New Zealand Practice Guidelines for Opioid Substitution ...
12.2 Protocol – designation of specialist services 83. 12.3 Protocol – designation of lead clinicians 84. ... Day of induction COWS 8 (moderate to severe withdrawal) 1 2–4 mg + 0–4 mg 1–2 hours later if necessary 8 mg 2 Increase by 2, 4 or 8 mg; maximum dose 16 mg 3 Increase by 2, 4 or 8 mg; maximum dose 24 ... ................
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