Australian public assessment report for Aflibercept rch

Aflibercept was considered inactive if the log cell kill is 2.8. Administration of aflibercept SC on days 13, 16 and 19 post-implantation at doses of 1040 mg/kg (but not ≤2.5 mg/kg) decreased tumour volume and ascites produced by the growth of implanted murine renal cell carcinoma (RENCA) cells ... ................
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