Express Scripts 2020 National Preferred Formulary Exclusions
2024 National Preferred Formulary Exclusions
The excluded medications shown below are not covered on the Express Scripts drug list. If you're currently using one of the excluded medications, please ask your doctor to consider writing you a new prescription for one of the following preferred alternatives. Additional covered alternatives may be available. Costs for covered alternatives may vary. Not all the drugs listed are covered by all prescription plans; check your benefit materials for the specific drugs covered and the copayments for your plan. For specific questions about your coverage, please call the number on your member ID card. If there is a clinical reason, identified by your doctor, that requires you to continue taking your current medication, your doctor can request a coverage review by visiting the Express Scripts online portal at PA.
Express Scripts manages your prescription plan for your employer, plan sponsor, health plan or benefit fund. These excluded medications do not apply to Medicare plans.
Drug Class
ANTIINFECTIVES Antibiotic Agents (Oral) Antibiotic Agents for Urinary Tract Infections Antifungal Agents (Oral) Antivirals (Oral) Chagas Disease Agents AUTONOMIC & CENTRAL NERVOUS SYSTEM Alpha-2 Adrenergic Agonists (for Opioid Withdrawal) Alzheimer's Agents Amyotrophic Lateral Sclerosis (ALS) Agents
Anticonvulsants
Antimigraine Agents
Antiparkinsonism Agents
Antipsychotics (Injectable) Antipsychotics (Oral) Antispasmodic Agents Anxiolytic Agents Cataplexy Treatment
Excluded Medications
Preferred Alternatives
FIRVANQ, VANCOMYCIN 25 MG/ML SOLUTION SIVEXTRO NITROFURANTOIN 50 MG/5 ML SUSPENSION TOLSURA
SITAVIG, XERESE
LAMPIT
vancomycin capsules, vancomycin 50 mg/ml oral solution linezolid nitrofurantoin 25 mg/5 ml suspension itraconazole acyclovir oral or cream, famciclovir, penciclovir cream, valacyclovir BENZNIDAZOLE
LUCEMYRA
clonidine
ADUHELM, LEQEMBI QALSODY, RELYVRIO EPRONTIA FINTEPLA MOTPOLY XR PRIMIDONE 125 MG TABLETS ZONISADE ONZETRA XSAIL, ZOLMITRIPTAN NASAL SPRAY 2.5 MG VYEPTI ZAVZPRET
APOKYN
DHIVY
GOCOVRI ER, OSMOLEX ER
ONGENTYS XADAGO, ZELAPAR
INVEGA HAFYERA, RYKINDO ER, UZEDY ER
LYBALVI
QUETIAPINE 150 MG TABLETS BACLOFEN SOLUTION, LYVISPAH, OZOBAX, OZOBAX DS LOREEV XR SODIUM OXYBATE (by Amneal), XYREM
No alternatives recommended No alternatives recommended topiramate sprinkle capsules DIACOMIT, EPIDIOLEX lacosamide primidone 50 mg or 250 mg tablets zonisamide sumatriptan nasal spray, ZOMIG NASAL 2.5 MG AIMOVIG, AJOVY, EMGALITY NURTEC ODT, UBRELVY Coverage may be approved for the treatment of Parkinson's Disease under certain conditions. carbidopa/levodopa amantadine capsules, amantadine oral solution, amantadine tablets entacapone rasagiline, selegiline ABILIFY ASIMTUFII, ABILIFY MAINTENA, ARISTADA, RISPERDAL CONSTA aripiprazole, asenapine, lurasidone, olanzapine, paliperidone er, quetiapine, quetiapine er, ziprasidone quetiapine 50 mg or 100 mg, quetiapine er baclofen suspension, baclofen tablets lorazepam tablets LUMRYZ ER, SODIUM OXYBATE (by Hikma), XYWAV
? 2023 Express Scripts. All Rights Reserved. All trademarks are the property of their respective owners.
