PRG/09/03 - Cirad
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Registered charity no.210183. 183 Euston Rd, London, NW1 2BE. Tel: +44 (0)20 7611 8888 Fax: +44 (0)20 7611 8545
ANIMAL HEALTH IN THE DEVELOPING WORLD INITIATIVE
|note to applicants |
|sUBMISSION PROCEDURES HAVE CHANGED. PLEASE CONSULT THE ACCOMPANYING GUIDANCE NOTES FOR INFORMATION |
PLEASE READ THE TRUST'S GRANT CONDITIONS (wellcome.ac.uk/fundingpolicy)
IN CONJUNCTION WITH THIS APPLICATION FORM.
A MACINTOSH COMPATIBLE (.rtf) VERSION IS AVAILABLE BY CONTACTING THE TRUST DIRECTLY.
If you have any general questions or comments about the completion of this form then please contact:
Animal Health in the Developing World
Wellcome Trust
183 Euston Road
London NW1 2BE
UK
Tel: (0)20 7611 8710
Fax: (0)20 7611 7288
E-mail: livestock@wellcome.ac.uk
If you are experiencing technical difficulties with the form please call: (0)20 7611 8206.
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Registered charity no.210183. 183 Euston Rd, London, NW1 2BE. Tel: +44 (0)20 7611 8888 Fax: +44 (0)20 7611 8545 wellcome.ac.uk
APPLICATION FOR BIOMEDICAL RESEARCH SUPPORT UNDER THE
ANIMAL HEALTH IN THE DEVELOPING WORLD INITIATIVE
(Please read the guidance notes in conjunction with this form)
|Q1 Applicants |Principal Applicant |Joint-applicant (1) |Joint-applicant (2) |
|Surname |DE LA ROCQUE |VAN DEN BOSSCHE |ROGERS |
|Forenames |Stephane |Peter |David John |
|Title (Professor, Dr, Mrs etc.) |Dr |Dr |Professor |
|Position |Research Scientist |Research Scientist |Professor of Ecology |
|Institution |CIRAD-EMVT |ITM |Oxford University |
| |Joint-applicant (3) |Coapplicant (4) |Coapplicant (5) |
|Surname |SIDIBE |MUBANGA |Matjila |
|Forenames |Issa |Joseph |Tshepo Paul |
|Title (Professor, Dr, Mrs etc.) |Dr |Dr |Dr |
|Position |Research Scientist |Chief Tsetse Biologist |Lecturer |
|Institution |CIRDES |Ministry of Agriculture |University of Pretoria |
| |Coapplicant (6) |Coapplicant (7) |Coapplicant (8) |
|Surname |BOUYER |THEVENON |KABORE |
|Forenames |Jeremy |Sophie |Idrissa |
|Title (Professor, Dr, Mrs etc.) |Dr |Dr |Mr |
|Position |Junior Research Scientist |Research Scientist |Research Scientist |
|Institution |CIRDES |CIRDES |CIRDES |
| |Coapplicant (9) |Coapplicant (10) |Coapplicant (11) |
|Surname |SIBERT | | |
|Forenames |Alexandre | | |
|Title (Professor, Dr, Mrs etc.) |Dr | | |
|Position |Research Scientist | | |
|Institution |CIRAD | | |
|Q2 |Name and address of the administering institution(s) (include details of all joint applicants’ institutions) |
| |(maximum of four allowed): |
| |
|Cirad-emvt: Centre International de Recherche Agronomique pour le Développement, Campus international de Baillarguet, 34398 Montpellier Cedex 5, France- |
|cirad.fr |
|Prince Leopold Institute of Tropical Medicine, Veterinary Department, Nationalestaat 155, 2000 Antwerpen, Belgique - |
|University of Oxford, TALA Research Group, Department of Zoology, South Parks Rd., Oxford OX1 3PS, United Kingdom. |
|Cirdes: Centre International de Recherche-Devloppement sur l’Elevage en zone Sub-humide, BP454, 01 Bobo Dioulasso, Burkina Faso |
| |
|Q3 |Period for which support is sought (state in months): |36 |
| | | |
|Q4 |Proposed start date (dd/mm/yy): |01-01-2005 |
| | | |
|Q5 |Title of project (no more than 220 characters): | |
| |
|Environmental changes in Africa and tsetse habitat fragmentation: epidemiological consequences and perspectives for control |
|Principal applicant: |Stéphane de La Rocque, Cirad-Emvt |
| | |
|Title of project: |Environmental changes in Africa and tsetse habitat fragmentation: epidemiological consequences and perspectives for control |
| | |
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|Wellcome Trust Data Protection Statement |
|The Wellcome Trust is committed to protecting your personal information. Information that you supply to the Wellcome Trust in connection with this |
|application (which includes all information sent to the Wellcome Trust that relates to your application, or, in the event of an award, relates to that |
|award) will be used to process your application and for the purposes of audit and/or evaluation. It may also be disclosed to external peer reviewers, some |
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Undertakings
1. I confirm that I (and all those providing personal information in the application) have read and understood the Wellcome Trust Data Protection Statement above.
2. To the best of my knowledge, the information provided in this application is accurate and complete.
3. I have read the conditions under which grants are awarded and, if a grant is made, I agree to abide by them.
|Signature of Principal Applicant |S. de La Rocque |Date: | |
|Signature of Head of Department |E. Camus |Date: | |
|Signature of Joint-applicant (1) |P. Van den Bossche |Date: | |
|(delete “Joint” or “Co” as appropriate) | | | |
|Signature of Head of Department |P. Dorny |Date: | |
|Signature of Joint-applicant (2) |D. J. Rogers |Date: | |
|Signature of Head of Department |P. Harvey |Date: | |
|Signature of Joint-applicant (3) |I. Sidibe |Date: | |
|Signature of Head of Department |A. Gouro |Date: | |
|Signature of Coapplicant (4) |J. Mubanga |Date: | |
|Signature of Head of Department |P. Sinyangwe |Date: | |
|Signature of Coapplicant (5) |T.P.Matjila |Date: | |
|Signature of Head of Department |J. A. W. Coetzer |Date: | |
|Signature of Coapplicant (6) |J.Bouyer |Date: | |
|Signature of Head of Department |E. Camus |Date: | |
|Signature of Coapplicant (7) |S. Thevenon |Date: | |
|Signature of Head of Department |E. Camus |Date: | |
|Signature of Coapplicant (8) |I. Kabore |Date: | |
|Signature of Head of Department |A. Gouro |Date: | |
|Signature of Coapplicant (9) |A. Sibert |Date: | |
|Signature of Head of Department |E. Camus |Date: | |
For and on behalf of the Institution(s) of the Principal and Joint Applicants (maximum of 4 Joint Applicants):
|Signature of Secretary of Institution/Finance Officer |G. Lacombe |Date: | |
|Position: |Finance officer |Institution: Cirad-Emvt |
|Signature of Secretary of Institution/Finance Officer |J Van Lint |Date: | |
|Position: |Finance officer |Institution: ITM |
|Signature of Secretary of Institution/Finance Officer |P.M. Espinasse |Date: | |
|Position: |Finance officer |Institution: University of Oxford |
|Signature of Secretary of Institution/Finance Officer |O. Koné |Date: | |
|Position: |Finance officer |Institution: CIRDES |
|Principal Applicant |
|Name: |Stephane de La Rocque |
|Title: |Dr |
|Post held: |Head of the Ecology of Vectorial Diseases Unit |
|Address: |Cirad- emvt, TA30/E, campus international de Baillarguet, 34398 Montpellier, France |
| | |
|Tel: |(33) 4 67 59 37 22 |
|Fax: |(33) 4 67 59 39 18 |
|E-mail: |stephane.delarocque@cirad.fr |
|Joint-applicant (1) |
|Name: |Peter Van Den Bossche |
|Title: |Dr |
|Post held: |Principal Biologist |
|Address: |Prince Leopold Institute of Tropical Medicine, Veterinary Department, Nationalestaat 155 |
| |2000 Antwerpen, Belgique |
| | |
| | |
|Tel: |32-(0)3-2476396 |
|Fax: |32-(0)3-2476268 |
|E-mail: |pvdbossche@itg.be |
|Joint-applicant (2) |
|Name: |David John Rogers |
|Title: |Professor |
|Post held: |Professor of Ecology |
|Address: |University of Oxford, TALA Research Group, Department of Zoology, South Parks Rd., Oxford OX1 3PS, United Kingdom. |
| | |
| | |
|Tel: |186521240 |
|Fax: |1865271240 |
|E-mail: |david.rogers@zoology.oxford.ac.uk |
|Joint-applicant (3) |
|Name: |Issa Sibibe |
|Title: |Dr |
|Post held: |Head of Biological and Integrated Control Unit (URBIO) |
|Address: |CIRDES, BP 454, 01 Bobo Dioulasso, Burkina Faso. |
| | |
|Tel: |(226) 20 97 22 87 |
|Fax: |(226) 20 97 23 20 |
|E-mail: |is.sidibe@fasonet.bf |
|Coapplicant (4) |Coapplicant (5) |
|Name: |Joseph Mubanga |Name: |Tshepo Matjila |
|Title: |Dr |Title: |Dr |
|Post held: |Chief Tsetse Biologist |Post held: |Lecturer |
|Address: |Dep. of Veterinary and Livestock Development, Ministry of |Address: |Departement of Veterinary Tropical Diseases, University of |
| |Agriculture and Co-operatives, Zambia | |Pretoria, P Bag X04, Onderstepoort, South Africa |
| | | | |
| | | | |
|Tel: |260-1-252608 |Tel: |+ 27 12 5298384 |
|Fax: |260-1-253608 |Fax: |+ 27 12 529 8312 |
|E-mail: |mubangajoseph@ |E-mail: |tshepo.matjila@up.ac.za |
|Coapplicant (6) |Coapplicant (7) |
|Name: |Sophie Thevenon |Name: |Idrissa KABORE |
|Title: |Dr |Title: |M. |
|Post held: |Research Scientist |Post held: |Research Scientist |
|Address: |CIRDES, BP 454, Bobo-Dioulasso, 01 Burkina Faso |Address: |CIRDES, BP 454, Bobo-Dioulasso, 01 Burkina Faso |
| | | | |
| | | | |
|Tel: |(226) 20 97 22 87 |Tel: |(226) 20 97 22 87 |
|Fax: |(226) 20 97 23 20 |Fax: |(226) 20 97 23 20 |
|E-mail: |thevenon@fasonet.bf |E-mail: |i.kabore@fasonet.bf |
|Coapplicant (8) |Coapplicant (9) |
|Name: |Jeremy Bouyer |Name: | |
|Title: |Dr |Title: | |
|Post held: |Junior Research Scientist |Post held: | |
|Address: |CIRDES, BP 454, Bobo-Dioulasso, 01 Burkina Faso |Address: | |
| | | | |
| | | | |
|Tel: |(226) 20 97 22 87 |Tel: | |
|Fax: |(226) 20 97 23 20 |Fax: | |
|E-mail: |carabus@fasonet.bf |E-mail: | |
Q6 Summaries of proposed research (no more than 400 words for each).
