Formulation and Characterization of Nasal Sprays

Butorphanol nasal spray* Desmopressin nasal spray' pH Osmolality(mOsmol/Kg) or Osmolarity (mOsmol/L) 57 Not available 5.5 372 or 742 rnOsrnol/Kg for 5 or 20 mg dose respecfively 5 3.5-6 420-470 rnOsrn01/L Not available Not available 10 JUNE 2012 Formulation and characterization of nasal sprays An examination of nasal spray form ulafion ................
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