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Caffeine increases the production of urine (diuresis), stimulates cardiac muscle, and relaxes smooth muscle. The liver uses xanthine oxidase, a cytochrome P450 enzyme, in its metabolism of xanthines. Such medications as allopurinol, acetaminophen (Tylenol®), warfarin (Coumadin®), and omeprazole (Prilosec®) may influence this process. ................
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