CURRICULUM VITAE - Extrapolate . . . LLC



NAME: KATHERINE FREEMAN, Dr.P.H.

CONTACT: EXTRAPOLATE . . . LLC

Mobile: (203) 273—7828

Email: kfreeman@

Website:

EDUCATION

|S.U.N.Y. Binghamton, N.Y. |B.A. (Mathematics) | |

| |

|University of Massachusetts, Amherst |M.S. (Biostatistics) | |

|Columbia University School of Public Health | | |

|New York, N.Y. |Dr.P.H. (Biostatistics) | |

POST-DOCTORAL TRAINING

|Massachusetts Institute of Technology Cambridge, |Sloan School, Certificate in Business Management | |

|Massachusetts | | |

|Institute of Child Health, University College London |Department of Epidemiology and Biostatistics, Centre for Evidence-Based | |

| |Child Health: Sabbatical | |

HIGHEST ACADEMIC APPOINTMENT:

Professor, Department of Epidemiology and Population Health (through 2012)

Department of Epidemiology and Population Health

Division of Biostatistics

Albert Einstein College of Medicine, Bronx, N.Y.

PROFESSIONAL EMPLOYMENT

Montefiore Medical Center (MMC) Appointments—25 years of service

|Director of Biostatistics |1992-2009 |

|Montefiore Medical Center, Bronx, N.Y. | |

GRANT SUPPORT

|Principal Investigator of Subcontract NICHD 1R21HD069628-01 (Pulido) |2012-2014 |

|Safe Touches: A Rigorous Evaluation of a Sexual Abuse Prevention Program for Children (PRO, HEOR) | |

|Co-Investigator NIH R01 (Wylie-Rosett) Comprehensive Approach to Family Weight Management (PRO) |2008-2013 |

|Co-Investigator of RCT NCMHD R01 (Strelnick) Research Center of Excellence Bronx CREED Health Disparities |2007-2012 |

|Co-Investigator NICHD 1R01HD053693-01A2 (Arens) Pathophysiology of OSAS in obese children 8-17 years old (PRO) |2008-2012 |

|Co-Investigator 1R01 HD049763-01 (Bonuck) |2007-2012 |

|Boosting Breastfeeding in Low-Income, Multiethnic Women: A Primary Care-Based RCT | |

|Co-Investigator NIH R21 HL091241-01 (Bonuck) Sleep Disordered Breathing and Growth in Children: A Longitudinal Cohort Study |2008-2010 |

|(PRO) | |

|Co-Investigator NIH R03 (Feldman) Racial/ethnic differences in symptom perception in childhood asthma | |

| |2008-2010 |

|Co-Investigator NICHD 1R21HD052721-01A2 (Isasi) The role of self-control on adolescents’ diet and exercise behavior (PRO) |2007-2009 |

|Principal Investigator of Subcontract. 1 R03 EY015287-01 (Gilbert) (PRO) |2004- 2006 |

|National Eye Institute. Statistical Analysis: Retinochoroiditis in Congenital Toxoplasmosis | |

|Co-Investigator. Robert Wood Johnson Foundation (Kennedy) Clinical Trial of Telephone Intervention for Depression Medication|2004- 2006 |

|Adherence and Healthcare Cost Containment | |

|Senior Statistician. NIH/NIAID 1P30AI051519 (Goldstein) |2003- 2008 |

|Center for AIDS Research | |

|Senior Statistician NYS DOH AIDS Institute (Zingman) Community-Based HIV Primary Care and Prevention Services Grant: |2003- 2008 |

|Development of a HIV-HCV Program at the Montefiore Infectious Diseases (ID) Clinic. | |

|Core Director Shared Resources, Bronx CREED. 1 P60 MD000514-01 (Strelnick) |2003- 2007 |

|National Center on Minority Health and Health Disparities (PRO) | |

|Co-Investigator. AHRQ grant HS 10900 (Bonuck) |2000- 2004 |

|Economic Impact of Breast-Feeding Promotion Intervention (PRO) | |

|Co-Investigator. “Economic Impact of Breast-Feeding Promotion Intervention” Agency for Healthcare Research and Quality Karen|2000- 2004 |

|Bonuck, Ph.D. Principal Investigator (PRO) | |

|Co-Investigator. 1K-30HL04110-01(Marantz) National Heart Lung and Blood Institute |1999- 2004 |

|Clinical Research Training Program | |

|Principal Investigator. Clinical and Biostatistical Core “Studies of Papillomas from the Upper Respiratory Tract” NIDCD |1999- 2004 |

|DC00203-15A1, Bettie Steinberg, Ph.D. Principal Investigator | |

|Co-Investigator. “Optimization of PDT Using meso-Tetra Hydroxyphenyl Chlorin” NIDCD |1999- 2004 |

|DC04039-01, Mark Shikowitz, M.D. Principal Investigator | |

|Co-Investigator, Member Steering Committee, Member Admissions Committee, Director of Biostatistics Curriculum, “Clinical |1999- 2004 |

|Research Training Program”, NHLBI, Paul Marantz, M.D., Principal Investigator | |

|Co-Principal Investigator. “Impact of Time and SCBA Tank Utilization on Injury Prevention in Fire Fighters.” NIOSH G |1998- 2001 |

|1R010H03802-01 David Prezant, M.D. Principal Investigator | |

|Principal Investigator. “Epidemiology of Family Centered Stress Among those with a Child with a Brain Tumor.” Two awards |1996- 1999 |

|from Children’s Brain Tumor Foundation. (PRO) | |

|Principal Investigator of Subcontract. “Studies of Papillomas from the Upper Respiratory Tract.” NIDCD #2P50DC0023-12A2. |1995- 1999 |

|Bettie Steinberg, Ph.D. Principal Investigator. | |

|Principal Statistician. “Controlled Treatment Trial of Patients with Lyme Disease.” Award # RO1 AR41508 from the National |1992- 1997 |

|Institute of Musculoskeletal and Skin Diseases. Robert Nadelman, M.D. Principal Investigator. | |

|Principal Statistician. “Incidence of Human Granulocytic Ehrichiosis and Babesiosis After Ixodes Scapularis Tick Bites in |1990- 1995 |

