QUICK REFERENCE TO PSYCHOTROPIC MEDICATIONS
QUICK REFERENCE TO PSYCHOTROPIC MEDICATIONS?
DEVELOPED BY JOHN PRESTON, PSY.D., ABPP
To the best of our knowledge recommended doses and side effects listed below are accurate. However, this is meant as a general reference only, and should not serve as a guideline for prescribing
of medications. Please check the manufacturer's product information sheet or the P.D.R. for any changes in dosage schedule or contraindications. (Brand names are registered trademarks.)
ANTIDEPRESSANTS
UsualSelective Action On
NAMES
Daily DosageNeurotransmitters2
Generic
Brand
Range
Sedation ACH1
NE
5-HT
DA
imipramine desipramine amitriptyline nortriptyline clomipramine trazodone nefazodone fluoxetine bupropion sertraline paroxetine venlafaxine desvenlafaxine fluvoxamine mirtazapine citalopram escitalopram duloxetine vilazodone atomoxetine vortioxetine levomilnacipran MAO INHIBITORS phenelzine tranylcypromine selegiline
Tofranil Norpramin Elavil Aventyl, Pamelor Anafranil Desyrel, Oleptro Generic Only Prozac4, Sarafem Wellbutrin4 Zoloft Paxil Effexor4 Pristiq Luvox Remeron Celexa Lexapro Cymbalta Viibryd Strattera Brintellix Fetzima
Nardil Parnate Emsam (patch)
150-300 mg 150-300 mg 150-300 mg
75-125 mg 150-250 mg 150-400 mg 100-300 mg
20-80 mg 150-400 mg
50-200 mg 20-50 mg
75-350 mg 50-400 mg 50-300 mg
15-45 mg 10-40 mg
5-20 mg 20-80 mg 10-40 mg 60-120 mg 10-20 mg 40-120 mg
30-90 mg 20-60 mg
6-12 mg
mid
mid
++
+++
0
low
low +++++
0
0
high high
++
++++
0
mid
mid
+++
++
0
high high
0
+++++
0
mid
none
0
++++
0
mid
none
0
+++
0
low
none
0
+++++
0
low
none ++
0
++
low
none
0
+++++
+
low
low
+
+++++
0
low
none +++
+++
+
low
none +++
+++
+
low
low
0
+++++
0
mid
mid
+++
+++
0
low
none
0
+++++
0
low
none
0
+++++
0
low
none +++
+++
0
low
low
0
+++++
0
low
low +++++
0
0
low
none
+
+++++
+
low
none +++
+++
0
low
none +++
+++
+++
low
none +++
+++
+++
low
none +++
+++
+++
1ACH: Anticholinergic Side Effects 2NE: Norepinephrine, 5-HT: Serotonin, DA: Dopamine (0 = no effect, + = minimal effect, +++ = moderate effect, +++++ = high effect) 3Uncertain, but likely effects 4Available in standard formulation and time release (XR, XL or CR). Prozac available in 90mg time released/weekly formulation
BIPOLAR DISORDER MEDICATIONS
NAMES
Daily
Serum1
N AMES
Generic
Brand
Dosage Range Level
Generic Brand Dosage
Daily Range
Serum1 Level
lithium carbonate olanzapine/ fluoxetine carbamazepine
Eskalith, Lithonate 600-2400
Symbyax 6/25-12/50mg4 Tegretol,Equetro 600-1600
0.6-1.5
2 4-10+
divalproex
Depakote
lamotrigine
Lamictal
oxcarbazepine Trileptal
1Lithium levels are expressed in mEq/l, carbamazepine and valproic acid levels express in mcg/ml. 2Serum monitoring may not necessary 3Not yet established 4Available in: 6/25, 6/50, 12/25, and 12/50mg formulations
750-1500 50-100
50-500
(2)
1200-2400
(2)
ANTI-OBSESSIONAL
NAMES
Generic
Brand
Dose Range1
clomipramine Anafranil
150-300 mg
fluoxetine Prozac1
20-80 mg
sertraline
Zoloft1
50-200 mg
paroxetine Paxil1 20-60 mg
fluvoxamine Luvox1
50-300 mg
citalopram Celexa1
10-40 mg
escitalopram Lexapro1
5-30 mg
vilazodone
Viibryd1
10-40 mg
1often higher doses are required to control obsessive-compulsive symptoms than the doses generally used to treat depression.