|(a) |For scientifically qualified assessors: | |
| | | |
|The epidemiology of tsetse-transmitted human or livestock trypanosomiasis is to a large extend determined by tsetse density, infection rate and host |
|preference. All three contributing factors vary between tsetse populations and within a tsetse population may, often due to differences in the well-being of |
|the tsetse population, vary in time and space. A major factor, contributing to tsetse population stress is human encroachment and concomitant fragmentation of|
|tsetse habitat as a result of the introduction and expansion of mixed farming systems. Understanding the impact of habitat fragmentation on the tsetse |
|population may contribute to the development of more effective control strategies. |
|Riparian and savannah tsetse species play the major role in disease transmission. Therefore, the project will identify study areas in West and southern Africa,|
|where each group is predominant. In those study areas, the fragmentation of riparian vegetation and savannah woodland will be quantified and qualified using |
|environmental and remotely sensed data. Study sites with different degrees of fragmentation will be identified and the tsetse and livestock populations will |
|be monitored. Special attention will go to parameters that can be used to develop population dynamics and disease transmission models. The models will be used|
|to determine (i) the well-being, dynamics and vulnerability of tsetse sub-populations in fragmented habitats, and (ii) the infection rate of hosts and vectors|
|and the related disease transmission risk. Furthermore, analyses of genetic diversity and gene flow between tsetse populations in habitat fragments will make |
|it possible to determine the effect of different levels of fragmentation on the tsetse’s dispersal capacity. This may result in the identification of isolated|
|tsetse populations. Using the findings of the field studies various control approaches will be tested and their appropriateness assessed. |
|The outcomes of the study will be translated into practical guidelines that will facilitate the selection of priority areas for control and the most |
|appropriate control method(s). The guidelines will be transferred to the beneficiaries. |
| |
|(b) |For readers who are not scientifically qualified: | |
| | | |
|The encroachment of people and their livestock has significant impact on the environment and land-use in Africa. One of the consequences of this encroachment |
|is the change in the distribution and occurrence of some diseases, mainly those transmitted by arthropods. Insect like tsetse flies are dependant on suitable |
|habitats and the availability of feeding hosts. Changes in the tsetse’s environment are thus likely to result in variable levels of stress in the tsetse |
|populations, changes in the dynamics of the populations and in some situation their local extinction. Indeed, recent studies have proven that in areas subject |
|to human encroachment, tsetse populations become weakened, more and more fragmented and in some cases isolated. Such vulnerable and isolated populations are |
|ideal priority targets for sustainable vector control even vector removal. However, this can only be exploited when such population can be characterised and |
|identified. |
|The aim of the proposed project is to provide a description of changes in the distribution and density of tsetse as a result of human encroachment and its |
|repercussions on the epidemiology and control of the disease. Considering the contrasting ecology of savannah and riverine tsetse species, the study will be |
|conducted in two African countries (Zambia and Burkina Faso) representing savannah and riverine habitat. Furthermore, each of the countries is experiencing |
|significant and well-documented changes in land-use. The impact of human encroachment on natural habitats will be assessed by analysing historical records and|
|recent remote sensing data. The effect of those habitat changes on the tsetse populations will be assessed through seasonal collections of tsetse from habitats|
|with different degrees of fragmentation. The tsetse samples will be analysed for tsetse density, age-structure (from which mortality rates will be estimated),|
|indicators of ecological stress, parasite infection rates and livestock/tsetse interaction. In addition, the tsetse’s dispersal capacities will be modelled |
|based on evaluation of genetic flow and mathematical tools. The outcomes of the study should facilitate the mapping of vulnerable tsetse populations, tsetse |
|population isolation probability and the spatial distribution of epidemiological challenge. Those outcomes will be exploited and incorporated in guidelines |
|for improved trypanosomiasis control. |
|The Trust may wish to put details of recently awarded grants on to its website. If your application |YES |X |NO | |
|is successful, would you be willing for details of the award to be used in this way? | | | | |
| | | | | |
Q7 Previous applications to the Wellcome Trust
This page may be duplicated for each principal, joint and coapplicant.
|Applicant’s name: |Stephane DE LA ROCQUE |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Principal Applicant |
| |
|General Coordinator of EDEN (Emerging Diseases in a Changing European Environment) Integrated Project, EU, 6th PCRDT, Juny 2004-Nov. 2009. Time spend: 50% |
|ACI (action Incitative Ciblée) of the French Ministry of Research: Bluetongue ecology in the ecosystems of Corsica. 80 000 euros. Time spend : 10% |
|Applicant’s name: |Peter VAN DEN BOSSCHE |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Joint-Applicant |
| |
|DGOS (Directorate General of Development Co-operation). The provision of Animal Health Care to African smallholders. € 100000. September 2000 – January |
|2003. |
| |
|FWO (Foundation for Scientific Research). Genetic diversity in Trypanosoma congolense populations. € 20000. January 2002 - January2005. |
| |
|IAEA (International Atomic Energy Agency). Investigation into the effect of trypanocidal drugs on tsetse’s vectorial capacity. € 13000. September 2003 – |
|September 2005. |
| |
|DGOS (Directorate General of Development Co-operation). Development if a decision-support system for a sustainable control of animal diseases in southern |
|Africa. € 100000. January 2003 – January 2005. |
| |
|Applicant’s name: |David J. ROGERS |
| |
|Is this the Applicant’s first application to the Wellcome Trust | | | NO |X |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
|- Wellcome Showcase Award, 2003-2004: Exploring the use of oceanographic analytical techniques for studying disease epidemiology. Total Grant to Oxford |
|University £125,000 over 2 years. 15% time spend |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Joint-Applicant |
| |
|- HATEL, European Union, 2001-2003, Phillip Mellor/Matthew Baylis IAH, UK: Satellite imagery to map and predict the distribution of Bluetongue virus vectors |
|around the Mediterranean basin.Total Grant (subcontract) to Oxford University/DJR £77,777 over 2 years. 10% time spend. |
|- NY01, NIAID, 2002 – 2007:Laura Kramer NYSDoH, USA: Habitat identification of West Nile Virus vectors in the NY State.Total Grant (subcontract) to TALA |
|Research/DJR $~100,000 over 5 years. 5% time spend. |
|- ISU01, NIH, 2002 – 2007, Elliot Krafsur Iowa State University: Relating tsetse genomics and physiology to environmental variables.Total Grant (subcontract)|
|to Oxford University/DJR ~$60,000 over 3 years. 5% time spend. |
|- BBSRC, 2003-2006, IAH: Assessing the risks of new viral disease arrival in the UK. Total grant (subcontract) to Oxford University/DJR c. £160,000 over 3 |
|years. 10% time spend. |
|- DEFRA, 2003-2006: Assessing the risk of West Nile Virus to the UK. c £220,000 over 3 years. 10% time spend |
|Applicant’s name: |Issa SIDIBE |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Joint-Applicant |
| |
|Germany (BMZ-GTZ): Improving the management of trypanocidal resistance in the cotton zone of West Africa: a regional study, € 1.1 Mill. (ILRI, FU-Berlin, |
|CIRDES, ITC, Vet. Serv. of Burkina Faso, Mali, Guinea), 2003-2005.- the proportion of time spent on: 15% |
| |
|EU: Programme concerté de Recherche-Développement sur l'Elevage en Afrique de l'Ouest (PROCORDEL), Projet N° 8 ACP ROC 011 ; convention n° 6157/REG: € 2.8 |
|Mill (for the sub-programme of Low inputs production systems) ; 2000- mars 2005- the proportion of time spent on : 40% |
| |
|International Atomic Energy Agency (IAEA): application et validation de la PCR et de la PCR-ELISA pour l’amélioration du diagnostic des trypanosomoses |
|africaines dans les zones à faciès épidémiologiques différents au sud-ouest du Burkina Faso, € 41000 ; 1999-2005 : the proportion of time spent on : 15% |
|Applicant’s name: |Joseph MUBANGA |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
| |
|Applicant’s name: |Tshepo MATJILA |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
| |
|Applicant’s name: |Jeremy BOUYER |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Co-Applicant |
| |
|- CEVA Santé Animale (France), “Effect of cattle insecticide treatment (deltaméthrine, VECTOCIDND) by pediluve on tsetse flies (Diptera : Glossinidae)”, 10 |
|000 Euros, june 2004 to june 2005, 10% of time |
|Applicant’s name: |Sophie THEVENON |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Co-Applicant |
| |
|- French ministry of foreign affairs: Identification of genetic markers of tolerance / sensitivity to trypanosomosis in cattle. 65.000 euros, from october |
|2004 to october 2997. Time : 50% |
|Applicant’s name: |Idrissa KABORE |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Co-Applicant |
| |
|- IAEA: “Amélioration et harmonisation des procédures de contrôle de qualité dans l’élevage de masse des glossines”. |
|Contribution : 8,000 US$ started on July 2003 for one year renewable. 20% of time |
|Applicant’s name: |Alexandre SIBERT |
| |
|Is this the Applicant’s first application to the Wellcome Trust | |X | NO | |
| |YES | | | |
| |
|If no, please give details of previous approaches over the last 5 years, including publications resulting from Trust support. |
| |
Q8 Details of other current grants held by applicant(s)
State name of awarding body, title of project, amount awarded, start and end dates of support, for all current grants, indicate the proportion of time spent on each project.
|Co-Applicant |
| |
|- ACI (action Incitative Ciblée) of the French Ministry of Research: ecology of Sahelian ponds and epidemiology of associated diseases (Rift Valley Fiever, |
|West Nile fever and Schistosomosis). 120 000 euros. Time spend : 80% |
Q9 Rationale for the Proposed Research (up to 2 pages)
Explain the importance, relevance and impact of this research to livestock keepers in developing countries. Does the proposed research have either global or national-level implications?
Include: (a) evidence of need from livestock keepers and animal health practitioners; (b) evidence of demand from livestock keepers, animal health practitioners, policy-makers and/or donors; (c) the public health priority of the problem to be addressed; (d) the social, economic and environmental impact of the proposed research; (e) equity of impact of the proposed research e.g. poor versus rich households; (f) how the research topic was derived with respect to the priorities of the end-user at either the institutional or farm level.
Tsetse-transmitted trypanosomiasis is a major constraint to livestock production in about 8 million km2 of sub-Saharan Africa. Experts estimate that in tsetse-infested areas the production of meat is reduced by 30% and milk production by as much as 40%. Other socio-economic analyses have quantified that farmers can breed twice the number of oxen and increase their cultivated area by 300% when trypanosomiasis is controlled (1). In addition, the presence of the disease determines where people decide to live, affects their livestock management practices and the intensification of the crop and livestock integration. Hence, tsetse-transmitted trypanosomiasis should not only be considered as a disease impacting directly on human and animal health but is also a problem that profoundly affects African agriculture and livelihood of rural populations. Tsetse and trypanosomiasis control interventions must thus be seen in the broader context of poverty alleviation, food security and rural development.
Therefore, the integration of T&T control programmes into livestock/agricultural development plans, in well-demarcated priority areas, has become a “condition sine qua non” for successful and sustainable agricultural development. Through such integration, the opportunities for the rural poor can be maximised and, at the same time, the eventual negative effects of the agricultural development on the environment minimised. This approach is in harmony with “The Strategic Framework for FAO 2000-2015” that mentions that interventions have to consider the on-going population change and be economically viable, environmentally sustainable and appropriate both socially and culturally. To support this approach, the Programme Against African Trypanosomiasis (PAAT) was created in 1997. The PAAT is a forum, comprising FAO, WHO, IAEA, AU (formerly OAU)/IBAR and other international and national stakeholders. The PAAT seeks to assist the development and implementation of international policies, strategies and guiding principles for integrated multidisciplinary intervention to alleviate the trypanosomiasis problem.
In July 2000, the AU Heads of States launched the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC). The PATTEC has as objective to mobilise the necessary human, financial and material resources to eliminate the tsetse fly from Africa. The donors’ reaction to this ambitious objective was to consider that any "response strategy” requires broad consultation. Among the prerequisites, they insisted on the need i) to reach a consensus about the methods to be used for identifying the priority areas for control and for collecting the necessary data, and ii) to advocate the use of area-specific control strategies taking into account the environmental constraints and the local epidemiological situation. The latter requires a full understanding of the area-specific epidemiological circumstances. One important factor affecting the local epidemiological landscape is human encroachment into tsetse-infested areas and the concomitant agricultural expansion and tsetse habitat fragmentation. In the short term, such human encroachment may lead to increased rates of transmission of trypanosomes of domestic animal and human (as e.g. in Uganda). In the longer term continued expansion may lead to extensive habitat changes with adverse effects on the tsetse population’s well-being and increasing vulnerability to control interventions. Ultimately, the virtual elimination of trypanosomiasis can be achieved (as e.g. in parts of Nigeria).
Q9 Rationale for the Proposed Research (Cont.)
Strategies for the sustainable control of tsetse-transmitted trypanosomiasis have, during the last ten years, been the subject of many debates at national and international fora. Much of the debate centred on the involvement of the beneficiaries and the identification of priority areas for sustainable trypanosomiasis control in support of rural development. A range of parameters have now been described to identify priority areas. They include the ongoing farming practices, the agricultural potential of the area and the impact of trypanosomiasis on livestock and agricultural production. Area-specific feasibility to control the tsetse population in a sustained way is based at the moment on the assessment of the effectiveness of a particular or combination of tsetse control method. However, taking into account the considerable efforts required to control the vector, active tsetse control should preferably concentrate on areas where tsetse is sufficiently vulnerable to attack such as areas subjected to habitat changes. This approach is likely to reduce the control efforts required from the local communities and rapid improvements of the disease situation are expected.
