Lippincott Williams & Wilkins



Supplementary materialContents:1. Acknowledgements for the Pan-Canadian Early Detection of Lung Cancer Project2. Supplementary Table S1. Unit costs1. List of acknowledged contributors to the Pan-Canadian Early Detection of Lung Cancer ProjectBritish Columbia (BC Cancer Agency & the University of British Columbia): Mark Elwood, Sharon GeeAlberta (Foothills Hospital & the University of Calgary): Rommy Koetzler Ontario (Princess Margaret Hospital, University of Toronto): Maureen McGregorOntario (Juravinski Cancer Center, McMaster University): Hamed Moazami, Kelli Kay, Elaine MooreOntario (Ottawa Hospital Regional Cancer Centre, University of Ottawa): Sharon KellyQuebec (H?pital Laval & U de Laval): Carolle St. Pierre Nova Scotia (QEII HSC, Dalhousie University): Dianna SonichsenNewfoundland (Memorial University of Newfoundland): Erin PennelThis project was funded in part by the Terry Fox Research Institute, the Canadian Partnership Against Cancer, with co-funding by the Princess Margaret Cancer Foundation Lusi Wong Fund (Toronto site). The Canadian Centre for Applied Research in Cancer Control (ARCC) is funded by the Canadian Cancer Society Research Institute.Table S1. Unit costsClassResource UnitDescriptionUnit costSub-unitSub-unit costReference or Resource Unit CodeScreening resourcesCT-S-1, CT-S-2 or CT-S-3Annual low dose screening exam, scheduled to occur annual, regardless of previous results$1931. Professional fee, radiologist, body scan-one region$88 MSP 8693a2. Professional fee, screening support$19Expert opinionb3. Procedure fee, screening spirometry interpretation$13MSP S00928 4. Spirometry equipment$25. Facility$53IHAc6. Equipment$18Siemans healthcare manufacturer’s quote (2013) and expert opinion on Canadian usage ratesdCT-S-x-FU-1,CT-S-x-FU-2 or CT-S-x-FU-3Follow-up screening LDCT exam, conducted at least 60 days before/after annual CT exam (x), and according to LDCT screening protocol$1601. Professional fee, radiologist, body scan-one region$88MSP 86932. Facility$53Same as cost component 5 and 6 in CT-S-13. Equipment$18AFB-SScreening autofluorescence bronchoscopy$7271. Procedure fee, bronchoscopy exam$88MSP S007002. Professional fee, bronchial brushings$64MSP S00736 3. Professional fee, cytology preparation and interpretation$86MSP 930954. Ambulatory hospital daycare$438OCCI: PC Z080e5. Equipment$51Expert opinionfAFB-S-biopsyScreening AFB with biopsy and without endobronchial ultrasound imaging$7821. Procedure fee, bronchoscopy with biopsy$134MSP S007022. Professional fee, bronchial brushings$64MSP S007363. Professional fee, cytology and biopsy preparation and interpretation$94MSP 930854. Ambulatory hospital day$438OCCI PC Z0805. Equipment$51Same as AFB-SDiagnostic imagingCT Non-screening CT exams, ex. regular dose CT, any CT conducted <60 days before/after screening LDCT$1601. Professional fee, radiologist, body scan-one region$88MSP 86932. Facility$53Same as CT-S-13. Equipment$18CT+Infused CT, CT conducted with the use of a contrast agent$1991. Professional fee, body scan-one region with contrast$98MSP 86942. Facility$53Same as CT-S-13. Equipment$184. Contrast agent and medical supplies$30IHAg2-CT CT exam of two regions of the body$2041. Professional fee, body scan-two regions$134MSP 086952. Facility$53Same as CT-S-13. Equipment$182-CT+CT exam of two regions of the body with the use of a contrast agent$2341-3. Same as 2-region CT$203(See 2-region CT)4. Contrast agent$30IHACT-HeadCT exam of the head$1321. Professional fee, CT head scan with contrast$62MSP 086912. Facility$53Same as CT-S-13. Equipment $18PETPositron emission tomography, FDG-PET, PET/CT, or PET$1,361Professional