Pathology of the EndometriumPathology of the Endometrium
Management of SIL
Thomas C. Wright, Jr.
Pathology of the Endometrium
Thomas C. Wright
Columbia University, New York, NY
Changes in the
Uterus
Thoughout
Th
h t lif
life
there are marked
changes in the
size of the uterus
Page # 1
Management of SIL
Thomas C. Wright, Jr.
Endometrium
Most common diseases:
Abnormal uterine bleeding
Inflammatory conditions
Benign neoplasms
Endometrial cancer
Anatomical Regions
C
Corpus:
Responsive
R
i tto h
hormones
Thickness changes with
cycle
LUS:
Thinner than corpus
Less hormonally
responsive Hybrid between
endocervix and endometrium
Page # 2
Management of SIL
Thomas C. Wright, Jr.
Changes in the
Uterus
Thoughout
Th
h t lif
life
there are marked
changes in the
size of the uterus
Cellular Components
Epithelium:
Basalis-type cell
Secretory cells
Ciliated cells
Stroma:
Stromal cells
Stromal granulocytes
Page # 3
Management of SIL
Thomas C. Wright, Jr.
Endometrium
Composed of both
glandular and stromal
elements
Cyclical Changes in the Endometrium
Page # 4
Management of SIL
Thomas C. Wright, Jr.
Cyclical Changes in the Endometrium
Early
Proliferative
Phase
Small circular glands
with numerous
mitoses are present.
Page # 5
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