Breast Cancer - NHS Wales

Carboplatin: Adjust dose using Calvert formula. Contraindicated if Cr Cl < 20ml/min. Neutrophils < 1.0 x 109/L defer dose. Platelets < 100 x 109/L defer dose. AST or ALT > 1.5 x upper limit normal reduce dose by 25% > 3.5 x upper limit normal discontinue ................
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