1 The Neridronate Treatment.

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The Neridronate Treatment.

DISCOVER THE PATENTED PROTOCOL DESIGNED FOR CRPS THAT BROUGHT HUNDREDS OF PATIENTS IN REMISSION.

First and foremost, the

FACT

Bisphosphonates and CRPS.

ABSTRACT: Neridronate is an amino-bisphosphonate that has been officially approved as a treatment for osteogenesis imperfecta, Paget's disease of bone and complex regional pain syndrome (CRPS) in Italy. Neridronate is administered either intravenously or intramuscularly; thus, it represents a valid option for both cases with contraindications to the use of oral bisphosphonates and cases with contraindications or an inability to receive an intravenous administration of these drugs. Furthermore, although the official authorized use of neridronate is limited to only 3 bone diseases, many experimental and clinical studies support the rationale for its use and provide evidence of its effectiveness in other pathologic bone conditions that are characterized by altered bone remodeling.

Internationally, Neridronic acid is the first investigational medicine to receive Breakthrough Therapy Designation for the treatment of CRPS. It was discovered and developed by Abiogen Pharma SPA, Pisa, Italy, where it was patented and recognized by AIFA as the approved therapy for CRPS.

Before and after pictures of Carole's hand.

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Carol was treated for CRPS which affected her left hand causing extreme swelling, pain, burning flares and inability to move the hand. Five months after the treatment, she regained mobility and eventually her hand went perfectly back to normal.

See here incredible testimony at truth-forneridronate

S.

Trial's results

"Neridronate has also been evaluated as a treatment for

CRPS-I in a recent large multicentre, randomized, double-

blind, placebo-controlled trial. About 82 patients with CRPS-I

in either their hand or foot were randomly assigned to receive

either an intravenous infusion of 100 mg of neridronate every

3

3 days for a total of 4 times or the placebo. After 50 days

of the last infusion, the placebo group was treated with the

same regimen of neridronate. In the double-blind phase, the

visual analog scale (VAS) for pain was significantly lower in

the neridronate-treated group after 20 days of treatment

than in the placebo group and only continued to decrease

for the next 20 days in the neridronate group. Oedema, pain

induced by passive motion, allodynia, and hyperalgesia were

significantly reduced in patients who were treated with

neridronate compared with those in patients in the placebo

group, and various functional indexes were increased. All

neridronate-treated patients and only 45% of the patients who

were treated with the placebo discontinued the symptomatic

drugs within 2 weeks. The results obtained from patients

had previously received the placebo, were subsequently

treated with neridronate during the open-extension phase,

and were similar to obtained from the neridronate-treated

group during the blind phase, as represented by significant

reductions in the VAS, oedema, and pain on passive motion;

the disappearance of allodynia and hyperalgesia; and an

improvement in functional scores after 40 days of follow-up. A

complete normalization of the abnormal uptake was reported

in patients undergoing bone scintigraphy, and a disappearance

of localized bone oedema was observed on MRIs from 12

treated patients"

Corrado, A., Colia, R. and Cantatore, F. P. (2017) `Neridronate: From Experimental Data to Clinical Use', Clinical Medicine Insights: Therapeutics. doi: 10.1177/1179559X17732971.

How does it work?

CRPS Treatment is a Division of Medical Tourism Italy. The process is therefor the same for the general Medical Tourism Italy patient; each online consultation and contact with our Personal Health Planner is completely free of charge, and you'll get all the information you need to plan your therapy trail accordingly to your needs. After you're settled with the kind of package you'd like to book, the hospitality solution that works best for you and all the details about your stay, the only thing you have to take care of on your own is booking the flights. We choose to work this way in the Patient's interest.

We know that getting the best treatment abroad for your condition is expensive, and we want our patients to be able to save as much as possible if they so wish; as the plane fares are something constatly changing, we let our patients choose which airline to get and to which airport to arrive to (Verona, Treviso or Venice). From there on, we'll take care of everything.

The Personal Health Planner will come and pick you up at the Airport, escort you to your Hotel, make sure that everything is up to your liking, drive you wherever you need to go, they will come with you to the therapies and hospital visits and you'll not be left alone; the Personal Health Planner will be your interpreter throughout all your stay and even afterwards for a 6 months Followup included in the price.

