ICU SEDATION GUIDELINES

However, the effects of DDAVP do not last more than 24 hours and patients are likely to develop tachyphylaxis after a single dose of DDAVP limiting its utility for repeated dosing (20). There have been two randomized, double-blind, placebo controlled trials using DDAVP (either 0.3 mcg/kg/dose or 0.4 mcg/kg/dose) for the treatment of uremic ... ................
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