Page 1
(continued)
CRP2412_16637C 334293 EXCL-NPF-OE-24 (12/20/2023)
Drug Class
Excluded Medications
AUTONOMIC & CENTRAL NERVOUS SYSTEM (continued) Central Nervous System Stimulants
DYANAVEL XR, XELSTRYM
METHYLPHENIDATE ER 45 MG, 63 MG & 72 MG, QUILLICHEW ER, QUILLIVANT XR, RELEXXII ER
Duchenne Muscular Dystrophy (DMD) Agents
AMONDYS 45, EXONDYS 51, VILTEPSO, VYONDYS 53 EMFLAZA
Friedreich's Ataxia Agents
SKYCLARYS
Multiple Sclerosis Agents
BRIUMVI EXTAVIA GILENYA, TASCENSO ODT
APADAZ, BENZHYDROCODONE/ACETAMINOPHEN
CONZIP, QDOLO, TRAMADOL 100 MG TABLETS, TRAMADOL ER CAPSULES, TRAMADOL SOLUTION
NUCYNTA
Narcotic Analgesics & Combinations
NUCYNTA ER, OXYCODONE ER, XTAMPZA ER
OXAYDO, ROXYBOND
PRIMLEV, PROLATE SOLUTION
SEGLENTIS
Narcotic Antagonists
ZIMHI
Rett Syndrome Agents
DAYBUE
Sedative-Hypnotic Agents
DORAL, QUAZEPAM ZOLPIDEM 7.5 MG CAPSULES, ZOLPIMIST
Selective Serotonin Reuptake Inhibitors (SSRIs) Antidepressants
CITALOPRAM CAPSULES, PEXEVA, SERTRALINE CAPSULES
Serotonin/Norepinephrine Reuptake Inhibitor Antidepressants DRIZALMA SPRINKLE, VENLAFAXINE BESYLATE ER
Transmucosal Fentanyl Analgesics
FENTANYL CITRATE BUCCAL TABLETS, FENTORA, SUBSYS
APLENZIN, BUPROPION XL 450 MG, FORFIVO XL
Miscellaneous Antidepressants
AUVELITY ER
SPRAVATO
CARDIOVASCULAR ACE Inhibitors
Alpha-Adrenergic Agonists
QBRELIS CLONIDINE ER 0.17 MG, NEXICLON XR
EDARBI
Angiotensin Receptor Blockers (ARBs) and Combinations
EDARBYCLOR
Anticoagulants
VALSARTAN SOLUTION PRADAXA, SAVAYSA
Preferred Alternatives
dextroamphetamine er, dextroamphetamine/amphetamine er, lisdexamfetamine
dexmethylphenidate er, methylphenidate cd, methylphenidate er, methylphenidate la
No alternatives recommended
prednisone solution, prednisone tablets
Coverage may be approved for the treatment of Friedreich's Ataxia under certain conditions. KESIMPTA, OCREVUS AVONEX, BETASERON, PLEGRIDY, REBIF fingolimod, teriflunomide, BAFIERTAM, MAYZENT, PONVORY, VUMERITY hydrocodone/acetaminophen
tramadol tablets, tramadol er tablets
hydrocodone/acetaminophen, morphine sulfate, oxycodone, tramadol, tramadol/acetaminophen
hydrocodone bitartrate er, hydromorphone er, morphine sulfate er, oxymorphone hcl er, HYSINGLA ER, OXYCONTIN oxycodone
oxycodone/acetaminophen
tramadol tablets plus celecoxib
naloxone syringes
No alternatives recommended
estazolam, lorazepam
eszopiclone, zaleplon, zolpidem tablets
citalopram tablets, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline tablets desvenlafaxine er, duloxetine, venlafaxine hcl er, FETZIMA
fentanyl citrate lozenges
bupropion xl 150 mg or 300 mg bupropion, citalopram, duloxetine, paroxetine, sertraline, venlafaxine, FETZIMA olanzapine/fluoxetine, bupropion, desvenlafaxine er, duloxetine, escitalopram, mirtazapine, sertraline
lisinopril
clonidine patches, clonidine tablets
candesartan, irbesartan, losartan, olmesartan, telmisartan, valsartan
candesartan/hydrochlorothiazide, irbesartan/hydrochlorothiazide, losartan/hydrochlorothiazide, olmesartan/hydrochlorothiazide, telmisartan/hydrochlorothiazide, valsartan/hydrochlorothiazide, chlorthalidone plus valsartan
valsartan tablets dabigatran, ELIQUIS, XARELTO
? 2023 Express Scripts. All Rights Reserved. All trademarks are the property of their respective owners.
Page 2
(continued)
CRP2412_16637C 334293 EXCL-NPF-OE-24 (12/20/2023)
Drug Class
CARDIOVASCULAR (continued) Beta Blockers & Combinations Calcium Channel Blockers Diuretics Fenofibrates HMG & Cholesterol Inhibitor Combinations PCSK9 & siRNA Inhibitors Pulmonary Arterial Hypertension (PAH) Agents Sodium Glucose Co-Transporter-1 and 2 Inhibitors
Miscellaneous Cardiovascular Agents
DERMATOLOGICAL Agents for Hyperhidrosis Oral Agents for Acne
Rosacea Agents (Oral) Rosacea Agents (Topical)
Topical Agents for Acne
Topical Agents for Actinic Keratosis Topical Antifungals Topical Corticosteroids
? 2023 Express Scripts. All Rights Reserved. All trademarks are the property of their respective owners.
