PCR, PCR for mutagenesis, RT-PCR, asymmetric PCR), cloning of PCR products, hybridization techniques (Southern, Northern, and Western).
UNIT-IV: Applications of Genetic Engineering: Applications in research- in studying gene location, structure, expression and function, in studying regulation of gene expression; applications in producing industrially important molecules, improving agronomic traits by genetic modifications; using genetic modifications to study, prevent and cure diseases, applications in forensic science- DNA profiling and DNA fingerprinting.
COURSE OUTCOMES:
After successful completion of this course students are expected to be able to:
1. To know the scope of Recombinant DNA Technology, techniques used for manipulation of the genetic
material and to gain knowledge on applications of Genetic engineering in microbial, plant and animal
world.
TEXT/ REFERENCE BOOKS:
1. Primrose, S.B., and Twyman, R.M. Principles of Gene Manipulation and Genomics. 7th Edition, Blackwell Publishing (2001).
2. Old, R.W. and Primrose, S.B. Principles of Gene Manipulation- an introduction to genetic engineering. Blackwell Publishing.
3. Sambrook, J. and Russel, D.W. Molecular Cloning: A Laboratory Manual, Vols 1-3, CSHL. (2001).
4. Brown T.A. Genomes., 3rd ed. Garland Science. (2006).
5. Selected papers from scientific journals.
Note:In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five questions in all, selecting at least one from each unit. All questions will carry equal marks.
|BT503C PROTEIN ENGINEERING AND ENZYME TECHNOLOGY |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVE: |
|To introduce students about structural and functional relationships in proteins and altering their structure in order to function ‘better’. |
|To provide basic knowledge of enzyme technology and use of enzymes as tools in industry, agriculture and medicine. |
|UNIT-I: Protein structure and function: Introduction to protein engineering; salient features of amino acids and their |
|R groups; conformation of proteins, the Ramachandran plot, folding, tertiary structure and structural |
|domains and motifs of proteins. prediction of protein structure and conformation from sequence data, |
|relationship between structure and function. |
|Protein Engineering and Design: Methods in protein engineering and design – physical, computational, |
|biochemical and molecular techniques. |
|UNIT-II: Introduction: Enzymes, classification of enzymes, Mechanisms and specificity of Enzyme Action; Concept of |
|active site and energetics of enzyme substrate complex formation; turnover number; Strategies for Enzyme |
|Production, Isolation and Purification. |
|Enzyme Catalysis: Factors affecting action of enzymes- proximity and orientation, strain and distortion, acid base catalysis and covalent catalysis, mechanism of |
|action of chymotrypsin, ribonuclease, carboxypeptidase and lysozyme. |
|UNIT-III: Enzyme Kinetics: Enzyme kinetics and its importance, methods used for investigating the kinetics of enzyme catalyzed reactions, factors affecting the velocity|
|of enzyme catalysed reaction, Michaelis-Menten equation, Vmax, Km and its significance, Lineweaver Burk plot- its advantages and limitations, Eadie- Hofstee and Hanes |
|plots, enzyme inhibition, types of enzyme inhibitions- competitive, uncompetitive, noncompetitive, mixed type inhibition and determination of Ki, feedback inhibition, |
|Bisubstrate reactions- brief introduction to sequential and ping -pong mechanism with examples. |
|UNIT-IV: Applications of Enzymes and Immobilized Enzymes in: medicine, textile, leather, detergent, paper, bakery, dairy industry, beverage and food processing, |
|clinical applications of enzyme estimation, enzymes as biosensors. |
|COURSE OUTCOMES: |
|Students will be able to: |
|know about domains and motifs in a protein and the basis of their prediction. |
|design different strategies for protein engineering and protein design |
|3. acquire knowledge about enzymes and their applications. |
|4. apply appropriate methods for determination of catalytic parameters and activity of enzymes. |
|TEXT / REFERENCE BOOKS: |
|Nature of Enzymology by RL Foster. |
|A textbook of enzyme biotechnology by Alan Wiseman. |
|Enzymes: Biochemistry, Biotechnology and Clinical Chemistry by Trevor Palmer. |
|4. Advances in Enzymology: V. 47 (Hardcover) by Alton Meister. John Wiley and Sons Inc. |
|5. Concepts in Biotechnology by Balasubramanian D, Bryce CFA, Dharmalingam K, Green J, and Jayaraman R |
|Universities Press (2007). |
|6. Bioinformatics - Methods and Applications by Rastogi SC, Mendiratta N and Rastogi P, , PHI (2006). |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
|BT505C: RECOMBINANT DNA TECHNOLOGY LAB |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|-- |
|4 |
|2 |
| |
|Examination |
|: |
|75Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|1. To illustrate creative use of modern tools and techniques for manipulation and analysis of genomic sequences and to expose students to application of recombinant DNA|
|technology in biotechnological research. |
|2. To make learn students isolation of plasmid and genomic DNA, construction of RE map, and restriction endonuclease profile analysis |
| |
|List of Experiments/ Exercises: |
| |
|Isolation of plasmid and genomic DNA from bacteria. |
|Extraction of eukaryotic genomic DNA followed by agarose gel electrophoresis. |
|Restriction endonuclease profile analysis. |
|Polyacrylamide gel electrophoresis (PAGE) of DNA/ RNA. |
|Restriction endonuclease digestion of vector molecule followed by its dephosphorylation. |
|Construction of recombinant DNA and transformation of bacterial DNA with rDNA. |
|To perform polymerase chain reaction. |
|Cloning of PCR products followed by nucleic acid sequencing. |
|RFLP/ RAPD analysis. |
|Southern hybridization/ Northern hybridization. |
| |
|COURSE OUTCOMES: |
|1. Technical know-how on versatile techniques in recombinant DNA technology lab. |
|2. Proficiency in designing and conducting experiments involving genetic manipulation. |
| |
|TEXT /REFERENCE BOOKS: |
|Kun LY. 2006. Microbial Biotechnology. World Scientific. |
|Sambrook J & Russel DW. 2001. Molecular Cloning: a LaboratoryManual. ColdSpringHarbour Lab. Press. |
|TwymanRM. 2003. Advanced Molecular Biology. Bios Scientific. |
|Specific journals and published references. |
| |
| |
|Note: The students will be required to perform 08 experiments/ exercises from the above list and the other two |
|experiments may be designed by the department based on the theory courses: BT501C (Recombinant DNA Technology). |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|BT507C ENZYME TECHNOLOGY LAB |
| |
|M. Tech. Semester – I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|-- |
|4 |
|2 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|Students will gain an enhanced overall understanding of Enzymology, enzyme assays, and in particular the |
|influence of various physicochemical characteristics upon enzyme activity. |
|Students will learn to plan and execute an enzyme assay. |
| |
|List of Experiments/ Exercises: |
| |
|Assay of enzyme catalysed reaction. |
|To study time course of the reaction catalyzed by alkaline phosphatase. |
|To examine the effect of enzyme concentration on the rate of an enzyme catalyzed reaction. |
|To determine temperature optima for alkaline phosphatase. |
|To examine the effect of pH on activity of alkaline phosphatase. |
|To study the effect of substrate concentration on activity of alkaline phosphatase and determine Km and Vmax of the reaction. |
|Demonstration of enzyme immobilization |
|Partial purification of an enzyme by ammonium sulphate fractionation |
|Concentration of a protein sample by lyophilisation |
|Sub -cellular fractionation of organelles from liver cells/plant tissue |
|COURSE OUTCOMES: |
|1. Students will be able to confidently and competently work with enzyme systems in both Academia and |
|Industry. |
|TEXT /REFERENCE BOOKS: |
| |
|Principles & Techniques of Practical Biochemistry, ed. K. Wilson & J. Walker, 1994, Cambridge University Press, Cambridge. |
|Introductory Practical Biochemistry, ed., S.K. Sawhney & Randhir Singh, 2000, Narosa Publishing House, New Delhi. |
|An introduction to Practical Biochemistry by David T. Plummer (1988), McGraw Hill, Book Company. U.K. |
| |
|Note: The students will be required to perform 08 experiments/ exercises from the above list and the other two experiments may be designed by the department based on |
|the theory courses: BT503C (Protein Engineering and Enzyme Technology). |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|BT509C/ FT509C : RESEARCH METHODOLOGY AND IPR |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|2 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES |
|To understand research problem formulation and analyze research related information. |
|To learn and follow research ethics and understand that today’s world is controlled by Computer, Information Technology, but tomorrow world will be ruled by ideas, |
|concept and creativity. |
|To understand that when IPR would take such important place in growth of individual & nation, it is needless to emphasise the need of information about Intellectual |
|Property Right to be promoted among students in general &Engineering in particular. |
| |
|UNIT-I: Meaning of research problem, Sources of research problem, Criteria Characteristics of a good research problem, Errors in selecting a research problem, Scope and|
|objectives of research problem. Approaches of investigation of solutions for research problem, data collection, analysis, interpretation, Necessary instrumentations, |
|Effective literature studies approaches, analysis Plagiarism, Research ethics. |
| |
|UNIT-II: Effective technical writing, how to write report, Paper Developing a Research Proposal, Format of research proposal, a presentation and assessment by a review |
|committee. |
| |
|UNIT-III: Nature of Intellectual Property: Patents, Designs, Trade and Copyright. Process of Patenting and Development: technological research, innovation, patenting, |
|development. International Scenario: International cooperation on Intellectual Property. Procedure for grants of patents, Patenting under PCT. |
| |
|UNIT-IV: Patent Rights: Scope of Patent Rights. Licensing and transfer of technology. Patent information and databases. Geographical Indications. New Developments in |
|IPR: Administration of Patent System. New developments in IPR; IPR of Biological Systems, Computer Software etc. Traditional knowledge Case Studies, IPR and IITs. |
| |
|COURSE OUTCOME |
|Understand that Research Methodology & IPR protection provide an incentive to inventors for further research work and investment in R & D, which will leads to creation |
|of new and better products, and in turns brings about economic growth and social benefits. |
| |
|TEXT/REFERENCE BOOKS: |
| |
|Stuart Melville and Wayne Goddard, “Research methodology: an introduction for science & engineering students’ |
|Wayne Goddard and Stuart Melville, “Research Methodology: An Introduction” |
|Ranjit Kumar, 2nd Edition, “Research Methodology: A Step by Step Guide for beginners” |
|Halbert, “Resisting Intellectual Property”, Taylor & Francis Ltd. 2007. |
|Mayall , “Industrial Design”, McGraw Hill, 1992. |
|Niebel , “Product Design”, McGraw Hill, 1974. |
|Asimov, “Introduction to Design”, Prentice Hall, 1962. |
|Robert P. Merges, Peter S. Menell, Mark A. Lemley, “ Intellectual Property in New Technological Age”, 2016. |
|T. Ramappa, “Intellectual Property Rights Under WTO”, S. Chand, 2008 |
| |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
|BT521C BIOCHEMICAL REACTION ENGINEERING AND BIOENEERGETICS (Elective I) |
|M. Tech. Semester - I (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|To provide understanding of fundamentals about energy processes taking place in cells, their kinetics with respect to commercial applications. |
|Also to demonstrate concepts and applications of bioenergetics and thermodynamics. |
| |
|UNIT-I: Bioprocess Thermodynamics: Biological systems as open, non- equilibrium systems, activity cofficients and phase equilibrium, thermodynamics concepts for |
|irrerersible biological processes, concept of flux and force. Concepts of entropy production, constitutive equations and coupling of biological processes. |
| |
|UNIT-II: Biochemical Reaction Engineering: Kinetics of homogeneous reactions, reaction mechanism, temperature dependency from Arrhenius Law, Theretical prediction of |
|rate constant, interpretation of batch kinetic data, kinetics of substrate utilization, product formation and biomass production. |
| |
|UNIT-III: Models: Monod growth model and its various modifications, structured and unstructured kinetic rate models, thermal death kinetics of cells and spores, medium |
|and air serialization. Chemical mechanisms of biological energy conversion in mitochondria and chloroplasts. |
| |
|UNIT-IV: Experimental studies and theories photosynthesis energy transfer kinetics, cytochrome C oxide |
|(Cytochsome oxidase oxygen theme) or photosystem II (photosystem II Maganese oxygen; bacteriorhodopsin proton pumping) DNA base recognition and replication fidelity, |
|Gibbs free energy, protein folding and stability, Ligand binding, protein- protein and protein DNA interactions, osmosis, dialysis and donnau effect. |
| |
|COURSE OUTCOMES: |
|Students should be able to understand basic biochemical reactions and there engineering, dynamics and conversion for exploitation as biotechnological tools. |
| |
|TEXT / REFERENCE BOOKS: |
|Principles andpractice cell and tissue reaction engineering- Regine Eibl, Dieter Eible, Raif partner, G.Catapano and peter Czemak- Springer. |