Understanding the process of tsetse habitat fragmentation and its effect on the tsetse population’s well-being is thus of importance. Once established this relationship can be another important parameter to be used in the identification of priority areas for control and will contribute to the formulation of viable control strategies. Hence the objectives of the proposed project are to analyse and determine the relationship between human encroachment, subsequent tsetse habitat alteration, the effect of the latter on the well-being of the tsetse populations and consequently the epidemiology of trypanosomiasis. Ultimately the outcomes of the study will make it possible to identify the particularities of areas where the tsetse populations are the most vulnerable and, hence the easiest to control. In such areas, high local benefits can be obtained through simple interventions. Furthermore, since habitat changes are most pronounced in areas where the pressure for land is relatively high because of mixed farming the direct and indirect benefits of trypanosomiasis control are expected to be significant. The outcomes of the project will thus help the development of appropriate and more sustainable strategies for T&T control.
Q10 Details of research project (up to 15 pages)
Include: (a) a statement of the scientific questions to be addressed; (b) background information on work that has led to the project; (c) experimental design and methods to be used in investigating this problem, providing sufficient detail for the reviewers of your proposal to assess the likelihood of its success; (d) contributions of the applicants and added value of any proposed collaborations; (e) the training/capacity building for developing countries that will be provided by this project; (f) expected outcomes/health benefits/policy implications; (g) involvement of beneficiaries throughout this project; and (h) any other relevant information.
Based on the concept of area-wide integrated pest management, a set of criteria/guidelines for joint international action against tsetse-transmitted trypanosomiasis has been developed. This concept of data driven decision making based on information from national (country-wide) multidisciplinary databases (e.g. PAAT-Information System, (2)) has led to the identification of priority areas for control. In these areas, more focused studies have revealed the diversity of entomological/epidemiological patterns, requiring different and often integrated intervention tools. Eradication of the tsetse flies can be justified as one of these tools but only where local populations are strictly isolated and vulnerable. Such isolated and vulnerable populations are found on islands (e.g. the successful eradication of G. austeni in Zanzibar) or in mosaic or fragmented landscapes with topographic or/and agro-climatic divisions.
The different species of tsetse flies (Glossina spp.) have various types of preferential habitats resulting in the distinction between savannah-type flies, forest-type flies and flies living in riverine vegetation. Within their specific habitats, tsetse populations are not evenly distributed. For a variety of reasons, populations may concentrate in certain parts of the biotope or on the contrary be absent from other parts. Hence, tsetse distribution depends on a set of specific abiotic (local temperature and humidity, i.e. the microclimate) and biotic (vegetation, feeding hosts) parameters, which may vary at the local scale.
Many studies have demonstrated the direct and indirect impacts of changes in land-use and/or densities of wild or domestic animals on the distribution of tsetse. These man-made changes of the environment usually lead to the fragmentation of the tsetse distribution, mainly due to the changing availability of hosts and/or suitable habitat. Hence, in areas with increasing human densities, tsetse populations become increasingly fragmented with varying degrees of contact between sub-populations (fig.1). The consequences of this progressive habitat fragmentation on tsetse distribution and density, tsetse infection rates, the fitness of the tsetse population, the epidemiology of trypanosomiasis and, finally the choice of methods to control tsetse-transmitted trypanosomiasis still need further evaluation.
The aim of this project is to provide a description of man-made changes to the habitat of tsetse flies in two important agro-ecological zones of Africa (riparian vegetation and savannah woodland) and to determine the repercussions of different degrees of change on the tsetse population, the epidemiology of trypanosomiasis and its control.
statement of the scientific questions to be addressed
The distribution of tsetse flies is the consequence of two main driving forces, of which the importance is likely to vary in the different parts of Africa.
i) Climate: This is of particular relevance in Western Africa where a distinct North – South climatic gradient can be observed. The dry climate in the north drives the tsetse into the more suitable gallery forests of the main rivers. Within the tsetse belt of southern Africa, where only savannah tsetse species are present, the role of climate on the distribution of tsetse is less prominent.
ii) Land-use: changes in land use have considerable impact on the distribution and availability of suitable habitat. Moreover, increased human activity will also affect the availability of wild and domestic host and may result in changes in the tsetse’s feeding patterns.
These considerations have resulted into innovative research work aiming at predicting the presence or absence of tsetse flies in the whole of Africa (3). Those predictions were based on statistical procedures and GIS simulations using remotely sensed and ground measured information on the population and the natural environment. Consecutively, additional independent studies have been conducted at the regional and national levels in different parts of Africa (4-7), confirming the potential of this approach. The main conclusions of these studies were i) that scale-dependant indicators have been proven relevant for tsetse distribution prediction and ii) that those indicators may change according to the ecozone.
In high human density areas of West Africa, the increase of agriculture has been correlated with the decrease of savannah species and contrasted evolutions of riverine tsetse species (8, 9). Finally, the driving force affecting tsetse distribution and density in Western Africa is likely to be the availability of suitable vegetation whereas, in cultivated areas of southern Africa, tsetse distribution appears to be host driven (10).
Understanding the ongoing processes and their respective repercussions on the tsetse populations are essential requirements when developing appropriate trypanosomiasis control strategies. For example, changes in tsetse biotope and resulting ecological stress may affect population fitness and density. In some cases this may lead to the localised disappearance or the fragmentation of the tsetse population. Depending on the gaps between fragments some population may become isolated (fig. 2). Those stressed and isolated populations are ideal priority targets for control. Their characteristics are unfortunately not known.
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The fitness indicators of tsetse populations are all the more pertinent and practical when they can be linked to the eco-physiological characteristics of the local tsetse population. Some physiological parameters, such as the tsetse’s size, its weight or the age structure of the population, can probably be used (11, 12) but their relationship with environmental changes still needs to be established.
Population fitness may also have important epidemiological consequences. For example, a reduced lifespan, because of environmental stress, will reduce the number of flies with mature infections and will reduce the time during which infected flies can transmit the infection. Furthermore, a reduction in the survival time of tsetse will favour the transmission of some trypanosome species, such as Trypanosoma vivax, that have a short maturation phase in the tsetse fly (13). The “vivax ratio” may therefore be an additional useful indicator of population stress.
A wide range of techniques has been developed for vector and/or disease control during the last decennia. It includes the exploitation of natural resistance of livestock, the use of drugs, the application of insecticides, chitin synthetic inhibitors or juvenile hormones to cattle, traps, screens or vegetation and the release of sterile male flies. Decisions on what technique or combination of techniques should be used in a particular area require careful consideration of the area-specific epidemiology of tsetse-transmitted trypanosomiasis and characteristics of local tsetse populations. In this respect, the effect of habitat fragmentation may be an important factor determining the suitability of a control interventions or combination of interventions.
background information on work that has led to the project
In the last decade a series of relevant field studies were conducted which contributed to our understanding of the ecology of tsetse flies and prevailing spatial epidemiological patterns.
In West Africa, a study was conducted in Togo during the 1990’s as part of a Belgian funded FAO trypanosomiasis control project (GCP-TOG-013-BEL). It confirmed that the presence of tsetse in that country remained a major obstacle to cattle production and constrained particularly mixed farming development and intensification. As a comparison, data from outside the tsetse belt (Mali, Niger, Nigeria, Sudan & Chad) showed a very strong positive relationship between sedentary cattle densities and agriculture intensity levels (14). Another important observation of the study in Togo was a confirmation of the long-established fact that the density of West African savannah species of tsetse flies declines when land-use increases (15). Riverine tsetse species, on the other hand, appeared to be less susceptible to human encroachment in the humid South (1300 mm annual rainfall), whereas 600 km up country in the dry Northern part of Togo (1000 mm annual rainfall) G. tachinoides densities also dropped with increasing cropping intensity levels. These observation provided evidence of the importance to plan adapted tsetse and trypanosomiasis control activities at a national level by exploiting the impact of current environmental driving forces on tsetse population fitness or well-being. Finally, options for tsetse control (pour-on, insecticide treated targets) were promoted at the village level, combining implementation of private rural veterinarians and community participatory approaches (15).
At a more detailed scale, a study conducted in an agro-pastoral area of western Burkina Faso compared land-use increase and change in the distribution of three fly species over the past 20 years. Spatial analysis confirmed that significant reductions in the density of tsetse were linked to (i) crop production in the valley, (ii) increased human activities and (iii) indirect impact such as habitat destruction. Interestingly, where soil characteristics nearby the river prevent agricultural expansion and thus protecting the flies’ habitat, increase of human and cattle densities favour tsetse presence as a result of increased host availability (16). In addition, surveys determining the tsetse’s infection rates revealed significant differences at the local scale. In areas where agricultural activity was low, tsetse flies do frequently fed on wild reptiles (monitor lizards or crocodiles) and rarely carried pathogenic trypanosomes. In areas with more dense agricultural activity, most flies fed upon cattle and pigs, and pathogenic trypanosomes infection rates of tsetse were high (17). Additional surveys to determine the incidence of trypanosome infections in sentinel cattle kept in areas with varying degrees of land-use confirmed the differences in host-vector-parasite interaction at a very fine scale. Hereby the intensity of vector-host contact appeared to be more important than fly density when assessing the trypanosomiasis risk. Some of the factors influencing this contact in time and space are related to the physical environment (riverine vegetation, structure of the rivers, geomorphologic profile, distribution and abundance of tsetse flies…) and others to human activity (agricultural occupation, breeding systems, pastoral management …). Epidemiological “hot-spots”, i.e. major disease transmission foci, may thus only accurately be revealed through a multidisciplinary approach taking into account all major components of the agro-ecological and socio-economic systems involved (18).
A model using a GIS and spatial analysis tools was proposed to reveal these epidemiological “hot-spots”. The most favourable habitats for each of the tsetse species were identified using high resolution remote sensing data (SPOT XS). In parallel, a census of stockbreeders, breeding practices and grazing areas made it possible to produce a map of the spatial distribution of cattle in the study area (19). The overlay of tsetse and cattle revealed major host-vector interaction sites (i.e. host-vector interface). It was concluded that, of the 120 km river system prospected in this study, 15 percent appear to harbour higher disease transmission risk (18, 20) and were thus priority areas for control.
A pilot trial was conducted in some of these identified epidemiological “hot-spots” during the last two years. The control strategy was based on two principles: (i) tsetse control aimed at local reduction of tsetse populations and (ii) use of simple and cheap tools (e.g. minimal number of insecticide-treated targets and, in the rainy season, pour-on insecticide application on sedentary cattle). This approach is a prerequisite for reducing costs to obtain community involvement and sustainability of the results. Such a targeted vector control approach appeared to be efficient, not for tsetse eradication, but for decreasing tsetse densities below the threshold of significant parasite transmission, with significant impact on adjacent areas.
After the results obtained in the projects described above, activities were extended to drier areas of Burkina Faso using as an example the Mouhoun river basin, formerly known as the Black Volta. This river network is particularly suitable as a study area representing the dry Northern part of the West-African tsetse belt. It extends over 180 km from North to South within a rainfall range of 1300-1400 mm at the Mouhoun sources (Western south), 1000 mm in the Northern part of the river-bend and 1200 mm in the Eastern leg. It includes a great variety of landscapes and valley profiles including large flood areas in the Western ascending leg and highly cultivated areas with protected forest patches in the descending Eastern leg.
A series of entomological and parasitological surveys were conducted (FAO, GCP-RAF-347-BEL, CIRDES-ILRI BMZ, McDermott, personal communication; CIRAD-CIRDES, (21)) to identify epidemiological patterns in the river basin. Along the Mouhoun river, different epidemiological patterns did not appear to be scattered randomly but as a rule the trypanosomiasis problem became progressively less “intense” when moving to smaller tributaries. Preliminary results of studies of the tsetse population conducted on several sites suggest that although actual population fragmentation is rarely observed, significant indicators of environmental population stress do occur (Bouyer, personal communication): (1) In its Northern part, where macro-climatic conditions appear less favorable, large patches of riparian forests remain. This natural habitat is protected from human impact resulting in locally abundant healthy tsetse populations. (2) Highest population stress (younger age structure and reduced size of individuals) was observed in the eastern descending leg of the Mouhoun river where riparian forests are degraded due to soil erosion and intensive land-use. (3) Along the Western ascending leg, the main stream is surrounded by natural dams creating flood areas, vegetation is luxuriant and tsetse populations are abundant with normal age structures. (4) As a contrast, along the Mouhoun tributaries, small populations of flies have been observed in isolated riparian habitat patches separated by several kilometers of cultivated wetlands.