Excluded Medications
Preferred Alternatives
HEMANGEOL INDERAL XL, INNOPRAN XL KAPSPARGO SPRINKLE CONJUPRI, LEVAMLODIPINE KATERZIA, NORLIQVA FUROSCIX, SOAANZ THALITONE ANTARA, FENOFIBRATE CAPSULES (30 MG, 50 MG, 90 MG, 150 MG), LIPOFEN
ALTOPREV, ATORVALIQ, EZALLOR SPRINKLE
ROSUVASTATIN/EZETIMIBE LEQVIO, PRALUENT
LIQREV, TADLIQ
INPEFA ASPRUZYO SPRINKLE ER
CORLANOR
LOCODO NORPACE CR
propranolol solution propranolol er metoprolol succinate amlodipine, felodipine er, nifedipine er, nisoldipine amlodipine tablets bumetanide, furosemide, torsemide chlorthalidone fenofibrate capsules (43 mg, 67 mg, 130 mg, 134 mg, 200 mg), fenofibrate tablets, fenofibric acid atorvastatin, fluvastatin er, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin tablets ezetimibe plus atorvastatin or rosuvastatin REPATHA sildenafil oral suspension, sildenafil 20 mg tablets, tadalafil 20 mg tablets FARXIGA, JARDIANCE ranolazine er atenolol, bisoprolol, carvedilol, metoprolol succinate, metoprolol tartrate, propranolol colchicine amiodarone, quinidine sulfate, sotalol
DRYSOL, QBREXZA
Over-the-Counter aluminum chloride containing products
ABSORICA LD
isotretinoin capsules
DORYX DR 80 MG, DORYX MPC, DOXYCYCLINE HYCLATE DR 80 MG
doxycycline hyclate, doxycycline monohydrate
MINOCYCLINE BIPHASIC TABLETS, MINOCYCLINE ER CAPSULES, XIMINO
minocycline 24 hour er tablets
DOXYCYCLINE 40 MG CAPSULES, ORACEA
Oral: doxycycline hyclate, doxycycline monohydrate Topical: azelaic acid, ivermectin, metronidazole
NORITATE
metronidazole
ZILXI
azelaic acid, ivermectin, metronidazole, sodium sulfacetamide/sulfur, FINACEA FOAM
CLENIA PLUS, SULFACETAMIDE/SULFUR 8%-4% CLEANSER, SULFACETAMIDE/SULFUR 9%-4.25% SUSPENSION, ZMA CLEAR
sulfacetamide/sulfur 9%-4% cleanser, sulfacetamide/sulfur 8%-4% suspension
FABIOR, TAZAROTENE FOAM
tazarotene cream, tretinoin
VELTIN
clindamycin/benzoyl peroxide, clindamycin/tretinoin, erythromycin/benzoyl peroxide
WINLEVI
azelaic acid, clindamycin phosphate gel, clindamycin/tretinoin, dapsone, erythromycin gel, tretinoin
CARAC, FLUOROURACIL 0.5% CREAM, KLISYRI, ZYCLARA
diclofenac 3% gel, fluorouracil 5% cream, fluorouracil 2% solution, imiquimod 5% cream
ECOZA, ERTACZO, LULICONAZOLE, LUZU, OXISTAT LOTION, SULCONAZOLE, XOLEGEL
ciclopirox, clotrimazole, econazole, ketoconazole, naftifine, oxiconazole
MICONAZOLE/ZINC OXIDE/PETROLATUM, VUSION
clotrimazole, ketoconazole, miconazole, nystatin
CLOCORTOLONE PUMP, HALOBETASOL 0.05% FOAM, IMPOYZ, LEXETTE, SERNIVO, ULTRAVATE, VERDESO FOAM
generic topical corticosteroids
Page 3
(continued)
CRP2412_16637C 334293 EXCL-NPF-OE-24 (12/20/2023)
Drug Class
DERMATOLOGICAL (continued) Vitamin D Analogs (Topical)
Miscellaneous Topical Dermatological Agents
DIABETES Biguanidine Agents Blood Glucose Meters & Test Strips
Diabetic Pen Needles & Syringes
Excluded Medications
CALCIPOTRIENE FOAM, SORILUX