and technical fees$1,361MSP 9826MRIMRI exam, MRI exam of the head$2811. Professional fee and equipment$143IHAh2. Facility$138IHAUSUltrasound examination of a body region $106Professional and technical fees$106MSP 08648CXRRadiographic imaging of the chest or other body region $651. Professional fee, x-ray thoracic viscera$34MSP 88502. Facility$27IHA3. Equipment and supplies$4Expert opinioniVQSLung ventilation-perfusion scintigraphy$4451. Technical and professional fees, static lung scan$219MSP 98682. Technical and professional fees, ventilation lung scan$226MSP 9855BONESCANBone scintigraphy$225Technical and procedure fees$225MSP 9834ECHOEchocardiographic imaging$100Technical and procedure fees$100MSP 8368PYELOGRAMRadiographic imaging of the urinary system, bladder, ureters and kidneys$76Technical and procedure fees$76MSP 8591DOPP-ECHOCarotid dopplers$46Technical and professional fees$46MSP 8679Cardio/pulmonary testingPFTPulmonary function test$811. Professional fee$41MSP S009452. Technical fee$41MSP S00946PERSANTINThallium persantin scan$4231. Professional fee$22MSP S009502. Technical fee$401MSP 9854ECGElectrocardiogram$24Procedure and professional fee$24MSP 33016CORONCoronary angiography$5421. Professional fee, cardiologist$166MSP 330102. Professional fee, assistant$109MSP 8453. Procedure fee, angiography$195MSP S008414. Professional, anesthesist (30 min)$72MSP 1174PREHABDisponea clinic, pulmonary or cardiac rehabilitation$1641. Technical and professional fees, pulmonary function test$81PFT2. Professional fee, respirologist$83MSP 32012MIBICardiac perfusion scan$2201. Professional fee$191MSP 98982. Technical fee$28MSP 9897PET-CCardiac PET$1,361Same as PET$1361See PETPhysicianRESP-CRespirologist consult-detailed review$163Professional feeMSP 32010RESP-RRespirologist consult-limited review$83Professional feeMSP 32012SURG-CSurgeon-detailed review, patient present$138Professional feeMSP 70910SURG-RSurgeon-limited review, patient not present$63Professional feeMSP 79012PATH-CPathologist review-detailed $143Professional feeMSP 94010PATH-RPathologist review$79Professional feeMSP 94012CARD-CCardiologist service-detailed review, patient present$166Professional feeMSP 33010GPCGeneral physician service, patient present$80Professional feeMSP P15310ONC-COncologist service- detailed review at the start of each 6 months of clinical management$165Professional feeMSP 33510ONC-ROncologist service-limited review occurring after a within each 6 month part of clinical management following an initial consult$80Professional feeMSP 33512PATFAMPatient and family support work including social worker services, Counselor, Tobacco cessation consult$35Professional feeExpert opinionjINT-RAD Interventional radiologist service$80Professional feeMSP 83000PAT-CONFERENCEOncologist meeting to review clinical case$158Professional fee-3 oncologists3*ONC-RNEURO-CNeurologist service, detailed review, patient present$173Professional feeMSP 00410GASTRO-CGastroenterologist service, detailed review, patient present$156Professional feeMSP 33310 OTOL-COtolaryngologist service, detailed review, patient present$76Professional feeMSP 2510IMED-CInternal medicine consult, detailed review, patient present$165Professional feeMSP 00310EndoscopyEBUSEndobroncial ultrasound$12671. Procedure, endobronchial ultrasound$250MSP P107392. Procedure, biopsy brushings$65MSP S007364. Professional, cytology and biopsy preparation and interpretation$94MSP 930855. Ambulatory hospital daycare$438HOSP-DAYCARE6. Equipment$137Expert opinionk7. TBNA needle and radial tissue sampling kit$283AFBAutofluorescence bronchoscopy$727Same as screening AFB-SAFB-SAFB-BAFB-biopsy$782Same as