Autoimuninės kilmės glomerulų pažeidimas

VILNIUS UNIVERSITY

Autoimunin?s kilm?s glomerul? pa?eidimas

Prof. Arvydas Laurinavi?ius

Vilnius 2018-04-13

Autoiminin?s kilm?s glomerul?

pa?eidimas

? ANTI-GBM GLOMERULONEFRITAS, GOODPASTURE SINDROMAS

? ANCA VASKULITAI

? VILKLIGINIS (LUPUS) NEFRITAS

? KITI IMUNOKOMPLEKSINIAI

? ?IDIOPATINIS¡° MEMBRANOPROLIFERACINIS GN

? MEMBRANIN? NEFROPATIJA (fosfolipaz?s A2 receptoriai)

? C3 GLOMERULOPATIJOS

? TROMBIN?S MIKROANGIOPATIJOS (AFAS IR KT.)

2

Minimal change NS

Idiopathic

FSGS

Drugs

primary

NSAID

secondary

Antibiotics

Nephrotic

Membranous nephropathy

other

Endocapillary GN

Malignancy

sudden onset

Crescentic GN

Carcinoma

insidious

anti-GBM

Lymphoproliferative

pauci-immune

other

Nephritic

immune-complex

Autoimmune

acute

Membranoproliferative

ANCA

immune-complex

Anti-GBM

subacute (RPGN)

cryoglobulin

SLE

chronic

DDD/C3 GN

Anti-phospholipid

biopsija

atsakymas

paraprotein

RA

Proteinuria subnephrotic

TMA

SS

Hematuria

Mesangioproliferative

other

IgA nephropathy

Bacterial infections

persistent micro

GBM abnormalities

Acute Streptococcal

recurrent macro

Alport

Persistent other

TBMD

Viral infections

Renal insufficiency

I?samiPathologic

diagnoz?

optimaliam gydymui

accumulations

HBV

acute

Amyloid

HCV

Diabetic glomerulosclerosis

HIV

chronic

Fabry

other

Arterial hypertension

Myeloma kidney

Hereditary

Oxalosis

Other kidney disease

Other systems involved

Tubular, Interstitial, Vascular injury

Other disease

Nephropathology map

Nephrotic

sudden onset

insidious

Nephritic

acute

subacute (RPGN)

chronic

Proteinuria subnephrotic

Hematuria

persistent micro

recurrent macro

Renal insufficiency

acute

chronic

Arterial hypertension

Other systems involved

Minimal change NS

FSGS

primary

secondary

Membranous nephropathy

Endocapillary GN

Crescentic GN

anti-GBM

pauci-immune

immune-complex

Membranoproliferative

immune-complex

cryoglobulin

DDD/C3 GN

paraprotein

TMA

Mesangioproliferative

IgA nephropathy

GBM abnormalities

Alport

TBMD

Pathologic accumulations

Amyloid ???

Diabetic glomerulosclerosis

Fabry

Myeloma kidney

Oxalosis

Tubular, Interstitial, Vascular injury

Idiopathic

Drugs

NSAID

Antibiotics

other

Malignancy

Carcinoma

Lymphoproliferative

other

Autoimmune

ANCA

Anti-GBM

SLE

Anti-phospholipid

RA

SS

other

Bacterial infections

Acute Streptococcal

Persistent other

Viral infections

HBV

HCV

HIV

other

Hereditary

Other kidney disease

Other disease

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