ANTIDEPRESSANT AGENTS - DrofRx
1. Traditional: block dopamine receptors. 2. Atypical: block serotonin receptors (has less extrapyramidal effects) MOA: 1. Dopamine receptor blocking activity in brain. D1, D5. activate adenylyl cyclase. D2, D3, D4. inhibit adenylyl cyclase (D2. correlates to efficacy of neuroleptic) 2. Serotonin receptor blocking activity in brain. S2 ................
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