|Introduction to biochemical engineering- DG Rao Tata McGraw Hill |
|Introduction to chemical Engineering Thermodynamics- JM Smith, HC Van Ness, MM Abbott and B Bhatt Mc Graw Hill Physical Biochemistry ed. Van Holde |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five questions|
|in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
| |
| |
| |
| |
|BT 523C ANALYTICAL TECHNIQUES IN BIOTECHNOLOGY (Elective I) |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To develop the skills to understand the theory and practice of bio analytical techniques. |
|To provide scientific understanding of analytical techniques and detail interpretation of results. |
| |
|UNIT-I: Cellular Imaging Techniques: Microscopy- Light, electron (scanning & transmission), phase contrast, fluorescence microscopy, phase contrast, fluorescence, |
|atomic force microscopy. |
|Centrifugation: Principle of centrifugation, basic rules of sedimentation, sedimentation coefficient, various types of centrifuges, different types of rotors, |
|differential centrifugation, density gradient centrifugation (Rate zonal and Isopycnic). |
| |
|UNIT-II: Applications of spectroscopy to the study of biomolecules: UV-Vis spectroscopy, circular dichroism, fluorescence, NMR, mass, IR and Raman spectroscopy, X-Ray |
|diffraction. |
| |
|UNIT-III: Biophysical techniques to purify and study proteins: Dialysis, isoelectric precipitation, salting out and precipitaion by inorganic solvents, ion exchange, |
|gel filtration, reverse phase, affinity chromatography, Gas chromatography and HPLC. |
|Analysis of Proteins: Electrophoretic separation of proteins (single dimension native and denaturing gels, 2D and digital electrophoretic analysis), detection |
|(staining, blotting and immuno-detection, ELISA, RIA) and purification of proteins by various chromatography, HPLC, immunoprecipitation. |
| |
|UNIT-IV: High resolution separation for value added biotechnological products: Difficulties with traditional methodologies;, MF/UF/NF for high resolution separation. |
|Radioactivity: Radioactive & stable isotopes, Pattern and rate of radioactive decay, Units of radioactivity. Measurement of radioactivity: Geiger-Muller counter, solid |
|& liquid scintillation counters; Autoradiography. Applications of isotopes in research. |
| |
|COURSE OUTCOMES: |
|To be able to use selected analytical techniques. |
|To understand the strengths, limitations and creative use of techniques for problem-solving. |
| |
|TEXT / REFERENCE BOOKS: |
|Campbell and Durek, Biological Spectroscopy. |
|D.Friefelder, Freeman W.H. Physical Biochemistry, 2nd edition, U.S.A. |
|Robert. D. Braun. Introduction to instrumental analysis. McGraw Hill International Edition, Chemistry Series. (1987). |
|Kenkel J. Analytical Chemistry for technicians. Lewis Publishers. Boca Raton. (1994). |
|Wilson K. and Walker J. Principles and techniques of Practical Biochemistry. Cambridge University Press, Cambridge. (1994). |
|Upadhyay A. Upadhyay K. and Nath N. Biophysical Chemistry: Principle and Techniques, 2nd edition. Himalaya Publication House.Delhi. (1998). |
|Vanholde K. E. Physical Biochemistry, 2nd edition. Prentice Hall Inc., New Jersey. (1985). |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
|BT525C MEDICAL MICROBIOLOGY AND BIOTECHNOLOGY (Elective I) |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
| |
| |
|COURSE OBJECTIVES: |
|To ensures the students to understand about the microbiology and diseases |
|This advanced course aims to extend your understanding and appreciation of interactions between microorganisms and parasites; antimicrobial agents and microbial |
|resistance; characteristics of viruses, medically-important fungi, pathogenesis and diagnosis of viral infections; infections of the skin and respiratory tract. |
|To understand the mechanism of immune system. |
| |
|UNIT-I: Introduction: Microbial Diseases, Primary and opportunistic pathogens, Host- Parasite Relationship, Infection Types , Nosocomial Infections, Modes of Disease |
|Transmission, Determinants of Virulence, Anti-phagocytic factors, Endotoxins and Exotoxins, Types of Infectious Disease – Localised , Generalized, Septicaemia, Pyaemia.|
|Endemics, Epidemics and Pandemics. |
|UNIT-II: Immune Mechanisms: Immunity- Types, Antigens, Antibody. Innate immune Response, Humoral Immune Response[Primary and Secondary], Cell Mediated Immune Response- |
|Mechanism of killing of foreign Molecules by Cytotoxicity, Cell mediated killing by natural killer Cells, Antibody dependent cell mediated cytotoxicity, Delayed |
|Hypersenstivity. |
|UNIT-III: Microbial Disease: Detailed account of medically importantBacterial [ Mycobacteria,Spirochates], Viral[ |
|HIV and Influenza virus] and fungal pathogens[ Aspergillus,Coccidiodes]. Their modes of transmission , |
|pathogenesis, diagnosis and treatment modalities. |
|UNIT-IV: Diagnostic and Therapeutics: Clinical Samples-Types, Methods of Collection and storage. Disease |
|Diagnosis by MicroscopicObservations and Culture Methods. Serological tests, Molecular Diagnosis, |
|Bacteriophage Typing etc. Therapeutics: Antibacterial, Antifungal and Antiviral chemotherapy , Drug |
|resistance, Vaccines , Gene Therapy , antisense Therapy. |
|COURSE OUTCOMES: |
|Demonstrate an awareness of the global burden of infectious diseases and understand its impact on world health and future implications for under-developed |
|countries . |
|Demonstrate a basic understanding of the pathogenesis of some important infections of humans, and be able to identify the causative agents. |
|Demonstrate an understanding of the importance of the factors that influence vaccine design and development. |
|TEXT/ REFERENCE BOOKS: |
|Ananthanarayanan, R. and Jayaram Panicker C.K. Text of Microbiology, Orient Longman. (1997). |
|Mackie and McCartney, Medical Microbiology Vol.1: Microbial Infection Vol.2: Practical Medical Microbiology Churchill Livingstone. (1996). |
|Shanson D.C., Microbiology in Clinical Practice. Wright PSG. (1982). |
|Baron E.J., Peterson L.R. and Finegold S.M. Mos, Bailey and Scott’s Diagnostic Microbiology. (1990). |
|Jawetz et. al. Medical Microbiology. |
|Davis Harper, Microbiology, Row publisher. |
|Kuby, Immunology Roitt, Brostoff, Male, Immunology. |
| |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
| |
| |
|BT527C BIOSEPARATION TECHNOLOGY (Elective II) |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|The goal of this course is to provide insightful overview of fundamentals of down stream processing for biochemical product recovery, through reading assignments and |
|homework sets. |
|Also to demonstrate new concepts and emerging technologies that are likely to benefit biochemical product recovery in the future. |
|UNIT-I: Introduction to bio products and bioseparations: Range and characteristics of bioproducts, characteristic of fermentation broth, selection of unit operations |
|with due consideration of physical, chemical and biochemical aspects of biomolecules stages of downstream processing, fundamental principles of obtaining products from |
|cell cultures, intracellular vs extracellular product recovery, strategies for biochemical process overview. |
| |
|UNIT-II: Removal of insoluble: Primary separation, removal of insoluble and biomass (and particulate debries) separation techniques, flocculation and sedimentation. |
|Filtration and centrifugation as principal unit operations. Pretreatnent of fermentation broth, filter media and equipment’s, conventional vs cross flow filtration, |
|continuous filtration, filter cake resistance, specific cake resistance, washing and dewatering of filter cakes. Centrifugal separators. |
|. |
|UNIT-III: Isolation of products: Adsorption and solvent extraction as principal operations, liquid- liquid extraction, choice of solvent, single stage operations, |
|multistage cross current operation, multistage cross current operation, multistage counter current operation (with and without reflux). Equipment for liquid- liquid |
|extraction, kinetics and modelling of extraction cycles. Different type of extractors and their designing. Nanoparticle based extraction methodologies. |
|. |
|UNIT-IV: Purification and polishing: Selective techniques for product and removal of impurities of similar chemical functionalities and physical properties. |
|Chromatographies, electrophoresis and precipitations . End use product dictations for final sequence utilization crystallizations and drying, packaging of products and|
|waste water treatment technologies from a bioproduct plant. Case studies. |
|COURSE OUTCOMES: |
|Engineers should be able to draw bio product recovery trains for specific bio products in biotechnology industry. |
|TEXT/ REFERENCE BOOKS: |
|Baily & oils: Biochemical Engg. Academic press |
|H. Gunzler- Handbook of analytical techniques- wiley publications. |
|H.J. Rehm and G. Reed, Biotechnology- Vol. 3, 4,5, Verlag publishers. |
|Humphrey, Aiba and Miller, Biochemcial Engg., Academic press |
|Murray Moo- Young, Comprehensive biotechnology, Vol. II- latest ed. Pergan publishers. |
|Product recovery in Bioprocess technology, Heinemann, Butterworth publication. |
|Stanbury & whitteker, principles of fermentation technology, pergamon press. |
|Westermeier- Electrophoresis in practice, wiley publications. |
|Willared at al.- International Methods of analysis- VBS publications. |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
| |
| |
|BT529C BIOINFORMATICS (Elective II) |
|M. Tech. Semester - I (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|Course aims at providing an elementary knowledge in Bioinformatics and Biological Information on the web. |
|Learn Fundamentals of Databases and Sequence alignment and Understanding of popular bioinformatics database. |
|UNIT–I: Introduction: Introduction to bioinformatics, Sequence Analysis: File formats for bio-molecular sequences- GenBank, FASTA, GCG, MSF etc., sequence similarity, |
|identity and homology, homologues, orthologues, paralogues and xenologues. |
|Scoring Matrices and Database searches: Matrices for nucleic acid and protein sequences, PAM and BLOSUM series; Keyword-based Entrez and SRS, sequence-based- BLAST & |
|FASTA, their use in sequence analysis, on-line use of these tools and interpretation of results from various sequences. |
|UNIT–II: Pairwise and Multiple Sequence Alignments: Needleman and Wunsch, Smith and Waterman algorithms, gap penalties, use of pairwise alignments for analysis of |
|nucleic acid and protein sequences; various approaches for MSA (progressive, hierarchical etc.), CLUSTALW and PileUp algorithm, their application in sequence analysis, |
|dendrograms. |
|Sequence Patterns and Profiles: Sequence patterns, motifs and profiles, pattern representations viz. consensus, regular expression (Prosite-type) and sequence profiles,|
|profile-based database searches using PSI-BLAST, analysis and interpretation of profile-based searches. |
|UNIT–III: Taxonomy and Phylogeny: Basic concepts in systematics, taxonomy and phylogeny, molecular evolution, nature of data used in taxonomy and phylogeny, |
|phylogenetic trees- various types and their construction, mathematical basis for phylogenetics, genetic algorithms, multiple alignment. |
|Phylogenetic Analysis– building the data model, extraction of a phylogenetic data set, tree building methods, distance methods, character based method, phylogenetic |
|software- gene prediction methods, genome analysis and annotation, large–scale genome analysis and computational tools. |
|UNIT–IV: Protein and nucleic acid properties: Computation of parameters using proteomic tools at the ExPASy server, GCG utilities and EMBOSS; secondary structure |
|prediction- algorithms viz. Chou Fasman, GOR methods, Mathew’s correlation coefficient; tertiary structure prediction- methods for 3D structure prediction (sequence |
|similarity/identity of target proteins, protein folding etc.), homology modeling, fold recognition, threading approaches, ab-initio structure prediction methods. |
|Drug Designing: Fundamentals of docking small and macromolecules to proteins and nucleic acids, Bioinformatics in drug designing- drug discovery cycle, physicochemical |
|principles of drug action, lead discovery, lead modification, optimization, docking– docking algorithms, structure based drug design- rational design, pharmacophores, |
|QSAR, ADME/T, drug delivery. |
|COURSE OUTCOMES: |
|Students will understand scope of Bioinformatics and approaches to drug discovery and also learn description and applications of various algorithms, phylogenetic |
|analysis and patterns of alignment.. |
|TEXT / REFERENCE BOOKS: |
|1. Pennington SR, Dunn MJ, “Proteomics from Protein Sequence to Function”, Viva Books Ltd, 2002 |
|2. David W Mount, “Bioinformatics: Sequen |
|3. Leach A.R. , “Molecular Modelling - Principles and Applications”, 2nd Edition, Prentice Hall, 2001. |
|4. Prasad R.K., “Quantum Chemistry”, Halsted Press, 1992. |
|5. Ramachandran K. I., Deepa G., Namboori K., “Computational Chemistry and Molecular Modeling: Principles |
|and Applications”, Springer, 2008. |
|6.Young, D.C., “Computational Chemistry: A Practical Guide for Applying Techniques to Real-World |
|Problems”, Wiley-Interscience, 2001. |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
|BT531C BIONANOTECHNOLOGY (Elective II) |
| |
|M. Tech. Semester - I (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|50 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To learn different approaches for nanomaterial synthesis, including conventional mechanical and chemical synthesis procedures and new age biological synthesis |
|processes. |
|To analyze several techniques aims at characterization of nanomaterials. |