ALCORTIN A
CONDYLOX, VEREGEN
LIDOCAINE/TETRACAINE, PLIAGLIS
TAZORAC 0.05% CREAM
TRI-LUMA
YCANTH
METFORMIN 625 MG TABLETS
ASCENSIA (CONTOUR) ONETOUCH SOLUTIONS STARTER KIT ROCHE (ACCU-CHEK) TEMPO (WELCOME KIT, REFILL KIT, SMART BUTTON) TRIVIDIA (TRUETEST, TRUETRACK) ALL OTHER METERS & TEST STRIPS THAT ARE NOT LISTED AS PREFERRED
PEN NEEDLES & SYRINGES BY: ARKRAY HOME AIDE DIAGNOSTICS HTL-STREFA NOVO NORDISK OWEN MUMFORD PRODIGY DIABETES CARE SIMPLE DIAGNOSTICS TRIVIDIA (NIPRO DIAGNOSTICS) ULTIMED ALL OTHER DIABETIC PEN NEEDLES & SYRINGES THAT ARE NOT LISTED AS PREFERRED
Diabetic Supply Kits
BIGFOOT UNITY PROGRAM KIT
ALOGLIPTIN, NESINA, TRADJENTA
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors & Combinations
ALOGLIPTIN/METFORMIN, JENTADUETO, JENTADUETO XR, KAZANO
ALOGLIPTIN/PIOGLITAZONE
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors/Sodium Glucose Co-Transporter-2 (SGLT-2) Inhibitors Combinations
QTERN, STEGLUJAN
Glucagon-Like Peptide-1 Agonists
VICTOZA
Glucose-Elevating Drugs
GLUCAGEN HYPOKIT, GLUCAGON EMERGENCY KIT (by Fresenius), ZEGALOGUE
Insulin (Basal) and Glucagon-Like Peptide-1 (GLP-1) Agonist Combinations
XULTOPHY
ADMELOG, AFREZZA, APIDRA, FIASP, INSULIN ASPART, NOVOLOG, RELION NOVOLOG
Insulins
INSULIN DEGLUDEC, INSULIN GLARGINE (by Winthrop), INSULIN GLARGINE-YFGN, LANTUS, LEVEMIR, REZVOGLAR
INSULIN ASPART PROTAMINE, NOVOLOG MIX, RELION NOVOLOG MIX
NOVOLIN, NOVOLIN MIX, RELION NOVOLIN, RELION NOVOLIN MIX
Sodium Glucose Co-Transporter-2 (SGLT-2) Inhibitors & Combinations
BRENZAVVY, INVOKANA INVOKAMET, INVOKAMET XR
Preferred Alternatives
calcipotriene, calcitriol generic topical corticosteroids plus mupirocin imiquimod 5% cream, podofilox solution lidocaine cream, lidocaine/prilocaine cream tazarotene 0.1% cream fluocinolone acetonide, hydroquinone, tretinoin No alternatives recommended metformin 500 mg or 850 mg tablets FREESTYLE KITS/METERS (FREESTYLE FREEDOM, FREESTYLE FREEDOM LITE, FREESTYLE INSULINX, FREESTYLE LITE) FREESTYLE TEST STRIPS (FREESTYLE, FREESTYLE INSULINX, FREESTYLE LITE) ONETOUCH KITS/METERS (ULTRA2, VERIO FLEX) ONETOUCH TEST STRIPS (ULTRA, VERIO) PRECISION XTRA METERS, TEST STRIPS
BD DIABETES PEN NEEDLES BD DIABETES SYRINGES
DEXCOM G6: RECEIVER, SENSOR, TRANSMITTER DEXCOM G7: RECEIVER, SENSOR FREESTYLE LIBRE: READER, SENSOR saxagliptin, JANUVIA saxagliptin/metformin, JANUMET, JANUMET XR pioglitazone plus JANUVIA GLYXAMBI BYDUREON BCISE, BYETTA, OZEMPIC, TRULICITY glucagon emergency kit (by Amphastar), BAQSIMI, GVOKE
SOLIQUA HUMALOG, HUMALOG TEMPO, INSULIN LISPRO, LYUMJEV, LYUMJEV TEMPO
SEMGLEE (YFGN), TOUJEO, TRESIBA
HUMALOG MIX, INSULIN LISPRO PROTAMINE MIX
HUMULIN, HUMULIN MIX FARXIGA, JARDIANCE, STEGLATRO SEGLUROMET, SYNJARDY, SYNJARDY XR, XIGDUO XR
? 2023 Express Scripts. All Rights Reserved. All trademarks are the property of their respective owners.
