Thyroid Function Ordering Algorithm*
[Pages:1]Thyroid Function Ordering Algorithm*
Nonhospitalized patients without known or suspected pituitary disease
Begin evaluation by ordering either the cascade approach THSCM / Thyroid Function Cascade, Serum
(all appropriate tests are performed automatically) or each test individually, beginning with STSH / Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum
Thyroid stimulating hormone (TSH)
4.2 mIU/L*
Hyperthyroid suspected
Test: FRT4 / T4 (Thyroxine), Free, Serum
If Free T4 is normal
Test: T3 / T3 (Triiodothyronine), Total, Serum
Borderline low TSH
Test: FRT4 / T4 (Thyroxine), Free, Serum
No further testing unless clinically indicated
Hypothyroid suspected
Test: FRT4 / T4 (Thyroxine), Free, Serum TPO / Thyroperoxidase
Antibodies, Serum
* For 12 hours before specimen collection for any thyroid test listed in this algorithm, the patient should not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
** Adult s-TSH reference ranges. For pediatric intervals, see STSH / Thyroid-Stimulating Hormone-Sensitive (s-TSH), Serum
? Mayo Foundation for Medical Education and Research (MFMER). All rights reserved.
10/2021
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