Chapter 8 - Toxicology: Poisons and Alcohol
Chapter 8 - Toxicology: Poisons and Alcohol
A History of poison…
Dates from before _________________ to the present day. Poisons have been used for many purposes: weapons, anti-venoms, and medicines. Poison has allowed much progress in branches of medicine, toxicology, and technology, among other sciences.
Toxins are poisons produced via some _________________________ in nature.
Venoms are biologic toxins that are _______________________________________to cause their effect
Other poisons are generally defined as substances which are _______________ through epithelial linings such as the______________________.
Toxicology: the study of the _________________________________of chemicals or physical agents on living organisms.
Types:
Environmental—air, water, soil
Consumer—foods, cosmetics, drugs
Medical, clinical, forensic
Forensic Toxicology
Postmortem—________________________________________
Criminal—motor vehicle _____________________________(MVA)
Workplace—________________________________
Sports—______________________________ (racehorses)
Environment—industrial, catastrophic, ____________________________
Toxic substances may:
Be a cause of ______________
Contribute to ________________
Cause _________________
Explain __________________
Aspects of Toxicity
_________________
The chemical or physical ___________________________of the substance
The ____________________________ into the body
Body weight and ___________________________________________of the victim, including age and sex
The ________________________ of exposure
The presence of ____________________________ in the body or in the dose
Lethal Dose
LD50: dose of substance that ______________ test population, usually within four hours
Expressed in milligrams of substance _________________________________ weight
Toxicity Classes
|LD50 (rat,oral) |Correlation to Ingestion by 150 lb Adult Human |Toxicity |
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