|To analyze the use of nanomaterials for routine biotechnological processes of transfection and cloning for betterment of the society. |
|UNIT-I: Introduction to Nanoscience and Nanotechnology: History of nanoscience and technology; |
|nanomaterials- structural, chemical and physical properties; mechanical, optical and electrical behaviour of |
|nano structures. |
|Nanofabrication and Nanosynthesis: Synthesis techniques- gas phase synthesis, controlled flame synthesis, liquid phase synthesis, mechanical synthesis, other related |
|methods; nanolithography; nanocoating, biological production of nanoparticles- fungi, bacteria, yeast and actinomycetes. |
|UNIT-III: Nanostructures and Nanomaterials: Introduction; fullerenes; carbon nanotubes; quantum nanodots; nanorods; nanocomposites; polymeric nanomaterials; |
|bionanostructures: protein-based nanostructures, DNA-based nanostructures, DNA-protein nanostructures, DNA gold nanoparticle conjugates, DNA-templated electronics. |
|UNIT-III: Instrumentation techniques for Nanotechnology: Low energy electron diffraction (LEED), scanning probe microscopy, SEM, TEM, XRD (Powder/ Single/ Crystal), |
|atomic force microscopy (AFM), scanning tunneling microscopy (STM), various forms of spectroscopy for the analysis of biological systems, nuclear magnetic resonance |
|(NMR). |
|UNIT-IV: Applications of Bionanotechnology: Nanomedicine- therapeutic nanodevices; nanoparticles- for disease diagnosis, for drug solubilization and delivery; |
|nanoparticles as biosensors, biochips; use of nanoparticles- as molecular imaging probes, as non-viral transfection agents; nanoparticles for cleaning environment, |
|particularly heavy metal bioremediation and for enhanced oil-recovery; . |
|COURSE OUTCOMES: |
|Know relevance of using materials of nano-scale with concept clarity for differences posed by the two classes in terms of their behaviour. |
|Able to co-relate interesting properties of nanomaterials with biological entities to devise systems for better and easy detection of molecules or pathogen, control of |
|microorganisms, as future drug delivery agents, and bioremediation of the environment. |
|TEXT / REFERENCE BOOKS: |
|Goodsell, David S. Bionanotechnology- Lessons from Nature. John Wiley & Sons, INC., Publication. (2004). |
|Niemeyer C.M. and Mirkin, C.A. Nanobiotechnology- Concepts, Applications and Prespectives, Wiley-VCH Verlag. (2004). |
|Avouris, P., Klitzing, K. Von, Sakaki, H. and Wiesendanger, R. NanoScience and Technology Series. Springer. (2003). |
|Bauerlein, E. Biomineralization- From Biology to Biotechnology and Medical Applications. Wiley-VCH Verlag. (2000). |
|Bhushan, Bharat. Handbook of Nanotechnology. Springer. (2004). |
|Scherge, M. and Gorb, S.N. Biological Micro- and Nanotribology- Natures solution, Springer. (2003). |
|Lyshevski, Sergey Edward. Nano- and Microscience, Engineering, Technology, and Medicine Series. CRC press. (2001). |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
|AUD531C: ENGLISH FOR RESEARCH PAPER WRITING (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|Students will be able to: |
|Understand that how to improve your writing skills and level of readability, |
|Learn about what to write in each section, |
|Understand the skills needed when writing a Title, and |
|Ensure the good quality of paper at very first-time submission |
|Course Outcomes: |
|The Students will become conscious citizens of India aware of their duties, rights and functions of various bodies of governance and welfare; thereby well equipped to |
|contribute to India. |
| |
| |
|Syllabus contents: |
| |
|UNIT I: Basics of Writing Skills: |
|Subject Verb Agreements; Parallelism; Structuring Paragraphs and Sentences; Being Concise and Removing Redundancy; Avoiding Ambiguity and Vagueness; Dangling Modifiers |
| |
|UNIT II: Reviewing and Citation: |
|Clarifying Who Did What; Highlighting Your Findings from Literature; Hedging and Critiquing; Paraphrasing; Avoiding Plagiarism; Formatting and Citation (Publication |
|Manual of the American Psychological Association) |
| |
|UNIT III: Sections of a Research Paper: |
|Writing Effective and Impressive Abstract; Writing Introduction; Review of Literature; Defining Objectives of the Study; Methodology Adopted; Results Obtained; |
|Discussion and Conclusion; Editing and Proof Reading to Ensure Quality of paper |
| |
|UNIT IV: Oral Presentation for Academic Purposes: |
|Oral Presentation for Seminars, Conferences and Symposiums; Poster Presentation; Choosing Appropriate |
|Medium; Interaction and Persuasion |
| |
|TEXT / REFERENCE BOOKS: |
|Goldbort R (2006) Writing for Science, Yale University Press (available on Google Books). |
|Day R (2006) How to Write and Publish a Scientific Paper, Cambridge University Press. |
|Highman N (1998), Handbook of Writing for the Mathematical Sciences, SIAM. Highman’sbook. |
|Adrian Wallwork, English for Writing Research Papers, Springer, New York Dordrecht Heidelberg London, 2011 |
|Mc Murrey,David A. and Joanne Buckley. Handbook for Technical Writing. New Delhi: Cengage Learning, 2008. |
| |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
| |
|AUD533C: DISASTER MANAGEMENT (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|Learn to demonstrate a critical understanding of key concepts in disaster risk reduction and humanitarian response |
|Critically evaluate disaster risk reduction and humanitarian response policy and practice from multiple perspectives |
|Develop an understanding of standards of humanitarian response and practical relevance in specific types of disasters and conflict situations |
|Critically understand different aspects of disaster management |
|Course Outcomes: |
|A student will be able to: |
|Know the significance of disaster management, |
|Study the occurrences, reasons and mechanism of various types of disaster |
|Learn the preventive measures as Civil Engineer with latest codal provisions |
|Apply the latest technology in mitigation of disasters |
| |
|Syllabus contents: |
| |
|UNIT I: Introduction to Disaster Management: Definitions: Disaster, Emergency, Hazard, Mitigation, Disaster Prevention, Preparedness and Rehabilitation, Risk and |
|Vulnerability, Classification of Disaster, Natural and Man made Disasters, Disaster Management Act 2005, Role of NDMA, NDRF, NIDM |
|Risk and Vulnerability to disaster mitigation and management options: Concept and Elements, Risk Assessment, Vulnerability, Warning and Forecasting. |
| |
|UNIT II: Hydro-meteorological based disasters I: Tropical Cyclones, Floods, droughts, mechanism, Causes, role of Indian Metrological Department, Central Water |
|Commission, structure and their impacts, classifications, vulnerability, Early Warning System, Forecasting, Flood Warning System, Drought Indicators, recurrence and |
|declaration, Structural and Non-structural Measures. |
|Hydro-meteorological based disasters II: Desertification Zones, causes and impacts of desertification, Characteristics, Vulnerability to India and Steps taken to combat|
|desertification, Prevention. |
| |
|UNIT III: Geological based disasters: Earthquake, Reasons, Direct and Indirect Impact of Earthquake; Seismic Zones in India, Factors, Prevention and Preparedness for |
|Earthquake, Tsunamis, Landslides and avalanches: Definition, causes and structure; past lesson learnt and measures taken; their Characteristic features, Impact and |
|prevention, structural and non-structural measures. |
| |
| |
|UNIT IV: Manmade Disasters I: Chemical Industrial hazards; causes and factors, pre- and post disaster measures; control ; Indian Standard Guidelines and Compliance; |
|Oil Slicks and Spills, Outbreak of Disease and Epidemics, Traffic accidents; classification and impact, War and Conflicts; Fire risk assessment; Escape routes; fire |
|fighting equipment; |
|Use of remote sensing and GIS in disaster mitigation and management. |
| |
| |
|TEXT / REFERENCE BOOKS: |
|Thomas D. Schneid., Disaster Management and Preparedness, CRC Publication, USA, 2001 |
|Patrick Leon Abbott, Natural Disasters, Amazon Publications, 2002 |
|Ben Wisner., At Risk: Natural Hazards, People vulnerability and Disaster, Amazon Publications, 2001 |
|Oosterom, Petervan, Zlatanova, Siyka, Fendel, Elfriede M., “Geo-information for Disaster Management”, Springer Publications, 2005 |
|Savindra Singh and Jeetendra Singh, Disaster Management, Pravalika Publications, Allahabad |
|Nidhi GaubaDhawan and AmbrinaSardar Khan, Disaster Management and Preparedness, CBS Publishers & Distribution |
|Selected Resources Published by the National Disaster Management Institute of Home Affairs, Govt. of India, New Delhi. |
| |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including cellular phones are not allowed in the examination. |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|AUD535C: SANSKRIT FOR TECHNICAL KNOWLEDGE (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|To get a working knowledge in illustrious Sanskrit, the scientific language in the world |
|Learning of Sanskrit to improve brain functioning |
|Learning of Sanskrit to develop the logic in Mathematics, Science & other subjects |
|Enhancing the memory power |
|Students will be able to |
| |
|Understand basic Sanskrit language |
| |
|Understand Ancient Sanskrit literature about science and technology |
| |
|Get equipped with Sanskrit and explore the huge knowledge from ancient literature |
| |
| |
|Syllabus contents: |
|[pic] |
| |
|TEXT / REFERENCE BOOKS: |
|“Abhyaspustakam” – Dr.Vishwas, Samskrita-Bharti Publication, New Delhi |
|“Teach Yourself Sanskrit” Prathama Deeksha-VempatiKutumbshastri, Rashtriya Sanskrit Sansthanam, New Delhi Publication |
|“India’s Glorious Scientific Tradition” Suresh Soni, Ocean books (P) Ltd., New Delhi. |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
|AUD537C: VALUE EDUCATION (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|The students will be able to |
|Understand value of education and self- development |
|Imbibe good values in students |
|Let the should know about the importance of character |
|Course Outcomes: |
|The students will be able to |
|1. Knowledge of self-development |
|2. Learn the importance of Human values |
|3. Developing the overall personality |
|4. Strengthen the “EQ” |
| |
| |
|Syllabus contents: |
| |
|Unit I: Hierarchy and Classification of values, Values and Belief Systems, Competence in professional ethics, Value judgment based on cultural, tradition and |
|interdependence. |
| |
|Unit II: Need for value education, Sense of duty.Devotion, Self-reliance. Honesty, Humanity, trust.Patriotism and national Unity. Harmony in the nature and |
|realization of coexistence. Vision of better India |
| |
|Unit III: Understanding the meaning and realizing the effect of the following: |
|Aware of self- destructive habits, Knowledge, Acceptance, Love, Situations, happiness, Bliss, Peace,Power, Purity , Realization, Assertiveness, Regard, Respect, |
|Sensitive, Divinity, emotions, Repentance, hurt, Ego, Attachment, worry, Resentment, Fear, Anxiety, Greed, Criticism, Tension, Frustration, Expectation, Irritation, |
|Anger, Guilt, Jealous, Pear Pressure, True Friendship, Cooperation -Coordination- competition. Enhancing self esteem and personality. |
| |
|Unit IV: Hinduism, Jainism, Buddhism, Christianity, Islam, Sikhism. Self-management and Good health ( Role, Responsibility, Relation, Routine, Requirements, |
|Resources). My True self and Original qualities.Supreme-soul- source of values. What Scientists say about super power? |
| |
|TEXT / REFERENCE BOOKS: |
|Chakroborty, S.K. Values and Ethics for organizations Theory and practice. Oxford University Press, New Delhi. |
|R R Gaur, R Sangal, G P Singh.Human Values and Professional Ethics. Excell Books, New Delhi. |
|Value Education in Spirituality- Course-I, course -II by Brahma Kumaris Education Wing, RajyogaEducation & Research Foundation, Mount Abu, Rajasthan. |
|True Management: I K International Publication 2018. |
| |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
|AUD 539C: CONSTITUTION OF INDIA (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|Students will be able to: |
| |
|Understand the premises informing the twin themes of liberty and freedom from a civil rights perspective. |
| |
|To address the growth of Indian opinion regarding modern Indian intellectuals’ constitutional role and entitlement to civil and economic rights as well as the emergence|
|of nationhood in the early years of Indian nationalism. |
| |
|To address the role of socialism in India after the commencement of the Bolshevik Revolution in 1917 and its impact on the initial drafting of the Indian Constitution. |
|Course Outcomes: |
|The Students will become conscious citizens of India aware of their duties, rights and functions of various bodies of governance and welfare; thereby well equipped to |
|contribute to India. |
| |
| |
|Syllabus contents: |
| |
|Unit I: Making of the Indian Constitution and its Philosophy |
|Sources of Indian Constitution, its Preamble and Salient Features. |
| |
|Unit II: Constitutional Rights & Duties |
|Fundamental Rights: Right to Equality, Right to Freedom, Right against Exploitation, Right to Freedom of Religion, Cultural and Educational Rights, Right to |
|Constitutional Remedies |
|Fundamental Duties |
| |
|Unit III: Organs of Governance |
|Legislature: Parliament and its Composition; Qualifications and Disqualifications of Its members |
|Executive: President, Governor and Council of Ministers |
|Judiciary: Appointments, Qualifications, Powers and Functions of judges |
| |
|Unit IV: Local Administration and institutes for welfare |
|District Administration Head: Role and Importance; Municipalities: Introduction, Mayor and role of Elected Representative |
