Table S1. List of ICD-10 codes for bleeding Number …

[Pages:3]Table S1. List of ICD-10 codes for bleeding

ICD-10 code

ICD label

Total bleeding

IH

D62

Acute posthaemorrhagic anaemia

D683 Haemorrhagic disorder due to circulating anticoagulants

D698 Other specified haemorrhagic conditions

D699 Haemorrhagic condition, unspecified

H113 Conjunctival haemorrhage

H210 Hyphaema

H313 Choroidal haemorrhage and rupture

H356 Retinal haemorrhage

H431 Vitreous haemorrhage

H450 Vitreous haemorrhage in diseases classified elsewhere

H922 Otorrhagia

I230

Haemopericardium as current complication following acute myocardial infarction

I312

Haemopericardium, not elsewhere classified

I600

Subarachnoid haemorrhage from carotid siphon and bifurcation

I601

Subarachnoid haemorrhage from middle cerebral artery

I602

Subarachnoid haemorrhage from anterior communicating artery

I603

Subarachnoid haemorrhage from posterior communicating artery

I604

Subarachnoid haemorrhage from basilar artery

I605

Subarachnoid haemorrhage from vertebral artery

I606

Subarachnoid haemorrhage from other intracranial arteries

I607

Subarachnoid haemorrhage from intracranial artery, unspecified

I608

Other subarachnoid haemorrhage

I609

Subarachnoid haemorrhage, unspecified

I610

Intracerebral haemorrhage in hemisphere, subcortical

I611

Intracerebral haemorrhage in hemisphere, cortical

I612

Intracerebral haemorrhage in hemisphere, unspecified

I613

Intracerebral haemorrhage in brain stem

I614

Intracerebral haemorrhage in cerebellum

I615

Intracerebral haemorrhage, intraventricular

I616

Intracerebral haemorrhage, multiple localized

I618

Other intracerebral haemorrhage

I619

Intracerebral haemorrhage, unspecified

I620

Subdural haemorrhage (acute)(nontraumatic)

I621

Nontraumatic extradural haemorrhage

I629

Intracranial haemorrhage (nontraumatic), unspecified

I850

Oesophageal varices with bleeding

I983

Oesophageal varices with bleeding in diseases classified elsewhere

J942

Haemothorax

K226 Gastro-oesophageal laceration-haemorrhage syndrome

K250 Gastric ulcer: Acute with haemorrhage

K252 Gastric ulcer: Acute with both haemorrhage and perforation

K254 Gastric ulcer: Chronic or unspecified with haemorrhage

K256 Gastric ulcer: Chronic or unspecified with both haemorrhage and perforation

K260 Duodenal ulcer: Acute with haemorrhage

K262 Duodenal ulcer: Acute with both haemorrhage and perforation

K264 Duodenal ulcer: Chronic or unspecified with haemorrhage

K266 Duodenal ulcer: Chronic or unspecified with both haemorrhage and perforation

K270 Peptic ulcer, site unspecified: Acute with haemorrhage

K272 Peptic ulcer, site unspecified: Acute with both haemorrhage and perforation

K274 Peptic ulcer, site unspecified: Chronic or unspecified with haemorrhage

K276 Peptic ulcer, site unspecified: Chronic or unspecified with both haemorrhage and perforation

K280 Gastrojejunal ulcer: Acute with haemorrhage

K282 Gastrojejunal ulcer: Acute with both haemorrhage and perforation

K284 Gastrojejunal ulcer: Chronic or unspecified with haemorrhage

K286 Gastrojejunal ulcer: Chronic or unspecified with both haemorrhage and perforation

K290 Acute haemorrhagic gastritis

K625 Haemorrhage of anus and rectum

K661 Haemoperitoneum

K762 Central haemorrhagic necrosis of liver

K920 Haematemesis

K921 Melaena

K922 Gastrointestinal haemorrhage, unspecified

M250 Haemarthrosis

N020 Recurrent and persistent haematuria: Minor glomerular abnormality

N021 Recurrent and persistent haematuria: Focal and segmental glomerular lesions

N022 Recurrent and persistent haematuria: Diffuse membranous glomerulonephritis

N023 Recurrent and persistent haematuria: Diffuse mesangial proliferative glomerulonephritis

