Haematology Notes
Haematology Notes
Haematology History
Recent infection: HUS, ITP
Sx of anaemia: SOBOE, fatigue
Jaundice
Sx of CT disease: joint pain / swelling = sickle cell
Leg ulcers = sickle cell, spherocytosis
Abdo / back pain = sickle cell, paroxysmal nocturnal haemoglobinuria
= gallstones / cholecystitis in haemolytic anaemia
Neuro: spinal cord lesions = spherocytosis, haemolytic anaemia, lymphoma
CVA = sickle cell
Fluctuating = TTP
DH: drugs cause haemolytic anaemia
Anticoagulation
Thrombotic prophylaxis
PMH: operations (eg. mechanical heart valve)
PMH of haemolytic episodes – sickle cell, spherocytosis
Thrombotic tendancy
Unexplained miscarriages = antiphospholipid syndrome
MI = factor V Leiden
FH: thrombotic tendancy
SH: ethnic background
RF for thrombosis (eg. smoking, OCP, pregnancy, malignancy, recent surgery,
immobility)
Haematology Examination
Skin: Bruises (ecchymoses, petechiae) = thrombocytopenia, scurvy
Pigmentation = lymphoma, Fe overload in thalassaemia
Rashes = lymphoma
Ulceration = neutropenia
Cyanosis, plethora = polycythaemia
Jaundice = haemolysis
Scratch marks = myeloproliferative, lymphoma
Palpable purpura = vasculitis, dysglobinaemia, bacteraemia
racial origin
Temp
Hands: koilonychia = Fe def anaemia
Pale palmar creases = anaemia, Hb ................
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