|Panchayati Raj Institutions: Introduction, Gram Panchayat, Panchayat Samiti and Zila Panchayat |
|Institutes and Bodies for the welfare of SC/ST/OBC and women |
| |
|TEXT / REFERENCE BOOKS: |
|The Constitution of India, 1950 (Bare Act), Government Publication. |
|Dr. S. N. Busi, Dr. B. R. Ambedkar. Framing of Indian Constitution, 1st Edition, 2015. |
|M. P. Jain, Indian Constitution Law, 7th Ed., Lexis Nexis, 2014 |
| |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
| |
|AUD 541C: PEDAGOGICAL STUDIES (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|The course will enable the student teachers: |
|To understand the concept of pedagogy and conceptual framework. |
|To gain insight on the meaning and nature of different pedagogies. |
|To determine aims and strategies of teaching- learning. |
|To understand the principals, maxims of successful teaching and the different methods of teaching. |
|Comprehend the need and importance of various devices of teaching and learning and their relationship between the two. |
|Point out and illustrate the difference between teaching and learning and their relationship between the two. |
|To appreciate that science/ engineering is a dynamic and expanding body of knowledge. |
|Course Outcomes: |
|Students will be able to understand: |
|It will improve teaching effectiveness of prospective teachers. |
|A prospective teacher will be able to design curriculum and assess the curriculum of their discipline in an effective way by understating the needs of the learners. |
|How can teacher education, school curriculum and guidance support effective pedagogy? |
|It will be functional for professional development among teachers. |
| |
|Syllabus contents: |
| |
|Unit I: Introduction and Methodology |
|Aims and Rationale, Conceptual Framework, Terminology related to Pedagogy |
|Contexts, Research Questions |
|Theories of Learning, Curriculum, Scope of Pedagogy |
| |
|Unit II: Teaching |
|Meaning and importance of Behavioral Objectives |
|Writing of Objectives in Behavioral Terms |
|Phases and Variables of Teaching |
|Principles, levels and maxims off teaching |
|Relationship between Teaching and Learning |
| |
|Unit III: Methods of Teaching |
|Methods: Inductive, Deductive, Project, Analytic, Synthetic, Brain Storming, Case Discussion |
|Concept and Significance of Individualized and Cooperative Teaching-Language Laboratory, Tutorials, Keller’s Plan (PSI), Computer Supporting Collaborative Learning |
|Mastery Learning: Concept, Basic Elements, Components and Types of Mastery Learning Strategies |
| |
|Unit IV: Evaluation Strategies |
|Evaluation in Teaching: Concept of Evaluation, Relationship between Teaching and Evaluation, Types of Evaluation (Formative and Summative) |
|Methods of Evaluation through Essay Type. Objective Type and Oral Method, Comparative merits and demerits of evaluation methods |
|Latest Trends in Evaluation |
| |
|TEXT / REFERENCE BOOKS: |
|Ackers J, Hardman F (2001) Classroom interaction in Kenyan primary schools, Compare, 31 (2): 245-261. |
|Agrawal M (2004) Curricular reform in schools: The importance of evaluation, Journal of |
|Curriculum Studies, 36 (3): 361-379. |
|Akyeampong K (2003) Teacher training in Ghana - does it count? Multi-site teacher education research project (MUSTER) country report 1. London: DFID. |
|Akyeampong K, Lussier K, Pryor J, Westbrook J (2013) Improving teaching and learning of basic maths and reading in Africa: Does teacher preparation count? International|
|Journal Educational Development, 33 (3): 272–282. |
|Alexander RJ (2001) Culture and pedagogy: International comparisons in primary education. Oxford and Boston: Blackwell. |
|Chavan M (2003) Read India: A mass scale, rapid, ‘learning to read’ campaign. |
|images/resource%20working%20paper%202.pdf. |
|Dyer C (2008) Early years literacy in Indian urban schools: Structural, social and pedagogical issues, Language and Education, 22 (5): 237-253. |
|Sharma N (2013) An exploration of teachers’ beliefs and understanding of their pedagogy, MPhil thesis, Mumbai: TATA Institute of Social Sciences. |
|Zeichner K, Liston D (1987) Teaching student teachers to reflect, Harvard Educational Review, 56 (1): 23-48. |
|Watkins C, Mortimore P (1999) Pedagogy: What do we know? In Mortimore P (ed.) Understanding pedagogy and its impact on learning. London: Paul Chapman Publishing. |
|Tyler R (1949) Basic principles of curriculum and instruction. Chicago: Chicago University Press. |
|Arends, R.1. ( 1 994) Learning to Teach, New York: McGraw-Hill. |
|Lunenberg M, Korthagen F, Swennen A (2007) The teacher educator as a role model, Teaching and Teacher Education, 23: 586-601. |
|Meena . Wilberforce E. Curriculum Innovation in Teacher Education: Exploring Conceptions among Tanzanian Teacher Educators. ÅBO AKADEMI UNIVERSITY PRESS, 2009. |
|Cooley, W. W., and Lohnes, P. R. (1976). Evaluation research in education. New York: Irvington. |
|Hassard, Jack, 2004, The Art of Teaching Science, Oxford Univesity Press. |
|Joyce, B., Weil, M., Calhoun, E. : (2000). Models of teaching, 6th edition, Allyn & Bacon. |
|Kyriacou, C. (2007) Effective teaching in schools – theory and practice. Cheltenham: Nelson Thornes. |
|Nye, B., Konstantopoulos, S. & Hedges, L.V. (2004) ‘How large are teacher effects?’ Educational evaluation and policy analysis, 26(3), 237-257. |
|National Staff Development Council. (2001). NSDC’s standards for staff development. Oxford, OH: Author. |
|Serpell, Z. & Bozeman, L. (1999). Beginning teacher induction: A report on beginning teacher effectiveness and retention. Washington, DC: National Partnership for |
|Excellence and Accountability in Teaching. |
| |
|NOTE: |
|Inthe semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|AUD543C: STRESS MANAGEMENT BY YOGA (AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|To achieve overall health of body and mind |
|To overcome stress |
|Course Outcomes: |
|Students will be able to: |
|1. Develop healthy mind and healthy body thus improving social health also |
|2. Improve efficiency |
|3. Improving “SQ” |
| |
|Syllabus contents: |
|Unit I: 1. Causes of stress, consequences of stress, diagnosis of stress, solution of reducing stress. |
|Difference and relation b/w Yog and Yoga, |
|benefits of meditation and Yoga, |
|Rules and Regulation of Yog and Yoga. |
|Empowerment of Soul and fitness of body. |
| |
|Unit II: 1. Do`s and Don’t’s in life. |
|How to be and not to be? |
|Understanding spirituality and materials. |
|Impact of: Truth at mouth/ Truth in thoughts. Non Violence outside / Compassion in thoughts, Celibacy (kamnayn- desire), purity of mind , non-covetousness, Cleanliness,|
|satisfaction, self study and surrender to almighty, Austerity, Penance |
| |
|Unit III: Role of Meditation in reducing Stress. Role of Yoga in reducing Stress. |
|Pranyama: AnulomVilom ,Ujjai, Costal Breathing, Abdominal Breathing, Sunyak, Kumbhak |
| |
|Unit IV: Asan: Sukhasana, Vajrasana, Padmasana, Swastik Asana, Ling Mudra, Gorakshasana, Talasana, Konasana, Trikonasana, Chakrasana, Utkatasana, Dhurva Asana, Garuda |
|Asana, Bhadrasana, Parvatasana, Yoga Mudra, Paschimottasana, Vakrasana, Gomukhasana, Bakasana, Tulasana, Matsyasana, Mayuri Asana, Bhujagasana, DhanurVakrasana, |
|PavanMuktasana, Viprtkarani, Makarasana, Shavasana, Dridasana, Yonimudra, Nauli, Dhenu Mudra. |
|TEXT / REFERENCE BOOKS: |
|‘Yogic Asanas for Group Tarining-Part-I”: Janardan Swami Yogabhyasi Mandal, Nagpur |
|“Rajayoga or conquering the Internal Nature” by Swami Vivekananda, AdvaitaAshrama, (Publication Department), Kolkata |
|“Value Education in Spirituality- Course-IV” by Brahma Kumaries Education Wing, Rajyoga Education Research Foundation, Mount Abu, Rajasthan. |
|“Stress Management for Dummies” by Allen Elkin, IDG Books India (P) Ltd. |
|“Yoga Courses for All” by Dr Hansraj Yadav, BhartyaVidyaBhawan, Mumbai |
|NOTE: |
|In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
|AUD 545C: PERSONALITY DEVELOPMENT THROUGH LIFE ENLIGHTENMENT SKILLS |
|(AUDIT COURSE 1 & 2) |
| |
|M. Tech. Semester – I/ II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25Marks |
| |
|2 |
|-- |
|-- |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|Course Objectives: |
|Students will be able to: |
|To learn and achieve the highest goal happily |
|To become a person with stable mind, pleasing personality and determination |
|To awaken wisdom in students |
|Course Outcomes: |
|The study of Shrimad-Bhagwad-Geeta will help the student in developing his personality and achieve the highest goal in life. |
|The person who has studied Geeta will lead the nation and mankind to peace and prosperity. |
|Study of Neetishatakam will help in developing versatile personality of students. |
| |
|Syllabus contents: |
| |
|Unit I: Holistic Development of Personality |
|Neetisatakam-Verses-19,20,21,22 (Wisdom), Verses-29, 31 32 (Pride and Heroism) ,Verses-26,28,63,65 (Virtue) |
|Unit II: Approach to Day to Day Work and Duties |
|Shrimad BhagwadGeeta: Chapter 2 (Verses- 41, 47, 48), Chapter 3 (Verses- 13, 21, 27, 35), Chapter 6 (Verses- 05, 13, 17, 23, 35), Chapter 18 (Verses- 45, 46, 48) |
|Unit III: Statements of Basic Knowledge |
|Shrimad BhagwadGeeta: Chapter 2 (Verses- 56, 62,68), Chapter 12 (Verses- 13, 14, 15, 16, 17, 18) |
|Unit IV: Personality of a Role Model |
|Shrimad BhagwadGeeta: Chapter 2 (Verses- 17), Chapter 3 (Verses 36, 37, 42), Chapter 4 (Verses 18, 38, 39), Chapter 18 ( Verses 37, 38 63) |
| |
|TEXT / REFERENCE BOOKS: |
|Srimad Bhagavad Gita by Swami SwarupanandaAdvaita Ashram (Publication Department), Kolkata |
|Bhartrihari’s Three Satakam (Niti-sringar-vairagya) by P.Gopinath, Rashtriya Sanskrit Sansthanam, New Delhi. |
|BhagvadGeeta- Prof. Satyavrata Siddhantalankar, Orient Publishing. |
| |
|NOTE: |
|Inthe semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all |
|selecting at least one from each unit. All questions will carry equal marks. |
|The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination. |
|Electronics gadgets including Cellular phones are not allowed in the examination. |
| |
| |
| |
| |
|BT502C GENOMICS AND PROTEOMICS |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|The objectives of this course are to make the students aware about: |
|The basic organization and arrangement of prokaryotic and eukaryotic genomes, significance of genome mapping, and the basic principles of different genome sequencing |
|techniques. |
|The various in-silico and experimental techniques used for structural and functional annotation of genomes, and to develop an understanding of transcriptome analysis. |
|To make the students develop an understanding of the protein profiling, identification, characterization, and interaction studies. |
|The applications of genomics and proteomics in human healthcare, and in the field of agriculture. |
|UNIT-I: Genome organization and mapping: Structural organization of prokaryotic, eukaryotic and organellar genomes; genome content- gene distribution and arrangement in|
|prokaryotes and eukaryotes; mapping genomes- genetic and physical mapping, molecular markers for construction of maps, restriction mapping, FISH, STS mapping. |
| |
|UNIT-II: Genome sequencing, analysis and annotation: Sequencing principle and techniques: automated, whole genome, and shotgun sequencing, clone-contig assembly, human |
|genome sequencing project; analysis of sequence data- finding gene location, recognition of coding and non-coding sequences, analysis of genetic variation, |
|determination of functions of individual genes, genome sequence annotation. |
|Transcriptomics Studying transcriptome by sequence analysis, SAGE, parallel signature sequencing, studying transcriptome by microarray analysis, mRNA profiling; |
|UNIT-III: Protein Expression Analysis: Protein analysis: protein profiling- 2-D separation of total cellular proteins, isolation and sequence analysis of individual |
|protein spots, MALDI-TOF for protein identification, protein characterization by mass spectrometry, protein expression analysis using microarrays. |
|Structural and Functional Proteomics: Structural analysis of proteins- X-ray crystallography and NMR spectroscopy; protein-protein interactions- phage display, yeast |
|two-hybrid system; analysis of protein complexes- affinity purification and mass spectrometry, metabolomics and systems biology. |
|UNIT-IV: Applications of genomics and proteomics: in research, human health care, and in agriculture, pharmacogenomics, high throughput screening in genome for drug |
|discovery and identification of gene targets, comparative genomics, future perspectives and developments. |
|COURSE OUTCOMES: |
|Students will develop an understanding of mapping & sequencing of whole genomes. |
|Students will understand the significance and means of structural and functional annotation of genomes. |
|Students will develop an in-depth understanding of transcriptomics and proteomics. |
|Students will understand how the study of genomics and proteomics help us in designing a better healthcare and agriculture system. |
|TEXT / REFERENCE BOOKS: |
|Brown TA, Genomes, 3rd Edition. Garland Science Pub (2006). |
|Campbell AM & Heyer LJ, Discovering Genomics, Proteomics and Bioinformatics, 2nd Edition. Pearson Education (2007). |
|Primrose S & Twyman R, Principles of Gene Manipulation and Genomics, 7th Edition, Blackwell (2006). |
|Sensen CW, Handbook of Genome Research, Vol. I and II. Wiley CVH. (2005). |
|Twyman RM, Principle of Proteomics. BIOS Scientific Publishers. (2004). |
|Kamp RM, Methods in Proteome and Proteome Analysis. Springer. (2004). |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
