Clinical Manifestations and Treatment of HIV

Clinical Manifestations and Treatment of HIV

Ronald Mitsuyasu, MD Professor of Medicine Director, UCLA Center for Clinical AIDS Research and Education

(CARE Center)

The Natural History of HIV Infection

Pantaleo G, et al. N Engl J Med 1993;328;327.

Clinical Manifestations of HIV

? Early signs and symptoms ? Oral manifestations ? Malignancies ? Opportunistic Infections ? Neuro-psychiatric illnesses ? Women and HIV

= Not in today's presentation,

Signs and Symptoms

CDC Stage of HIV Disease

? Stage I ? Stage II ? Stage III ? Stage IV

?A ?B ?C

? C1 ? C2 ?D ?E

Acute HIV infection Asymptomatic HIV Early Symptomatic HIV Late Symptomatic HIV

Constitutional Disease Neurological Disease Secondary Infections

AIDS defining Other infections Secondary Cancers Other Conditions

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