Health Services Research & Development

MRI evidence of reduction of up to 40% in size of hippocampus, amygdala, thalamus, general cortical atrophy. PET and SPECT (quantifies cerebral metabolism and blood flow) can differentiate AD from other dementias; in AD, these scans show nonspecific bilateral temporoparietal hypometabolism. Pathology. Brain atrophy ................
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