Oral Pigmentation - Yola

Failure of production of cortisol means that there is positive feedback mechanism on the hypothalamus leads to an elevation of adrenocorticotrophic hormone (ACTH).This in turn stimulate the adrenal gland to undergo a form of hyperplasia, and the excessive production of progesterone and its precursor (17α -hydroxyprogesterone) ,which is ... ................
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