|BT504C PLANT MOLECULAR BIOLOGY |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|To study and familiarize the students with the basic cellular processes at molecular level and recent advances in the field of plant molecular biology for development |
|of transgenics for cropimprovement with desired traits which lead to commercial gains in agricultural biotechnology. |
|To gain theoretical knowledge on molecular basis of various plant processes and plant growth regulatory substances, secondary metabolite production and marker assisted |
|selection methods andplant genetic modifications for global food security. |
|UNIT-I: Genetic Engineering for Plant Metabolism: Introduction to plant genetic system; general organization of nuclear, mitochondria and chloroplast genomes; |
|structure, organization and regulation of nuclear genes; genetic interactions between nucleus, chloroplast and mitochondria; chloroplast and mitochondrial |
|transformation; .Arabidopsis in molecular biology. |
|Metabolic Engineering of Plant Secondary metabolism: Secondary metabolite production, plants as bioreactors, concept of biofactories; production of pharmaceutically |
|important compounds; crop plants for molecular farming. |
|UNIT-II: Molecular Mapping and Marker Assisted Selection (MAS): quantitative and qualitative traits; Fine mapping of genes/QTL; Map based gene/QTL isolation |
|anddevelopment of gene based |
|markers; Allele mining by TILLING and Eco-TILLING; Use of markers in plant breeding , MAS for genes of agronomic importance, eg., insect resistance, grain quality and |
|grain yield; molecular polymorphism; RFLP, RAPD, STS, AFLP, SNP markers; construction of genetic and physical map. |
|UNIT-III: Plant Genetic Modification and Plant Proteomics: Gene isolation, plant transformation technology, gene transfer methods: Indirect Methods: Agrobacterium |
|mediated transformation, Role of vir genes,Direct methods : Biolistics, physical and chemical methods,, control and silencing of transgenic expression, screenable and |
|selectable markers, and characterization of transgenics; plant proteomics: protein separation, identification and quantification. |
|UNIT-IV: Genetic Modifications for Crop Improvement: Biotic and abiotic stress resistance/ tolerance; quality improvement:: modification for higher carbohydrate, |
|protein and oil content; molecular basis of abiotic stress; antisense gene approach; ribozyme approach; terminator seed technology; Golden rice, FlavrSavr tomato (a |
|case study); plant-derived vaccines. |
|COURSE OUTCOMES: |
|After successful completion of this course students are expected to be able to: |
|To gain widening of knowledge with modern plant biotechnology processes, including genetic engineering of plant metabolism for production of plants with improved |
|characteristics. |
|To carry plant genetic modifications with desirable characteristics and knowledge of plant proteomics. |
|TEXT/ REFERENCE BOOKS: |
|Handbook of Plant Biotechnology, Vol. I and II. By Paul Christou and Harry Clee. John Wiley and Sons, Ltd |
|Slater A., Scott N., and Fowler M. Plant biotechnology: the genetic manipulation of plants. 1st edition. Oxford University press. 2003. |
|Chrispeels M.J. and Sadava D. Plants, genes and crop biotechnology. 2nd edition. American society of plant biologists. Jones and Bartlett Publishers, USA. 2003. |
|Altman A. and Dekker, M. Agricultural biotechnology. 2001. |
|Biochemistry and molecular biology of plants. Edited by Buchanan, Gruissem and Jones. American Society of Plant Biologists, USA. 2000. |
|Specific journals and published references. |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five questions |
|in all, selecting at least one from each unit. All questions will carry equal marks. |
|BT506C GENOMICS AND PROTEOMICS LAB |
| |
|M. Tech. Semester – II (BIOTECHNOLOGY) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|-- |
|4 |
|2 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|The objectives of this course is to provide a hands-on-training to the students with regard to working with various |
|softwares and programmes used for structural & functional annotation of genomes, and for proteomics research. |
| |
|List of Experiments/ Exercises: |
| |
|Retrieval of full-length genome sequences for genome annotation. |
|Gene prediction using Glimmer/EasyGene/ GeneMark/ ChemGenome. |
|tRNA prediction using tRNA scan. |
|Genome annotation using DNAMaster. |
|Phylogenetic tree construction using MEGA 6.0. |
|Retrieval of protein structures from PDB. |
|Protein sequence analysis using ExPasy proteomic tools. |
|Protein secondary structure prediction using PredictProtein. |
|Protein molecular visualization using Swiss-Pdb Viewer |
|Homology modelling of proteins. |
| |
|COURSE OUTCOMES: |
|After successful completion of this course students are expected to be able to: |
|To use bioinformatic tools and softwares for planning and executing basic research in the field of genomics & proteomics. |
| |
|TEXT /REFERENCE BOOKS: |
|Bioinformatics: A Practical Approach by K. Mani and N. Vijayaraj, Aparna Publications, Coimbatore. |
|Bioinformatics. Higgins & Taylor (2000). OUP. |
|3. Pennington SR, Dunn MJ, “Proteomics from Protein Sequence to Function”, Viva Books Ltd, 2002 |
|4. David W Mount, “Bioinformatics: Sequen |
|5. Leach A.R. , “Molecular Modelling - Principles and Applications”, 2nd Edition, Prentice Hall, 2001. |
| |
| |
|Note: The students will be required to perform 08 experiments/ exercises from the above list and the other two experiments may be designed by the department based on |
|the related theory course. |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|BT508C PLANT MOLECULAR BIOLOGY LAB |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|-- |
|4 |
|2 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To give students hands-on experience and training in characteristic plant molecular biology techniques, understanding the role of particular organelles within the cell.|
| |
|To demonstrate various steps of Agrobacterium mediated genetic transformation for development of transgenic plant, their confirmation at molecular level for the |
|expression of foreign protein. |
| |
|List of Experiments/ Exercises: |
|To isolate protoplasts from flower petals and leaves of different plants and demonstrateprotoplast fusion via PEG. |
|To extract proteins from the given plant material and estimate soluble protein content by Bradford method. |
|To carry out homogenization of leaves and sub-cellular fractionation by differential centrifugation and chloroplast purification. |
|To resolve proteins by SDS-PAGE to identify major chloroplast proteins. |
|To isolate plant DNA from different sources and digest DNA with restriction enzymes and to compare DNA agarose gel electrophoresis of various plant species. |
|To extract RNA and agarose gel electrophoresis of RNA. |
|To perform RAPD analysis of two varieties of Brassica or any other genera. |
|To maintain and grow Agrobacterium cultures. |
|To demonstrate pre-culture and agro-infection for Agrobacterium-mediated gene delivery. |
|To study the expression of GUS gene by histochemical methods. |
|To compare PCR amplified DNA of control plants and transgenic plants. |
|To analyze the transgenic plants for the expression of foreign protein by Western blotting. |
| |
|COURSE OUTCOMES: |
|After successful completion of this course students are expected to be able to: |
|To learn the technical know-how of plant molecular biology lablike chloroplast purification and protoplast fusion using PEG methodand learning of detailed procedure for|
|development of transgenic plants through indirect method like Agrobacterium mediated genetic transformation. |
| |
|TEXT/ REFERENCE BOOKS: |
|Sambrook J, DW Russell, T Maniatis. 2001. Molecular Cloning: a Laboratory Manual. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press, c2001. 3rd Edition. |
|Ausubel F [et al.]. 2001. Current Protocols in Molecular Biology. New York: John Wiley & Sons. 5 volumes. (Loose-leaf) |
|George EF, Hall MA & De Klerk GJ. 2008. Plant Propagation by Tissue Culture. Agritech Publ. |
|Pena L. 2004. Transgenic Plants: Methods and Protocols. Humana |
|Bhojwani SS. 1983. Plant Tissue Culture: Theory and Practice. Elsevier. |
|Christou P & Klee H. 2004. Handbook of Plant Biotechnology. John Wiley & Sons. |
|P K Jaiwal (ed), Plant Genetic Engineering Vols. 7 & 8: Metabolic Engineering andMolecular Farming- I and II, Stadium Press LLC, USA. 2006. |
| |
| |
| |
| |
| |
| |
| |
|BT510C : MINI PROJECT |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|Examination |
|: |
|: |
|25 Marks |
|75 Marks |
| |
|-- |
|4 |
|2 |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|The objective of mini project is to develop in students the professional quality of employing technical knowledge obtained in the field of Biotechnology through a |
|project work involving review/analysis augmented with creativity, innovation and ingenuity. |
| |
|The student shall take up investigative study on a topic in the broad relevant field of biotechnology, involving literature review/software-work/ lab-work, to be |
|assigned by the department on an individual basis, under the guidance of a supervisor from the department. This is expected to provide a good initiation for the |
|student(s) in R&D work. |
| |
|The activities under mini project may normally include: |
|Literature survey on an assigned topic. |
|Working out a preliminary approach to the problem relating to the assigned topic. |
|Conducting preliminary analysis/experiment-design. |
|Compilation of the work and presenting it in two seminar talks in the semester, before a committee having M.Tech. coordinator and supervisor(s). |
|Submit a written spiral-bound report on the work undertaken to the M.Tech. Coordinator. |
| |
|Internal evaluation of Mini Project will be done at the end of the semester through a seminar by the committee consisting of the following: |
|1. Chairperson/Head of Department/ Nominee : Chairperson |
|2. M.Tech. Coordinator : Member-Secretary |
|3. Respective Project Supervisor(s) : Member(s) |
| |
|Final exam.will be conducted by the internal examiner (M.Tech. Coordinator / faculty nominated by Chairperson) and external examiner to be appointed by Controller of |
|Examinations from a Panel of Examiners submitted by the Dept. |
| |
|M.Tech. coordinator will be assigned a load of 1 hour per week excluding his/ her own guiding load. Project supervisor (guiding teacher) will be assigned a load of 1 |
|hour per week per student subject to a maximum load of 2 hours. |
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|BT522C MOLECULAR MODELLING AND DRUG DESIGNING (Elective III) |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|4 |
|-- |
|4 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|The principle, fundamentals of molecular modelling will be understood. |
|Both the science of drug discovery and active drug targets will be discussed. |
|UNIT–I: Concepts of molecular structure (bond length, bond angle, torsion angle and non-covalent |
|interactions),Internal energy, Minimization of energy of small molecules, Empirical representation of |
|molecular energies, Use of force fields and the molecular mechanics method, Discussion of global energy |
|minimum, Molecular representation in graphics. |
| |
|UNIT–II: Basic principles of molecular dynamics and Monte Carlo Simulation for conformational analysis - ab |
|initio, Density, Functional Theory and semiemperical methods. |
| |
|UNIT–III: Macromolecular modeling :Identification and mapping of active sites, Drug-receptor interactions,Docking, |
|Binding studies, QSAR analysis and their Implications to the 3-D modeler. 2-D and 3- D database |
|searching, pharmocophore identification and novel drug design. |
| |
|UNIT–IV: Basic concept of Enzymes, Theories of enzyme inhibition, Enzyme inhibition as a tool for drug |
|development, Structured based drug design, Structural bioinformatics in drug discovery. Cancer and |
|related diseases, Mechanism of action of anti-cancer drugs, New targets for anti-cancer drugs. |
| |
|COURSE OUTCOMES: |
|Understanding of drug principles and molecular targets of selected groups of clinically important drugs |
|Understanding of enzyme theories for drug designing and drug targets studies. |
|TEXT / REFERENCE BOOKS: |
|Molecular Modelling: Principles and Applications (2nd Edition), Andrew Leach, Addison Wesley Longman, |
|Essex, England, 1996. |
|Modelling Molecular Structures, 2nd Edition, Alan Hinchliffe, John-Wiley, 2000. |
|Molecular Modelling for Beginners, Alan Hinchliffe, John-Wiley, 2003. |
|Guide Book on Molecular Modeling in Drug Design,N. Cohen (Ed.), Academic Press, San Diego, 1996. |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
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|BT524C BIOTECHNOLOGY IN HEALTHCARE (Elective III) |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|4 |
|-- |
|4 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To ensures the students to understand about the microbiology and diseases |
|This advanced course aims to extend your understanding and appreciation of interactions between microorganisms and parasites; antimicrobial agents and microbial |
|resistance; characteristics of viruses, medically-important fungi, pathogenesis and diagnosis of viral infections; infections of the skin and respiratory tract. |
|To understand the mechanism of immune system. |
| |
|UNIT–I: Biology of Infectious diseases: Disease Burden- medically important diseases caused by bacteria, viruses, fungi and parasites, studies of some representative |
|diseases like AIDS, typhoid, tuberculosis, cancer, hepatitis, influenza and dermatophytic diseases. |
| |
|UNIT–II: Immune system and Immune Response: Immune system- overview, humoral and cell mediated immune responses, antigen & antibodies, structure & function |
