AMBER E - University of Pittsburgh



July 2015

CURRICULUM VITAE

Janel Hanmer, MD, PhD

Assistant Professor of Medicine and Clinical and Translational Science

University of Pittsburgh

BIOGRAPHICAL INFORMATION

Name: Janel Hanmer, MD, PhD Birth Year: 1979

Home Address: available on request Birth Place: North Carolina

Home Phone: available on request Citizenship: U.S.

Business Address: Center for Research on Health Care E-Mail: hanmerjz@upmc.edu

Division of General Internal Medicine

University of Pittsburgh

230 McKee Place, Suite 600

Pittsburgh, PA 15213

Business Phone: (412) 586-9847 Business Fax: (412) 692-4838

EDUCATION AND TRAINING

Undergraduate

1994-1999 Carnegie Mellon University BS (1999), Double Major in Technical

Pittsburgh, PA Writing and Chemistry

Graduate

2001–2003 University of Wisconsin Medical School

Madison, WI

2003–2007 University of Wisconsin Medical School PHD (2007)

Department of Population Health Sciences

Madison, WI

2008 –2010 University of Wisconsin Medical School MD (2010)

Madison, WI

Postgraduate

2007–2008 University of Wisconsin Medical School Postdoctoral Scholar

Department of Population Health Sciences

Madison, WI

2010-2013 University of Iowa Resident

Department of Internal Medicine

APPOINTMENTS AND POSITIONS

Academic Appointments

2014–present Assistant Professor of Clinical and Translational Science (secondary appointment), Institute for Clinical Research Education (ICRE) and Clinical and Translational Science Institute (CTSI), University of Pittsburgh.

2013–present Assistant Professor Member, Section of Decision Making, Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh.

CERTIFICATION AND LICENSURE

Specialty and Other Certification

2014 Certification Advanced Cardiac Life Support.

2013 Certification, American Board of Internal Medicine.

Medical and Other Professional Licensure

2013 Medical License and Surgeon, Commonwealth of Pennsylvania.

2014 Medical License, North Carolina

MEMBERSHIPS IN PROFESSIONAL AND SCIENTIFIC SOCIETIES

2003 Society for Medical Decision Making

2010 Society of General Internal Medicine

2013 International Society for Quality of Life Research

HONORS AND AWARDS

2012 Johns Hopkins General Internal Medicine Housestaff Research Awards- David Levine

Research Award for “Is Insurance Status Associated with the Transfer of Hospitalized Patients?”

2012 Abboud Internal Medicine Resident Award for Research, University of Iowa

2006 Best Student Podium Presentation at the 11th Annual International Meeting of ISPOR for “A Bayesian Estimation of an Average SF-6D Score from Commonly Reported SF-12 Statistics

2003- 2006 AHRQ T-32 Pre-doctoral NRSA Trainee

2001-2003 NIH Integrated Training for Physician Scientists Trainee

2008-2010

1999 Phi Beta Kappa

PUBLICATIONS

Refereed Articles

1. Franks P, Hanmer J, Fryback DG. Relative disutilities of 47 risk factors and conditions assessed with seven preference-based health status measures in a national U.S. sample: toward consistency in cost-effectiveness analyses. Med Care. 2006; 44:478-85. PMID: 15970790

2. Hanmer J, Lawrence W, Anderson J, Kaplan R, Fryback DG. Report of Population Norms for the Non-Institutionalized U.S. Adult Population for Seven Health Related Quality of Life Scores. Med Decis Making. 2006; 26:391-400. [Published with editorial comment and online supplement.] PMID: 16641667

3. Fryback DG, Dunham N, Palta M, Hanmer J, Buechner J, Cherepanov D, Herrington S, Hays RD, Kaplan RM, Ganiats T, Feeny D, Kind P. The National Health Measurement Study: Simultaneous U.S. Norms for Six Generic Health-Related Quality-of-Life Instruments. Med Care. 2007; 45:1162-1170. PMID: 18007166

4. Hanmer J, Hays RD, Fryback DG. Mode of Administration is Important in U.S. National Estimates of Health-Related Quality of Life. Med Care. 2007; 45:1171-1179. PMID 18007167

5. Hanmer J. Predicting an SF-6D Preference-Based Score using MCS and PCS Scores from the SF-36 or SF-12. Value in Health. 2009;12:958-66.PMID:19490549

6. Hanmer J, Vanness D, Gangnon R, Palta M, Fryback DG. Three methods tested to model SF-6D health utilities for health states involving comorbidity/co-occurring conditions. Journal of Clinical Epidemiology. 2009;63:331-341 .

