National PBM Drug Monograph
Neither TBZ, nor the metabolites are likely to be a substrate or inhibitor of P-glycoprotein. TBZ metabolites are primarily renally eliminated.3. Peak plasma concentrations of the metabolites are reached within 1 to 1.5 hours post-dosing.3 The half-lives of α-HTBZ and β-HTBZ are 4-8 hours and 2-4 hours, respectively.3 ................
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