Investigating DVT

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Investigating DVT

An approach to symptoms suggestive of lower limb deep vein thrombosis (DVT)

Clinical suspicion of DVT

Common symptoms: Swelling Redness Pain

Typically throbbing in nature, and comes on while walking or bearing weight

Patients may also be asymptomatic, having had investigation for other conditions such as pulmonary embolism or malignancy

Critical features or limb

threatened

Venous clot

Swelling and inflammation below

site of blockage

Active cancer treatment

(ongoing, within 6

+1

months, or palliative)

Localised tenderness along

distribution of deep venous +1

system

Pitting oedema (greater

in symptomatic leg)

+1

Modi ed Wells score (2003)

Paralysis, paresis, recent

immobilisation of the

+1

lower limbs

Entire leg swelling

+1

Collateral superficial

veins (non-varicose)

+1

Recently bedridden for

more than 3 days, or major +1

surgery within 4 weeks

Calf swelling >3cm

compared with

+1

asymptomatic leg

Previous documented

DVT

+1

Total score: ?2 ?1 0 1 2 3 4 5 6 7 8 9

DVT unlikely

DVT likely

Alternative diagnosis as likely, or more likely than DVT

?2

The D-dimer blood test has high sensitivity but is not very specific. D-dimer can be raised in other conditions, including:

Malignancy Infection

Pregnancy Post surgery

Inflammation/trauma

High/moderate sensitive D-dimer test

Negative

Positive

If D-dimer not available or inappropriate

Either proximal or whole leg ultrasound is recommended in high risk cases

Lower limb ultrasound

Negative

Positive

Lower limb ultrasound

Negative

Positive

Proximal, above knee ultrasound is recommended in low risk cases

Discuss with specialist

Consider interim ultrasound or alternate imaging

DVT excluded

If diagnostic testing will take longer than 4 hours, begin interim anticoagulation treatment

Treat as DVT

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