screening AFB-S-BiopsyAFB-S-BiopsyNAV-BElectromagnetic navigational bronchoscopy$2,2601. Procedure endobronchial ultrasound$250MSP P107392. Procedure TBNA (additional)$50MSP S007033. Professional fee, cytology and biopsy preparation and interpretation$94MSP 930854. Ambulatory hospital daycare$438HOSP-DAYCARE5. Equipment$227Expert opinionl6. Disposables$1,200Expert opinionlMEDMediastinoscopy$9501. Procedure fee, mediastinoscopy$188MSP S007102. Procedure fee, percutaneous lung or mediastinal biopsy$90MSP S007393. Professional fee, cytology and biopsy preparation and interpretation$94MSP 930854. Ambulatory hospital daycare$438HOSP-DAYCARE5. Equipment$140Expert opinionmML-ENDOMicro-laryngoscopy$7221. Procedure fee, micro-laryngoscopy$175MSP 2428 2. Professional fee, cytology and biopsy preparation and interpretation$86MSP 930953. Ambulatory hospital daycare$438HOSP-DAYCARE4. Equipment$23Expert opinion DL-ENDODirect Laryngoscopy$8151. Procedure, direct laryngoscopy$125MSP 2412 2. Professional fee, cytology and biopsy preparation and interpretation$86MSP 930953. Equipment$23Expert opinion4. Ambulatory hospital daycare$438HOSP-DAYCAREPercutaneous biopsyCT-B CT-Guided biopsy$1,0541. Procedure, percutaneous lung or mediastinal biopsy$90MSP S007392. Procedure, TBNA (additional fee)$50MSP P107033. Professional, cytology and biopsy preparation and interpretation$94MSP 930854. Professional, radiology assist$108MSP S007595. Procedure, pre- and post- biopsy CT$134MSP 8695 6. Ambulatory hospital daycare$438HOSP-DAYCARE7. CT facility and equipment pre-biopsy $94See items 5 and 6 CT-S-18. CT facility and equipment post-biopsy $94US-BUltrasound-guided biopsy$6641. Procedure fee, ultrasound-guided thoracentesis$96MSP 086462. Professional fee, cytology and biopsy preparation and interpretation$94MSP 930853. Ambulatory hospital daycare$438HOSP-DAYCAREAmbulatory hospital daysHOSP-DAYCAREAmbulatory daycare, general cost for outpatient-based cancer daycare $438All non-physician costs for providing ambulatory daycare to cancer patients (including facility, nursing, administrative and technical staff, drugs) and all costs of running the hospital (finance, administration, human resources, plant ops.)$438OCCI Z080Inpatient hospital daysHOSP-VATS-WRInpatient hospital day for thoroscopic wedge resection$2,0601. Inpatient care for thoroscopic wedge resection$2,036OCCI PC: 1GR87DA2. Professional fee, surgeon hospital visit$24MSP 79008HOSP-VATS-LBInpatient hospital day for thoroscopic lobectomy$2,4841. Inpatient care for thorascopic lobectomy $2,461OCCI PC: 1GR89DA2. Professional fee, surgeon hospital visit$24MSP 79008HOSP-WRInpatient hospital day for wedge resection by open thoracotomy$2,3021. Inpatient care for wedge resection$2,279OCCI PC: 1GR87QB2. Professional fee, surgeon hospital visit$24MSP 79008HOSP-LBInpatient hospital day for lobectomy by open thoracotomy$2,4541. Inpatient care for open thoracotomy$2,430OCCI PC: 1GR89QB2. Professional fee, surgeon hospital visit$24MSP 79008HOSP-PAINInpatient hospital day for pain$1,2061. Inpatient care for pain$1,176 OCCI DC: R5292. Professional fee, oncologist hospital visit$29MSP 33508HOSP-PALLInpatient hospital day for palliative care$906Inpatient palliative care$906OCCI CMG: 810HOSP-LRInpatient hospital day for radiation to the lung$9471. Inpatient care for radiation to the lung$918OCCI PC: 1GT27JA+ DC (lung cancer)n2. Professional fee, oncologist hospital visit$29MSP 33508HOSP-BRInpatient hospital day for radiation to the brain$9041. Inpatient care for radiation to the brain $876OCCI PC: 1AN27JA+ DC (lung cancer)n2. Professional fee, oncologist hospital visit$29MSP 33508HOSP-BSInpatient hospital