Cholesterol and Cancer , in the Balance

Fig. 1. Regulation of lipid metabolism by oncogenic signalling pathways. Many cancer cells show high rates of de novo lipid synthesis. Fatty acids are required for the production of phosphoglycerides, which, together with cholesterol, can be used for building cell membranes. Tria-cylglycerides and cholesterylesters are stored in lipid droplets ... ................
................