Chapter 26, Drug Therapy for Hypertension
Calcium Channel Blockers: (pregnancy category C) MOA – bind to calcium ion channels in smooth muscle and cardiac tissue ( smooth muscle relaxation & suppression of cardiac activity ( increase O2 supply and/or decrease myocardial O2 demand. Indications – HTN, angina (esp useful for variant angina); arrhythmias (diltiazem and verapamil) ................
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