For the CRPS Treatment specificially, the procedure is as follow:

? Visit in the Hospital with the CRPS Specialist

? Administering of the I.V. infusions of Neridronate

? Administering if needed of the pain medications

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? Rehabilitaition and Physical Therapy with the designed specialist

? Rest and Recovery

? Tourism with the Personal Health Planner, if you so wish

? Light Therapy with Bioptron technology

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What is the Treatment's Success Rate?

Depending on how quickly the Treatment is administered after the disease's start point, the success percentage is 95% or higher, depending also on the singular Patient's History with Chronic Pain. If CRPS has been running since more than 4 years, however, there still will be a remarkable improvement of the quality of life of the Patient, but the chances of getting to full remission might be compromised. The patient will still get a partial remission, being able to go back to a lifestyle which is not merely centered on the pain management. Most of our patients have been able to go back to work, doing house chores, driving, swimming, writing and all those activities part of the ordinary life they missed.

Your Personal Health Planner!

The Personal Health Planner is our Company's core asset; an experienced, empathic consultant that will be in charge of your Treatment Plan. This grants you the advantage in handling your health in a unique way, with a dedicated and 24/7 focus on your best interest only, selecting and tailoring your therapeutic path to reach the best outcome for your specific case. This is where traditional healthcare tends to fail. When you find the right medic, you are more than likely to be left alone afterwards in discovering how much additional care and therapy is needed for a full recovery. That's how we're different. We are interested in delivering full recovery, customized on your story and needs.

Diego Alfredo Gonzales Personal Health Planner

Emilie Rigaud Personal Health Planner

Allowing your body to heal.

For a successful healing, especially when the Nervous

System and reumathic pathologies are involved, it is

extremely important not feel stressed. It has been

shown through scientific research how stress can

weaken the immune system and slow down recovery,

if not completely empare it. That's why Medical

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Tourism Italy also take care of all the particularities

of your journey and stay, from the small details, to

the most important bureaucratic process handling.

You can choose among several Hotel classes equipped

with the latest technologies and comforts, specifically

designed for patients and people dealing with Chronic

Pain or Recovery Time. We also believe in the Mind over

Body approach and we provide several possibilities to

enjoy a revolutionary concept of Tourism, based on

experiences that will allow you to explore the Italian

culture your own way, at your own pace.

Federica Fontana Personal Health Planner

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Extinguishing CRPS Pain. One drop at a time.

Why are Social Media so important for us?

The main reason why we ask our Patients the Communities online, and we would

to sign a privacy release form, is that we prefer Warriors to use their own voices,

have very limited means to distribute the tell their own stories, let their brothers

informations across the web. We don't

and sisters know what's the truth about

want to start aggressive and targeted

Medical Tourism Italy and what ware we

advertising campaigns; that would blur trying to achieve here. We strive to be

our goal which is not to simply convert always present online and be available

sales, but to actually help people. That's for you at any time, even out of business

why our online consulting is always free hours; to us, also this means having a

of charge. We know how much Warriors 100% Patient Centered Approach.

have found great use and comfort from

We are

A Patient - Health Planner bond

Crossing the Oceans or the country to

the Patients and their Personal Health

get the Treatment you need can be very Planners is something truly honest and

scary. That is also why the Personal

incredibly powerful, leading the patient

Health Planner is one of our main asset. towards a greater degree of confidence

It's a completely new kind of figure,

and relaxation, which are fundamental

designed as a job role especially for

part of healing and recovery. That is

accomplishing our mission. We selected also why being a big Community is so

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as Personal Health Planners only

important to us, as it is almost like

extremely emphatic people, completely being a big family. With this idea in mind,

and reliably bilingual, who have been

we have created the CRPS, Neridronate

specifically trained to be able to assist Treatment Italy: Support Group. With its

the Patient in a 360? spectrum of needs growing number it's counting in August

and expectations. At first it might feel

2019 more than 900 members, and it's

awkward or very new, the idea of having were our past Patients and new one

a person you don't know yet who will

can share their experiences and stay in

always be by your side. Instead, we

touch.

have witnessed how the bond between

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