Although poorly qualified and quantified, the mixed livestock/agriculture farming systems of southern Africa also have significant impact on the environment. In the extensive areas of southern Africa that are suitable for cultivation, savannah woodland is gradually becoming patchy and interspersed with fields. The impacts of this vegetation clearing on the prevailing tsetse population are not well understood. However, in a country like Malawi progressive human encroachment and quest for land have ultimately resulted in the disappearance of tsetse from most cultivated areas. Currently, tsetse flies are restricted to protected game areas or forest reserves and disease transmission occurs at the interface between tsetse-infested and tsetse-free areas (22). In Mozambique, on the other hand, tsetse occurs in extensive areas that have been left undisturbed for nearly 20 years during the civil war (23, 24). Tsetse flies occur in high densities and disease challenge is high in resettlement areas. Between those two extremes, human-induced habitat changes are expected to have a varying impact on the tsetse population and disease transmission dynamics in savannah areas. As in West Africa, understanding this relationship may have significant repercussions on the decision to control and the choice of tools to control.
Field studies conducted under the auspices of the EC-funded Regional Tsetse and Trypanosomiasis Control Programme (RTTCP) and the Belgian-funded Animal Disease Control Programme have revealed some effects of human encroachment on especially G. morsitans morsitans, the major vector of human and livestock trypanosomiasis in southern Africa. Of particular importance were the significant changes in the epidemiology of bovine trypanosomiasis with increasing human and livestock encroachment (25). Depending on the degree of encroachment, the transmission cycle changed from a pure sylvatic, into a mixed sylvatic/domestic, into a domestic cycle where tsetse become highly dependent on livestock (mainly cattle) for their survival. Concurrently, because of the clearing of vegetation for cultivation, the tsetse’s habitat becomes more patchy and tsetse density declines probably as a result of reduced population fitness or increased population stress. Those gradual changes in the tsetse’s habitat and the increasing dependence on livestock as a result of increasing human activities have important repercussions for the fly. Indeed, the seasonal distribution of the fly will be determined by the distribution of suitable habitat fragments, the tsetse’s capacity to move between those fragments and the distribution of the host (mainly cattle), which in turn is determined by prevailing herding practices (10).
Hence, as is the case for the West African riparian tsetse species, current knowledge on tsetse distribution, dispersal capacity and tsetse population dynamics in the changing savannah woodland seems insufficient for the careful planning for sustainable localised trypanosomiasis control. Although most of the currently available tsetse and trypanosomiasis control methods have proven their effectiveness at a large-scale (23), a better understanding of the local situation may make it possible to use those tools on a local scale by exploiting epidemiological particularities such as high dependence on livestock and limited dispersal capacity.
experimental design and methods to be used
An important tool that will be used as foundation for data compilation and analyse is Geographical Information Systems (26). The project aims at using remotely sensed satellite data to feed into statistical models and finally drive the biological models. Existing disease transmission models and biological models will be used to investigate the consequences of habitat change on disease epidemiology and the dynamics of the tsetse population (27, 28). Within the GISs statistical procedures, that have proven to be useful both at the community level to reveal suitable tsetse habitats and epidemiological hotspots (18, 29) and at the regional and continental levels to predict the presence and abundance/prevalence of both tsetse flies and trypanosomiasis (3-6), will be applied.
(i) Scientific proposal:
The study will be carried out in two contrasting study areas: The Mouhoun River area of Burkina Faso, with essentially riparian tsetse species (Palpalis group of tsetse), and the Katete District of Eastern Province of Zambia, with one savannah tsetse species (Glossina morsitans morsitans, Morsitans group of tsetse). Both experimental sites have experienced and still are experiencing significant changes in land-use. The study will address the following questions for each area:
Q1: Is it possible to quantify and qualify habitat fragmentation over time from published records, maps and archived satellite data?
Q2: Is it possible to link tsetse population fitness and population growth rates (specifically the mortality rate) with the nature and degree of habitat fragmentation?
Q3: How does habitat fragmentation affect tsetse dispersal capacity and tsetse genetic diversity?
Q4: How does habitat fragmentation affect the relative availability of domestic and wild tsetse hosts, host preference and the tsetse’s infection rate?
Q5: Is it possible to develop satellite data driven biological models of trypanosome transmission (R0) that capture important seasonal changes in the level and type of trypanosome infection in domestic animals in the two study areas?
Q6: What are the local farmers' perceptions of the trypanosomiasis problem, their strategies for dealing with trypanosome infection in their animals, and how effective and justified are these strategies?
Q7: In the light of the answers to Questions 1) to 6) will it be possible to make recommendations to improve the integrated control of trypanosomiasis, by using current methods or combination of methods more effectively (e.g. improved target/trap placements, insecticidal spraying or strategic use of prophylactic drugs)?
(ii) Study design and Methodology:
The selected study sites are well-documented, with retrospective data on tsetse distribution, tsetse density, disease prevalence and cartographic databases.
Workplan 1 (Q1)- The preliminary work will include the collection of relevant (historical) data on climatic parameters (temperature, rainfall, humidity, …), geomorphology, vegetation (phyto-sociological studies, vegetation structure studies), hydrography (inventory of surface water points, regime), land use and land cover, livestock management practices (description of pastures and rangeland, variation of biomass availability) and epidemiological variables of each study area. Available historical and updated data (obtained through tsetse surveys) on the presence/absence of tsetse (or different tsetse species) will be collected and the link between local environmental factors (vegetation, eco-climatic parameters, land cover/use) and the presence or absence of tsetse will be described.
Spatial classification modeling techniques, using multivariate statistics and spatial analysis tools, will then be adopted to map distinct environmental units (clusters). In particular, human encroachment on natural habitats will be assessed and quantified using fractal dimensions (30) and/or wavelet analyses (31). The dynamic process of habitat fragmentation and the type of fragmentation (size and shape of fragments and distance between fragments) will be determined using landscape indices (32). This will require the use of imagery analysis (e.g. old and recent satellite or aerial images). The GIS analysis will allow quantitative and qualitative appreciation of environmental changes and will make it possible to identify particular study sites with varying degrees of fragmentation where the tsetse population will be monitored and compared.
Workplan 2 (Q2)- In the selected study sites (see above), the tsetse population will be monitored during a period of 12 consecutive months. Depending on the tsetse species, tsetse will be sampled using simple or odour-baited traps or flyrounds. The monthly apparent density of tsetse will be calculated for each study site. Monthly samples will be further analyzed for age-structure (from which mortality rates will be estimated (33)). Physiological age-determination of females will be conducted as described by Saunders (34) and Challier (35). Each fly will be assigned to an ovarian age category depending on its ovarian configuration. For male flies the wings will be excised and fixed to a microscope slide with sticky tape for analysis of wing fray (36). A monthly mean wing fray value will be calculated. The size of the individual flies, a parameter indicating well-being, will be estimated by the length of the wing discal cell cutting edge or other morphometric parameters using a specifically developed computerised tool (software: fly picture measurements, (37)). Tsetse population parameters (apparent density, mortality rates, body size and age distribution) that will be used in models of population dynamics and tsetse population viability will be compared between selected study sites (i.e. habitats with different degrees of fragmentation).
Workplan 3 (Q3) - The effect of habitat fragmentation on the tsetse’s dispersal will be assessed by i) modelling the tsetse’s dispersal capacities, ii) evaluating the gene flow between sub-populations, and iii) assessing the intensity of the genetic drift depending on isolation and population size to forecast extinction probability. This information should allow the determination of the structure of tsetse metapopulations and will make it possible to map environmentally-induced population isolation probability.
The dispersal capacities of the flies will be modelled using sets of historical data on tsetse movement (as such avoiding the use of mark/release/recapture exercises), using mathematical tools including the Meta X software. For riparian flies, models are currently developed by some of the partners. Genetic tools (see below) and quantification of gene flow will strengthen the analyses.
Local tsetse populations will be assessed genetically using micro-satellite markers to reveal genetic diversity and genetic flows. A set of polymorphic microsatellites markers is available for the characterisation of the tsetse species studied in this project. Additional ones could be developed if necessary. Samples of about fifty flies, representative of the different sub-populations, will be selected to reveal genetic structure of the groups and evaluate the diversity within and between populations using F-statistics. The spatial isolation will be studied by auto-correlation methods, test of the mutation-drift equilibrium, effective population size and migration rate.
In addition, selected isolated populations will be chosen depending on their size and other population dynamic parameters such as their reproductive success as determined in Workplan 2. The temporal evolution of genetic diversity with respect to the mutation/drift equilibrium will be monitored in those populations during the duration of the project. Furthermore, current genetic data will be compared with genetic data obtained from old insect collections from the same study sites. These results will be used to assess population trends (decline, statu quo, spread) in fixed environmental settings (i.e. selected study areas) to evaluate i) the “minimum effective population size” and ii) the probability of extinction under environmental evolution hypothesis. Such longitudinal studies were successfully conducted on other insects. Finally, the results will be combined with those from models of population dynamics for population viability obtained from Workplan 2.
Workplan 4 (Q4) - Host availability and host preference in the selected study sites will be determined by identifying the origin of residual blood meals obtained during the dissection of tsetse midguts. The midgut contents will be squashed onto a filter paper disc (Whatman N°1) and each squash labelled. The filter papers will be dried in the air and kept in the dark in a plastic bag together with a desiccant. Bloodmeals will be identified using an ELISA and/or PCR (38).
Finally, the direct and indirect effects of habitat fragmentation on the tsetse population infection rates (prevalence of infection and trypanosome species prevalence) will be determined by dissecting tsetse captured in each of the study sites. Live flies will be dissected within 4 hours of collection. Mouthparts, salivary glands and midgut dissections will be performed using the method described by (39). Presumption of trypanosome species will be made based on the site of infestation (i.e. infections in the proboscis alone will be recorded as vivax-type) but PCR analysis will be used when doubtful (i.e. infection in the midgut and specific diagnosis between T. congolense, T. grayi-like…). Infection rates in tsetse flies will be compared between study sites.
Tsetse-cattle interaction in the selected study sites will be investigated by comparing the tsetse distribution and density patterns with the distribution patterns of cattle. Cattle censuses, using standard questionnaires, will be conducted in the study sites from which information on the tsetse population is being collected (see workplan 1, 2 and 3). Geo-referenced information on the number of cattle and herd composition (age, sex) will be collected. At the same time, information on the number of other livestock species (mainly pigs and goats) will be recorded. Area-specific cattle densities will be calculated and the relationship between habitat fragmentation and cattle density will be determined. Hereby account will be taken of the herd management system and herd movement (20).
Village herds (sentinel herds of about 20 animals) from selected study sites will, during 12 consecutive months, be sampled monthly to determine the incidence of trypanosome infections in cattle (trypanosome species prevalence; haematocrit microscopic examination of blood, Buffy coat technique and PCR detection).
Workplan 5 (Q5) - Given satisfactory outcomes to Q1 to Q5 it will be possible to construct spatially rich biological models of both tsetse and trypanosome prevalence, and possibly even an R0 map for each region (the basic reproduction rate R0 is defined as the number of new infections that arise from a single infection). The value of doing this depends upon the heterogeneity (probably scaling with absolute size) of the areas sampled (Q5).
Workplan 6 (Q6): In the study sites, a survey will be conducted to determine the livestock owners’ perception of the trypanosomiasis problem and their current trypanosomiasis management strategies (e.g. current tsetse control measures and trypanocidal drug use, frequency of treatment, timing of treatment, type of drug used,…). Use will be made of a pre-tested uniform questionnaire (40). The appropriateness of the disease management strategies will be tested using the models developed under workplan 5.
Workplan 7 (Q7) – Finally, a variety of tsetse and trypanosomiasis control options will be i) applied in silico to the transmission models for each study area: the models aim at determining the optimal strategy and timing of interventions; and ii) guidelines for improved control of savannah and riparian species of tsetse and tsetse-transmitted trypanosomiasis in fragmented habitats will be developed and transferred. Current trypanosomiasis disease management practices and perceptions of the trypanosomiasis problem (workplan 6) will be taken into account in these guidelines.
contributions of the applicants and added value of any proposed collaborations
This project is linking two European Research Institutes, two private companies and three African Research Institutes or Departments of Veterinary Services. All the partners have been chosen because of their complementary skills, their experience and expertise in tsetse and trypanosomiasis research and their capacity to transfer practical outcomes to the level of the livestock keeper. Most of them are included in the PAAT Advisory Group (Programme Against African Trypanosomiasis, ) and are regularly consulted by decision makers to assist the development of national and regional trypanosomiasis control strategies. In each institute, the project will be managed by a senior scientist.