|Westchester County, NY.” Award # U50/CCU 210286 Centers for Disease Control and Prevention. Robert Nadelman, M.D. Principal| |

|Investigator. | |

|Co-Investigator. “Pediatric and Adult AIDS Clinical Trials Group.” NIAID # 1 UO1 AI27533-01A1, Arye Rubinstein, M.D., Ruy |1989- 1994 |

|Soeiro, M.D. Principal Investigators. | |

DATA SAFETY AND MONITORING BOARDS (NIH)

|Chairperson: Phase I study of anakinra in SSNHL corticosteroid-resistant subjects (Unfunded by NIDCD) |2014- |

|Chairperson: NIH (NIDCD) An open-label study of the effects of gevokizumab in corticosteroid-resistant subjects with |2013- |

|autoimmune inner ear disease | |

|Chairperson: NIH (NIDCD) Phase I study of anakinra in corticosteroid-resistant subjects |2011-2014 |

|Chairperson: NIH (NIDDK): Longitudinal study of Polycystic Kidney Disease (CRISP II) |2006- 2011 |

|NIH (NIDDK) Funded Multicenter Study to develop markers of progression. “Consortium for Radiologic Imaging Studies of |2000- 2005 |

|Polycystic Kidney Disease (CRISP)” | |

|NIH (NIDDK) Funded Multicenter Clinical Trial. “RASS” Michael Mauer, M.D. Principal Investigator. |1999- 2004 |

|NIH (NIDDK) Funded Multicenter Clinical Trial. “HUS Synsorb Pk.” Howard Trachtman, |1997- 2003 |

|M.D. Principal Investigator. | |

DATA SAFETY AND MONITORING BOARDS (OTHER THAN NIH)

|Chairperson: (LIJ) A phase I & II open-label study of the effects of anakinra in corticosteroid-resistant subjects with |2014- |

|sudden sensorineural hearing loss (SSNHL) | |

Chairperson: Randomized Controlled Trial of Radiofrequency Ablation for the 2009-2010

Treatment of Paroxysmal Atrial Fibrillation Using the Bard High Density Mesh Ablation

System (MAGELLAN) Bard Electrophysiology

PROCHYMAL TM (ex vivo Cultured Adult Human Mesenchymal Stem Cells) for the 2008-2011

Treatment of Recently Diagnosed Type 1 Diabetes Mellitus (T1DM) Osiris Therapeutics

|Registry of high surgical risk patients with extracranial carotid artery stenosis using Bard VIVEXX Carotid Stent and |2005-2009 |

|Emboshield Bare Wire Exchange Embolic Protection System | |

|Clinical trial of aqueous oxygen therapy for 90 minutes v. control therapy in anterior acute myocardial infarction patients |2005- 2008 |

|following PCI/stent placement (AMIHOT II ) Therox | |

|Determining efficacy IV Ketorolac as beneficial agent in patients with sickle cell vaso-occlusive crisis treated with |2004- 2005 |

|morphine or morphine equivalent (DSMC at AECOM) | |

|Clinical trial of Daptomycin Compared to Conventional Therapy In the Treatment of Subjects With Infective Endocarditis or |2002- 2005 |

|Bacteremia Due to Staphylococcus aureus, Cubist. | |

|Single arm stent trial to treat Infra-renal abdominal aortic aneurysms and aorto-iliac aneurysms (VANGUARD); Boston |2000- 2005 |

|Scientific Corporation | |

|Registry of High Risk Patients Who Receive Wallstent and Percusurg System (SHELTER) for Carotid Artery Disease. Boston |2000- 2002 |

|Scientific Corporation. | |

|Single arm stent trial to treat moderate to high-risk surgical patients with lesions in the internal carotid artery |1999- 2003 |

|(ARCHER); Guidant Corporation | |

NIH REVIEWS

|NIH (NIDDK) Member of Ad Hoc Special Emphasis Panel |2005 |

|NIH F16 T20L Special Emphasis Panel |2007-2008 |

EDITORIAL BOARD AND JOURNAL REVIEWS (1995-present)

Statistical/Epidemiologic Reviewer : American Journal of Neuroradiology 2014-

Editorial Board Member: The Cleft Palate Journal, Journal of Neuro-Ophthalmology

Ad Hoc Reviewer: Diabetes Care, Journal of Immigrant and Minority Health, Pediatrics

SELECTED RESEARCH CONSULTING ACTIVITIES

|University of Florida College of Dentistry |2015- |

|Swiss Healthcare Solutions Medical device company/Yale: analysis of cohort study |2014- |

|PROPEL llc Orthodontic Medical device company: analysis of cohort study |2014 |

|Beth Israel Medical Center, NY: statistical consultation for palliative care study |2013- |

|New York Academy of Medicine: statistical consultation of community interventions |2012- |

|Ion Channel: analyze data from NIH SBIR regarding bladder function |2012- |

|Boehringer Ingleheim: revisions of EMA survey proposal (HEOR) |2012 |

|Molnynlcke: economic analysis of treatment for burn wounds (HEOR) |2012 |

|Columbia University College of Dental Medicine: NIH grant application for behavioral |2012 |

|intervention for pediatric compliance | |

|University of South Florida: wrote NIH grant application for behavioral intervention for |2012 |

|patients with post traumatic stress disorder secondary to sexual abuse | |

|Montefiore Medical Center Department of Dentistry: mentor residents/fellows/faculty |2011- |

|University of Colorado NIH funded RCT: analysis of data and design of new grant |2012- |

|application for LSVT in early Parkinson patients | |

|Medical University of South Carolina DOD grant: design/analysis of nosocomial infections |2011-2013 |

|in multicenter trial with copperized furnishings in Medical ICU | |

|New York Society for the Prevention of Cruelty to Children: wrote NIH grant application |2010- |

|for cluster RCT and statistical analyses (PRO, HEOR) | |

|Ortho McNeil Janssen: HEOR Antibiotic Intervention Outcomes for Complicated Skin and |2009-2011 |

|Soft Tissue Nosocomial Infections in Hospitalized Patients (HEOR) | |

|Organogenesis & Boston Biomedical Associates: HEOR advanced biologics (HEOR) |2008-2009 |