|transplantation, hypersensitivity, cancer, & autoimmunity. |
| |
|UNIT–III: Therapeutics: Oligonucleotides- gene therapy, antisense therapy, ribozyme, oligosaccharides- glycoproteins, polysaccharides, bacterial vaccines, carbohydrate-|
|based cancer vaccines, oligopeptides- endogeneous peptides and proteins with modifications. radiological agents- radiosensitizers and radioprotective agents, Drug |
|targeting- basic concepts & novel advances |
| |
|UNIT–IV: Recent developments in genomics and pharmaceutical sciences: Sequencing of human genome, brief account of repetitive sequences present in human genome, human |
|genome project, latest developments in human genetics. Chemotherapeutic agents- synthetic antibacterial agents, antifungal, anti- protozoal, antiviral agents, endocrine|
|drugs- sex hormones and analogs, agents affecting the immune response, cardiovascular drugs- hematopoietic agents, anticoagulants, antithrombotics etc., |
|COURSE OUTCOMES: |
|Demonstrate an awareness of the global burden of infectious diseases and understand its impact on world health and future implications for under-developed |
|countries . |
|Demonstrate a basic understanding of the pathogenesis of some important infections of humans, and be able to identify the causative agents. |
|Demonstrate an understanding of the importance of the factors that influence vaccine design and development. |
|TEXT / REFERENCE BOOKS: |
|Christine M. and Bladon John Pharmaceutical Chemistry. Wiley & Sons, Ltd. (2002). |
|Manfred E.,Wolff. Burger’s Medicinal Chemistry and Drug Discovery (5th edition). A Wiley Sons, Inc. (2000). |
|Gritje Molema and Dirk K. F. Meijer. Drug Targeting Organ-Specific Strategies. Wiley (2002). |
|Ananthanarayanan R. and Jayaram C.K. Panuker Textbook of Microbiology R, Drient Longman. |
|Immunology by kuby JWH Freeman and company, New York. |
|Jawetz. Review of Medical Microbiology. |
|Specific Journals and published references. |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
|BT526C: BIOENERGY AND BIOCHEMICAL TECHNOLOGY (Elective III)) |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|COURSE OBJECTIVES: |
|Impacts of biofuels production/consumption on climate change. |
|Biofuel applications in the developing world for indigenous development. |
|Food/Organic Waste Recycling and Biomass Valorization. |
|Agricultural Waste Processing and Recycling |
| |
|UNIT-I: Energy perspective: Current methods, Biomass possibilities; Fundamental concepts in understanding biofuel and bioenergy production: Mass Balances, Energy |
|Balances, Thermodynamics, Organic compounds, Chemistry of plant materials; Production of biorenewable resources: Herbaceous crops, Woody crops, Algae, Conversion of |
|biomass into heat and power, Direct combustion, Thermal gasification, Anaerobic digestion |
| |
|UNIT-II: Processing of biomass into chemicals and fuels: Sugars, Alcohols, Biodiesel, Thermochemical conversion, |
|Fischer Tropsch Fuels; Environmental impact of the bioeconomy: Land use, Pollution, Climate change; |
|Economics of biorenewable resources: Feedstock costs, Capital costs, Operating costs. |
| |
|UNIT-III: Process calculations: Basic concepts. Fundamentals of material and energy balance for processes |
|with/without chemical reaction. Simultaneous mass and energy balance in flow and without flow |
|conditions. Microbial nutrition: Nutritional requirements for growth and product formation. Medium |
|design and optimization with statistical analysis (ANOVA), Placket-Burman and Central Composite |
|Design technique. Pre-treatment of industrial raw materials. |
| |
|UNIT-IV: Bioreactor operations: Different types of bioreactors, configuration of Bioreactors and their main |
|components. Modes of bioreactor operation. Important bioreactor accessories. Fermentation overview: |
|Inoculum development. Various types of Fermentation, submerged fermentation, aerobic and anaerobic |
|fermentation. Overview of biosynthetic mechanisms. Metabolic stoichiometry. |
|COURSE OUTCOMES: |
|see alternative and cheaper sources of energy. |
|Utilization of bioresource for sustainable development. |
|TEXT/ REFERENCE BOOKS: |
|Biorenewable Resources – Engineering New Products from Agriculture; Author: Robert C. Brown Publisher: Blackwell Publishing Professional, 2003; ISBN: 978-0-8138-2263-1 |
|Biofuels; Author: Wim Soetaert and Erik Vandamme (Editors), Publisher: Wiley ISBN: 978-0-470-02674- |
|8 Year: 2009 |
|Biomass for Renewable Energy, Fuels, and Chemicals; Author: Donald Klass Publisher: Academic Press ISBN: 978-0-12-410950-6 Year: 1998 |
|C. Ratledge & B. Kristiansen, "Basic Biotechnology" 3rd Edn. Cambridge University Press (2008). |
|P.M.Doran, "Bioprocess Engineering Calculations", Elsevier India Pvt Ltd (2008). |
|Peter F. Stanbury, Stephen J. Hall & A. Whitaker, "Principles of Fermentation Technology", Elsevier India Pvt Ltd.(2007). |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five |
|questions in all, selecting at least one from each unit. All questions will carry equal marks. |
|BT528C ANIMAL CELL CULTURE TECHNOLGOY(Elective IV) |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|4 |
|-- |
|4 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
| |
| |
|COURSE OBJECTIVES |
|Provide knowledge and expertise in animal and plant cell and tissue culture theory and practices. |
|Significant role from modifying animals and plants in biotechnology to propagate endangered animals by modifying cell in biotechnology and to propagate all lines for |
|use in microbiological, medical, and biochemical research. |
| |
|UNIT –I: Lab Equipment and Media of Animal cell culture: Planning, construction and services, aseptic concepts, maintenance of sterility, cell culture vessels, |
|common cell culture contaminants, cell culture media, serum free media, maintenance of the culture and cell lines, detection of contamination and laboratory management.|
|UNIT-II: Different Types of Cell Cultures: History of animal cell culture, types of primary culture, chicken embryo fibroblast culture, chicken liver and kidney |
|culture, secondary culture, trypsinization, cell separation, continuous cell lines, suspension culture, monolayer culture etc., behavior of cells in culture conditions:|
|division, growth pattern, metabolism of estimation of cell number, development of cell lines, characterization and maintenance of cell lines, cryopreservation of animal|
|cell lines. |
|UNIT-III: Characteristics of Animal Cells: Metabolism, regulation and nutritional requirements for mass cultivation of animal cell cultures, kinetics of cell growth and|
|product formation and effect of shear force, product and substrate transport, micro & macro-carrier culture, hybridoma technology, Cloning in animals, genetic |
|engineering in animal cell culture. |
|UNIT-IV: Cell Culture Technology: integration of DNA into mammalian genome, viral vectors, shuttle vectors of other viruses, gene cloning methods in cell lines, stem |
|cell culture, embryonic stem cells and their applications. |
|Tansgenics and Gene Therapy: Transgenics and gene knockout technology, objectives of gene transfer, vectors, gene constructs, promoters, transfection methods, embryonic|
|stem cell transfer, targeted gene transfer, transgene integration, detection of transgenic and of trans gene function, transgenic animals produced, ethical issues |
|related to transgenic animals, gene therapy. |
|COURSE OUTCOMES |
|1. At the end of the course, the students will have sufficient scientific understanding of the Animal Tissue |
|Culture techniques, knowledge of aseptic handling of cell lines. Use of these techniques in various fields of |
|research and medicine and human welfare. |
|TEXT / REFERENCE BOOKS: |
|Genes VIII by Benjamin Lewin, 2004 |
|Gene transfer to animal cell by R.M. Twyman, 2005 |
|Animal cloning by Joseph Pano, 2005 |
|Analysis of gene and genome by Richard J. Reece, 2004 |
|Animal Biotechnology M.M. Ranga, Agrobios Publishers, India, 2003 |
|A Text book of Biotechnology, Dubaey, R. C. 1993, S. Chand & Co. New Delhi |
|Principles of Gene Manipulations: An Introduction to Genetic Engineering, Blackwell Sci. Publ. |
|Biotechnology, KalyaniPublishrs, New Delhi |
| |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt |
|five questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
|BT530C BIODIVERSITY AND BIORESOURCE TECHNOLOGY (Elective IV) |
| |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To provide overview of fundamentals of biodiversity and bioresources available through reading assignments and homework sets. |
|Emphasis is given on current availability of commercial products and services so that students can exploit the knowledge and their creativity to imporove the existing |
|scenario. |
|UNIT-I: Concept and Principles: Genetic diversity, molecular taxonomy, species and population biodiversity, origin of biodiversity/evolution, definition of |
|biodiversity, types of biodiversity, levels of biodiversity, genetic resources, conservation of biodiversity, endangered species, impact of pollution on biodiversity. |
| |
|UNIT-II: Biodiversity Loss: Causes and consequences of biodiversity loss, habitual loss and alteration, endangered species/exotic species, preventing biodiversity loss,|
|conservation of biodiversity- need and types, role of biotechnology in biodiversity conservation, in vitro conservation. |
|Biodiversity Management: Identifying land for natural resources, managing wild life resources, bio-diversity and germplasm- germplasm conservation, classical and new |
|approaches, collection and exchange of germplasm, cryopreservation, stability of conserved germplasm. |
| |
|UNIT-III: Tools to Study Biodiversity: DNA extraction from different species and preserved specimens, screening methods- isozymes, RFLP analysis, DNA fingerprinting, |
|PCR, RAPDs, AFLP, data analysis- measure of polymorphisms within and among populations, bioprospecting of microbial, animal and plant biodiversity resources in India. |
| |
|UNIT-IV: Bioresource Technology: An overview of commercial products/ services through process biotechnology, issues pertaining to development of biotechnology, general |
|aspects related to the quality control of bioprocesses, health hazards in biotechnology and containment, biosafety considerations and containments, sources of gene |
|escape, ecological risks of genetically modified plants, implications of intellectual property rights on the commercialization of biotechnology products. |
| |
|COURSE OUTCOMES: |
|Pupils should thoroughly understand the depletion rate of biodiversity and think of use of emerging technologies for sustainable of bio resources. |
| |
|TEXT / REFERENCE BOOKS: |
|Kumar, U. and Sharma, A. K. Plant biotechnology and Biodiversity conservation. Agrobios (India). |
|Dobson, A. Conservation and biodiversity. Plgrave macmillon. |
|Primack, R.B. Essentials of conservation Biology. 3rd Edition. Sinauer Associates, Inc. Publishers. W.K. |
|Molecular tools for Screening Biodiversity. Ed. Angela Karp, Peter G. Isaac and David S. Ingram. Chapman & Hall. |
|Purves, W. K., Sadava, D., Orians, G. H. and Heller, H. C. Life. Sinauer Associates Inc; & W.K. Freeman and Company. |
| |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five questions |
|in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
|BT532C METABOLIC ENGINEERING (Elective IV) |
|M. Tech. Semester - II (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|3 |
|-- |
|3 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
|COURSE OBJECTIVES: |
|To provide insightful information about cellular processes and ways to understand production processes of proteins and secondary metabolites under in-vivo conditions. |
|Also to understand engineering strategies to manipulate cellular pathways for exploitation of cell mechanisms to overproduce the desired molecules. |
| |
|UNIT-I: Introduction: Identification of metabolic regulation, basic concepts of metabolic engineering- overview of cellular metabolism, different models for cellular |
|reactions, feedback regulation, synthesis of primary metabolites, amino acid synthesis pathways and its regulation at enzyme level and whole cell level, alteration of |
|feedback regulation, limiting accumulation of end products. |
| |
|UNIT-II: Biosynthesis of Secondary Metabolites: Regulation of secondary metabolite pathways, precursor effects, prophase, idiophase relationship, catabolite regulation|
|by passing control of secondary metabolism, producers and applications of secondary metabolites, bioconversions-an introduction. |
| |
|UNIT-III: Regulation of Enzyme Production: Strain selection, genetic improvement of strains, metabolic pathway manipulations to improve fermentation, catabolite |
|repression, optimization and control of metabolic activities, modification of existing – or the introduction of entirely new metabolic pathways, metabolic flux – |
|distribution, analysis and applications. |
| |
|UNIT-IV: Applications of Metabolic Engineering: Application in pharmaceuticals, chemical bioprocesses, food technology, agriculture, environmental bioremediation and |
|biomass conversion. |
|Metabolic engineering with Bioinformatics: Metabolic pathway modeling, analysis of metabolic control and the structure metabolic networks, metabolic pathway synthesis |
|algorithms. |
| |
|COURSE OUTCOMES: |
|Ability of the engineers for designing stratigies to modify cellular behabiour based on concepts understood for production of secondary metabolites and enzymes. |
| |
|TEXT / REFERENCE BOOKS: |
|Wang, D.I.C., Cooney C.L., Demain A.L., Dunnil, P., Humphrey, A.E. and Lilly M.D. Fermentation and Enzyme Technology. John Wiley and Sons. 1980. |
