Chapter 16: DNA: The Genetic Material
they present special problems for DNA replication: the 5’ end RNA primer cannot be replaced with DNA, creating 5’ end gaps. this leads to shorting of chromosomes at the ends with each cell generation. in some cells, special telomerase enzymes can generate longer telomeres – telomerase is required in germ-line cells, and active in cancer cells as well. DNA packaging in chromosomes. the ... ................
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