|Hudson Health Plan: statistical models for Medicaid and Child Health Plus health |2000- 2006 |

|maintenance organization to distribute state funds based on performance (HEOR) | |

|Expert statistics/epidemiology opinion for systematic review regarding diet drugs in product |2000- 2002 |

|liability litigation; Patterson, Belknap, Webb & Tyler LLP | |

|Health Network America: statistical models for physician profiling of providers of U.S. |1999- 2000 |

|Panama Canal employee descendants using claims data | |

|Principal Statistician. “A Controlled Study to Determine Synergy Between AZT and TJ-9 in |1995- 1996 |

|the Modulation of HIV in HIV Positive Individuals with CD4 150-400.” Tsumura & Co. | |

|Principal Statistician. “Extension Phase of Wobenzym v. Placebo Clinical Trial for the |1993- 1994 |

|Management of HIV Positive Patients with CD4 250-400.” MUCOS Pharma. | |

|Principal Statistician. “Pentoxyfylline in Persons with HIV Infection; A Double Blind, |1993 |

|Placebo Controlled Study.” Community Research Initiative. | |

|Principal Statistician. “Histology, Gynecology and Immunology Findings in HIV+ Women.” | |

|Bronx-Lebanon Hospital Center. |1992- 1993 |

|Principal Statistician. “Evaluation of Wobenzym v. Placebo as a Therapy for the |1992- 1993 |

|Management of HIV Positive Patients with CD4 250-400.” MUCOS Pharma. | |

|Principal Statistician. “Use of Aerosolized of Pentamidine and Evaluation of Pulmonary |1990- 1991 |

|Function Tests in HIV Patients.” Community Research Initiative. | |

|Principal Statistician. “Methionine Enkephalin Treatment of ARC.” TNI Pharma, Inc. |1990- 1992 |

| | |

PROFESSIONAL SOCIETIES: American Statistical Association, Society of Clinical Trials, International Society for Pharmacoeconomics and Outcomes Research

PUBLICATIONS :

ORIGINAL COMMUNICATIONS IN REVIEWED JOURNALS:

1. Gocka E.F., Conner L.E., Freeman K., & Wilson D. (1973) Alcoholism as a predictive index of elapsed time between grand mal seizures. J. Clin. Psychol. 29:306-312.

2. Barnett H.L., Edelmann C.M., Jr, Greifer I., Spitzer A., Freeman K., & ISKDC. (1978) Nephrotic Syndrome in Children: Prediction of Histopathology from Clinical and Laboratory Characteristics at Time of Diagnosis. A Report of the International Study of Kidney Disease in Children. Kidney Int. 13:159-165.

3. Eviatar L., Miranda S., Eviatar A., Freeman K., & Borkowski M. (1979) The Development of Nystagmic Response to Vestibular Stimulation in Infants. Ann. Neurol. 5:508-514.

4. Barnett H.L., Edelmann C.M., Jr, Greifer I., Spitzer A., Freeman K., & ISKDC. (1981) Nephrotic Syndrome in Children: A Report of the International Study of Kidney Disease in Children. J. Pediatr. 95:239-243.

5. Barnett H.L., Edelmann C.M., Jr., Greifer I., Spitzer A., Freeman K., & ISKDC. (1981) Primary Nephrotic Syndrome in Children: Clinical Significance of Histopathologic Variants of Minimal Change and of Diffuse Mesangial Hypercellularity. A Report of the International Study of Kidney Disease in Children. Kidney Int. 20:765-771.

6. Condit D., Freeman K., & Brodman R. (1987) Hyperamylasemia in Cardiac Surgical Patients Receiving Hydroxyethyl Starch. J. Crit. Care 2:36-38.

7. Jackson, B., Freeman, K., & Chagares, R. (1987) The Effects of the Clinitron Bed on Pressure Ulcers. J. Nurs. Adm. 17:11-15.

8. Ascer E., White S.A., Veith F.J., Morin L., Freeman K., & Gupta S.K. (1987) Outflow Resistance Measurement During Infraninguinal Arterial Reconstructions: Reliable Predictor of Limb Salvage. Am. J. Surg. 154:185-188.

9. Klein R.S., Phalen J.A., Freeman K., Schable C., Friedland G.H., Trieger N., & Steigbigel N.H. (1988) Low Occupational Risk of Human Immunodeficiency Virus Infection Among Dental Professionals. N. Engl. J. Med. 318:86-90.

10. Link R., Feingold A., Charap M., Freeman K., & Shelov S. (1988) Concerns of Medical and Pediatric House Officers about Acquiring AIDS from their Patients. Am. J. Public Health 78:455-459.

11. Jackson B., Chagares R., Nee N., & Freeman K. (1988) The Effects of a Therapeutic Bed on Pressure Ulcers: An Experimental Study. J. Enterostomy Therapy 15:220-226.

12. Klein R.S., Selwyn P.A., Maude D., Pollard C., Freeman K., & Schiffman G. (1989) Response to Pneumococcal Vaccine Among Asymptomatic Heterosexual Partners of Persons with AIDS and Intravenous Drug Users Infected with Human Immunodeficiency Virus. J. Infect. Dis. 160:826-831.

13. Green S.B., Ellenberg S.S., Finkelstein D., Forsythe A., Freedman L., Freeman K., Lefkopoulou M., Schoenfeld D., & Smith R. (1990) Issues in the Design of Clinical Trials for AIDS. Control. Clin. Trials 11:80-87.

14. Friedland G.H., Saltzman B., Vileno J., Freeman K., Schrager L.K., & Klein R.S. (1991) Survival Differences in Patients with the Acquired Immunodeficiency Syndrome. J. Acquir. Immune Defic. Syndr. 4:144-153.

15. Goldstein J.D., Dickson D.W., Moser F.G., Hirschfeld A.D., Freeman K., Llena J.F., Kaplan B., & Davis L. (1991) Primary Central Nervous System Lymphoma in Acquired Immune Deficiency Syndrome. Cancer 67:2756-2765.

16. Hegarty A.M., Lipton R.B., Merriam A.E., & Freeman K. (1991) Cocaine as a Risk Factor for Acute Dystonic Reactions. Neurology 41:1670-1672.

