Ministry of Health

3.5 Opioid Safety: Overdose, Serious Adverse Events, and Substance Misuse/Abuse. Overdose: Opioid overdose, whether intentional or unintentional, is a risk of opioid prescribing and is mainly manifested by depressed mental status, decreased respiratory rate and tidal volume, decreased bowel sounds, and pupillary constriction. Hypotension ................
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