Pharmawiki - Resources for B Pharm, M Pharm, GPAT, NIPER



?Pharmacology MCQ for Anti Cancer Chemotherapy DrugsANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCERAll of the following antiviral drugs are the analogs of nucleosides, EXCEPT:a) Acyclovirb) Zidovudinec) Saquinavird) DidanozineTick the drug, a derivative of adamantane:a) Didanozineb) Rimantadinec) Gancyclovird) FoscarnetTick the drug, a derivative of pyrophosphate:a) Foscarnetb) Zidovudinec) Vidarabined) AcyclovirTick the drug, inhibiting viral DNA synthesis:a) Interferonb) Saquinavirc) Amantadined) AcyclovirTick the drug, inhibiting uncoating of the viral RNA:a) Vidarabineb) Rimantadinec) Acyclovird) DidanozineTick the drug, inhibiting viral reverse transcriptase:a) Zidovudineb) Vidarabinec) Rimantadined) GancyclovirTick the drug, inhibiting viral proteases:a) Rimantadineb) Acyclovirc) Saquinavird) ZalcitabineTick the drug of choice for herpes and cytomegalovirus infection treatment:a) Saquinavirb) Interferon alfac) Didanozined) Acyclovir136Tick the drug which belongs to nonnucleoside reverse transcriptase inhibitors:a) Zidovudineb) Vidarabinec) Nevirapined) GancyclovirAll of the following antiviral drugs are antiretroviral agents, EXCEPT:a) Acyclovirb) Zidovudinec) Zalcitabined) DidanozineTick the drug used for influenza A prevention:a) Acyclovirb) Rimantadinec) Saquinavird) FoscarnetTick the drug used for HIV infection treatment, a derivative of nucleosides:a) Acyclovirb) Zidovudinec) Gancyclovird) TrifluridineTick the antiviral drug which belongs to endogenous proteins:a) Amantadineb) Saquinavirc) Interferon alfad) PencyclovirTick the drug which belongs to nucleoside reverse transcriptase inhibitors:a) Didanosineb) Gancyclovirc) Nevirapined) VidarabineAll of the following antiviral drugs are anti-influenza agents, EXCEPT:a) Acyclovirb) Amantadinec) Interferonsd) RimantadineTick the unwanted effects of zidovudine:a) Hallucinations, dizzinessb) Anemia, neutropenia, nausea, insomniac) Hypertension, vomitingd) Peripheral neuropathyTick the unwanted effects of intravenous acyclovir infusion:a) Renal insufficiency, tremors, deleriumb) Rash, diarrhea, nauseac) Neuropathy, abdominal paind) Anemia, neutropenia, nausea, insomniaTick the drug that can induce peripheral neuropathy and oral ulceration:a) Acyclovireb) Zalcitabinec) Zidovudined) SaquinavirTick the unwanted effects of didanozine:a) Hallucinations, dizziness, insomniab) Anemia, neutropenia, nauseac) Hypertension, vomiting, diarrhead) Peripheral neuropathy, pancreatitis, diarrhea, hyperuricemiaTick the unwanted effects of indinavir:a) Hypotension, vomiting, dizzinessb) Nephrolithiasis, nausea, hepatotoxicityc) Peripheral neuropathy, pancreatitis, hyperuricemiad) Anemia, neutropenia, nauseaTick the drug that can induce nausea, diarrhea, abdominal pain and rhinitis:137a) Acyclovireb) Zalcitabinec) Zidovudined) SaquinavirAll of the following effects are disadvantages of anticancer drugs, EXCEPT:a) Low selectivity to cancer cellsb) Depression of bone marrowc) Depression of angiogenesisd) Depression of immune systemRational combination of anticancer drugs is used to:a) Provide synergism resulting from the use of anticancer drugs with different mechanisms combinationb) Provide synergism resulting from the use of anticancer drugs with the same mechanisms combinationc) Provide stimulation of immune systemd) Provide stimulation of cell proliferationTick the anticancer alkylating drug, a derivative of chloroethylamine:a) Methotrexateb) Cisplatinc) Cyclophosphamided) CarmustineTick the anticancer alkylating drug, a derivative of ethylenimine:a) Mercaptopurineb) Thiotepac) Chlorambucild) ProcarbazineTick the group of hormonal drugs used for cancer treatment:a) Mineralocorticoids and glucocorticoidsb) Glucocorticoids and gonadal hormonesc) Gonadal hormones and somatotropind) InsulinTick the anticancer alkylating drug, a derivative of alkylsulfonate:a) Fluorouracilb) Carboplatinc) Vinblastined) BusulfanTick the anticancer drug of plant origin:a) Dactinomycinb) Vincristinec) Methotrexated) ProcarbazineAction mechanism of alkylating agents is:a) Producing carbonium ions altering protein structureb) Producing carbonium ions altering DNA structurec) Structural antagonism against purine and pyrimidined) Inhibition of DNA-dependent RNA synthesisTick the anticancer drug, a pyrimidine antagonist:a) Fluorouracilb) Mercaptopurinec) Thioguanined) MethotrexateMethotrexate is:a) A purine antagonistb) A folic acid antagonistc) An antibioticd) An alkylating agentTick the antibiotic for cancer chemotherapy:a) Cytarabineb) Doxorubicinc) Gentamycind) EtoposideFluorouracil belongs to:a) Antibioticsb) Antimetabolitesc) Plant alkaloidsd) Bone marrow growth factorTick the action mechanism of anticancer drugs belonging to plant alkaloids:a) Inhibition of DNA-dependent RNA synthesisb) Cross-linking of DNAc) Mitotic arrest at a metaphased) Nonselective inhibition of aromatasesANTIVIRAL AGENTS. AGENTS FOR CHEMOTHERAPY OF CANCERGeneral contraindications for anticancer drugs are:a) Depression of bone marrowb) Acute infectionsc) Severe hepatic and/or renal insufficiencyd) All of the aboveAction mechanism of methotrexate is:a) Inhibition of dihydrofolate reductaseb) Activation of cell differentiationc) Catabolic depletion of serum asparagined) All of the aboveTick the anticancer drug belonging to inorganic metal complexes:a) Dacarbazineb) Cisplatinc) Methotrexated) VincristineTick the indication for estrogens in oncological practice:a) Leukemiab) Cancer of prostatec) Endometrial cancerd) Brain tumorsEnzyme drug used for acute leukemia treatment:a) Dihydrofolate reductaseb) Asparaginasec) Aromatased) DNA gyraseAll of the following drugs are derivatives of nitrosoureas, EXCEPT:a) Carmustineb) Vincristinec) Lomustined) SemustineTick the group of drugs used as subsidiary medicines in cancer treatment:a) Cytoprotectorsb) Bone marrow growth factorsc) Antimetastatic agentsd) All of the aboveTick the estrogen inhibitor:a) Leuprolideb) Tamoxifenc) Flutamided) AnastrozoleTick the antiandrogen drug:a) Flutamideb) Aminoglutethimidec) Tamoxifend) TestosteroneTick the drug belonging to aromatase inhibitors:a) Octreotideb) Anastrozolec) Flutamided) TamoxifenTick the drug belonging to gonadotropin-releasing hormone agonists:a) Leuprolideb) Tamoxifenc) Flutamided) Anastrozole? ................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download