Two age peaks in the incidence of chronic fatigue syndrome ...
A moderate-quality RCT (score = 7.5/11) compared titrated doses of tramadol (1-2 50mg tablets QID) vs. placebo for treatment of 129 patients with knee osteoarthrosis (Fleischmann 2001). The study included a washout period and 91 days of treatment. Pain intensity scores were tramadol (2.10±1.06) vs. placebo (2.48±1.13), p = 0.082. ................
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