The contributing African institutes participate at a national and regional level to the definition of veterinary policies. Work will be conducted by the animal production and health research institution in charge of national tsetse and trypanosomiasis research and control, which have permanent staff in the field. Insofar as possible, it will associate local competence in habitat ecology, environmental sciences and socio-economical sciences.
Some of the institutes linked to the project have a long tradition in collaborating together. The new collaborations in this project will make that the proposed study represents the various African ecotypes and that its outcomes can be transferred to other African countries. In addition, through this collaboration, useful technical tools and scientific methods will be used for the first time by the African partners. To make transfer of those tools easier, working groups on specific topics will be formed (see below).
The acquisition of the information necessary for the study may require resources in terms of people, skills and money which could go well beyond those to be allocated to the project. It is for this reason that the partners have selected complementary and highly representative study areas. The criteria for the selection of the study areas were the following: i) the study areas had to be populated and animal trypanosomiasis had to be a real problem for agricultural development, ii) the study area should have experienced significant changes in land-use and consequently in tsetse distribution and density, with a general trend towards the reduction of favourable habitat and isolation of remaining sub-populations, iii) the study areas should have been subjected to a prior (or current) scientific study, and iv) retrospective data on tsetse distribution and their ecology, epidemiology of the disease and on the environment (cartographic databases on topology, vegetation, land-use, etc) should be available. All the partners are aware that the proposed project supposes the availability of previous data for retrospective and comparable studies and they will place them at the disposal of the project. Finally, the study areas represent the habitat of the principal tsetse groups (riparian flies, savannah flies). The project will thus deal with tsetse species of different ecology and behaviour. This will give the project a range of adapted indicators, tools and methods, some of them being continental and other more specific.
The project draws its inspiration from ecology and bio-geography sciences. Most of the scientific and technical concepts and methods, which will be used in the project and will be applied for the first time to tsetse flies, have been developed during studies conducted on various other species of flora and fauna. The multidisciplinary approach, combining teams of specialists, will give the opportunity to join complementary disciplines and will have considerable added value
Finally, the success of a multi-partner and multidisciplinary project requires active coordination and adequate management to ensure efficient communication and collaboration between all the partners at national and project level. To avoid a major dysfunction, a scientific steering committee will be created and will include a representative of each participating institutions. The steering committee will be created during the “kick-off” meeting at the beginning of the project. It will be chaired by the principal applicant and is responsible for monitoring and evaluating the project’s progress, organising regular workshop and symposia and planning a specific training agenda.
training/capacity building for developing countries
Capacity building will constitute an integral and important part of the project in all its phases. Although it will not be possible to train local scientists fully in all aspects of the research, the project does aim to establish sufficient capacity to sample tsetse populations, to measure important tsetse population parameters, to compare and interpret tsetse population parameters and make prediction with regards to the dynamics of the tsetse population and the transmission of the disease. This will be achieved though on-the-job-training, exchange visits and more specialised training in research institutes. Moreover, to facilitate capacity building, working groups on specific topics (i.e. tsetse ecology and population dynamics, trypanosomiasis epidemiology, molecular genetics and dispersal modelling) will be established in which the local scientists will participate and be exposed to the ongoing innovative scientific research in the fields relevant to the project.
Appropriate on-the-job training courses on topics related to the execution of the project (e.g. entomology, parasitology, epidemiology, genetics, data management and GIS) will be organised in each of the study areas. At the beginning of the project (months 1-4), a forum will be organised to identify these needs (training needs assessment). Course tutors will be scientists at the leading edge of research in tsetse ecology, remote sensing and trypanosomiasis epidemiology. Local experts will be involved in all training courses and used for on-the-job training. To maximise efficiency, the training courses will be conducted within the countries of the African partners making use of their own datasets.
Capacity building in the field of molecular diagnosis of trypanosome infections in tsetse and livestock will be conducted at facilities (e.g. diagnostic laboratories, universities) where the necessary equipment and expertise is available. It is envisaged that at the end of the project the scientists from the African partner country involved in this project are fully conversant with the molecular diagnosis of trypanosomiasis.
Recent developments in the field of molecular biology make it possible to obtain valuable additional information on the tsetse population that will improve our understanding of the dynamics of such populations. Of particular relevance to this project are molecular methods developed to analyse the genetic diversity between tsetse populations, to detect trypanosome infections in livestock and improved molecular methods to identify tsetse hosts. It is beyond the scope of the project to transfer those sophisticated techniques to the respective African countries involved in the project. This would be too expensive and unnecessary considering the restricted field of application. On the contrary, existing facilities and equipment in Africa (e.g. CIRDES, Burkina Faso and DVTD, South Africa) and Europe (e.g. CIRAD, France and ITM, Belgium) will be used. Scientists attached to the project will, however, be exposed to those techniques through exchange visits and discussions with the experts working in those facilities. During those visits emphasis will go to training and capacity building in data analyses and interpretation of molecular results.
Geographical Information Systems (GIS) and techniques for the spatial analysis of disease data are fast moving fields. The use of GIS in assessing vegetation changes have advanced substantially but their application in the field of vector ecology/control is novel. It is envisaged that the scientist will be trained in the use of GIS, in general, and the use of GIS in assessing vegetation changes, in particular. This will be achieved through their active involvement in the first phase of the project when the study of habitat changes will be conducted and ground truthing will be done.
Furthermore, local scientists will be encouraged to improve their knowledge through additional training on specific topics, including complementary remote training (via internet) on specific topics. Such remote training modules are currently developed by some of the European institutes involved.
In addition, participation in international workshops, conferences or seminars will be supported. All teams will also be encouraged to publish relevant scientific results in peer reviewed journals.
At the completion of the project (between months 33-36), a symposium to present and discuss the scientific results of the project will be organised with all the partners. Representatives of other international institutes and decision-maker will be invited and introduced to the findings of the project and the ensuing recommendations for control of trypanosomiasis.
expected outcomes/health benefits/policy implications
Data driven decision making has benefited much from the development of information systems. In addition to the establishment of country wide multidisciplinary data bases, results obtained in West (16, 41), East (42) and southern Africa (7, 43) during the 1990’s have greatly contributed towards the development of area-wide integrated pest management approaches for the control of tsetse and trypanosomiasis. The same studies have indicated the high degree of variation in local epidemiological circumstances and the importance in recognising this variation when designing appropriate localised trypanosomiasis control programmes. It is accepted that most of this variation is a result of human interference with the tsetse’s environment and its direct and indirect impact on the epidemiology of the disease. Nevertheless, the proposed project is the first scientific study of the effects of habitat fragmentation on tsetse populations, trypanosomiasis transmission and its implications for sustainable trypanosomiasis control. The mechanisms of how human interference affects the epidemiology of tsetse-transmitted trypanosomiasis are not well-understood. Through the outcome of this project some of the mechanisms involved will be identified, quantified and transferred into practical guidelines that can be incorporated in decision making for tsetse/trypanosomiasis control. The project will thus contribute to improved and more effective area-specific trypanosomiasis control. This will benefit directly local livestock owners who can obtain a desired level of disease control by more effective use of available control tools and preferably tools that are already applied routinely. Although the project focuses on the control of animal trypanosomiasis, the same principles apply to areas where human sleeping sickness is prevalent. Hence, the outcomes of the project may have important human health benefits in areas where human sleeping sickness is endemic.
The outcomes of the study will contribute to the selection of priority areas for trypanosomiasis control. Tools will become available for the identification of epidemiological “hot spots” or areas of intensive trypanosome transmission in fragmented habitats. Trypanosomiasis control (through the control of tsetse, the control of the disease or a combination of both) could in a first phase focus on those “hot spots” with direct benefits from minimal interventions. In areas where control is dependent on the use of trypanocidal drugs (as is the case in extensive tsetse-infested zones of Africa) trypanocidal drugs will be used more strategically resulting in less costs for the livestock owners but, perhaps more importantly reduced use of trypanocidal drugs. Reduced use of trypanocidal drugs is a major factor retarding the development and spread of trypanocidal drug resistance which is a major impediment to the sustainable control of African trypanosomiasis (44).
Since the project concentrates on the dynamics of habitat change and their repercussions on the epidemiology of trypanosomiasis, predictions can be made on the future of current epidemiological “hot spots” and the appearance of “hot spots” that are at the moment of less epidemiological importance. This is likely to contribute significantly to the appropriate allocation of often limited resources.
When selecting priority area for tsetse control, an important parameter which has to be taken into account is the area-specific feasibility to control the tsetse population in a sustained way. At the moment, the feasibility is based on the assessment of the technical effectiveness of a tsetse control method or combination of methods, usually developed during time-limited projects and tested in extensive areas. However, the scale at which tsetse control operations are conducted is an important factor affecting its effectiveness. Localised control of tsetse has proven to be difficult because of the high invasion pressure of tsetse from surrounding areas and the need to sustain control operations permanently. This is probably one the most important reason why community or beneficiary participation in tsetse control has often failed (45). This has left out tsetse control as an option for control in many areas of Africa. Through the outcomes of the project, however, tools will become available to identify areas within the fragmented habitat where tsetse are isolated or are likely to become isolated in the foreseeable future. Such areas are excellent targets for tsetse control or even tsetse eradication with involvement of local communities and resulting in sustained benefits for livestock owners and other beneficiaries (46). Considering the speed at which resistance to trypanocides is developing in trypanosome populations and the limited range of trypanocidal drugs available, tsetse control will have to remain an option for control. It is believed that the outcomes of the project will make it possible for decision makers or local communities to again consider tsetse control as an effective trypanosomiasis control tool.
Finally, tsetse-transmitted trypanosomiasis will, for the first time, be studied concurrently in Western and southern African agro-ecosystems with common methodologies for all the teams involved. This approach will facilitate exchange and comparison of information between researchers. Furthermore, because of the range of tsetse species involved and the variety of landscapes and landscape dynamics in these different agro-ecosystems, some findings of the project will have continental applications.
involvement of beneficiaries
Considering the scope of the project, beneficiaries are expected at the level of the local community, in particular the livestock owner, who will benefit directly and indirectly from improved animal health and production through more cost-efficient trypanosomiasis control and at the level of national and regional policy makers who will have additional tools in their arsenal of tools to develop strategies for the sustainable control of tsetse-transmitted trypanosomiasis. Involvement in the project of this range of beneficiaries will be achieved in various ways.
Local communities, the main beneficiaries of the project’s outcomes, will be involved throughout the project’s implementation phase. Their input will be essential in order to understand livestock management practices and the dynamics of the mixed livestock farming system. Furthermore, they are the herds of the local communities that will be used in studies on disease transmission. Through this direct involvement, communities will be briefed on the objectives of the project and will receive direct feedback on the outcome of the research.
In the selected study sites, the project partners are known by the local population because of years of field work. Since the project is implemented in partnership with local research institutes and Government departments, their involvement is ensured throughout the project. The scientist attached to the project will brief their respective institutes or departments permanently and, through their training and exposure to new research tools and innovative approaches during the duration of the project, will ensure that parts of the research will continue beyond its existence. Since scientists play a fundamental role in the development of strategies for the control of tsetse-transmitted trypanosomiasis at the national but also the regional level, transfer of knowledge and guidelines to livestock owners but also to other beneficiaries not directly involved in the project is ensured.
At the other extreme of beneficiaries, policy-makers will be regularly informed of the project results. As previously mentioned, most of the experts involved in the project are member of the PAAT-AG (programme Against African Trypanosomosis, Adviser Group, OMS, FAO, IAEA, OUA) or PATTEC and have previously written PAAT strategy guideline. The PAAT and PATTEC channels will be used to inform other beneficiaries on the progress made with the project and thus involve policy makers in the project implementation. Since the objectives of the project are in line with the objectives of the PAAT and PATTEC, they may contribute to the development of generic guidelines for the control of tsetse-transmitted trypanosomosis.
other relevant information : Ethical aspects
This project does not involve human or use of human tissue, use of transgenic animals, use of genetically modified organisms. It involves domestic animals for biological analysis. The project also involves the use of vectors (tsetse flies) for species and biological analysis. All the partners involved in the project have accepted the need to respect the following ethical guidelines in their research practice:
- Observe stringent ethical standards and fully respect and follow national laws and regulations for the treatment of human and animal research participants. Animal samples will be collected during field epidemiological surveys with the co-operation and under the supervision of local animal health authorities. Animal perturbation during samples collection will be lowered to the minimum. Blood sampling will be adapted to the species studied and strictly confined to the best achievement of the project tasks.