|Stanbury P.F., and Whitaker A., Principles of Fermentation Technology, Pergamon Press, 1984. |
|Specific journals and published references. |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five questions|
|in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
| |
| |
| |
|BT601C ADVANCES IN APPLIED BIOTECHNOLOGY |
| |
|M. Tech. Semester - III (Biotechnology) |
| |
| |
|L |
|P |
|Credits |
| |
|Class Work |
|: |
|25 Marks |
| |
|4 |
|-- |
|4 |
| |
|Examination |
|: |
|75 Marks |
| |
| |
| |
| |
| |
|Total |
|: |
|100 Marks |
| |
| |
| |
| |
| |
|Duration of Examination |
|: |
|3 Hours |
| |
| |
| |
|UNIT-I: Advances in Agricultural Biotechnology: Molecular breeding: Role of molecular markers (RAPD, SSR, AFLP etc) in crop and farm animal improvement, marker assisted|
|selection; QTL mapping, RNAi, virus induced gene silencing. Genetic engineering of plants: Molecular and biochemical basis of various abiotic stresses like drought, |
|salinity, heavy metals, high temperature etc.; production of transgenic plants for fungal, bacterial and viral disease resistance; modification of nitrogen fixing |
|capabilities; gene pyramiding, chloroplast genetic engineering. Molecular farming: Use of plants and animals for production of neutraceuticals, edible vaccines and |
|other desired products. |
| |
|UNIT-II: Advances in Medical Biotechnology: Disease Diagnosis: Biotechnological techniques for earlier detection and improved diagnosis of human genetic predisposition |
|to diseases, diagnosis through ligase chain reaction, neoplastic disease diagnosis. Therapeutics: Therapeutic agents, biotechnological techniques for development of |
|drugs, rational drug design, gene therapy, pharmacogenomics ("custom drugs"). Drug synthesis: Natural products, endogenous hormones, molecular principles and advances |
|in drug targetting and drug delivery, controlled release systems, site specific delivery- different techniques. |
| |
|UNIT-III: Advances in Environment Biotechnology: Global Environmental Problems: Ozone depletion, UV-B and greenhouse effect, acid rain, environmental pollution, |
|its impact and biotechnological approaches for management, ecofarming. Biotechnology for pollution management: Biotechnological advances in pollution control through |
|GEMs, newer approaches to sewage treatment- treatment of liquid and solid waste, microbes in deodorization and desulphurization, biotechnology of transformation of |
|xenobiotics, mineral leaching, and microbial enhanced oil recovery. Environment and Energy: Bioenergy, biotechnology of biofuels and biofertilizers, fuel alcohol |
|production, hydrogen gas production, biogas technology, factors affecting bioenergy production and its status in India. |
| |
|UNIT-IV: Advances in Industrial Biotechnology: Industrial production of primary and secondary metabolites: Advances in the production of commercially important organic |
|acids, amino acids and alcohols; antibiotics, beta lactams, aminoglycosides, macrolides, vitamins and steroids. Industrial production of enzymes and other bioproducts: |
|Production of industrial enzymes (proteases, amylases, lipases, cellulases etc.), eco- friendly agricultural chemicals, biopesticides, biofertilizers, biopreservatives,|
|biopolymers and single cell protein, role of microbial enzymes in various industrial processes. Industrial production of modern biotechnology products: Production of |
|recombinant proteins having therapeutic and diagnostic applications, vaccines and monoclonal antibodies, products of plant and animal cell culture, biotransformations |
|and bioaugmentation. |
| |
| |
| |
| |
| |
| |
|TEXT/ REFERENCE BOOKS: |
|Arie Altman. Agricultural Biotechnology, Marcell Dekker, Inc, (2001). |
|Chrispeels, M.J. and Sadava, D.E. Plants, Genes and Crop biotechnology, 2nd Edition, American Society of Plant Biologists, Jones Bartlett publishers. (2003). |
|Baron E.J., Peterson L.R. and Finegold S.M. Mos, Bailey and Scott’s Diagnostic Microbiology, (1990). |
|Jawetz et. al. Medical Microbiology. |
|P. Odum: Fundamentals of Ecology. |
|Amann, R.I. Stromley, J. Stahl: Applied and Environmental Microbiology. |
|Varma and Agarwal: Environmental Biology. |
|Asthana and Asthana: Environment Problems and Solutions. |
|Casida, L.E. Industrial Microbiology. New Age International (P) Ltd. New Delhi. (1998). |
|Crueger, W. and Crueger, A. Biotechnology: A Textbook of Industrial Microbiology 2nd Edition. Panima Publishing Corporation, New Delhi. (2000). |
| |
|Note: In the semester examination, the examiner will set 08 questions in all, selecting two from each unit. The candidates will be required to attempt five |
|questions in all, selecting at least one from each unit. All questions will carry equal marks. |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|MTOE 651C: BUSINESS ANALYTICS (OPEN ELECTIVE) |
|M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
The main objective of this course is to give the student a comprehensive understanding of business analytics methods
1. Understand the role of business analytics within an organization.
2. Business Analytics industry sequence is to familiarize the students with the concept of Data Analytics (Big Data) and its applicability in a business environment
3. Analyze data using statistical and data mining techniques and understand relationships between the underlying business processes of an organization.
4. To gain an understanding of how managers use business analytics to formulate and solve business problems and to support managerial decision making.
5. To become familiar with processes needed to develop, report, and analyze business data.
6. Use decision-making tools/Operations research techniques.
7. Mange business process using analytical and management tools.
Analyze and solve problems from different industries such as manufacturing, service, retail, software, banking and finance, sports, pharmaceutical, aerospace etc
Course Outcomes:
1. At the end of the Fall semester, students should have acquired an understanding of Analytics – the terminology, concepts and familiarity of potential tools and solutions that exist today Students will demonstrate knowledge of data analytics.
2. Students will demonstrate the ability of think critically in making decisions based on dataand deep analytics
3. Students will demonstrate the ability to use technical skills in predicative and prescriptivemodeling to support business decision-making
4. Students will demonstrate the ability to translate data into clear, actionable insights. student should be better familiar with overall analytics tools/techniques and their use in corporate
Syllabus contents:
UNIT I: Business analytics: Overview of Business analytics, Scope of Business, analytics, Business Analytics Process, Relationship of Business Analytics, Process and organisation, competitive advantages of Business Analytics. Statistical Tools: Statistical Notation, Descriptive Statistical methods, Review of probability distribution and data modelling, sampling and estimation methods overview.
UNIT II: Trendiness and Regression Analysis: Modelling Relationships and Trends in Data, simple Linear Regression, Important Resources, Business Analytics Personnel, Data and models for Business analytics, problem solving, Visualizing and Exploring Data, Business Analytics Technology.
UNIT III: Organization Structures of Business analytics, Team management, Management Issues, Designing Information Policy, Outsourcing, Ensuring Data Quality, Measuring contribution of Business analytics, Managing Changes. Descriptive Analytics, predictive analytics, predicative Modelling, Predictive analytics analysis, Data Mining, Data Mining Methodologies, Prescriptive analytics and its step in the business analytics Process, Prescriptive Modelling, nonlinear Optimization.
UNIT IV: Decision Analysis: Formulating Decision Problems, Decision Strategies, with the without Outcome Probabilities, Decision Trees, the Value of Information, Utility and Decision Making.
Forecasting Techniques: Qualitative and Judgmental Forecasting, Statistical Forecasting Models, Forecasting Models for Stationary Time.
TEXT / REFERENCE BOOKS:
1. Project Management: The Managerial Process by Erik Larson and, Clifford Gray
2. Business Analysis by James Cadle et al.
3. Bajpai Naval, Business Statistics, Pearson, New Delhi.
4. Whigham David, Business Data Analysis, Oxford University, Press, Delhi.
5. Predictive Analytics: The Power to Predict Who Will Click, Buy, Lie or Die. Eric Siegel.
6. Big Data, Analytics and the Future of Marketing and Sales. McKinsey.
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronics gadgets including Cellular phones are not allowed in the examination.
|MTOE653C: INDUSTRIAL SAFETY (OPEN ELECTIVE) |
| M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
Course Outcomes:
Syllabus contents:
UNIT I: Industrial safety: Accident, causes, types, results and control, mechanical and electrical hazards, types, causes and preventive steps/procedure, describe the salient points of factories act 1948 for health and safety, washrooms, drinking water layouts, light, cleanliness, fire, guarding, pressure vessels, etc., Safety color codes. Fire prevention and firefighting, equipment and methods.
Fundamentals of maintenance engineering: Definition and aim of maintenance engineering, Primary and secondary functions and responsibility of the maintenance department, Types of maintenance, Types and applications of tools used for maintenance, Maintenance cost & its relation to replacement economy, Service life of the equipment.
UNIT II: Wear and Corrosion and their prevention: Wear- types, causes, effects, wear reduction methods, lubricants-types and applications, Lubrication methods, general sketch, working and applications, (i). Screw down grease cup, (ii). Pressure grease gun, (iii). Splash lubrication, (iv). Gravity lubrication, (v). Wick feed lubrication (vi). Side feed lubrication, (vii). Ring lubrication, Definition, principle and factors affecting the corrosion. Types of corrosion, corrosion prevention methods.
UNIT III: Fault Tracing: Fault tracing-concept and importance, decision tree concept, need and applications, sequence of fault finding activities, show as decision tree, draw decision trees for problems in machine tools, hydraulic, pneumatic, automotive, thermal and electrical equipment’s like, (i). Any one machine tool, (ii). Pump (iii). Air compressor, (iv). Internal combustion engine, (v). Boiler, (vi). Electrical motors, Types of faults in machine tools and their general causes.
UNIT IV: Periodic and Preventive Maintenance: Periodic inspection-concept and need, degreasing, cleaning and repairing schemes, overhauling of mechanical components, overhauling of electrical motor, common troubles and remedies of electric motor, repair complexities and its use, definition, need, steps and advantages of preventive maintenance. Steps/procedure for periodic and preventive maintenance of: (i). Machine tools, (ii). Pumps, (iii). Air compressors, (iv). Diesel generating (DG) sets, Program and schedule of preventive maintenance of mechanical and electrical equipment, advantages of preventive maintenance. Repair cycle concept and importance.
TEXT / REFERENCE BOOKS:
|1 |Maintenance Engineering Handbook |Higgins & Morrow |Da Information Services |
|2 |Maintenance Engineering |H. P. Garg |S. Chand and Company |
|3 |Pump-hydraulic Compressors, |Audels |Mcgraw Hill Publication |
|4 |Foundation Engineering Handbook |Winterkorn, Hans |Chapman & Hall London. |
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronics gadgets including Cellular phones are not allowed in the examination.
|MTOE 655C: OPERATIONS RESEARCH (OPEN ELECTIVE) |
| M. Tech. Semester - III (Biotechnology) |
| |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
1. To develop modeling skills in students.
2. To develop skill in students for efficient designing analysis and control of complete system.
3. To make students capable of formulating the practical problems into mathematical problems.
4. To acquaint student with linear as well as non-linear programming problem and their application.
Course Outcomes:
1. Students will be able to apply the dynamic programming to solve problems of discrete and continuous variables.
2. Students will be able to carry out sensitivity analysis.
3. Student will be able to model the real world problem and simulate it.
4. The students will be able to carry forward the operation research techniques in practical problems.
Syllabus contents:
UNIT I: Linear optimization methods: General mathematical model formation of L.P.P, its solution by Graphical method, Simplex method, big –M method, two phase method sensitivity analysis (change in cj, bj&aij’s)
Revised Simplex method.Concept of duality, formation of Dual L.P.P, advantage of Duality, dual simplex method, parametric programming.
UNIT II: Non liner programming: NLPP Mathematical formulation and solution with equally constraints, Lagrange’s method, Graphical method, Kuhn—Tucker necessary &sufficient conditions for the optimality of objective function in GNLP problem.
Dynamic programming: Kuhn –Tucker condition’s, Wolfe’s and Bcale’s method.
UNIT III: Deterministic inventory control models: Meaning & function role of inventory control, reason for carrying inventory, single item inventory control model with & without shortages.
Probabilistic inventory control models: Inventory control models without set up cost and with set up cost.
UNIT IV: Project management; PERT and CPM, Basic difference between PERT & CPM, Phases up project management PERT /CPM network component & precedence relationships, critical path analyses, projects scheduling with uncertain activity times, project time –cost trade-off.
