Name: _____________________________________________ Per ...



Name: _____________________________________________ Period: __________ Date: __________________________________

Codominance Worksheet: Blood Types

Human blood types are determined by genes that follow the CODOMINANCE pattern of inheritance; this means that both alleles are expressed (just like on a team with CO-CAPTAINS both captains get to express their opinions and both get to lead). There are two dominant alleles (IA or IB) and one recessive allele (i). The alleles determine the type of antigens on the surface of cells; antigens are markers found on the surface of cells. Read pages 324-325 in your textbook to complete the table below:

|Blood Type |Genotype(s) |Surface Molecule(s) |Can donate blood to: |Can receive blood from: |

|(Phenotype) | | | | |

| | | | | |

|B | | | | |

| | | | | |

|AB | | | | |

| | | | |(universal receiver) |

| | | | | |

|O | | | | |

| | | |(universal donor) | |

1. Write the genotype for each person based on the description:

a. Homozygous for the “B” allele ______

b. Heterozygous for the “A” allele ______

c. Type O ______

d. Type “A” and had a type “O” parent ______

e. Type “AB” ______

f. Blood can be donated to anybody ______

g. Can only get blood from a type “O” donor ______

2. Pretend that SpongeBob is homozygous for the type B allele, and SpongeSusie is type “O.” What are all the possible blood types of their baby? Use a Punnett Square to support your answer.

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

3. Draw a Punnett square showing all the possible blood types for the offspring produced by a type “O” mother and an a Type “AB” father

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

4. Mrs. Squidward is type “A” and Mr. Squidward is type “O.” They have three children named Squishy, Squirt, and Emmanuel Lewis. Squishy is type “O,” Squirt is type “A,” and Emmanuel Lewis is type “AB.” They think one of their kids was switched at birth. Based on this information:

a. Mr. Squidward can only have the genotype _________________.

b. Mrs. Squidward must have the genotype ___________ because _________________ has blood type __________.

c. Draw a Punnett Square for the possible offspring that Mrs. and Mr. Squidward can produce.

d. Which child must have been switched at birth? Explain your answer.

5. Two parents think their baby was switched at the hospital. It’s 1968, so DNA fingerprinting technology does not exist yet. The mother has blood type “O,” the father has blood type “AB,” and the baby has blood type “B.”

a. Mother’s genotype: _______

b. Father’s genotype: _______

c. Genotype(s) of all kids: _______________________________________________________

d. Punnett square showing all possible genotypes for children produced by this couple:

e.

f. Was the baby switched? Explain your answer.

6. Two other parents think their baby was switched at the hospital. The mother is homozygous type “A,” the father is heterozygous type “B,” and the baby has blood type “AB.”

a. Mother’s genotype: _______

b. Father’s genotype: _______

c. Baby genotype possibilities for this couple: ____________ or ___________

d. Punnett square showing all the possible genotypes for children produced by this couple:

e. Was the baby switched? Explain your answer.

7. Cross a purebred Type A woman with a hybrid Type B man.

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

8. Lisa is a universal donor. Her father Homer is has Type A blood and her mother Marge has Type B blood.

a. What is Homer’s genotype?______________ What is Marge’s genotype? __________________

b. Draw a Punnett Square to support your answers for the parental genotypes.

c. What are the possible genotypes for Bart and Maggie? _______________________________

Name: _____________________________________________ Period: __________ Date: __________________________________

Codominance Worksheet: Blood Types (HONORS)