- Apply strict standards of honesty and scientific practice in the collection, recording and analysis of data (whether quantitative or qualitative) and other information, and in the dissemination of information, findings and discoveries, including unauthorized duplicate publication;
- Appropriately cite the work of others and use others' writings, discoveries, findings, conceptual developments, unique methods, and data with proper attribution;
- Obtain the permission of others to use their unpublished findings and works, and appropriately acknowledge such sources;
- Obtain the permission of others before using information, concepts or data originally obtained through confidential exchanges, or through access to confidential manuscripts or funding applications that may have been read as a result of activities such as peer review (where permitted by publisher or funding agency regulations).
The research project will not affect the environment but will contribute, through the data collection and analysis, to the monitoring of the evolutions in the environment during the project duration. This monitoring will be of critical relevance for the establishment of efficient animal health related policies and the surveillance of areas at risk.
Q11 References (Research project)
This page may be duplicated to allow applicants to use more than one sheet if necessary (see Guidance Notes).
Please give citations in full, Vancouver style: Your reference list should appear here with the entries listed numerically and in the same order that they have been cited in the text. The format for each reference is as follows: Author, initials. Title. Abbreviated Journal name year; volume: pages. Example of a Vancouver style reference: Russell F D, Coppell A L, Davenport A P. In vitro enzymatic processing of radiolabelled big ET-1 in human kidney as a food ingredient. Biochem Pharmacol 1998;55:697–701.
Swallow B. Impact of trypanosomosis on African agriculture. PAAT position paper, FAO-OMS-IAEA-OAU/IBAR, 1998; 47 p
Gilbert M. The development and use of the Programme Against African Trypanosomiasis Information System (PAATIS). 1999; M. In: ISCTRC Conference, Kenya, 27th September to 1st October 1999, publ. 2001. OUA-STRC: Nairobi, Kenya.
Rogers D. J. & Randolph S. E. Distribution of tsetse and ticks in Africa: past, present and future. Parasitology Today 1993;9:226-271.
Hendrickx G., Napala A., Dao B., Batawui D., De Deken R., Vermeilen A. & Slingenbergh J. H. W. A systematic approach to area-wide tsetse distribution and abundance maps. Bulletin of Entomological Research 1999;89:231-244.
Rogers D. J., Hay S. I. & Packer M. J. Predicting the distribution of tsetse flies in West Africa using temporal Fourier-processed meteorological-satellite data. Annals of Tropical Medicine and Parasitology 1996;90:225-241.
Robinson T., Rogers D. & Brian W. Mapping tsetse habitat suitability in the common fly belt of Southern Africa using multivariate analysis of climate and remotely sensed vegetation data. Medical and Veterinary Entomology 1997;11:235-245.
Robinson T. P. Geographic Information System and the selection of priority areas for control of tsetse-transmitted trypanosomiasis in Africa. Parasitology Today 1998;14:457-461.
Nash T. A. M. Tsetse flies in British West Africa. 1948; L. Colonial Office, United Kingdom.77 pp.&15 Maps.
de La Rocque S., Augusseau X., Guillobez S., Michel V., De Wispelaere G., Bauer B. & Cuisance D. The changing distribution of two riverine tsetse flies over 15 years in an area increasingly occupied by agriculture in Burkina Faso. Bulletin of Entomological Research 2001;91:157-166.
Van den Bossche P. & De Deken R. Seasonal variations in the distribution and abundance of the tsetse fly, Glossina morsitans morsitans in eastern Zambia. Med. Vet. Entomol. 2002;16:170-176.
Buxton P. A. The natural history of tsetse flies. An account of the biology of the genus Glossina (Diptera). 1955; M. N. London School of Hygiene and Tropical Medecine, Lewis H.K. & Co Ltd, London, United kingdom, 816 pp.
Rogers D. J. & Randolph S. E. Mortality rate and population density of tsetse flies correlated with satellite imagery. Nature 1991;351:739-741.
Ford J. & Clifford H. R. Changes in the distribution of cattle and bovine trypanosomiasis associated with the spread of tsetse-flies (Glossina) in south-west Uganda. Journal of Applied Ecology 1968;5:301-337.
Wint W. & D. B. Anthropogenic and Environmental Correlates of Livestock Distribution in Sub-Saharian Africa. A Comparative Analysis of Livestock Surveys in Mali, Niger, Nigeria, Sudan et Tchad. 1994; L. The Overseas Development Administration, United Kingdom.
Hendrickx G., Napala A., Slingenbergh J. H. W., De Deken R. & Rogers D. J. A contribution towards simplifying area-wide tsetse surveys using medium resolution meteorological satellite data. Bulletin of Entomological Research 2001;91:333-346.
de La Rocque S. Identification des facteurs discriminants de la présence de glossines dans une zone agro-pastorale du Burkina Faso. Intérêt pour l'évaluation du risque trypanosomien. 1997; F. p. Thesis University of Montpellier II.
Lefrançois T., Solano P., de La Rocque S., Bengaly Z., Reifenberg J. M., Kabore I. & Cuisance D. New epidemiological data on Animal Trypanosomosis by molecular analysis in the pastoral zone of Sidéradougou, Burkina Faso. Molecular Ecology 1998;7:897-904.
de La Rocque S., Michel J. F., Cuisance D., De Wispeleare G., Augusseau X., Guillobez S. & Arnaud M. Le risque trypanosomien, une approche globale pour une décision locale. 2001; M. CIRAD Edition, France, 152 pp.
Michel J. F., Michel V., de La Rocque S., Touré I. & Richard D. Modélisation de l'occupation de l'espace par les bovins. Applications à l'épidémiologie des trypanosomoses animales. Revue d'Elevage et de Médecine Vétérinaire des Pays tropicaux 1999;52:25-33.
Michel J. F., Dray S., de La Rocque S., De Wispelaere G., Desquesnes M., Solano P. & Cuisance D. Modelling bovine trypanosomosis spatial distribution by GIS in an agro-pastoral zone of Burkina Faso. Preventive Veterinary Medicine 2002;56:5-18.
Bouyer J. Etude de la distribution des glossines dans un bassin en transformation : cas du Mouhoun au Burkina Faso. Master in Parasitology, University of Montpellier II, France, 42 pp. 2002; 42 p.
Van den Bossche P., Shumba W. & Makhambera P. The distribution and epidemiology of bovine trypanosomosis in Malawi. Veterinary Parasitology 2000;88:163-176.
Van den Bossche P. & Vale G. A. Tsetse and Trypanosomosis in Southern Africa. 2000; Z. Harare RTTCP, 147 pp.
Sigauque I., Van den Bossche P., Moiana M., Jamal S. & Neves L. The distribution of tsetse (Diptera: Glossinidae) and bovine trypanosomosis in the Matutuine District, Maputo Province, Mozambique. Onderstepoort Journal of Veterinary Research 2000;67:167-172.
Van den Bossche P. Some general aspects of the distribution and epidemiology of bovine trypanosomosis in southern Africa. International Journal of Parasitology 2001;31:592-598.
Hendrickx G., de La Rocque S., Reid R. & Wint W. Spatial trypanosomosis management: From data-layers to decision making. Trends in Parasitology 2001;17:35-41.
Rogers D. J. A general model for African Trypanosomiasis. Parasitology 1988;10:193-212.
Rogers D. J. A general model for tsetse populations. Insect Science and its Application 1990;11:331_346.
Wacher T. J., Rawlings P. & Snow W. F. Cattle migration and stocking densities in relation to tsetse-trypanosomiasis challenge in The Gambia. Annals of Tropical Medicine and Parasitology 1993;87:517-524.
Barnsley M. F. Fractals Everywhere. 1993; 2nd ed. Academic Press Professional.Boston, United States,
Mallat S. A Wavelet Tour of Signal Processing. 1999;
Burel F. & Baudry J. Ecologie du paysage. Concept, méthodes et applications. 1999; P. Edition Tec & Doc, France, 348 p.
Rogers D. J. & Randolph S. E. Population ecology of tsetse. Ann. rev. entomol. 1985;30:197-216.
Saunders D. S. Determination of physiological age for female Glossina morsitans. Nature 1960;186:651.
Challier A. Amélioration de la méthode de détermination de l'âge physiologique des glossines. Bulletin de la Société de Pathologie Exotique 1965;58:250-259.
Jackson C. H. N. An artificially isolated generation of tsetse flies. Bulletin of Entomological Research 1946;37:291-299.
Borne F., Petiteau L., Geoffroy B., De La Rocque S. & Cuisance D. Fly Picture Measurement, un nouvel outil informatique pour l'étude des glossines. Revue d'Elevage et de Médecine Vétérinaire des pays Tropicaux 1999;52:19-21.
Clausen P. H., Adeyemi I., Bauer B., Breloeer M., Salchow F. & Staak C. Host preferences of tsetse (Diptera : Glossinidae) based on bloodmeal identifications. Medical and veterinary Entomology 1998;12:169-180.
Lloyd L. L. & Johnson W. B. The trypanosome infections of tsetse flies in Northern Nigeria and a method of estimation. Bulletin of Entomological Research 1924;14:225-227.
Van den Bossche P., Doran M. & Connor R. J. An analysis of trypanocidal drug use in the Eastern Province of Zambia. Acta Tropica 2000;75:247-258.
Hendrickx G. A geo-referenced decision support methodology towards trypanosomosis managment in West Africa. 1999; U. o. G. Thesis, Gent, Belgium,.176 pp.
Erkelens A. M. Selection of priority areas for tsetse control in Africa; a decision tool using GIS in Didessa Valley, Ethiopia, as a pilot study. 2000; I. A. E. A. n: Animal Trypanosomosis: Diagnosis and Epidemiology, Vienna, Austria (Backhuys Publishers, Leiden, The Netherlands), 213-236.
Doran M. & Van den Bossche P. SITE Analysis. An approach to strategy formulation for tsetse and trypanosomosis control. Bovine trypanosomosis in Southern Africa. 2000; H. Volume 1. Regional Tsetse and Trypanosomosis Control Program for Southern Africa, Zimbabwe, 74 pp.
Geerts S., Holmes P. H., Diall O. & Eisler M. C. African bovine trypanosomiasis: the problem of drug resistance. Trends in Parasitology 2001;17:25-28.
Brightwell R., Dransfield R., Maudlin I., Stevenson P. & Shaw A. Reality vs. rhetoric - a survey and evaluation of tsetse control in East Africa. Agriculture and Human Values 2001;18:219-233.
de La Rocque S., Yoni W., Balenghien T., Bouyer J., Kaboré I., Desquesnes M. & Kamuanga M. Integrated and targeted campaign against riverine tsetse flies in Burkina Faso. 2004; P. 28th ISCTRC Conference, South Africa, 29 sept - 3 oct 2003. Ed. OUA-STRC: Nairobi, Kenya.