day for brain surgery$1,4411. Inpatient care for brain surgery$1,402 OCCI PC: 1AN87SZGX2. Professional fee, neurologist hospital visit$39MSP 00408HOSP-PNMInpatient hospital day for pneumonia$1,4531. Inpatient care for pneumonia $1,370 OCCI DC: R532. Professional fee, respirologist hospital visit$42MSP 32008HOSP-DEMInpatient hospital day for dementia$6971. Inpatient care for dementia $670OCCI DC: F032. Professional fee, geriatrics$73MSP 33412HOSP-ARDSInpatient hospital day for acute respiratory distress syndrome$2,9961. Inpatient care for acute respiratory distress $2,955OCCI DC: J802. Professional fee, respirologist hospital visit$42MSP 32008HOSP-MIHospital day for myocardial infarction$2,2181. Inpatient care, myocardial infarction$2,184OCCI DC 12192. Professional fee, cardiologist hospital visit$34MSP 33008HOSP-PEHospital day for pulmonary embolism$1,2621. Inpatient care for pulmonary embolism$1,220OCCI: DC I2692. Professional fee, respirologist hospital visit$42MSP 32008HOSP-HFHospital day for heart failure$1,4431. Inpatient care for heart failure$1,409OCCI DC 15002. Professional fee, cardiologist hospital visit$34MSP 33008HOSP-NEUHospital day for neutropenia$1, 2111. Inpatient care for neutropenia$1,182OCCI DC 7002. Professional fee, oncologist hospital visit$29MSP 33508HOSP-PNXInpatient hospital day for resolution of pneumothorax$1,0691. Inpatient care for pneumothorax $1,028OCCI PC: 95802. Professional fee, respirologist hospital visit$42MSP 32008Inpatient hospital days-critical careHOSP-ICU-1First day in intensive care unit (ICU)$4,1251. ICU acute inpatient care$2,954OCCI DC: J802. Professional fees-adult critical care, first day$332MSP 014113. Professional fees-ventilator support, first day$289MSP 014124. Professional fees-comprehensive care, first day$550MSP 01413HOSP-ICU-SUBAny subsequent day in ICU$3,5521. ICU acute inpatient care$2,954OCCI DC: J802. Professional fees-adult critical care, days 2-7$169MSP 014213. Professional fees-ventilator support, days 2-7$147MSP 014224. Professional fees-comprehensive care, days 2-7 $252MSP 014223Hospital day-acute careHOSP-ER-CPEmergency room admission for chest pain$5561. Emergency room admission for chest pain$429OCCI DC: R0742. Professional fee emergency room physician$128MSP 1810HOSP-ER-PNMEmergency room admission for pneumonia$4971. Emergency room admission for pneumonia $369OCCI DC: J1892. Professional fee-emergency room physician $128MSP 1810HOSP-ER-MFEmergency room admission for malaise and fatigue$4441. Emergency room care for malaise and fatigue$316OCCI DC: R0532. Professional fee-emergency room physician $128MSP 1810HOSP-ER-SOBEmergency room admission for shortness of breath$4981. Emergency room care for shortness of breath$370OCCI DC: R0602. Professional fee-emergency room physician $128MSP 1810HOSP-ER-NEUEmergency room admission for neutropenia$6261. Acute care for neutropenia$498OCCI DC: D7002. Professional fee-emergency room physician $128MSP 1810HOSP-ER-PNXEmergency room admission for pneumothorax$4961. Acute care for pneumothorax$369OCCI DC: J95802. Professional fee-emergency room physician$128MSP 1810Hospitalization case mix groupsHospitalization to enable acquisition of a screening LDCT-exam resultCase mix groupo for hospitalizations required in order to obtain a screening image (n<5)$9,088 (FOI)pInpatient hospital day for pneumothorax$1,111HOSP-PNXHospitalizations for progressive lung cancerCase mix groupo for hospitalizations for progressive disease (n=20)$18,494 (3,501)Inpatient hospital day for palliative careHOSP-PALLInpatient hospital day for pain-unspecifiedHOSP-PAINInpatient hospital day for brain radiationHOSP-BRInpatient hospital day for