PSYCHO-STIMULANTS
NAMES
Generic
Brand
Daily Dosage1
methylphenidate methylphenidate methylphenidate methylphenidate methylphenidate methylphenidate dexmethylphenidate dextroamphetamine lisdexamphetamine d- and l-amphetamine modafinil armodafanil
Ritalin
5-50 mg
Concerta2
18-54 mg
Metadate
5-40 mg
Methylin
10-60 mg
Daytrana (patch)
15-30 mg
Quillivant XR (liquid)2 10-60 mg
Focalin
5-40 mg
Dexedrine
5-40 mg
Vyvanse
30-70 mg
Adderall
5-40 mg
Provigil, Sparlon
100-400 mg
Nuvigil
150-250 mg
1Note: Adult Doses. 2Sustained release
? Copyright 2014, John Preston, Psy.D and P.A. Distributors
ANTIPSYCHOTICS
NAMES
Generic
Brand
Dosage Range1 Sedation Ortho2
EPS3
ACH Effects4
LOW POTENCY chlorpromazine thioridazine clozapine quetiapine HIGH POTENCY perphenazine loxapine trifluoperazine fluphenazine thiothixene haloperidol pimozide risperidone paliperidone olanzapine ziprasidone iloperidone asenapine lurasidone aripiprazole
Thorazine Mellaril Clozaril Seroquel
Trilafon Loxitane Stelazine Prolixin5 Navane Haldol5 Orap Risperdal Invega Zyprexa Geodon Fanapt Saphris Latuda Abilify
50-800 mg high 150-800 mg high 300-900 mg high 150-600 mg mid
8-60 mg mid 50-250 mg low
2-40 mg low 3-45 mg low 10-60 mg low 2-40 mg low 1-10 mg low 4-16 mg low 3-12 mg low 5-20 mg mid 60-160 mg low 12-24 mg mid 10-20 mg low 40-80 mg mid 15-30mg low
high + +
high
+
high
0
mid
+/0
++++ +++++ +++++
+
mid ++++
++
mid +++
++
mid ++++
++
mid +++++
++
mid ++++
++
low +++++
+
low +++++
+
mid
+
+
mid
+
+
low
+/0
+
mid
+/0
++
mid
+
++
low
+
+
mid
+
+
low
+
+
Equivalence5
100 mg 100 mg
50 mg 50 mg
10 mg 10 mg
5 mg 2 mg 5 mg 2 mg 1-2 mg 1-2 mg 1-2 mg 1-2 mg 10 mg 1-2 mg 1-2 mg 10 mg 2 mg
1Usual daily oral dosage 2Orthostatic Hypotension Dizziness and falls 3Acute: Parkinson's, dystonias, akathisia. Does not reflect risk for tardive dyskinesia. All neuroleptics may cause tardive dyskinesia, except clozapine. 4Anticholinergic Side Effects. 5Dose required to achieve efficacy of 100 mg chlorpromazine. 6Available in time-release IM format.
ANTI-ANXIETY
Generic
NAMES Brand
Single Dose Dosage Range
BENZODIAZEPINES
diazepam
Valium
2-10 mg
chlordiazepoxide Librium
10-50 mg
clorazepate
Tranxene
3.75-15 mg
clonazepam
Klonopin
0.5-2.0 mg
lorazepam
Ativan
0.5-2.0 mg
alprazolam
Xanax, XR 0.25-2.0 mg
OTHER ANTIANXIETY AGENTS
buspirone
BuSpar
5-20 mg
gabapentin
Neurontin 200-600 mg
hydroxyzine
Atarax, Vistaril 10-50 mg
propranolol
Inderal
10-80 mg
atenolol
Tenormin
25-100 mg
guanfacine
Tenex, Intuniv 0.5-3 mg
clonidine
Catapres, Kapvay 0.1-0.3 mg
prazosin2
Minipress
5-20 mg
pregabalin
Lyrica
25-450 mg
Equivalence1
5 mg 25 mg 10 mg 0.25 mg
1 mg 0.5 mg
1Doses required to achieve efficacy of 5 mg of diazepam 2For treatment of nightmares and day time anxiety
HYPNOTICS
NAMES
Single Dose
Generic
Brand
Dosage Range
temazepam triazolam zolpidem zolpidem zaleplon eszopiclone ramelteon diphenhydramine doxepin
Restoril
15-30 mg
Halcion
0.25-0.5 mg
Ambien
5-10 mg
Intermezzo
1.75 mg
Sonata
5-10 mg
Lunesta 1-3 mg
Rozerem 4-16 mg
Benadryl
25-100 mg
Silenor 3-6 mg
OVER THE COUNTER
Name
Daily Dose
St. John's Wort1, 2
SAM-e3
Omega-34-EPA
Folic acid8
N-acetylcysteine5
Chamomile6
5-HTP7
600-1800 mg 400-1600 mg
1-2 g 500 mcg 1200-2400 mg 200-1500 mg 300-600 mg
1Treats depression and anxiety
5 For trichotillomania
2 May cause significant drug-drug interactions 6Treats anxiety:equivalent:
3Treats depression
one cup of chamomile tea
4Treats depression and bipolar disorder
7 Treats depression
8Note: available as Deplin 1-methylfolate (presctiption) 7.5-15 mg
REFERENCES and RECOMMENDED BOOKS
Handbook of Clinical Psychopharmacology For Therapists (2013) Preston, O'Neal and Talaga
Quick Reference ? Free Downloads Website: PsyD-
Clinical Psychopharmacology Made Ridiculously Simple 8th Edition (2014) Preston and Johnson
Consumer's Guide to Psychiatric Drugs Child and Adolescent
(2009) Preston, O'Neal, Talaga
Psychopharmacology
Made Simple
(2010) Preston, O'Neal, Talaga
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