Q12 Impact, timeline and milestones
|(a) |Impact |
| |Briefly describe how and when the results of your application will be translated into practical benefits for those in the developing |
| |world. |
| | |
|The project will reach its objectives through the five common principles applicable to developing countries, namely genuine and equitable |
|partnerships, interdisciplinary approaches, use of Information and Communication Technologies (ICTs), investments in human capital, and effective|
|communication with decision makers and stakeholders. In both study areas (Burkina Faso and Zambia), the field research will be conducted by local|
|scientists, assisted by their technical staff, in the natural environment. The close collaboration between European-based research institutes |
|and the local scientists will facilitate the transfer of knowledge and research findings throughout the duration of the project. At the end of |
|the project, research findings will be summarised in simple and practical guidelines. The guidelines will make it possible for those responsible |
|for trypanosomiasis control in tsetse-infested developing countries to optimise trypanosomiasis control strategies and facilitate the selection |
|of priority areas for control by including the local environmental conditions in their decisions. Appreciation of the local environment will be |
|based on remotely sensed data that are readily available and certain physiological parameters of the tsetse population that can be measured |
|easily. Hence, the findings of the research project are likely to have an immediate impact on decision making for control. Since the project |
|areas represent the two main ecological settings (savannah and riparian vegetation), findings can be transferred easily to similar regions. The |
|proposed project does not aim at developing new control tools. On the contrary, its findings will improve the efficacy of existing control tools.|
|Indeed, the project’s outcomes will make it possible to identify areas where the impact of the intervention is expected to be highest or, in some|
|cases, permanent. Furthermore, the choice of the most appropriate control method or combination of control methods will make it possible to |
|achieve more with less effort. Considering this improved effectiveness it is expected that uptake of the research findings by the stakeholders |
|(e.g. livestock keepers, farmers and people living in areas where human sleeping sickness is endemic), who are already acquainted with the |
|currently available trypanosomiasis control methods, will be immediate. |
| | |
|(b) |Timeline and milestones |
| |Provide a timeline indicating at least one key milestone per year. This should include the method of reporting to allow the achievement of|
| |the milestone to be evaluated by peer review. Grant recipients will be asked to report against the milestones. |
| | |
|The deliverables of the project are listed below and milestones are illustrated in the timetable. |
|Workplan 1: inventory of existing data – collection of additional data where necessary (e.g. tsetse surveys) - environmental clusters mapping - |
|retrospective studies of human encroachment and habitat fragmentation –identification of study sites around month 10. |
|Workplan 2: tsetse collections - analyse of physiological parameters development of population dynamics and viability models for each study sites|
|Workplan 3: tsetse dispersal assessment and modelling - description of inter/intra subpopulation genetic diversity. |
|Workplan 4- determination of host preference - analyse of trypanosomes in infection rate of tsetse flies– livestock census and livestock movement|
|patterns - trypanosomiasis surveillance. |
|Workplan 5: -development of spatial biological model and R0 map. |
|Workplan 6: - trypanosomiasis management practices survey - determination of the appropriateness of the current management practices. |
|Workplan 7: assessment of the appropriateness of various control interventions - development and transfer of guideline for appropriate integrated|
|T&T control protocols |
Q13 Details of knowledge transfer
Include (where applicable): (a) Dissemination of research outcomes to specified target audiences and proposed delivery pathways; (b) Ancillary activities related to the research that will facilitate delivery and uptake of research products/outcomes; (c) Proposed methods of measuring the uptake of end products by the institutions and/or livestock keepers involved; (d) If any, additional research and education and training that is not included in the research project, but is considered necessary to translate research products into practical benefits.
Besides the guidelines that will be produced and distributed widely at the end of the project, other channels will be used to ensure exploitation, dissemination and optimal use of the project’s outcomes beyond the existence of the project. The tsetse and trypanosomiasis field benefits from a number of organisations that are in an ideal position to disseminate and exploit the outcome of the proposed project.
An important player is the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC), a concerted initiative of the African Union (AU) Member States. The campaign is a collective and co-ordinated effort of African tsetse-infested countries and is co-ordinated by the PATTEC Co-ordination Office. The PATTEC Co-ordination Office has been mandated to assist countries with their planning for tsetse and trypanosomiasis control and will provide countries with the necessary tools to support planning. Hence, the PATTEC Co-ordination Office will facilitate transfer of the guidelines produced by the project and ensure assistance with the use of the guidelines.
Another organisation that, for many years, has been instrumental in the dissemination of information regarding tsetse and trypanosomiasis and that will be used to disseminate the outcomes of the project is the Programme Against African Trypanosomiasis (PAAT). The PAAT forms the umbrella for an inter-agency alliance comprising FAO, IAEA, WHO, AU/IBAR, research institutions, field programmes, NGOs and donors, with the overall goal to improve the livelihood of rural people in the 37 tsetse affected countries of sub-Saharan Africa. It provides a normative and advisory role on all aspects of the implementation of the PATTEC initiative. The Panel of PAAT Advisory Group (PAG) Coordinators provides information on specific fields of expertise and research development, technical and institutional proposals for consideration by the PAAT Committee. The involvement of several of the applicants in the PAAT will ensure the transfer of the project’s outcomes to the planners.
The project will also benefit from the PAAT-Information System (PAAT-IS). The PAAT-IS represents a neutral mechanism and forum for tsetse-infested countries to contribute and benefit on an equal basis from the information exchange. Also, PAAT-IS serves to address the issue of quality of information, its derivability and preservation, efficient flow, timeliness, consistency and coordination. The PAAT-IS will be used as an instrument for the dissemination of project results.
Finally, where possible, project’s outcomes will be published in the scientific literature or will be presented during scientific or technical meetings such as the biannual meeting of the International Scientific Council for Trypanosomiasis Research and Control (ISCTRC) of the AU/IBAR or meetings of the Association of Institutions for Tropical Veterinary Medicine (AITVM).
|Q14 |Research on human participants or human tissue | |
| | | |
| (a) |Does your project involve the use of human participants or human tissue? |YES | |NO |X |
| |If yes, refer to notes. |
| |If the project includes studies on patients being cared for by the NHS, please also answer Q13. |
|(b) |Does your project involve the use of human participants or other human tissue, outside the UK? |YES | |NO |X |
| | | | | | |
| |If yes, refer to notes. | |
|(d) |Does your proposal involve research on gene therapy which requires regulatory approval? |YES | |NO |X |
| |If yes, refer to notes. | |
Q15 Experiments on animals
|Do your proposals involve the use of animals or animal tissue? |YES | |NO |X |
| | | | | | |
|(a) |Do your proposals include procedures to be carried out on animals in the UK which require a Home Office licence?|YES | |NO | |
| | | | | | |
| |If yes, refer to notes | | | | |
| | | | | | |
|(b) |Does the institute where the animal work is to be carried out hold a certificate of designation under the |YES | |NO | |
| |Animals (Scientific Procedures) Act 1986 | | | | |
| | | | | | |
| | | | | | |
|(c) |Do your proposals involve the use of animals or animal tissue outside the UK? |YES | |NO | |
| |If yes, refer to notes |
Q16 Commercial exploitation
|(a) |Will the proposed research use technology, materials or other invention that, as far as you are aware, are |YES | |NO |X |
| |subject to any patents or other form of intellectual property protection? | | | | |
| | | | | | |
| | | |
If yes, give brief details and indicate what arrangements are in place for the use, management and exploitation of such background intellectual property.
| |
|(b) |What arrangements have been, or are intended to be, put in place between collaborating researchers and institutions named on this form for |
| |the management of intellectual property arising out of the research which is the subject of this application? Please give details and attach |
| |any relevant agreements, undertakings or statements of understanding. |
|In order to motivate the members to cooperate for the common good, and for the productivity of the Project, the Principal applicant will identify all|
|intellectual property (IP) brought to the project as pre-existing know-how and organise all the IP issues of management on the following principles: |
|(i) Pre-existing data stay the propriety of the institution of origin; If requested; particular permission has to be written by the applicant who |
|agree to share its pre-existing data; in addition, the traceability of the data will be guaranteed; (ii) knowledge resulting from the project shall |
|be the property of the applicant generating it; (iii) every applicant enjoys, strictly for the project purposes, free access to another applicant’s |
|knowledge, data and know-how; (iv) Project’s end products will be public and free access and (v) disputes will be resolved by the Principal Applicant|
|in the best project interest. |
|(c) |Is the proposed research, in whole or in part, subject to any agreements with commercial, academic or other |YES | |NO |X |
| |organizations? | | | | |
| | | | | | |
| |If YES, give brief details. | |
| |
|(d) |Is the proposed research likely to lead to any patentable or commercially exploitable results? |YES | |NO |X |
| |If YES, give brief details. | |
| |
|(e) |If any potentially commercially exploitable results may be based upon tissues or samples derived from human |YES | |NO |X |
| |participants, please confirm that there has been appropriate informed consent for such use. | | | | |
| | | | | | |
| |
Q17 Consultancies and equities
|Do any of the applicants have consultancies or any equity holdings in companies or other organizations that might have an |YES | |NO |X |
|interest in the results of the proposed research? | | | | |
| | | | | |
| | |
If yes, refer to Guidance Notes and give brief details.
| |
|Q18 |Related applications and research time |
|(a) |Is this or a related application currently being submitted elsewhere? |YES | |NO |X |
| | | | |
| |If yes, to which organization? | |
| | | |
| |By what date is a decision expected? (dd/mm/yyyy) | |
| | | |
|(b) |Has this, or a similar, application been submitted elsewhere over the past year? |YES |X |NO | |
| | | |
| |If yes, to which organization? | FP6-2002-INCO-DEV strep, EU |
| | | |
| |What was the result? | negative: should be placed in a development programme |
| | | |
|(c) |Is this application a resubmission of an application previously considered by the Trust? |YES | |NO |X |
| | | |
| |If yes, when was it originally considered and what was the Trust’s reference number? | |
| | | |
| |In a covering letter, briefly state how this application differs from the original |
| | |
|(d) |What proportion of working time do the Principal, Joint and Coapplicant(s) spend on research? (%) |
| | |
| |Principal applicant: 50% Co-applicant 4: 25% Co-applicant 8: 60% |
| |Joint applicant 1: 40% Co-applicant 5: 50% Co-applicant 9: 80% |
| |Joint applicant 2: % Co-applicant 6: 90% |
| |Joint applicant 3: 70% Co-applicant 7: 80% |
| | |
| | |
| |What proportion of this time will be spent on the project by the Principal, Joint and Coapplicant(s)? (%) |
| | |
| |Principal applicant: 40% Co-applicant 4: 35% Co-applicant 8: 30% |
| |Joint applicant 1: 40% Co-applicant 5: 35% Co-applicant 9: 35% |
| |Joint applicant 2: % Co-applicant 6: 60% |
| |Joint applicant 3: 50% Co-applicant 7: 25% |
| | | | | | |
|(e) |Will the research project be undertaken in a Wellcome Trust Clinical Research Facility? |YES | |NO |X |
| | | |
| |If yes, please specify: | |
| | | |
| | | |
|(f) |Will the research project be undertaken in a Wellcome Trust Centre/Tropical Major Overseas Programmes? |YES | |NO |X |
| | | | | | |
| |If yes, this application should be accompanied by a letter of support from the Director of the Centre/Programme. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |DE LA ROCQUE |Date of birth: |17-08-1966 |
| | | | | |
| |Forenames: |Stephane |Nationality: |French |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|PHD in Parasitology (University of Montpellier, 1997); MSc of Parasitology (University of Montpellier, 1994); Diploma in medical statistic (CESAM) |
|(University of Paris VI, 1993); Diploma in Tropical Animal Health (University of Creteil, 1992); doctor in Veterinary Medicine (School of Lyon, 1991).|
| |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Head of the Vectorial diseases Unit |
| | | | | |
| |Department: |EMVT |
| | | | | |
| |Institution: |CIRAD (cirad.fr) |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |12-01-98 - date |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
| CIRAD-EMVT, Montpellier, France |
| | | | | |
|(e) |Source of personal salary support |Cirad |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|Cirad-Emvt, Institut Pasteur, Cayenne, French Guiana, 01/06/1991 – 30/06/94: |