lung radiationHOSP-LRInpatient hospital day for brain surgeryHOSP-BSEmergency care for malaise and fatigueHOSP-ER-MFInpatient hospital day for pneumoniaHOSP-PNMSurgical proceduresWRWedge resection$1,5891. Procedure, wedge resection$1,307MSP 790302. Professional, laboratory medicine$143MSP 940123. Professional, surgeon report$139MSP 930954. Professional, anesthesist (2.5h)$428MSP 01178LBLobectomy or segmental resection greater than a wedge resection$1,5891. Procedure, lobectomy$1,307MSP 790152. Professional, laboratory medicine$143MSP 940103. Professional, surgeon report$139MSP 930954. Professional, anesthesist (2.5h)$428MSP 01178SECTION+1Wedge resection with completion lobectomy, bi-lobectomy, or removal of any first additional segment of lung$8761. Procedure, additional section$733MSP 790352. Professional, laboratory medicine$143MSP 94010SECTION+2Any subsequent segment of lung removed after SECTION+1$2181. Procedure, additional wedge resection of lung$75MSP 790362. Professional, laboratory medicine$143MSP 94010SPEC+Surgical specimen submitted for pathology in addition to resected specimen. Ex: nodal sampling, pleural biopsy, frozen sections for re-submission$791. Professional, cytology and biopsy preparation and interpretation$79MSP 93085FIST-CClosure of Bronchial pleural fistula$1,1651. Procedure fee, close fistula$913MSP 790802. Professional fee, anesthesist (2h)$370MSP 01180CRN-XCraniotomy$1,9511. Procedure fee, craniotomy$1,699MSP 031292. Professional, laboratory medicine$143MSP 940103. Professional, surgeon report$139MSP 930954. Professional fee, anesthesist (5h)$857MSP 01178Surgery case mix groupingTHOROCOTOMYMean per-person cost of case mix groupo for open throcotomy including wedge resection, lobectomy, wedge resection with lobectomy (n=30)$18,186(952)1. Procedure, lobectomy or wedge resectionWR or LB2. Procedures, additional sectionsWR+LB3. Inpatient day, thoracotomy, open approachHOSP-LB4. Inpatient day for wedge resection, open approachHOSP-WR5. Professional fee, interventional radiologist (if microcoil-guided)IRCTHOROSCOPIC RESECTIONMean per-person cost of case mix groupo for thoroscopic wedge resection, lobectomy, and wedge resection with lobectomy (n=48)$16,361 (1,234)1. Procedures, lobectomy or wedge resectionWR or LB2. Procedures, additional sectionsSECTION+1, +23. Inpatient care for thoroscopic lobectomy HOSP-VATS-LB4. Inpatient care for thoroscopic wedge resection (per diem)HOSP-VATS-WR5. Professional fee, interventional radiologist (if microcoil-guided)IRCBIOLOBECTOMYMean per-person cost of case mix groupo of bilobectomy (N<5)$26,765 (FOI)p1. Procedure, lobectomy with additional segmentWR+LB2. Inpatient hospital day-open thoracotomyHOSP-LBChemotherapy/radiotherapy resourcesCARBOPLATINMean per-person drug cost of case mix groupo of carboplatin use per-course of chemotherapy. (n= 7)$152 (28)Drug cost *dose/AUC*((GFRq)+25)*doses/cycle*#cycles completed in courseoBCCA pharmacy databaser ETOPOSIDEMean per-person drug cost of case mix groupo of etoposide use per-course of chemotherapy. (n=12)$462 (62)Drug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in courseoPEMETREXEDMean per-person drug cost of case mix groupo of pemetrexed use per-course of chemotherapy (n<5)$23,702 (FOI) pDrug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in coursePACLITAXELMean per-person drug cost of case mix groupo of paclitaxel use per-course of chemotherapy (n<5)$245 (FOI) pDrug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in courseVINORELBINEMean per-person drug cost of case mix groupo of vinorelbine use per-course of chemotherapy (n=9)$358 (42)Drug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in