GEORGIA BAPTIST COLLEGE OF NURSING



GEORGIA BAPTIST COLLEGE OF NURSING

OF

MERCER UNIVERSITY

NUR 312 Pharmacology in Nursing II

Unit II: Drugs That Affect Physical Regulation: Hormonal

Lesson Objectives: At the completion of this lesson, the student will:

1. Identify clinical manifestations caused by deficiency or overactivity of the

1. endocrine system.

2.

2. Describe the classification of hormonal agents.

3. Describe the pharmacokinetics and pharmacodynamics of the steroid and

protein hormonal agents.

4. Discuss the therapeutic use of hormonal agents and hormone antagonists.

5. Differentiate the side effects and adverse reactions associated with use of

selected hormonal agents.

6. Correlate use of specific hormonal agents with clinical manifestations.

7. Discuss hormonal agents used in health care of women across the life span.

8. Utilize the nursing process to identify specific nursing considerations and

the plan of care for individuals receiving hormonal agents.

Content Outline:

1. Review of endocrine anatomy and physiology and pathophysiology

1.1. Pituitary (anterior and posterior)

2. Thyroid and Parathyroid

2. Adrenal medulla and cortex

1.4. Pancreas

5. Ovary and Testes

2. Anterior pituitary hormonal agent(s): Dynamics/Kinetics, Therapeutics,

Side Effects/Adverse Reactions, and Nursing Considerations

1. Growth hormone

2.1.1Somatropin (Humatrope)

2.1.2. Somatrem (Protropin)

3. Posterior pituitary hormones: Dynamics/Kinetics, Therapeutics,

Side Effects/Adverse Reactions, and Nursing Considerations

3.1. Antidiuretic hormone (ADH)

3.1.1. Vasopressin

3.1.2. Desmopressin Acetate (DDAVP)

3.2. Oxytocin

3.2.2. Oxytocin (Pitocin)

3.2.3. Ergonovine (Ergotrate)

4. Thyroid hormones and anti-thyroid agents: Dynamics/Kinetics,

Therapeutics, Side Effects/Adverse Reactions, and Nursing

Considerations

4.1. Thyroid hormones

4.1.1. Levothyroxine Sodium (Synthroid)

4.1.2. Thyroglobulin Sodium (Proloid)

4.1.3. Liothyronine (Cytomel)

4.2 Anti-thyroid agents

4.2.1. Methmazole (Tapazole)

4.2.2. Propythiouracil (PTU)

4.2.3. Iodine (PI)

5. Parathyroid drugs: Dynamics/Kinetics, Therapeutics, Side Effects/

Adverse Reactions, and Nursing Considerations

1. Calcium salts (Os Cal)

2. Calcitonin

6. Adrenocortical Steroid Agents: Dynamics, Therapeutics, Side Effects/

Adverse Reactions, and Nursing Considerations

1. Glucocorticoid

6.1.1. Prednisone

6.1.1. Cortisone (Cortone)

6.1.2. Dexamethasone (Decadron)

6.2. Adrenal Steroid Inhibitors

6.2.1. Aminoglutehimide (Cytodren)

2. Trilostan (Modrastane)

7. Hypoglycemic and hyperglycemic agents: Dynamics, Therapeutics, Side

Effects/Adverse Reactions, and Nursing Considerations

7.1 Oral Hypoglycemics

7.1.1 Sulfonyureas

7.1.1.1.Diabeta

2. Biguanides

7.1.2.1Prandin

3. Alpha-glucosidase Inhibitors

7.1.3.1 Precose

7.1.4 Thiazolidinediones

7.1.4.1 Avandia

7.2. Insulin

1. Regular(Humalin R) short acting

2. Insulin Lispro (Humalog) rapid acting

3. Isophane (NPH) intermediate acting

4. Glargine (Lantus) long acting

5. combination (Novalin 70/30)

2. Glucose Elevating Agents

7.3.1. Glucagon

7.3.2. Glucose (Glutose, Insta Glucose)

8. Estrogens, progestin and oral contraceptives: Dynamics, Therapeutics,

Side Effects/Adverse Reactions, and Nursing Considerations

8.1. Estrogen

8.1.1. Estrogen (Premarin)

8.1.2. Estradiset (Estrace, Transderm, Estraderm)

8.2 Progestins

8.2.1. Progestin (Proviral)

8.2.2. Medroxyprogesterone acetate (Depo-Provera)

9. Androgens and anabolic steroids: Dynamics, Therapeutics, Side Effects/

Adverse Reactions, and Nursing Considerations

9.1. Testosterone (Depo-testosterone)

2. Methyltestosterone (Testex, Android)

Teaching/Learning Activities:

1. Lecture with discussion

2. Handouts

3. Selected media

Critical Thinking Focus:

Discuss the implications of hormone replacement therapy (HRT) in perimenopausal & menopausal women.

Required Reading:

Aschenbrenner,D.S., Cleveland, L., & Venable,L.J., & (2002). Drug therapy

in nursing. (pp. 721-758;759-781;782-817;818-835;836-856;857-874).

Philadelphia: Lippincott

8-04 LC

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