17. Klein R.S., Freeman K., Taylor P.E., & Stevens C.E. (1991) Occupational Risk for Hepatitis C Virus Infection Among New York City Dentists. Lancet 338:1539-1542.

18. Prezant D.J., Valentine D.E., Gentry E.I., Richner B., Cahill J., & Freeman K. (1993) Effects of Short-Term and Long-Term Androgen Treatment on the Diaphragm in Male and Female Rats. J. Appl. Physiol. 75:1140-1149.

19. Haramati N., Staron R.B., Mazel-Sperling K., Freeman K., Nickoloff E.L., Barax C., & Feldman F. (1994) CT Scans Through Metal Scanning Technique Versus Hardware Composition. Comput. Med. Imaging Graph. 18:429-434.

20. Dallam L., Smyth C., Jackson B., Krinsky R., O’Dell C., Rooney J., Badillo C., Amella E., Ferrara L., & Freeman K. (1995) Pressure Ulcer Pain: Assessment and Quantification. J. Wound Ostomy Continence Nurs. 22:211-218.

21. Suss A.L.,Tinkelman B., Freeman K., & Friedman S.B. (1996) School Attendance, Health-Risk Behaviors and Self-Esteem in Adolescents Applying for Working Papers. Bull. N Y Acad. Med. 73:255-265.

22. Jacobs L.G., Skidmore E.A., Freeman K., Lipshultz D., & Fox N. (1996) Oral Fluconizole Compared with Bladder Irrigation with Amphotericin B for Treatment of Fungal Urinary Tract Infections in Elderly Patients. Clin. Infect. Dis. 22:30-35.

23. Rubin D.M., Eisig S., Freeman K., & Kraut R.A. (1997) Effect of supplemental gases on end-tidal CO2 and oxygen saturation in patients undergoing fentanyl and midazolam outpatient sedation. Anesth. Prog. 44:1-4.

24. Strauch B., Lang A., Ferder M., Keyes-Ford M., Freeman K., & Newstein D. (1997) The Ten Test. Plast. Reconstr. Surg. 99:1074-1078.

25. Ryan R., Walker G., Freeman K., & Cisneros G.J. (1997) The Effects of Ion Implantation on Rate of Tooth Movement: An in vitro model. Am. J. Orthod. Dentofacial Orthop. 112:64-68.

26. Evanko A.M., Freeman K., & Cisneros G.J. (1997) Mesh Diagram Analysis: Developing a Norm for Puerto Rican Americans. Angle Orthod. 67:381-388.

27. Hamerman D., Freeman K., & Stanley E.R. (1998) Colony Stimulating Factor-1 in Synovial Fluids From Osteoarthritic and Injured Knees. Letter Ann. Rheum. Dis. 57:260-261.

28. Shikowitz M., Abramson A., Freeman K., Steinberg B., & Nouri M. (1998) Efficacy of DHE Photodynamic Therapy for Respiratory Papillomatosis: Immediate and Long Term Results. Laryngoscope 108:962-967.

29. Rahal J.J., Urban C., Horn D., Freeman K., Segal-Maurer S., Maurer J., Mariano N., Marks S., Burns J., Dominick D., & Lim M. (1998) Hospital-wide Withdrawal of Cephalosporin Use for Control of Total Resistance to Cephalosporins in Klebsiella. JAMA. 280:1233-1237.

30. Del Rowe J., Bello J., Mitnick R., Sood B., Philippi C., Moran J., Freeman K., Mendez F., & Bases R. (1998) Accelerated Regression of Brain Metastases in Patients Receiving Whole Brain Radiation and the Topoisomerase II inhibitor, Lucanthone. Int. J. Radiat. Oncol. Biol. Phys. 42:1-5.

31. Bartling R., Freeman K., & Kraut R.A. (1999) The incidence of altered sensation of the mental nerve after mandibular implant placement. J. Oral Maxillofac. Surg. 57:1408-1412.

32. Gourevitch M., Hartel D., Tenore P., Freeman K., Marion I., Hecht J., & Lowinson J. (1999) Three Oral Formulations of Methadone: A clinical and pharmacodynamic comparison. J. Subst. Abuse Treat. 17:237-241.

33. Potters L. and Freeman K. (1999) Prostatectomy, External Beam Radiation Therapy, or Brachytherapy for Localized Prostate Cancer. authors’ reply JAMA. 281:1584.

34. Mankad B., Cisneros G.J., Freeman K., & Eisig S.B. (1999) Prediction accuracy of soft tissue profile in orthognathic surgery. Int. J. Adult Orthodon. Orthognath. Surg. 14:19-26.

35. Berger A.R., Schaumburg H.H., Gourevitch M.N., Freeman K., Herskovitz S., & Arezzo J.C. (1999) Prevalence of peripheral neuropathy in injection drug users. Neurology 53:592-597.

36. Cha C.M., Potters L., Ashley R., Freeman K., Wang X.H., Waldbaum R., & Leibel S. (1999) Isotope selection for patients undergoing prostate brachytherapy. Int. J. Radiat. Oncol. Biol. Phys. 45:391-395.

37. Potters L., Cha C.M., Ashley R., Freeman K., Waldbaum R., Wang X.H., & Leibel S. (2000) The Role of External Beam Irradiation in Patients Undergoing Prostate Brachytherapy. Urol. Oncol. 5:112-7.

38. Freeman K., O’Dell C., & Meola C. (2000) Issues in Families of Children with Brain Tumors. Oncol. Nurs. Forum 27:843-848.

39. Prezant D., Freeman K., Kelly K., Malley K., Karwa M., McLaughlin M., Hirschhorn R., & Brown A. (2000) Impact of a Design Modification in Modern Firefighting Uniforms on Burn Prevention Outcomes in New York City Firefighters. J. Occup. Environ. Med. 42:827-834.

40. Nadelman R.B., Nowakowski J., Fish D., Falco R., Freeman K., McKenna D., Welch P., Marcus R., Aguero-Rosenfeld M., Dennis D.T., & Wormser G.P. (2001) Single Dose Doxycycline Prophylaxis for Prevention of Lyme Disease after an Ixodes scapularis Tick Bite: A Randomized Double-blinded Placebo-controlled Study. N. Engl. J. Med. 345:79-84.

