Chapter 26, Drug Therapy for Hypertension
CALCIUM-CHANNEL BLOCKERS. A calcium-channel blocker, such as . verapamil, is used as an alternative to a beta-blocker to treat stable angina. Calcium-channel blockers interfere with the inward movement of calcium ions through the slow channels in heart and vascular smooth muscle cell membranes, leading to relaxation of vascular smooth muscle. ................
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