BREAST/ADJUVANT



A011202 Arsenault local IRB 50

(3) Randomized Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Pts Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemo

Clinical T1-3, N1, MO

Step 2 temporarily closed

BO41843 (D) Pruitt WIRB

Phase III Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Combined with Palbociclib Compared with Letrozole Combined with Palbociclib in Pts with ER+/HER2 Negative Locally Advanced or Metastatic Breast Cancer

S1706 (D) Pruitt CIRB

A Phase II Randomized Trial of Olaparib Administered Concurrently with Radiotherapy vs Radiotherapy Alone for Inflammatory Breast Cancer

S1418 D) Pruitt CIRB

(7) A Randomized Phase III Trial to Evaluate the Pruitt Efficacy and Safety of MK-3475 as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer with ≥1cm Residual Invasive Cancer or Positive Lymph Nodes after Neoadjuvant Chemotherapy

A021502 (D) Ravipati CIRB

Randomized Trial of Standard Chemotherapy Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair

NRG-GI004/1610 (D) Ravipati CIRB

Colorectal Cancer Metastatic dMMR

Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with or without Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients with Deficient DNA Mismatch Repair (dMMR) Metastatic Colorectal Cancer

SWOG LungMap Ravipati CIRB

(8) Targeted Treatment for Advanced NSCLC

S1900B sub-study: (D) Ravipati CIRB

A Phase II Study of LOXO-292 in Patients with RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)

APL-101-01 (SPARTA) (D) Ravipati Advarra

Apollomics Inc. / Phase 1 / 2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects with Non-Small Cell Lung Cancer with c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

S1801 (D) Ravipati CIRB

A Phase II Randomized Study of Adjuvant vs Neoadjuvant MK-3475 (Pembrolizumab) for Clinically Detectable Stage III-IV High Risk Melanoma

EA3161 (D) Ravipati CIRB

A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate Risk HPV Positive OPCA

NRG-HN005 (D) Ravipati CIRB

A Randomized Phase II/III Trial of De-intensified Radiation Therapy for Patients with Early-Stage, p16-Positive, Non-Smoking Associated Oropharyngeal Cancer

BlueStar Genomics Pruitt Advarra

iProcess Global Research Inc. / Collection & Distribution of Biofluids and Tumor Tissue Biospecimens for Research Purposes

CITY OF HOPE Ravipati local IRB 400

(11) Molecular Genetics Studies of Cancer Patients and Their Relatives

Revisions made

Closure: A011401

Temporary Closure:

New: BO41843, APL-101-01

Pending IRB:

Pending Activation:

-----------------------

Breast

TNBC

Colon

Lung-non small cell

Melanoma

Oropharyngeal

Tissue Banking

Genetics

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