courseCISPLATINMean per-person drug cost of case mix groupo of cisplatin use per-course of chemotherapy (n=19)$116 (13)Drug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in courseTOPOTECANMean per-person drug cost of case mix groupo of topotecan use per-course of chemotherapy (n<5)$638 (FOI) pDrug cost*(dose/BSA)*BSA* doses/cycle*#cycles completed in courseCLINICAL-RXAny non-chemotherapy regimen drug or clinical trial drug $0Assume zero cost$0Stated assumptionCHEMO-DAYCAREDaycare cost for IV administration of chemotherapy drugs$438Ambulatory daycare for administration of IV chemotherapy$438HOSP-DAYCAREEGFREGFR mutations$243PCR based analysis of EGFR mutations$243Behl et al 2012sRFRadiotherapy fraction$425Ambulatory daycare and administration of radiotherapy$425OCCI PC: 1GT27JARBC1 unit packed Red blood cells for transfusion$3951. Blood product $211Applied health economics and health policy (9) 1, 2011 t 2. Leukocyte reduction$303. Irradiation$354. Screening$505. Storage and retrieval$68Case mix group for chemotherapy/radiotherapy course of treatmentRTRadiation therapy, case mix groupo, mean per-person cost per course (n=27)$5,427 (1,048)See RF$425CHEMO/RADMean per-person treatment cost for case mix groupo of each course of outpatient chemotherapy and/or radiotherapy (n=46)$8,096 (1,514)Patient-level composite of drugs, administration and radiotherapy per course of treatmentCARBOPLATINETOPOSIDEPEMETREXEDPACLITAXELVINORELBINECISPLATINTOPOTECANCLINICAL-RXHOSP-DAYCARERFCase mix group for minor complicationsCOMP-MI-PNEUMOTHORAXMean per-person cost of case mix groupo for pneumothorax after CT-B requiring observation within 48 hours of procedure(n=5) $306 (74)1. Acute care of pneumothorax HOSP-ER-PNX 2. Chest radiographyCXRCOMP-MI-SOBMean per-person cost of case mix groupo for minor complications including: emergency admission to hospital within 48 hours of procedure, or Hematoma-trauma to vocal chords from AFB procedure (n<5) $597 (FOI) pEmergency care for shortness of breathHOSP-ER-SOB2 Emergency care for chest painHOSP-ER-CP3. Emergency care for general malaise and fatigueHOSP-ER MF4. Microlaryngoscopy ML-ENDO5. Otolaryngologist consult OTOL-CCase mix group for intermediatecomplicationsCOMP-I-PNEUMOTHORAXMean per-person cost of case mix groupo for pneumothorax requiring chest tube insertion(n=10)$2,928 (1,013)1. Procedure, pneumothorax$37MSP S079242. Professional fee, interventional radiologist$80MSP 83003. Professional fee, anesthesia (30min)$36MSP 11744. Inpatient hospital day for pneumothorax HOSP-PNX5. Chest X-rayCXR6. CT scan for pneumothoraxCT7. CT with contrast for pneumothoraxCT+COMP-I-INFECTIONMean per-person cost of case mix groupo pneumonia within 24 hours of bronchoscopy or 30 days of surgery, and febrile neutropenia requiring antibiotics or hospital admission (n=9)$6,613 (2,050)1. Emergency care of pneumonia HOSP-ER-PNM2. Inpatient day for pneumoniaHOSP-PNM3. Inpatient care for neutropeniaHOSP-NEU4. Emergency care of neutropeniaHOSP-ER-NEUCase mix group for serious complicationsCOMP-S-ICUMean per-person cost of case mix groupo for any ICU admission within 30 days of surgery or during chemotherapy, not resulting from another complication (n=7)$8,654 (1,266)1. Inpatient care in ICU 1st dayHOSP-ICU-12. Inpatient care in ICU, subsequent dayHOSP-ICU-SUBCOMP-S-CHEMOMean per-person cost of case mix groupo for any serious complications arising from chemotherapy/radiotherapy including: admittable neutropenia requiring blood transfusion support, pulmonary embolism or heart failure during chemotherapy (n=5)$4,193 (1,707)1. Acute inpatient care for congestive heart failureHOSP-HF2. Emergency care of