Pathology of the EndometriumPathology of the Endometrium

Management of SIL

Thomas C. Wright, Jr.

Pathology of the Endometrium

Thomas C. Wright

Columbia University, New York, NY

Changes in the

Uterus

Thoughout

Th

h t lif

life

there are marked

changes in the

size of the uterus

Page # 1

Management of SIL

Thomas C. Wright, Jr.

Endometrium

Most common diseases:

Abnormal uterine bleeding

Inflammatory conditions

Benign neoplasms

Endometrial cancer

Anatomical Regions

C

Corpus:

Responsive

R

i tto h

hormones

Thickness changes with

cycle

LUS:

Thinner than corpus

Less hormonally

responsive Hybrid between

endocervix and endometrium

Page # 2

Management of SIL

Thomas C. Wright, Jr.

Changes in the

Uterus

Thoughout

Th

h t lif

life

there are marked

changes in the

size of the uterus

Cellular Components

Epithelium:

Basalis-type cell

Secretory cells

Ciliated cells

Stroma:

Stromal cells

Stromal granulocytes

Page # 3

Management of SIL

Thomas C. Wright, Jr.

Endometrium

Composed of both

glandular and stromal

elements

Cyclical Changes in the Endometrium

Page # 4

Management of SIL

Thomas C. Wright, Jr.

Cyclical Changes in the Endometrium

Early

Proliferative

Phase

Small circular glands

with numerous

mitoses are present.

Page # 5

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