Agonist & Antagonist Actions
In addition to muscarinic, H1, 5-HT. 3 and NK 1. receptor antagonists, and glucocorticoids, three chemical classes of D2 (dopamine) receptor antagonists are used. The phenothiazines, exemplified by prochlorperazine (Compazine®), and the butyrophenones, exemplified by . droperidol (Inapsine®), act primarily by blocking dopamine signals in the CTZ. ................
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