Human blood types are determined by genes that follow the CODOMINANCE pattern of inheritance; this means that both alleles are expressed (just like on a team with CO-CAPTAINS both captains get to express their opinions and both get to lead). There are two dominant alleles (IA or IB) and one recessive allele (i). The alleles determine the type of antigens on the surface of cells; antigens are markers found on the surface of cells. When blood with a different surface markers are introduced to a person’s circulatory system the person’s immune system will produce antibodies in an effort to attack the foreign cells. Read pages 324-325 in your textbook to complete the table below:

|Blood Type |Genotype(s) |Surface Molecule(s) |Immune System will attack |Can donate blood to: |Can receive blood from: |

|(Phenotype) | | |which surface molecule(s)? | | |

| | | | | | |

|B | | | | | |

| | | | | | |

|AB | | | | | |

| | | | | |(universal receiver) |

| | | | | | |

|O | | | | | |

| | | | |(universal donor) | |

1. Write the genotype for each person based on the description:

a. Homozygous for the “B” allele ______

b. Heterozygous for the “A” allele ______

c. Type O ______

d. Type “A” and had a type “O” parent ______

e. Blood can be donated to anybody ______

f. Can only get blood from a type “O” donor ______

2. Pretend that SpongeBob is homozygous for the type B allele, and SpongeSusie is type “O.” What are all the possible blood types of their baby? Use a Punnett Square to support your answer.

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

3. Draw a Punnett square showing all the possible blood types for the offspring produced by a type “O” mother and an a Type “AB” father.

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

4. Mrs. Squidward is type “A” and Mr. Squidward is type “O.” They have three children named Squishy, Squirt, and Emmanuel Lewis. Squishy is type “O,” Squirt is type “A,” and Emmanuel Lewis is type “AB.” They think one of their kids was switched at birth. Based on this information:

a. Mr. Squidward can only have the genotype _________________.

b. Mrs. Squidward must have the genotype ___________ because _________________ has blood type __________.

c. Draw a Punnett Square for the possible offspring that Mrs. and Mr. Squidward can produce.

d. Which child must have been switched at birth? Explain your answer.

5. Two parents think their baby was switched at the hospital. It’s 1968, so DNA fingerprinting technology does not exist yet. The mother has blood type “O,” the father has blood type “AB,” and the baby has blood type “B.”

a. Mother’s genotype: _______

b. Father’s genotype: _______

c. Genotype(s) of all kids: _______________________________________________________

d. Punnett square showing all possible genotypes for children produced by this couple:

e.

f. Was the baby switched? Explain your answer.

6. Two other parents think their baby was switched at the hospital. The mother is homozygous type “A,” the father is heterozygous type “B,” and the baby has blood type “AB.”

a. Mother’s genotype: _______

b. Father’s genotype: _______

c. Baby genotype possibilities for this couple: ____________ or ___________

d. Punnett square showing all the possible genotypes for children produced by this couple:

e. Was the baby switched? Explain your answer.

7. Cross a purebred Type A woman with a hybrid Type B man.

Parental Genotypes _____________ X _____________

Offspring Genotypic Ratio:

Offspring Phenotypic Ratio:

8. Lisa is a universal donor. Her father Homer is has Type A blood and her mother Marge has Type B blood.

a. What is Homer’s genotype?______________ What is Marge’s genotype? __________________

b. Draw a Punnett Square to support your answers for the parental genotypes.

c. What are the possible genotypes for Bart and Maggie? ___________________

9. In addition to the ones that determine blood type, there are other antigens on the surface of blood cells such as the D antigen (also known as Rh factors). Individuals who have the Rh factor are considered positive, individuals who do not have the Rh factor are considered negative. If a Rh negative woman is pregnant with fetus that is Rh positive the woman’s body will produce antibodies that will start attacking the cells of the fetus. Fortunately, doctors can give the woman medicine to prevent this from happening. Construct a pedigree for the following family on a separate sheet of paper, staple it to this worksheet. Use “D” and “d” to represent the alleles,

Kelly is Rh positive. Her parents, Daniel and Sue, are also Rh positive. While pregnant with Kelly’s dad, grandma almost lost the baby due to incompatible blood types. Kelly’s grandma on mom’s side of the family did not have difficulties while pregnant with Sue. Both of Kelly’s grandfathers are Rh positive. Kelly has two siblings: George and Cindy. George is Rh positive and Cindy is Rh negative. Cindy marries Jonah who is Rh positive. They have three children: Bobby, Katniss, and Jack; the boys are both Rh positive and Katniss is Rh negative.

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