Antimicrobial Guidelines - EPUT
Acute exacerbation of COPD. NICE 12 Gold. Treat exacerbations promptly with antibiotics if purulent sputum . and. increased shortness of breath . and/or. increased sputum volume 1-3B+. Risk factors for antibiotic resistant organisms include co-morbid disease, severe COPD, frequent exacerbations, antibiotics in last 3 m 2. amoxicillin. or doxycycline. clarithromycin. If resistance: co-amoxiclav ... ................
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