41. Freeman K., Smyth C., Dallam L., & Jackson B. (2001) Pain Measurement Scales: A Comparison of the Visual Analogue and Faces Rating Scales Used in Measuring Pressure Ulcer Pain. J. Wound Ostomy Continence Nurs. 28:290-296.

42. Freeman K., O’Dell C., & Meola C. (2001) Focus Group Methodology for Parents, Siblings and Children Diagnosed with a Brain or Spinal Cord Tumor. J. Pediatr. Oncol. Nurs. 18(6):276-286.

43. Badner V.M., Karasz A., Simoyan O.M., & Freeman K. (2001) Assessment and Service Utilization Study of Dental Care for HIV-infected Persons in New York City. Report for the City of New York, Office of the Mayor.

44. Bonuck K., Arno P.S., Memmott M.M., Freeman K., Gold M., & McKee D. (2002) Breast-feeding promotion interventions: good public health and economic sense. J. Perinatol. 22:78-81.

45. Abdalla A., Sheesha A.A., Shokeir M., el-Agrody O., el-Regal M.E., Abdel-Khalik M.K., Freeman K., Boneberg A., & A-Kader H.H. (2002) Serum intercellular adhesion molecule-I in children with chronic liver disease: relationship to disease activity. Dig. Dis. Sci. 47:1206-1208.

46. Smith R.E., Badner V.M., Morse D.E., & Freeman K. (2002) Maternal risk indicators for childhood caries in an inner city population. Community Dent. Oral Epidemiol. 30:176-181.

47. Haut S.R., Swick C., Freeman K., & Spencer S. (2002) Seizure clustering during epilepsy monitoring. Epilepsia 43:711-715.

48. Silverman R.A., Osborn H., Runge J., Gallagher E.J., Chiang W., Feldman J., Gaeta T., Freeman K., Levin B., Mancherje N., & Scharf S. (2002) Acute Asthma/Magnesium Study Group. IV magnesium sulfate in treatment of acute severe asthma: a multicenter randomized controlled trial. Chest. 122:396-98.

49. Smith M.A., Gertler T., & Freeman K. (2003) Medical students' perceptions of their housestaffs' ability to teach physical examination skills. Acad. Med. 78(1):80-83.

50. Freeman K., O’Dell C., & Meola C. (2003) Childhood brain tumors: Children's and siblings' concerns regarding the diagnosis and phase of illness. J. Pediatr. Oncol. Nurs. 20(3):133-140.

51. Shaw P.M., Veith F.J., Lipsitz E.C., Ohki T., Suggs W.D., Mehta M., Freeman K., McKay J., Berdejo G.L., Wain R.A., & Gargiulo III N.J. (2003) Open aneurysm repair at an endovascular center: Value of a modified retroperitoneal approach in patients at high risk with difficult aneurysms. J. Vasc. Surg. 38:504-510.

52. Freeman K., O’Dell C., & Meola C. (2004) Childhood Brain Tumors: Parental Concerns and Stressors by Phase of Illness. J. Pediatr. Oncol. Nurs. 21:87-96.

53. Huang J.M., Anastos K., Robison E., Shi R., Freeman K., Strickler H., & Steinberg J.J. (2004) Evaluation of DNA adduction of AZT in peripheral blood leukocytes of HIV-infected individuals by (32)P-post-labeling thin-layer chromatography: a feasibility study. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 810:1-6.

54. Freeman K., Oakley L., Pollak A., Buffolano W., Petersen E., Semprini A.E., Salt A., & Gilbert R. for the European Multicentre Study on Congenital Toxoplasmosis. (2005) Association between congenital toxoplasmosis and preterm birth, low birthweight and small for gestational age birth. BJOG. 112:31-37.

55. Shikowitz M.J., Abramson A.L., Steinberg B.M., DeVoti J., Bonagura V.R., Mullooly V., Nouri M., Ronn A.M., Inglis A., McClay J., & Freeman K. (2005) Clinical trial of photodynamic therapy with meso-tetra (hydroxyphenyl) chlorin for respiratory papillomatosis. Arch. Otolaryngol. Head Neck Surg. 131:99-105.

56. Salt A., Freeman K., Prusa A., Malm G., Ferret N., Buffalono W., Schmidt D., Tan H.K., & Gilbert R.E. for the European Multicentre Study on Congenital Toxoplasmosis. (2005) Determinants of response to a parent questionnaire about development and behaviour in 3 year olds: European multicentre study of congenital toxoplasmosis. BMC Pediatr. 5:21.

57. Freeman K., Salt A., Prusa A., Malm G., Ferret N., Buffalono W., Schmidt D., Tan H.K., & Gilbert R.E. for the European Multicentre Study on Congenital Toxoplasmosis. (2005) Association between congenital toxoplasmosis and parent-reported developmental outcomes, concerns, & impairments, in 3 year old children. BMC Pediatr. 5:23.

58. Ettinger L.M., Freeman K., Dimartino-Nardi J.R., & Flynn J.T. (2005) Microalbuminuria and abnormal ambulatory blood pressure in adolescents with type 2 diabetes mellitus. J. Pediatr. 147:67-73.

59. Bonuck K.A., Freeman K., & Trombley M. (2005) Country of origin and race/ethnicity: impact on breastfeeding intentions. J. Hum. Lact. 21:320-326.

60. Bonuck K., Trombley M., Freeman K., & McKee D. (2005) Randomized Controlled Trial Of A Pre- And Post-Natal Lactation Consultant Intervention Upon Duration And Intensity Of Breastfeeding Up To 12 Months. Pediatrics. 116:1413-26.

61. Vuguin P., Grinstein G., Freeman K., Saenger P., & DiMartino Nardi J. (2006) Prediction Models for Insulin Resistance in Girls with Premature Adrenarche. The Premature Adrenarche Insulin Resistance Score: PAIR Score. Horm. Res. 65:185-191.

62. Bonuck KA, Freeman K, & Trombley M. (2006) Randomized controlled trial of a prenatal and postnatal lactation consultant intervention on infant health care use. Arch Pediatr Adolesc Med. 160(9):953-960.