7. Sellers S, Cherepanov D, Hanmer J, Fryback DG, Palta M. Interpersonal discrimination and health related quality of life among black and white men and women in the United States. Quality of Life Research. 2013;22:1307-1312

8. Makki N, Swaminathan PD, Hanmer J, Olshansky B. Do implantable cardioverter defibrillators improve survival in patients with chronic kidney disease at high risk of sudden cardiac death? A meta-analysis of observational studies. Europace, 2014;16(1), 55-62.

9. Hanmer J, Lu X, Rosenthal GE, Cram P. Insurance Status and the Transfer of Hospitalized Patients: An Observational Study. Ann Intern Med. 2014;160(2):81-90.

10. Ashrith G, Gupta D, Hanmer J, Weiss RM. Cardiac Magnetic Resonance Characterization of Left Ventricular Noncompaction Provides Independent Prognostic Information in Patients with Incident Heart Failure or Suspected Cardiomyopathy: A Retrospective Analysis. J Cardiovasc Magn Reson 2014;16, 64.

11. Hanmer J, Cherepanov D, Palta M, Kaplan RM, Feeny D, Fryback DG. Health Condition Impacts in a National Representative Cross-Sectional Survey Vary Substantially by Preference-Based Health Index. In press at Medical Decision Making.

12. Hanmer J, Feeny D, Fischhoff B, Hays R, Hess R, Pilkonis P, Revicki D, Roberts M, Tsevat J, Yu L. The PROMIS of QALYs. Health and Quality of Life Outcomes. 2015; 13(1):122

Published Abstracts

1. Fryback DG, Hanmer J, Cruickshanks K, Klein R, Klein B. “Bayesian Analysis of Health Status and Quality of Life Data: (Preliminary) Example from the Beaver Dam Studies.” ISOQOL Symposium “Stating the Art: Advancing Outcomes Research Methodology and Clinical Applications,” June 2004, Boston, MA.

2. Fryback DG, Hanmer J, Rosenberg M, Cruickshanks K. “Bayesian estimation of Dam studies.” IHEA 5th World Congress “Investing in Health,” July 2005. Barcelona, Spain.

3. Hanmer J, Fryback DG. “Do Large National Surveys Yield Equivalent Population Norms for Health Related Quality of Life Measures?” 27th Annual Meeting of the Society for Medical Decision Making, joint poster session with the International Society for Quality of Life Research “Translating Medical Decision Making Research into Practice,” October 2005. San Francisco, CA.

4. Hanmer J, Fryback DG. “A Bayesian Estimation of an Average SF-6D Preference Based Score from Commonly Reported SF-12 Statistics.” ISPOR 11th Annual International Meeting. May 2006. Philadelphia, PA.

5. Fryback DG, Palta M, Dunham N, Hanmer J, Herrington S, Cherepanov D, Buechner J, Hays RD, Kaplan RM, Ganiats T, Feeny D, Kind P. “The National Health Measurement Study: US Data for Six Generic HRQOL Indices.” ISOQOL 13th Annual International Meeting. October 2006. Lisbon, Portugal.

6. Dunham N, Fryback DG, Palta M, Hanmer J, Herrington S, Cherepanov D, Beuchner J. “The National Health Measurement Study: Do Different Generic Indices of Health-Related Quality of Life Yield Similar Population Norms?” 28th Annual Meeting of the Society for Medical Decision Making. October 2006. Boston, MA.

7. Hanmer J, Fryback DG, Palta M, Dunham N, Herrington S, Cherepanov D, Beuchner J. “National Values for Health Related Quality of Life Measures in the United States: Mode of Administration May Matter.” 28th Annual Meeting of the Society for Medical Decision Making. October 2006. Boston, MA.

8. Hanmer J, Fryback DG, Palta M, Dunham N, Herrington S, Cherepanov D, Beuchner J. “Responsiveness in 7 Co-Administered Generic Health Related Quality of Life Measures in the National Health Measurement Study.” 28th Annual Meeting of the Society for Medical Decision Making. October 2006. Boston, MA.

9. Hanmer J, Franks P, Fryback DG. “Predicting Disease-Burden in EQ-5D US Units from Seven Other Measurement Systems (EQ-5D UK, HALEX, HUI MARK 2, HUI MARK 3, QWB-SA, SF-6D(12), SF-6D(36)).” ISPOR 12th Annual International Meeting. May 2007. Arlington, VA.

10. Hanmer J, Gangnon R, Vanness D, Fryback DG. “Does Domain-Based Modeling of Multiple Health Conditions Improve Health-Related Quality of Life Estimates Compared to Summary-Score-Based Modeling for the SF-6D?” 29th Annual Meeting of the Society for Medical Decision Making. October 2007. Pittsburgh, PA.

