National PBM Monograph Template Rev20091005
Clobazam is dosed twice daily (the 5 mg dose can be administered as a single daily dose). Patients >30kg: initiate at 10 mg daily and titrate as tolerated up to 40 mg daily. Dose escalation should not proceed more rapidly than weekly, because serum concentrations of clobazam and its active metabolite require 5 and 9 days, respectively, to reach ... ................
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