63. Stein M.W., Grishina A., Shaw R.J., Roberts J.H., Ricci Z.J., Adachi A., Freeman K., & Koenigsberg M. (2006) Gray Scale and Color Doppler Sonographic Features of the Vaginal cuff and Cervical Remnant After Hysterectomy. AJR. 2206:187: 1372-1376.

64. Freeman K. and Buchanan A. Statistical Analysis of Differences Among Laws Affecting Trade Secret Enforcement. Presented at the Hawaii International Conference on Statistics, Mathematics, & Related Fields and published in 2007 Conference Proceedings, Honolulu, Hawaii January 16-19, 2007.

65. Puri M., Freeman K., Garcia M., Nussbaum H., & Dimartino-Nardi J.R. (2007) Criteria for oral glucose tolerance testing of obese minority youth. J Pediatr Endocrinol Metab 20(6):703-709.

66. Kuncio D., Maganzini A., Shelton C., & Freeman K. (2007) Invisalign and Traditional Orthodontic Treatment Postretention Outcomes Compared Using the American Board of Orthodontics Objective Grading System. Angle Orthod. 77(5):864-869.

67. Stevanovic R.D., Fisher N.D., Lansang C., Freeman K., & Hollenberg N.K. (2007) Short and long term glycemic control and the state of the renin system in type 1 diabetes mellitus. J.Renin Angio.Aldo. Sys. 8(2):85-92.

68. Rosen D.J., Patel M.K., Freeman K., & Weiss P.R. (2007) A primary protocol for the management of ear keloids: results of excision combined with intraoperative and postoperative steroid injections. Plast Reconstr Surg. 120(5):1395-1400.

69. Freeman K., Bonuck K., & Trombley M. (2008) Breastfeeding and Infant Illness in Low-Income Minority Women: Prospective Cohort Study of Dose-Response Relationship. J Hum Lact. 24(1): 14-22.

70. Puri M., Flynn J.T., Garcia M., Nussbaum H., Freeman K., & Dimartino-Nardi J.R. (2008) The Frequency of Elevated Blood Pressure in Obese Minority Youth. J Clin Hypertens (Greenwich). 10(2):119-124.

71. Grant B.T., Amendo C., Freeman K., & Kraut R.A. (2008) Outcomes of placing dental implants in patients taking oral bisphosphonates: a review of 115 cases. J Oral Maxillofac Surg. 66(2):223-230.

72. Burge A.J., Freeman K.D., Klapper P.J., & Haramati L.B. (2008) Increased diagnosis of pulmonary embolism without a corresponding decline in mortality during the CT era. Clin Radiol. 63(4):381-386.

73. Freeman K., Tan H.K., Prusa A., Petersen E., Buffulano W., Malm G., Cortina-Borja M., & Gilbert R. for the European Multicenre Study on Congenital Toxoplasmosis. (2008) Predictors of retinochoroiditis in children with congenital toxoplasmosis:European, prospective cohort study. Pediatrics. 121(5):e1215-22.

74. Gilbert R.E., Freeman K., Lago E.G., Bahia-Oliveira L.M.G,. Tan H.K., Wallon M., Buffolano W., Stanford M.R, & Petersen E. for The European Multicentre Study on Congenital Toxoplasmosis (EMSCOT). (2008) Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe. PLoS Negl Trop Dis. 2(8):e277.

75. Grossman J., Ricci Z.J., Rozenblit A., Freeman K., Mazzariol F., & Stein MW. (2008) Efficacy of contrast-enhanced CT in assessing the endometrium. AJR. 191(3):664-669.

76. Segal M., Pedersen A.L., Freeman K., & Fast A. (2008) Medicare's New Restrictions on Rehabilitation Admissions: Impact on the Elderly. Am J Phys Med Rehabil. 87(11):872-82.

77. Bonuck K., Freeman K., & Henderson J. (2009) Growth and Growth Biomarker Changes After Adenotonsillectomy: Systematic Review and Meta-Analysis. Arch Dis Child. 94(2):83-91.

78. Shatat I.F., Freeman K.D., Vuguin P.M., Dimarino-Nardi J.R., & Flynn J.T. (2009) Relationship between adiponectin and ambulatory blood pressure in obese adolescents. Pediatr Res. 65(6):691-5.

79. Barnhart J.M., Wright N.D., Freeman K., Silagy F., Correa N., & Walker E.A. (2009) Risk perception and its association with cardiac risk and health behaviors among urban minority adults: the Bronx Coronary Risk Perception study. Am J Health Promot. 23(5):339-42.

80. Levsky J.M., Travin J.M., Spevack D.M., Menegus M.A., Huang P.W., Goldberg Y., Clark E.T., Banoth P., Freeman K.D., Tobin J.N., & Haramati L.B. (2009) Rationale and design of a randomized controlled trial comparing stress myocardial perfusion imaging with coronary CT angiography as the initial imaging study for intermediate-risk patients admitted with chest pain. J Cardiovasc Comput Tomogr. 3(4):264-71.

81. Jacobs L.G., Billett H.H., Freeman K., Dinglas C., & Jumaquio L. (2009) Anticoagulation for stroke prevention in elderly patients with atrial fibrillation, including those with falls and/or early-stage dementia: a single-center, retrospective, observational study. Am J Geriatr Pharmacother. Jun

7(3):159-66.

82. Hoffman N.D., Freeman K., & Swann S. (2009) Healthcare preferences of lesbian, gay, bisexual, transgender and questioning youth. J Adolesc Health. 45(3):222-9.

83. Scheinfeld M.H., Mahadevia S., Stein E.G., Freeman K., & Rozenblit A.M. (2010) Can lab data be used to reduce abdominal computed tomography (CT) usage in young adults presenting to the emergency department with nontraumatic abdominal pain? Emerg Radiol. 17(5):353-60.

84. Batta P., Shrivastava A., Engel H.M., Freeman K., & Mian U. (2010) The Effect of Partial Posterior Vitreous Detachment on Retinal Nerve Fiber Layer Thickness as Measured by Optical Coherence Tomography. Arch Ophthalmol. 128(6):692-7.