11. Hanmer J, Vanness D, Gangnon R, Fryback DG. “Modeling Co-occurring Health Conditions to Predict Health Utility from Generic Health-Related Quality of Life Indexes” 29th Annual Meeting of the Society for Medical Decision Making. October 2007. Pittsburgh, PA.

12. Cherepanov D, Palta M, Hanmer J, Fryback DG. “Do Differences in Preference-based HRQoL Scores for Common Chronic Conditions in the U.S. Differ by Gender or Race?” 30th Annual Meeting of the Society for Medical Decision Making. October 2008. Philadelphia, PA.

13. Fryback DG, Dunham NC, Palta M, Hanmer J, Cherepanov D, Hays RD, Kaplan RM, Ganiats TG, Feeny D, Kind P. “The National Health Measurement Study – A Public Data Set for Health-Related Quality-of-Life Research” 30th Annual Meeting of the Society for Medical Decision Making. October 2008. Philadelphia, PA.

14. Hanmer J, Paulsen A, Cherepanov D, Palta M, Kaplan R, Feeny D, Fryback DG. “Health Condition Impacts as Measured by Common Health Utility Indexes in a Cross-Sectional Survey: Disappointing News for Cost-Effectiveness Analyses” 31th Annual Meeting of the Society for Medical Decision Making. October 2009. LA, CA.

15. Vanness D, Hanmer J. Modeling Crosswalk Functions: A Bayesian Beta Regression Approach.” 32nd Annual Meeting of the Society for Medical Decision Making. October 2010. Toronto, Canada.

16. Hanmer J, Sellers S, Cherepanov D, Fryback DG. “Interpersonal Discrimination and Health Utility Scores Among Black and White Men and Women in the United States.” 34th Annual Meeting of the Society for General Internal Medicine. May 2011. Phoenix, AZ.

17. Hanmer J, Cram P. “Is Insurance Status Associated with the Transfer of Hospitalized Patients?” 35th Annual Meeting of the Society for General Internal Medicine. May 2012. Orlando, FL.

18. Ashrith G, Hanmer J, Gupta D, Weiss R. “Paradoxical Inverse Relationship between Regional Contractile Function in Compacted vs. Trabeculated Segments in Patients with Left Ventricular Noncompaction.” 16th Annual Meeting of the Heart Failure Society of America. Sept 2012. Seattle, WA.

19. Hanmer J, Hess R, Sullivan SM, Teuteberg JJ, Kavalieratos D. Collection of health utility data in a clinical setting: comparison to a nationally-representative sample. 21st Annual Meeting of the International Society of Quality of Life Research, October 2014. Berlin, Germany.

20. Hanmer J, Feeny D, Fischhoff B, Hays R, Hess R, Pilkonis P, Revicki D, Roberts M, Tsevat J, Yu L. “A community sample’s perception of cause-and-effect directional among health domains.” 22st Annual Meeting of the International Society of Quality of Life Research, October 2015. Vancouver, Canada.

21. Hanmer J, Cherepanov D. “A single question about a respondent’s perceived financial ability to pay monthly bills explains more variance in health utility scores than absolute income and assets questions.” 22st Annual Meeting of the International Society of Quality of Life Research, October 2015. Vancouver, Canada.

22. Hanmer J, Feeny D, Fischhoff B, Hays R, Hess R, Pilkonis P, Revicki D, Roberts M, Tsevat J, Yu L. “Selection of key PROMIS domains for a preference-based scoring system.” 37th Annual Meeting of the Society for Medical Decision Making. October 2015. Saint Louis, MO.

23. Dewitt B, Hanmer J, Davis A. “Preference aggregation in the Health Utilities Index Mark 2 and 3.” 37th Annual Meeting of the Society for Medical Decision Making. October 2015. Saint Louis, MO.

24. Yeh J, Hanmer J, et al. “Health utility scores in childhood cancer survivors: insights from the childhood cancer survivor study.” 37th Annual Meeting of the Society for Medical Decision Making. October 2015. Saint Louis, MO.

PROFESSIONAL ACTIVITIES: TEACHING

2014-present Small Group Leader, “Methods and Logic in Medicine” University of Pittsburgh Medical School.

2013-present Attending Physician on Inpatient Wards. University of Pittsburgh Medical Center.

2011-2013 Senior Resident, University of Iowa Hospitals and Clinics, Supervising and teaching interns and medical students on clinical rotations 16 weeks a year. Lead several journal clubs a year. Teaching Resident for the medical student rotation February 2013.

2011 Short Course Lecturer, Society for Medical Decision Making , Health Status and Utilities

2008, 2010 Associate Lecturer, Department of Population Health Sciences, University of Madison, Instructor for courses entitled “Measuring Health Outcomes” and “Secondary Analysis of Large Datasets for Population Health Research”.