Sequencing problem: Processing an jobs through two machines, three machines and through m-machines. Theory of games: Two- person zero –sum games,pure strategies (with saddle points) mixed strategies (without saddle point), algebraic method only.
TEXT / REFERENCE BOOKS:
1. H.A Taha, Operations Research, An introduction, PHI, 2008
2. H.M.Wanger, Principles of Operation Research PHI, Delhi, 1982
3. J.K.Sharma, Operations Research, Mcmillan India. Ltd,1990
4. S.D.Sharma, Operations Research, KedarnathRamnath publication,1985
5. P.K.Gupta and D.S Hira, Operations Research, S.Chand& Co.,1987
6. Pannerselvam, Operations Research; PHI, 2010
7. Harvey M Wanger , Principles of Operations Research; PHI, 2010
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronic gadgets including cellular phones are not allowed in the examination.
|MTOE657C: COST MANAGEMENT OF ENGINEERING PROJECTS (OPEN ELECTIVE) |
| M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
Course Outcomes:
Syllabus contents:
UNIT I: INTRODUCTION AND OVERVIEW
Chapter 1 Introduction, basic economic concepts, interest formulae, present worth, rate of return. Elements of financial accounting: depreciation, taxes and their impact in economic studies
Chapter 2 Cost concepts in decision making; elements of cost, relevant cost, overheads, differential cost, incremental cost and opportunity cost, objectives of a costing system, inventory valuation, creation of a data base for operational control, provision of data for decision making.
UNIT II: PROJECT
Chapter 3 Meaning, different types, why to manage, cost overrun centres, various stages of project execution, concept to commissioning. Project execution as conglomeration of technical and non technical activities. Detailed engineering activities, Pre project execution main clearances and documents project team: Role of each member.
Chapter 4 Importance Project site: Data required with significance. Project contracts.Types and contents. Project cost control. Bar charts and network diagram. Project commissioning: Mechanical and process. Project appraisal and selection, recent trends in project management
UNIT III: ECONOMIC ANALYSIS FOR ENGINEERING PROJECTS
Chapter 5 Cost behavior and profit planning, Marginal costing, distinction between marginal costing and absorption costing, Break even analysis, cost volume profit relationship, various decision making problems.
Standard costing and variance analysis, pricing strategies Pareto analysis, Target analysis, life cycle costing, Costing of service sector.
Chapter 6 just in time approach, material requirement planning, enterprise resource planning, Total Quality management and theory of constraints, Activity based cost management, Bench marking, Balanced score card, value chain analysis,
Budgetory control, Flexible budget, Performane budget, Zero based budget, Measurement of divisional profitability pricing decisions including transfer pricing.
UNIT IV: QUANTITATIVE TECHNIQUES FOR COST MANAGEMENT
Chapter 7 PERT CPM; Activity networks, basic PERT/CPM calculations, Planning and scheduling of activity networks, Assumptions in PERT modeling, time cost tradeoffs, PERT/ cost accounting, Scheduling with limited resources, Generalized activity networks GERT, Prospects of PERT/CPM
Chapter 8 Linear programming, Transportation problems, Assignment problems, Simulation, Learning curve theory.
TEXT / REFERENCE BOOKS:
|1 |Cost Accounting: A Managerial Emphasis |Charles T. Horngren, Srikant M. Datar, |Pearson Edu. |
| | |Madhav V. Rajan | |
|2 |Fundamentals of Financial Management |Prasanna Chandra |Tata McGraw Hill |
|3 |Quantitative Techniques in Management |N D Vohra |Tata McGraw Hill |
|4 |Foundation Engineering Handbook |Winterkorn, Hans |Chapman & Hall London. |
|5 |Principles and Practice of cost accounting |Ashish K Bhattacharya |A H Wheeler |
|6 |Principles of engineering economy |E L Grant et al. |John Wiley and Sons, New York. |
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronics gadgets including Cellular phones are not allowed in the examination.
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|MTOE659C: COMPOSITE MATERIALS (OPEN ELECTIVE) |
| M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
Course Outcomes:
Syllabus contents:
UNIT I: INTRODUCTION: Definition – Classification and characteristics of Composite materials. Advantages and application of composites.Functional requirements of reinforcement and matrix.Effect of reinforcement (size, shape, distribution, volume fraction) on overall composite performance.REINFORCEMENTS: Preparation-layup, curing, properties and applications of glass fibers, carbon fibers, Kevlar fibers and Boron fibers. Properties and applications of whiskers, particle reinforcements. Mechanical Behavior of composites: Rule of mixtures, Inverse rule of mixtures. Isostrain and Isostress conditions.
UNIT II: Manufacturing of Metal Matrix Composites: Casting – Solid Stat e diffusion technique, Cladding – Hot isostatic pressing.Properties and applications. Manufacturing of Ceramic Matrix Composites: Liquid Metal Infiltration – Liquid phase sintering. Manufacturing of Carbon – Carbon composites: Knitting, Braiding, Weaving. Properties and applications.
UNIT III: Manufacturing of Polymer Matrix Composites: Preparation of Moulding compounds and prepregs – hand layup method – Autoclave method – Filament winding method – Compression moulding – Reaction injection moulding. Properties and applications.
UNIT IV: Strength: Laminar Failure Criteria-strength ratio, maximum stress criteria, maximum strain criteria, interacting failure criteria, hygrothermal failure. Laminate first play failure-insight strength; Laminate strength-ply discount truncated maximum strain criterion; strength design using caplet plots;stress concentrations.
TEXT / REFERENCE BOOKS:
1. Material Science and Technology – Vol 13 – Composites by R.W.Ca hn – VCH, West Germany.
2. Materials Science and Engineering, An introduction. WD Callister, Jr., Adapted by R. Balasubramaniam, John Wiley & Sons, NY, Indian edition, 2007.
3. Hand Book of Composite Materials-ed-Lubin.
4. Composite Materials – K.K.Chawla.
5. Composite Materials Science and Applications – Deborah D.L. Chung.
6. Composite Materials Design and Applications – Danial Gay, Suong V. Hoa, and Stephen W. Tasi.
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronics gadgets including Cellular phones are not allowed in the examination.
|MTOE661C: WASTE TO ENERGY (OPEN ELECTIVE) |
| M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: |25Marks |
|3 |-- |3 | |Examination |: |75 Marks |
| | | | |Total |: |100 Marks |
| | | | |Duration of Examination |: |3 Hours |
Course Objectives:
To give an idea about different biomass and other solid waste materials as energy source and their processing and utilization for recovery of energy and other valuable products. A comprehensive knowledge of how wastes are utilized for recovery of value would be immensely useful for the students from all fields.
Course Outcomes:
In these days of energy crisis and environmental deterioration, students will understand the concept of energy by waste products. It is being used globally to generate electricity and provide industrial and domestic applications. Students will also enable to understand the environmental issues related to harnessing and utilization of various sources of energy and related environmental degradation.
Syllabus contents:
UNIT I: Sun as Source of Energy, Availability of Solar Energy, Nature of Solar Energy, Solar Energy & Environment. Various Methods of using solar energy –Photothermal, Photovoltaic, Photosynthesis, Present & Future Scope of Solar energy.
UNIT II: Introduction to Energy from Waste: Classification of waste as fuel – Agro based, Forest residue, Industrial waste, MSW
UNIT III: Biogas: Properties of biogas (Calorific value and composition) - Biogas plant technology and status - Bio energy system - Design and constructional features - Biomass resources and their classification, Biomass conversion processes, Thermo chemical conversion, Direct combustion, Types of biogas Plants, Applications.
UNIT IV: Thermo-chemical Conversion: Pyrolysis, Combustion, Gasification, Liquification. Bio-Chemical Conversion: Aerobic and Anaerobic conversion, Fermentation etc. Bio-fuels: Importance, Production and applications. Bio-fuels: Types of Bio-fuels, Production processes and technologies, Bio fuel applications, Ethanol as a fuel for I.C. engines, Relevance with Indian Economy.
TEXT / REFERENCE BOOKS:
1. Non Conventional Energy, Desai, Ashok V., Wiley Eastern Ltd., 1990.
2. Biogas Technology - A Practical Hand Book - Khandelwal, K. C. and Mahdi, S. S., Vol. I & II, Tata McGraw Hill Publishing Co. Ltd., 1983.
3. Food, Feed and Fuel from Biomass, Challal, D. S., IBH Publishing Co. Pvt. Ltd., 1991.
4. Biomass Conversion and Technology, C. Y. WereKo-Brobby and E. B. Hagan, John Wiley & Sons, 1996.
NOTE:
1. In the semester examination, the examiner will set 08 questions in all selecting two from each unit. The candidates will be required to attempt five questions in all selecting at least one from each unit. All questions will carry equal marks.
2. The students will be allowed to use non-programmable scientific calculator. However, sharing/exchange of calculator is prohibited in the examination.
3. Electronics gadgets including Cellular phones are not allowed in the examination.
|BT603C : DISSERTATION PHASE-I |
| M. Tech. Semester - III (Biotechnology) |
|L |P |Credits | |Class Work |: | 50 Marks |
|-- |20 |10 | |Examination |: |100 Marks |
| | | | |Total |: |150 Marks |
| | | | |Duration of Exam : | |- |
The objective of this course is to develop in students the capacity for analysis & judgment and the ability to carry out independent investigation in design/development through a dissertation work involving creativity, innovation and ingenuity. The work should start with comprehensive literature search and critical appreciation thereof so as to select a research problem and finalize the topic of dissertation.
Each student will carry out an independent dissertation under the supervision of a supervisor; in no case, more than two supervisors may be associated with one dissertation work. The first supervisor must be from the department, however, for interdisciplinary research work, the second supervisor may be from other department of the university/ outside university/industry. In the latter case, consent of the second supervisor with justification thereof needs to be submitted to the dissertation coordinator.
The Dissertation (Phase-I) involving literature survey and problem formulation along with data collection (if required) commences in 3rd semester &will be completed as Dissertation (Phase-II) in 4th semester. Each student will be required to present two seminar talks, first towards the beginning of the Dissertation (Phase-I) to present the scope of the work and to finalize the topic, and the second towards the end of the semester, presenting the progress report containing literature survey, partial results (if any) of the work carried out by him/her in the semester.The student will be required to submit one copy of spiral-bound progress report to the M.Tech. Coordinator.
Internal evaluation of Dissertation (Phase-I) will be done by following committee:
1. Chairperson / Head of Department / Nominee : Chairperson
2. M.Tech. Coordinator/Senior Faculty : Member-Secretary
3. Respective Dissertation Supervisor(s) : Member(s)
Final exam will be conducted by the internal examiner (M.Tech. Coordinator/ faculty nominated by Chairperson) & an external examiner to be appointed by Controller of Examinations from a panel of examiners submitted by the Dept.
For this course, M. Tech. coordinator will be assigned a load of 1 hour per week excluding his/ her own guiding load. Dissertation supervisor (guiding teacher) will be assigned a load of 1 hour per week for the first student and additional 1 hour per week (for their own department only) for the subsequent student(s) subject to a maximum load of 2 hours. Work load allocated for the joint supervision within the department will be treated as half for each supervisor.
|BT602C : DISSERTATION PHASE-II |
|M. Tech. Semester - IV (Biotechnology) |
|L |P |Credits | |Class Work |: |100 Marks |
|-- |32 |16 | |Examination |: |200 Marks |
| | | | |Total |: |300 Marks |
| | | | |Duration of Examination |: |- |
The Dissertation started in IIIrd Semester will be completed in IV Semester. During phase – II, student is expected to exert on design, development and testing of the proposed work as per the schedule. Accomplished results/contributions/innovations may be published/communicated in terms of research papers in reputed journals and review- focused conferences OR IP/Patents.
Phase – II deliverables: A dissertation report as per the specified format, developed system in the form of hardware and/or software, a record of continuous progress.
Phase – II evaluation: The Dissertation will be evaluated in the following manner
Internal Assessment
Internal Assessment (Class work evaluation) will be effected as per ordinance through interim report, presentation and discussion thereon by the following committee of three members.
Chairperson of Department : Chairperson
M.Tech. Coordinator/Sr. Faculty : Member Secretary
Respective dissertation Supervisor : Member
External Assessment
Final dissertation will be assessed by a panel of examiners consisting of the following
Chairperson of Department : Chairperson
Respective Supervisor(s) : Member(s)
External expert : To be appointed by the University
In case of unsatisfactory performance, committee may recommend for extension or repeating the work.
Supervisors will be assigned one hour teaching load per week.
NOTE:
1. M.Tech. Coordinator shall coordinate the work of dissertation exam.
2. The External Expert must be from the respective area of specialization. The Chairperson & M. Tech Co-ordinator with mutual consultation will divide the submitted dissertations into groups depending upon the area of specialization and will recommend the list of experts for each group separately to the V C for selecting the examiners with the note that an external expert should be assigned a maximum of FIVE dissertations for evaluation.
3. The student will be required to submit THREE copies of his/her report to the M.Tech. Co-ordinator for record and processing.
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