PubMed and the Evidence-Based Universe - NNLM



PubMed and the Evidence-Based UniverseQuick QuizHow is Evidence-Based Medicine best described?Research evidence on large patient populations for producing clinical practice guidelinesA managed care organizational process setting practice standards for provider networksIntegrating the best research evidence with clinical expertise and individual patient valuesA purely statistical approach used to determine clinical decision makingA technique used by lawyers in prosecuting malpractice casesWhat components are required for a good randomized control trial?Heterogeneous patient populations, confidence intervals, multiple authorsHomogeneous patient populations, study validity measures, statistical relevanceStudy validity measures, multiple authors, identifying funding sourcesStudy validity measures, statistical relevance, multiple authorsStudy validity measures, statistical relevance, clinical significanceA study investigating an effect of a new drug for decreasing blood pressure should be a study of type:Double-blind placebo–controlled studyRetrospective cohort studyProspective case–control studyCross-sectionalInternal validity may be described as:The experiment is performed within the institutionA prospective cohort studyThe experiment uses a control groupA study is able to answer the questions it is intended to answer scientificallyExternal validity may be defined as:The study was evaluated by refereesThe study has been accepted for publicationThe results may be generalized to the entire population from which the sample was drawnThe study has been replicatedYou are investigating risk factors for a very rare disease. Which type of study you should you choose in order to obtain results most effectively and quickly?Case–control studyClinical trialCross-sectional observational studyProspective cohort studyIntention to treat may be defined as:The investigators intend to use the results of their study on a cohort of patients“Analyze where you randomize”A drug company has sponsored the studyBoth the placebo group and the interventional group took the drugRandomization is used to avoid: Selection biasConfounding variablesGeneralizationValidityWhich one of the following is the highest level of evidence? Article on a non-randomized clinical trial that includes referencesCase series article that has been peer-reviewedCochrane review Detailed report of a clinical case Which of the following statements best describes a PICO?Checklist of guidelines to assist investigators with the reporting of the findings from a meta-analysisProcess for converting a clinical problem into an answerable question that can be answered by searching for evidenceDefines a specific MeSH heading and provides synonyms covered by that headingTechnique for combining search terms in order to restrict a search to articles with specified elementsThis project has been funded in whole or in part with Federal funds from the National Library of Medicine, National Institutes of Health, Department of Health and Human Services, under Contract No. HHS-N-276-2011-00005-C with the University of Illinois at Chicago. ................
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