1999-2000 Kaitong Foreign Language School- Luoyang, Henan, China, Preschool and primary school English Teacher. Taught classes in spoken English while living independently in China.

PROFESSIONAL ACTIVITIES: MENTORING AND ADVISING

2011-2014 Justin Lo, PhD Candidate University of Wisconsin-Madison.

2015-present Jeremy Adams, PhD Candidate, University of Pittsburgh

PROFESSIONAL ACTIVITIES: RESEARCH

Previous Grant Support

|Years |Grant Title and Number |Role and % Effort |Source and Dollar Amount |

|2006-2007 |Estimating Health Utilities and Co-Occurring Conditions |PI with Dennis |AHRQ Dissertation Grant |

| |1 R36 HS016574 |Fryback as the | |

| | |Primary Advisor | |

| |This study is a randomized clinical trial of oral nicotine replacement therapy for people who do not smoke every day. So-called |

| |non-daily smokers are increasingly prevalent (up to 25-35% of adult smokers) yet medication therapy has not been studied in this |

| |population. This study will combine the RCT design with ecological momentary assessment to study the process of quitting (and, most |

| |likely, the process of relapse) among non-daily smokers. |

|2004 –2008 |Norms and Performance Comparisons for 5 Health Indexes |Fryback(PI) Research |NIH/NIA |

| |P01 AG20679 |Assistant as PhD | |

| | |Student and | |

| | |Postdoctoral Scholar | |

| |This project includes both a nationally representative random digit dial survey and a longitudinal patient study. Both samples include|

| |the 5 main generic health related quality of life measures allowing comparisons of normative values and responsiveness of these |

| |measures. |

Current Grant Support

|Years |Grant Number and Title |Role and % Effort |Source and Dollar Amount |

|2013-2015 |The University of Pittsburgh Clinical and Translational Science | |NIH/NCATS |

| |Institute –Clinical Research Scholars Program | |102,768 |

| |KL2 TR000146 (Reis) 10/1/13 – 9/30/15 | | |

| |The primary focus of the CTSI is to develop, nurture, and support a cadre of highly trained clinical and translational scientists. |

| |Through integration and innovation, the CTSI will excel in the development of new biomedical knowledge and the translation of that |

| |knowledge from the basic and preclinical research settings to individuals, communities, and health practice. The purpose of the KL2 is|

| |to support the early career development of clinical researchers from a variety of disciplines engaged in all types of clinical research|

|Years |Grant Number and Title |Role and % Effort |Source and Dollar Amount |

|2014-2016 |Quality Adjusted Life Expectancy Estimates for the US General |PI 10% |NIH/NIA |

| |Population | |288,898 |

| |1 R03 AG048855 10/1/13 – 9/30/15 | | |

| |Accurate measures of population health are necessary to inform policy, set research agendas, and allocate public resources. One |

| |commonly used measure of population health is Quality Adjusted Life Expectancy – a metric which combines mortality and morbidity into a|

| |single value. This project will improve current Quality Adjusted Life Expectancy estimates by using large nationally-representative |

| |datasets, modeling expected changes in morbidity, and allowing estimates for specific health conditions. |

PROFESSIONAL ACTIVITIES: CURRENT RESEARCH (AND CLINCAL) INTERESTS

• Clinically, I treat adult patients admitted to general medicine wards.

• My primary research interest is how we quantify health for analysis.  I am particularly interested in how we construct and use health utility measures.  I have experience comparing different health utility measures and exploring how we should apply these measures (mode of administration, combining multiple health conditions in a model, etc).  My current research focuses on constructing a health utility measure for an item-response theory based health measurement system (particularly PROMIS).

• My other area of research interest is in the transfer of hospitalized patients.  Who gets transferred?  Where are they transferred to?  When are interventions performed?

PROFESSIONAL ACTIVITIES: SERVICE

Consultancies

2004-2005 Consultant to Institute of Medicine Committee to Evaluate Measures of Health Benefits for Environmental, Health, and Safety Regulation

County, State, National, and International Service

2005- Present Peer Reviewer: Archives of Ophthalmology, Gender Medicine, Health and Quality of Life Outcomes, International Journal of Environmental Research and Public Health, Journal of Clinical Epidemiology Medical Care, Medical Decision Making, PLoS ONE, Quality of Life Research, Value in Health

2006- Present Referee for presentation abstracts: Society for Medical Decision Making’s annual meeting and Society for General Internal Medicine’s annual meeting

2007 Referee for funding applications: Netherlands Organization for Health Research and Development

2014-Present Sentinel Reader for Evidence-Based Medicine from Health Information Research Unit at McMaster University

2016-2018 Medical Decision Making Editorial Board

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