Page 4
(continued)
CRP2412_16637C 334293 EXCL-NPF-OE-24 (12/20/2023)
Drug Class
DIABETES (continued) Sulfonylurea Agents EAR/NOSE Nasal Steroids Otic Antibiotics & Combination Products
ENDOCRINE Cushing's Agents Gonadotropin-Releasing Hormone (GnRH) Analogs (for Central Precocious Puberty) Growth Hormones
Somatostatin Analogs
Testosterone Products
Thyroid Replacement Therapy Miscellaneous Endocrine Agents GASTROINTESTINAL Antidiarrheal Agents
Antiemetics (Oral)
Bowel Evacuants Corticosteroids (Rectal Formulations) Fecal Microbiota Agents Gallstone Dissolution Agents Gastroparesis Agents Helicobacter Pylori Agents
Hemorrhoidal Preparations
Inflammatory Bowel Agents Irritable Bowel Syndrome & Chronic Constipation Agents Pancreatic Enzymes
Excluded Medications
Preferred Alternatives
GLIPIZIDE 2.5 MG TABLETS
glipizide 5 mg tablets
BECONASE AQ, OMNARIS, QNASL, ZETONNA
flunisolide, fluticasone, mometasone
CETRAXAL CIPRO HC, CIPROFLOXACIN/FLUOCINOLONE OTIC ISTURISA KORLYM RECORLEV
ciprofloxacin otic, ofloxacin otic ciprofloxacin/dexamethasone otic SIGNIFOR ketoconazole, LYSODREN, SIGNIFOR ketoconazole, LYSODREN
LUPRON DEPOT-PED, SUPPRELIN LA
FENSOLVI, TRIPTODUR
HUMATROPE, NORDITROPIN FLEXPRO, NUTROPIN AQ NUSPIN, SAIZEN, SAIZENPREP, ZOMACTON
GENOTROPIN, OMNITROPE
SKYTROFA, SOGROYA
GENOTROPIN, OMNITROPE, NGENLA
LANREOTIDE, SANDOSTATIN LAR DEPOT
SOMATULINE DEPOT
SIGNIFOR LAR
For Acromegaly: SOMATULINE DEPOT For Cushing's Disease: SIGNIFOR
AVEED
testosterone cypionate, testosterone enanthate
KYZATREX, NATESTO, TLANDO
testosterone gel, testosterone solution, ANDRODERM PATCHES
ADTHYZA
levothyroxine tablets, ARMOUR THYROID
LEVOTHYROXINE CAPSULES, THYQUIDITY, TIROSINT, TIROSINT-SOL
levothyroxine tablets
CORTROPHIN GEL
No alternatives recommended
MYTESI
diphenoxylate/atropine, loperamide
AKYNZEO CAPSULES ANTIVERT, MECLIZINE 50 MG TABLETS ANZEMET BONJESTA EMEND POWDER PACKETS
CLENPIQ, OSMOPREP, PLENVU, SUFLAVE, SUTAB
CORTIFOAM
REBYOTA
RELTONE GIMOTI
VOQUEZNA
HYDROCORTISONE/PRAMOXINE 25-18 MG SUPPOSITORIES PROCTOFOAM-HC
DIPENTUM
IBSRELA, MOTEGRITY, ZELNORM PERTZYE
granisetron, ondansetron, aprepitant, VARUBI TABLETS meclizine 25 mg tablets granisetron, ondansetron
doxylamine/pyridoxine hcl
aprepitant, VARUBI TABLETS magnesium sulfate/potassium sulfate/sodium sulfate solution, peg 3350/ascorbic acid powder packets hydrocortisone enema, UCERIS FOAM Coverage may be approved for the prevention of recurrent Clostridioides difficile infection under certain conditions.
ursodiol
No alternatives recommended
bismuth/metronidazole/tetracycline, lansoprazole/amoxicillin/clarithromycin, TALICIA hydrocortisone ac suppositories, pramoxine/hydrocortisone cream
pramoxine/hydrocortisone cream
balsalazide disodium, mesalamine dr, mesalamine er, sulfasalazine, PENTASA 250 MG CAPSULES lubiprostone, LINZESS, TRULANCE CREON, PANCREAZE, ZENPEP
? 2023 Express Scripts. All Rights Reserved. All trademarks are the property of their respective owners.
Page 5
(continued)
CRP2412_16637C 334293 EXCL-NPF-OE-24 (12/20/2023)
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