N024 Recurrent and persistent haematuria: Diffuse endocapillary proliferative glomerulonephritis

N025 Recurrent and persistent haematuria: Diffuse mesangiocapillary glomerulonephritis

N026 Recurrent and persistent haematuria: Dense deposit disease

N027 Recurrent and persistent haematuria: Diffuse crescentic glomerulonephritis

N028 Recurrent and persistent haematuria: Other

N029 Recurrent and persistent haematuria: Unspecified

N421 Congestion and haemorrhage of prostate

N920 Excessive and frequent menstruation with regular cycle

N921 Excessive and frequent menstruation with irregular cycle

N923 Ovulation bleeding

N924 Excessive bleeding in the premenopausal period

N930 Postcoital and contact bleeding

N938 Other specified abnormal uterine and vaginal bleeding

N939 Abnormal uterine and vaginal bleeding, unspecified

N950 Postmenopausal bleeding

R040 Epistaxis

R041 Haemorrhage from throat

R042 Haemoptysis

R048 Haemorrhage from other sites in respiratory passages

R049 Haemorrhage from respiratory passages, unspecified

R31

Unspecified haematuria

R58

Haemorrhage, not elsewhere classified

S064 Epidural haemorrhage

S065 Traumatic subdural haemorrhage

S066 Traumatic subarachnoid haemorrhage

S260 Injury of heart with haemopericardium

S271 Traumatic haemothorax

T792 Traumatic secondary and recurrent haemorrhage

Open circle represents including criteria (Total bleeding, IH, or GH).

ICD-10: International Classification of Diseases 10th revision, IH: intracranial hemorrhage, GH: gastrointestinal hemorrhage

GH

Number of Number of claims patients

3,866

1,325

137

23

379

121

56,635 21,170

61,186 39,197

2,700

1,096

101

19

31,018

7,732

30,120

3,893

0

0

571

401

19

1

33

5

1,248

191

750

135

1,034

181

79

16

163

35

387

74

287

48

20

8

835

174

39,159 12,995

16,103

1,711

347

103

0

0

2,766

272

3,544

1,287

2,055

385

23

7

1

1

77,154 39,402

7,530

2,236

27

8

719

532

2,302

280

0

0

2,634

1,295

3,147

1,066

20,777

7,508

18

10

39,267

8,809

45

16

1,246

350

37

14

3,972

902

58

9

2,026

732

0

0

0

0

0

0

0

0

0

0

134

32

0

0

8,464

3,016

8,510

3,765

3,986

2,153

0

0

2,214

1,055

95,180 39,396

57,865 25,180

2,043

705

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

434

117

0

0

0

0

422

281

661

269

24

19

117

41

60,685 25,128

340

157

79,045 36,062

1,672

950

14,669

4,149

3,155

714

681

137

209,959 66,300

0

0

2,994

996

8,285

2,785

5,326

1,904

0

0

617

298

0

0

Case 1

Registered in

database

AF diagnosis

Index date (OAC prescription)

Dosing period

Bleeding event

Figure S1

12-months pre-index period

Follow-up period

Case 2

Registered in

database

AF diagnosis

Index date (OAC prescription)

Dosing period

Censoring

Discontinuation or

switch to next OAC drug

12-months pre-index period

Follow-up period

Case 3

Registered in

database

AF diagnosis

Index date (OAC prescription)

Dosing period

12-months pre-index period

Follow-up period

End of follow-up April 2016

Fig. S1 Schematic representation of study design. Case 1: bleeding event, Case 2: censoring, Case 3: end of the study. Index date: Initiation of oral anticoagulant therapy (should be between April 2012 and March 2015) Discontinuation: When the prescription interval exceeded 3 months, it was judged that medication was discontinued. Registered in database: Start of observation AF: atrial fibrillation, OAC: oral anticoagulant

 ................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download