Motility Disorder Extremes Oropharyngeal, Colon and Anorectum
[Pages:57]Motility Disorder Extremes Oropharyngeal, Colon and Anorectum
Amy Foxx-Orenstein, DO, MACP, FACP Professor of Medicine Division of Gastroenterology and Hepatology Motility Section Mayo Clinic
?2018 MFMER | slide-1
Goal
Educate on clinically relevant oropharyngeal, colon and anorectal motility disorders encountered in practice
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Why Are Motility Disorders Important?
? Motility disorders are common ? You will see them! ? Affects 15-20% of the adult population
? $$ There can be considerable expense in the work-up/management. ? Cost effective evaluation is efficient
? Differential can be broad
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Oropharyngeal Dysphagia
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Define Dysphagia: sensation of difficulty or
abnormality of swallowing
? Transfer dysphagia:
? Difficulty initiating a swallow ? Symptoms: Nasopharyngeal regurgitation, aspiration, retention
? Esophageal dysphagia:
? Difficulty swallowing seconds after initiation ? Sensation of food getting stuck
Lembo A. Up to Date 2017
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NOT Oropharyngeal Dysphagia: Globus
Intermittent sensation of a lump in the throat Occurs between meals, independent of swallowing NO dysphagia, odynophagia, GERD, EoE or motility
disorder causing symptoms
Aziz Q. et al. Gastroenterology 2016
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Causes of Oropharyngeal Dysphagia
Structural Iatrogenic
Cricopharyngeal Medications bar
Zenker's
Postsurgical
Cervical web
Radiation
Oral tumors Cleft palate
Corrosive
Infectious Metabolic
Mucositis
Amyloidosis
Myopathic
Connective tissue disease
Neurological
Brainstem tumors
Botulism
Cushing's
Dermatomyositis Trauma
Lyme disease Thyrotoxicosis Myasthenia gravis
Stroke
Syphilis
Wilson disease Sarcoidosis
Celebral palsy
Paraneoplastic Multiple Sclerosis syndromes
Dystrophies
Post-polio
Tardive dyskinesia
Dementia Parkinson's
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Oropharynx anatomy
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