85. Arens R., Sin S., Willen S., Bent J., Parikh S.R., Freeman K., Wootton D.M., McDonough J.M., & Shifteh K. (2010) Rhino-sinus involvement in children with obstructive sleep apnea syndrome. Pediatr Pulmonol. 45(10):993-8.

86. Wright N.D., Barnhart J., Freeman K., & Walker E.A.. (2010) Coronary heart disease risk underestimation in a minority population: The Bronx Coronary Risk Perception Study. Prev Med. 51(5):434-5.

87. Kirsner R.S., Warriner R., Michela M., Stasik L., & Freeman K. (2010) Advanced Biological Therapies for Diabetic Foot Ulcers. Arch Dermat. 146(8):857-862.

88. Isasi C.R., Whiffen A., Campbell E., Florez Y., Freeman K., & Wylie-Rosett J. (2011) Forgetting our boys: High prevalence of obesity among inner city adolescent males. Prev Chronic Dis. 8(1):A23.

89. Cortina-Borja M.,Tan H.K., Thulliez P., Paul M., Pollak A., Buffolano W., Malm G., Salt A., Freeman K., Petersen E., & Gilbert R.E. (2010) Prenatal treatment for serious neurological sequelae of congenital toxoplasmosis. PLoS Med. 7(10).

90. Freeman K., Zonszein J., Islam N., Blank A., & Strelnick A. (2011) Mortality Trends and Disparities Among Racial/Ethnic and Gender Groups in New York City, 1990 to 2000. J Immigr Minor Health. 13(3):546-54.

91. Arens R., Sin S., Nandalike K., Rieder J., Khan U.I., Freeman K., Wylie-Rosett J., Lipton M.L., Wootton D.M., McDonough J.M., & Shifteh K. (2011) Upper Airway Structure and Body Fat Composition in Obese Children With Obstructive Sleep Apnea Syndrome. Am J Respir Crit Care Med. 183(6):782-7

92. Lui Y.W., Malhotra A., Farinhas J.M., Dasari S.B., Weidenheim K., Freeman K., & Lasala P.A. (2011) Dynamic perfusion MRI characteristics of dural metastases and meningiomas: a pilot study characterizing the first-pass wash-in phase beyond relative cerebral blood volume. Am J Roentgenol. 196(4):886-90.

93. Schachar J.L., Zampolin R.L., Miller T.S., Farinhas J.M., Freeman K., & Taragin B.H. (2011) External validation of the New Orleans Criteria (NOC), the Canadian CT Head Rule (CCTHR) and the National Emergency X-Radiography Utilization Study II (NEXUS II) for CT scanning in pediatric patients with minor head injury in a non-trauma center. Pediatr Radiol. 41(8):971-79.

94. Maloney K., Bastidas J., Freeman K., Olson T.R., & Kraut R.A. (2011) Cone Beam Computed Tomography and SimPlant Materialize Dental Software versus Direct Measurement of the Width and Height of the Posterior Mandible: An Anatomic Study. J Oral Maxillofac Surg. 69(7):1923-29.

95. Kim D.H., Rosenblum J.K., Panghaal V.S., Freeman K.D., & Lui Y.W. (2011) Differentiating Neoplastic from Nonneoplastic Processes in the Anterior Extradural Space. Radiology. 260(3):825-30.

96. Gartner R.D., Levin T.L., Borenstein S.H., Kim Han B., Blumfield E., Murphy R., & Freeman K. (2011) Interloop fluid in intussusception: what is its significance? Pediatr Radiol. 41(6): 727-31.

97. Bonuck K.A., Chervin R.D., Cole T.J., Emond A., Henderson J., Xu L., & Freeman K. (2011) Prevalence and persistence of sleep disordered breathing symptoms in young children: a 6-year population-based cohort study. Sleep. 34(7):875-84.

98. Blitman N.M., Baron L.S., Berkenblit R.G., Schoenfeld A.H., Markowitz M., & Freeman K. (2011) Feasibility of Using Single-Slice MDCT to Evaluate Visceral Abdominal Fat in an Urban Pediatric Population. AJR 197(2):482-87.

99. Dym R.J., Burns J., Freeman K., & Lipton M.L. (2011) Is Functional MR Imaging Assessment of Hemispheric Language Dominance as Good as the Wada Test?: A Meta-Analysis. Radiology. 261(2):446-55.

100. Farooqi K.M., Ceresnak S.R., Freeman K., & Pass R.H. (2011) Electrocardiograms Transmitted via Facsimile May Not Allow Accurate Interval Interpretation. Pacing Clin. Electrophys. 34(10):1283-7.

101. Zervos M.J., Freeman K., Vo L., Haque N., Pokharna H., Raut M., & Kim M. (2011) Complicated Skin and Soft Tissue Infections in Hospitalized Patients: Epidemiology and Outcomes. J Clin Microbiol. 50(2):238-45.

102. Freeman K. and Bonuck K. Snoring, Mouth-breathing, & Apnea Trajectories in a Population-Based Cohort Followed from Infancy to 81 Months: A Cluster Analysis. (2012) Int J Pediatr Otorhinolaryngol. 76(1):122-30.

103. Strauchler D., Freeman K., & Miller T. (2012) The impact of socioeconomic status and comorbid medical conditions on ionizing radiation exposure from diagnostic medical imaging in adults. J Am Coll Radiol. 9(1):58-63.

104. Lui Y.W., Farinhas J.M., Basalely A.M., Hsu K.A., Freeman K., & Bellow J.A. (2012) Assessment of an Introductory Cervicocerebral Catheter Angiography Learning Program: A Pilot Study. Am J Neuroradiol. 33(6):1041-5.

105. Bonuck K., Freeman K., Chervin R.D., & Xu L. (2012) Sleep-Disordered Breathing in a Population-Based Cohort: Behavioral Outcomes at 4 and 7 Years. Pediatrics. 129(4):e857-65.

106. Schmidt M.G., Attaway H.H., Sharpe P.A., John J. Jr., Sepkowitz K.A., Morgan A., Fairey S.E., Singh S., Steed L.L., Cantey J.R., Freeman K.D., Michels H.T., & Salgado C.D. (2012) Sustained Reduction of Microbial Burden on Common Hospital Surfaces Through The Introduction of Copper. J Clin Microbiol. 50(7):2217-23.