neutropeniaHOSP-ER-NEU3. Inpatient care for neutropeniaHOSP-NEU4. Inpatient care for pulmonary embolismHOSP-PE5. Emergency care for chest painHOSP-ER-CP6. Red blood cells, 1 unitRBCCOMP-S-SURGMean per-person cost of case mix groupo for any for any serious complications arising from surgery including: Myocardial infarction, dementia preventing discharge, broncho-pleural fistula (BPF) or acute respiratory distress syndrome (ARDS) within 7 days of surgery (n=7)$35, 844 (17,829)1. Inpatient hospital day for myocardial infarctionHOSP-MI2. Inpatient hospital day for dementiaHOSP-DEM3. Inpatient hospital day for BPFHOSP-BPF4. Inpatient hospital day for ARDSHOSP-ARDS5. Procedure, close BPFFIST-CaMedical service plan of British Columbia, (MSP, medical reimbursement for residents of British Columbia) schedule of fees available at ()bScreening navigator: 5 minute telephone service for 2.8 people interviewed/person enrolled+25 minute telephone or clinic interview for each person enrolledcFacility fees based on radiology service fees from the Interior Health Authority in the province of British Columbia (IHA) 2010 and includes: clerical and technologist wages, transcription, laundry, housekeeping, IMIT, plant, PACs, licensing and storaged$861,252 CT scanner depreciated over 5 years serving 9600 users per yeareOntario Case Costing initiative for hospital costs in the province of Ontario (OCCI) costing analytical tool using search terms: year 2010/2011, age group 18-69, and diagnostic codes (DC), procedural codes (PC) or case mix group (CMG) as specifiedf70,000 bronchoscopy equipment, depreciated/5 year, 600 users per year estimated usage rate: Hergott CA, et al. Repair Costs for Endobroncial Ultrasound Bronchoscopes. Journal of Bronchology and Interventional Pulmonology. 2010;17(3):223-7gFees for contrast and medical supplies for CT scan from IHA radiology service fees 2010hMRI service fees from IHA radiology service fees 2010i$23,000 X-ray machine, depreciated/5 years; 10,000 users/yearjWages and benefits for social worker in British Columbia in 2013 @ $35/hourkEBUS equipment $137,000 capital cost depreciated/5 years serving 250 users per year, $283 disposables per use lNavigational bronchoscopy equipment $100, 000 capital cost depreciated/5 years serving 100 users per yearmEndoscope equipment-$70,000 capital cost, depreciated/5 years, serving 100 users per yearn OCCI search terms modified to include only lung cancer cases (i.e.: diagnostic codes: C33,C3400,C3401,C3409,C3410,C3411,C3419,C342,C3430,C3431,C3439,C3480,C3481,C3489,C3490,C3491,C3499)o Case mix group calculations include all cases in a common hospitalization group with listed subunit costs applied when applicablep FOI=Freedom of information. Numbers reported here are aggregated to protect patient confidentiality and when less than 5 individuals used the resource, the standard error was not reportedqGFR=((N*(140-age))*weight in kg/serum creatine ?mol/l; N=1.135, average serum creatine=76.25?mol/l, age of lung cancer patient=63, weight in kg=76, BSA=Body surface area=1.7m3rUse of drug cost data from the BCCA database requires adherence to an agreement of confidentiality between the agency and drug manufacturers for which the exact unit cost must not be released as a disaggregated unitsBehl A.S., et al. Cost-Effectiveness of screening for KRAS and BRAF mutaitons in Metastatic Colorectal Cancer. Journal of the National Cancer Institute. 2012; 104 (23): 1785-95tToner, R.W., et al. Costs to Hospitals of Acquiring and Processing Blood in the US. Applied Health Economics and Health Policy. 2011; 1 (9): 29-37 ................
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