Cyst Fluid Glucose is Rapidly Feasible and Accurate in ...
nature publishing group
ORIGINAL CONTRIBUTIONS
1
Cyst Fluid Glucose is Rapidly Feasible and Accurate in
Diagnosing Mucinous Pancreatic Cysts
Thomas Zikos, MD1, Kimberly Pham, BS1, Raf?ck Bowen, PhD, MHA2, Ann M. Chen, MD1, Subhas Banerjee, MD1, Shai Friedland, MD, MS1,
Monica M. Dua, MD3, Jeffrey A. Norton, MD3, George A. Poultsides, MD3, Brendan C. Visser, MD3 and Walter G. Park, MD, MS1
OBJECTIVES:
Better diagnostic tools are needed to differentiate pancreatic cyst subtypes. A previous metabolomic
study showed cyst ?uid glucose as a potential marker to differentiate mucinous from non-mucinous
pancreatic cysts. This study seeks to validate these earlier ?ndings using a standard laboratory
glucose assay, a glucometer, and a glucose reagent strip.
METHODS:
Using an IRB-approved prospectively collected bio-repository, 65 pancreatic cyst ?uid samples
(42 mucinous and 23 non-mucinous) with histological correlation were analyzed.
RESULTS:
Median laboratory glucose, glucometer glucose, and percent reagent strip positive were lower in
mucinous vs. non-mucinous cysts (P ................
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