107. Sheh S.H., Bellin E., & Freeman K.D., Haramati L.B. (2012) Pulmonary embolism diagnosis and mortality with putmonary CT angiography versus ventilation-perfusion scintigraphy: evidence of overdiagnoisis with CT? Am J Roentgenol. 198(6):1340-5.

108. Freeman K., Strauchler D., & Miller T. (2012) The impact of socioeconomic status and comorbid medical conditions on ionizing radiation exposure from diagnostic medical imaging in children. J Am Coll Radio. 9(11):799-807.

109. Schnebel B, Mateer S, Maganzini AL, Freeman K. (2012) Clinical acceptability of two self-etch adhesive resins for the bonding of orthodontic brackets to enamel. J Orthod 39(4):256-61.

110. Salgado C.D., Sepkowitz K.A., John J.F., Cantey J.R., Attaway H.H., Freeman K.D., Sharpe P.A., Michels H.T., & Schmidt M.G. (2013) Copper surfaces reduce the rate of healthcare-acquired infections in the intensive care unit. Infect Control Hosp Epidemiol 34(5):479-86.

111. Salgado C.D., Sepkowitz K.A., John J.F., Cantey J.R., Attaway H.H., Freeman K.D., Sharpe P.A., Michels H.T., & Schmidt M.G. Reply to Harbarth et al.(2013) Infect Control Hosp Epidemiol. 34(9):997-9.

112. Nolan P.J., Freeman K., & Kraut R.A. (2013) Correlation Between Schneiderian Membrane Perforation and Sinus Lift Graft Outcome: A Retrospective Evaluation of 359 Augmented Sinus. J Oral Maxillofac Surg. Sep 23. [Epub ahead of print]

113. Maganzini A.L., Schroetter S.B., & Freeman K.( 2013) Improvement in smile esthetics following orthodontic treatment: A retrospective study utilizing standardized smile analysis. Angle Orthod. Nov 12. [Epub ahead of print]

114. Walder J.F., Freeman K., Lipp M.J., Nicolay O.F., & Cisneros G.J. (2013) Photographic and videographic assessment of the smile: Objective and subjective evaluations of posed and spontaneous smiles. Am J Orthod Dentofacial Orthop. 144(6):793-801.

115. Pickett Y.R., Kennedy G.J., Freeman K., Cummings J., & Woolis W. (2014) The Effect of Telephone-Facilitated Depression Care on Older, Medically Ill Patients. J Behav Health Serv Res Apr 10. [Epub ahead of print]

116a,b. Shapiro LF, Freeman K. (2014) The relationship between estrogen, estrogen receptors and periodontal disease in adult women: a review of the literature. NY State Dent J. 80(3):30-4, and JMichDentAssoc 11/2014.

117. Blitman NM, Anwar M, Brady KB, Taragin BH, Freeman K. (2015) Value of Focused Appendicitis Ultrasound and Alvarado Score in Predicting Appendicitis in Children: Can We Reduce the Use of CT Scans? Am J Roentgenol. 204(6):W707-12.

118. Kazimiroff J, Gotlibovky B, Bulger S, Dhar R, Rodriguez-Aguiar G, Umanski G, Kurtz K, Meissner P, Freeman K. The Association Between Oral Health, Overall Systemic Health and Age Using DMFT Scores. J Oral Sci Health. 2015;2(1):1-16.

119. Pulido M, Dauber S, Tully B, Hamilton P, Smith MJ, Freeman K. (2015) Measuring Knowledge Gains Following a Child Sexual Abuse Prevention Program among Urban Students in a Cluster Randomized Evaluation. Am J Public Health. May 14:e1-e7.

120. Levsky JM, Spevack DM, Travin MI, Menegus MA, Huang PW, Clark ET, Kim C, Hirschhorn E, Freeman KD, Tobin JN, Haramati LB. Coronary Computed Tomography Versus Radionuclide Myocardial Perfusion Imaging in Chest Pain Patients Admitted to Telemetry: A Randomized Clinical Trial. Accepted 03/31/15 by Annals of Internal Medicine.

TEACHING

ALBERT EINSTEIN COLLEGE OF MEDICINE

Masters Program in Clinical Research (CRTP)

• Short course: clinical trials and meta-analysis 2004-present.

• Multiple Regression and Multiple Logistic Regression 1998, 1999, 2000.

• Statistical Mentor of all students, 1998-2005.

• Epidemiology I, II: Introduction and advanced topics in clinical trials 2004-06.

• Epidemiology II: Meta-Analysis 2006

Short Courses

• Basic Concepts of Statistical Inference (hypothesis testing, estimation, statistical significance, Type I, II errors, power) 1987, 1990, 1991.

• Review of Bias in the Medical Literature.” 1987, 1988, 1989.

• Evaluation of Medical Research Reports in the Medical Literature (common deficiencies in reporting research results, common deficiencies in statistical analysis) 1990, 1991.

• Principles of Study Design in Clinical Trials (endpoint variables, sample size, randomization and stratification, elements of protocol writing, ethical considerations) 1990, 1991, 1995.

• Multiple Regression and Multiple Logistic Regression. 1993, 1995.

Medical Student Instruction and Clinical Departments

• Epidemiological Topics and Bioethics. First Year Medical Students, 1993, 1994, 1995.

• Clinical Trial Design and Analysis, 1995.

• Introduction to Biostatistical Methods and Critical Review of the Medical Literature, 1989 - 2011

Departments/Divisions: Neurology, Dentistry, Radiation Oncology, Family Medicine, Ophthalmology, Radiology, Geriatrics, Pacemaker Unit, Cardiology, Critical Care Medicine.

INSTITUTE OF CHILD HEALTH, UNIVERSITY COLLEGE LONDON

• Tutor (instructor) for course in Evidence-Based Child Health sponsored by the Centre for Evidence-Based Child Health 2002.

COLUMBIA UNIVERSITY

• School of Public Health: Introduction to Biostatistics. 1991.

• Graduate School of Nursing: Research Methods 1991, 1992.

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