|Epidemiology of animal hemoparasites in the Guianas |
| |
|Cirad-Emvt & French Ministry of Research, Cirdes, Burkina Faso, 01/09/94 – 31/02/2002 |
|Epidemiology and risk assessment for tsetse and Animal trypanosomosis in sub-Saharan areas |
| |
|Cirad-Emvt, IRSA Dakar, Senegal, 31/02/2002 – 30/06/2004 |
|Ecology of emerging disease (Bluetongue, West Nile, Rift Valley fever) |
| |
|Cirad-Emvt, Montpellier, France, 30/06/2004 |
|General Coordinator of the 6th PCRDT UE Integrated Project ‘EDEN” (Emerging Disease in a changing European Environment) |
| |
| |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
|Tsetse & tryps control fields protocols in collaboration with pharmaceutical industry |
| |
|Epidemiosurveillance networks for Bluetongue and West Nile in the South of France & recommendations to decision makers (expert groups) |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|General Coordinator of the 6th UE PCRDT Integrated Project “EDEN (Emerging Disease in an European Changing World)” |
|Expert in the Paat Advisor Group (Programme Against African Trypanosomosis, OMS, FAO, IAEA, OUA) |
|Main regular training courses : Master internacionale en enfermedads parasitias tropicales, Facultdad de Farmacia, Valencia, Spain : tsetse & African |
|trypanosomosis - Pasteur Institute, Paris: 3 cessions : Satellites and epidemiology, Environmental changes and eco-epidemiology, Tsetse & African |
|trypanosomosis - Veterinary School of Toulouse : geographical information systems for epidemiology . |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
|Rioux, J. A. and S. de La Rocque (2003). "Climat, leishmanioses et trypanomosomes. In: Changement Climatique, maladies infectieuses et allergiques. |
|Annales de l'Institut Pasteur, 41-62. |
|de La Rocque, S., Pin, R, Michel, V. 2003. Remote sensing and epidemiology: examples of applications for two vector-borne diseases. Comparative |
|Immunology, Microbiology and Infectious Diseases. in press |
|de La Rocque, S., Michel, J.F., Cuisance, D., de Wispelaere, Solano, P., Augusseau, X. G., Arnaud, M., Guillobez, S. 2001. Le risque trypanosomien : |
|une approche globale pour une décision locale. Edition du Cirad, 152 p. |
|de La Rocque, S., Michel, J.F. & Cuisance, D. 2001 . L'apport des SIG pour l'étude de l'épidémiologie des trypanosomoses animales. Médecine tropicale,|
|4-5 : 61 : 365-71 |
|Michel, J.F., Dray, S, de La Rocque, S., Desquesnes, M., Solano, P., de Wispelaere, G. & Cuisance, D. Modelling bovine trypanosomosis spatial |
|distribution by GIS in an agro-pastoral zone of Burkina Faso. Prev. Med Vet, 56(1): 5-18 |
|de La Rocque, S., Michel, J.F., de Wispelaere, G. & Cuisance, D. 2001. De nouveaux outils pour l'étude des trypanosomoses animales en zone soudanienne|
|: Modélisation de paysages épidémiologiquement dangereux par télédétection et systèmes d'information géographique. Parasite, 8 (3): 171-95 . |
|Hendrickx, G., de La Rocque, S., Reid, R. & Wint, W., 2001, Spatial trypanosomosis management: From data-layers to decision making. Parasitology |
|Today, 17 (1): 35-41. |
|de La Rocque, S., Augusseau, X., Guillobez, S., Michel, V., De Wispelaere, G., Bauer, B. & Cuisance, D. 2001. The changing distribution of two |
|riverine tsetse flies over 15 years in an area increasingly occupied by agriculture in Burkina Faso. Bulletin of Entomological Research. 91(3): |
|157-166. |
|de La Rocque, S, Bengaly, Z., Michel, J.F., Solano, P., Sidibé, I. & Cuisance, D. 1999. Importance spatiale et temporelle des interfaces |
|bovins-glossines dans la transmission de la trypanosomose animale en Afrique de l’Ouest. Revue d’Elevage et de Médecine Vétérinaire des Pays |
|tropicaux. 52 (3-4): 215-222. |
|Solano, P., de La Rocque, S., Cuisance, D., Geoffroy, B., de Meeus, T., Cuny, G. & Duvallet, G. 1999. Intraspecific variability in natural population |
|of Glossina palpalis gambiensis from West Africa, revealed by genetic and morphometric analyses. Med. Vet. Entomol, 13 : 401-407. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |VAN DEN BOSSCHE |Date of birth: |16-03-1962 |
| | | | | |
| |Forenames: |Peter |Nationality: |Belgian |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|Diplomate of the European Veterinary Parasitology College, 2003, PHD in Parasitology, University of Pretoria, 2000; Diploma in Tropical Anipmal Health|
|and Produciton, Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium, 1987; Doctor in Veterinary Science, Ghent University, 1985. |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Research Scientist |
| | | | | |
| |Department: |Department of Animal Health |
| | | | | |
| |Institution: |Prince Leopold Institute of Tropical Medicine |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |15-09-2000 |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
| Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium |
| | | | | |
|(e) |Source of personal salary support |Prince Leopold Institute of Tropical Medicine |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|Research Scientist, Protozoology Unit, Prince Leopold Institute of Tropical Medicine, Belgium: 2000- |
| |
|Technical Co-ordinator, Regional Tsetse and Trypanosomiasis Control Programme for southern Africa, Zimbabwe: 1994-2000 |
| |
|Research Scientist, Belgian Animal Disease Control Programme, Zambia: 1989-1994. |
| |
| |
| |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
|National Strategic Plans for the control of tsetse-transmitted trypanosomiasis for Malawi, Zambia, Zimbabwe and Mozambique. |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|Involvement in the research programme of the Protozoology Unit of the Department of Animal Health of the Prince Leopold Insitute of Tropical Medicine.|
|Lecturing : |
|Veterinary Protozoology and ectoparasitology, University of Pretoria, (7 days) |
|International course in tropical animal health, Prince Leopold Insitute of Tropical Medicine, tsetse and trypanosomiasis (14 days) |
|Course in Tropical Animal Health, Utrecht University, The Netherlands, tsetse and trypanosomiasis (1 day) |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
| |
|Van den Bossche,P. & De Deken,R. (2004) The application of bait technology to control tsetse. In: The Trypanosomiases (Ed. by I.Maudlin & P.Holmes), |
|pp. 515-522. CAB International. |
|Connor,R.J. & Van den Bossche,P.(In press) African animal trypanosomoses. In: Infectious Diseases of Livestock (Ed. by J.A.W.Coetzer, G.R.Thomson & |
|R.C.Tustin). |
|Van den Bossche,P., Thys,E., Elyn,R., Marcotty,T. and Geerts,S. (In press) The provision of animal health care to African smallholders. An analytical |
|approach. Revue Scientifique technique de l'office International des Epizooties. |
|Van den Bossche, P. and De Deken, R. (2002) Seasonal variations in the distribution and abundance of Glossina morsitans morsitans Westwood in a |
|cultivated area of eastern Zambia. Medical and Veterinary Entomology 16, 170-176. |
|Van den Bossche,P. (2001) Some general aspects of the distribution and epidemiology of bovine trypanosomosis in southern Africa. International Journal|
|for Parasitology 31, 592-598. |
|Van den Bossche,P. & Vale,G.A. (2000) Tsetse and Trypanosomosis in Southern Africa. Harare: RTTCP, 147pp.. |
|Van den Bossche,P., Doran,M. & Connor,R.J. 2000. An analysis of trypanocidal drug use in the Eastern Province of Zambia. Acta Tropica 75, 247-258. |
|Van den Bossche,P., Shumba,W. & Makhambera,P. (2000) The distribution and epidemiology of bovine trypanosomosis in Malawi. Veterinary Parasitology 88,|
|163-176. |
|Van den Bossche, P. and Hargrove, J.W. (1999) Seasonal variation in nutritional levels of male tsetse flies Glossina morsitans morsitans Westwood |
|(Diptera: Glossinidae) caught using fly-rounds and electric screens. Bulletin of Entomological Research 89, 381-387. |
|Van den Bossche, P. and Staak, C. (1997) The importance of cattle as a food source for Glossina morsitans morsitans Westwood (Diptera: Glossinidae) in|
|Katete District, Eastern Province, Zambia. Acta Tropica, 65:105-109. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |ROGERS |Date of birth: | |
| | | | | |
| |Forenames: |David john |Nationality: |British |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| |
|1964-67 - Oxford University, UK (St. Peter's College), Zoology, BA(Oxon) |
|1967-70 - Oxford University, UK (St. Peter's College), Entomology , D.Phil. (Oxon) |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Professor, TALA Research |
| | | | | |
| |Department: |Ecology Department |
| | | | | |
| |Institution: |Oxford university, U.K. |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |1964 |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
| University |
| | | | | |
|(e) |Source of personal salary support |University |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|1970 -72: Wellcome Trust Research Grant |
| |
|1972-date: University Lecturer, Department of Zoology, Oxford |
| |
|1999 - date Professor of Ecology, University of Oxford |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
|Editorial Boards of Journal of Animal Ecology and Medical and Veterinary Entomology |
|Consultancies for UK Department for International Development (DFID), World Health Organisation (WHO), Food & Agriculture Organisation (FAO), |
|International Atomic Energy Agency (IAEA), International Fund for Agricultural Development (IFAD), World Wildlife Fund (WWF), National Aeronautics and|
|Space Administration (NASA) Interagency Research Partnership for Infectious Diseases (INTREPID) program. |
|Expert Committee Member for FAO, Joint FAO/IAEA Division, WHO, IUCN |
|Contributions to WWF Report on the Impact of Climate Change in Southern Africa (1996) and Health Report for UK Climate Impacts Program (2000). |
|Chair, Scientific Committee of EDEN (Emerging Diseases European Network) to investigate health impacts of environmental changes in Europe. |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|6th PCRDT EU Integrated Project EDEN, 2004-2009: Chairman of the Steering Committee |
|NY01, NIAID, 2002 – 2007, Laura Kramer NYSDoH, USA: Habitat identification of West Nile Virus vectors in the NY State. Total Grant (subcontract) to |
|TALA Research/DJR $~100,000 over 5 years. |
|ISU01, NIH, 2002 – 2007, Elliot Krafsur Iowa State University Relating tsetse genomics and physiology to environmental variables. Total Grant |
|(subcontract) to Oxford University/DJR ~$60,000 over 3 years. |
|Wellcome01, 2002-2004, Exploring the use of oceanographic analytical techniques for studying disease epidemiology. Total Grant to Oxford |
|University/DJR £125,000 over 2 years. |
|TBA, DFID/DEFRA, Matthew Baylis/IAH. Assessing the risks of new viral disease arrival in the UK Total grant (subcontract) to Oxford University/DJR c.|
|£160,000 over 3 years. |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
|Rogers, D.J. & Randolph, S.E. (1991). Mortality rates and population density of tsetse flies correlated with satellite imagery. Nature 351, 739-741.|
|Rogers, D.J. & Randolph, S.E. (1993). Distribution of tsetse and ticks in Africa: past, present and future. Parasitology Today 9, 266-71. |
|Hay, S.I., Tucker, C.J., Rogers, D.J. & Packer, M.J. (1996) Remotely sensed surrogates of meteorological data for the study of the distribution and |
|abundance of arthropod vectors of disease. Annals of Tropical Medicine and Parasitology 90, 1-19. |
|Rogers, D.J., Hay, S.I. & Packer, M.J. (1996) Predicting the distribution of tsetse flies in West Africa using temporal Fourier processed |
|meteorological satellite data. Annals of Tropical Medicine and Parasitology 90, 225-241. |
|Rogers, D.J., Hay, S.I., Packer, M.J. & Wint, G.R.W. (1997) Mapping land-cover over large-areas using multispectral data derived from the NOAA-AVHRR: |
|a case study of Nigeria. International Journal of Remote Sensing 18, 3297-3303. |
|Hendrickx, G., Napala, A., Slingenbergh, J.H.W., De Deken, R., Vercruysse, J. & Rogers, D.J. (2000). The spatial patterns of trypanosomiasis |
|predicted with the aid of satellite imagery. Parasitology 120, 121-134. |
|Rogers, D.J. (2000) Satellites, space, time and the African trypanosomiases. Advances in Parasitology 47, 129-171. |
|Hay, S.I., Randolph, S.E. & Rogers, D.J. (eds.) (2000) Remote Sensing and GIS in Epidemiology. Academic Press, London. |
|Rogers, D.J. & Randolph, S.E. (2002). A response to the aim of eradicating tsetse from Africa. Trends in Parasitology 18, 534-536. |
|Rogers, D.J. & Robinson, T.P. (2004). Tsetse Distribution. Chapter in a Trypanosomiasis Textbook (ed. Maudlin, I, Holmes, P. & Miles, M.). CAB |
|publishers (in press). |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |MUBANGA |Date of birth: |03-11-1963 |
| | | | | |
| |Forenames: |Joseph |Nationality: |Zambian |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|Bachelor of Veterinary Medicine Degree (BVM), University of Zambia, 1989. Master of Veterinary Medicine degree, University of Glasgow, 1997. |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Chief Tsetse Control Biologist |
| | | | | |
| |Department: |Department of Veterinary and Livestock Development |
| | | | | |
| |Institution: |Ministry of Agriculture and Co-operatives, Zambia |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |09-2003 |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|Ministry of Agriculture and Co-operatives, Zambia |
| | | | | |
|(e) |Source of personal salary support |Government of Zambia |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|Principal Tsetse Control Biologist, Regional Tsetse and Trypanosomiasis Control Programme, 1997-2001. |
| |
|Acting Chief Tsetse Control Biologist, Department of Research and Specialist Services, Ministry of Agriculture and Cooperatives, 2001-2003. |
| |
|Chief Tsetse Control Biologist, Department of Veterinary and Livestock Development, 2003 - to date. |
| |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
|Development of Zambian National Strategic Plan for the control of tsetse-transmitted trypanosomiasis. |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|Administration: |
|Formulation of annual workplans and budgets for tsetse control. |
|Formulation of trypanosomiasis and Tsetse private contracts. |
|Monitoring and supervision of tsetse control activities carried out by private contractors and community-based tsetse control activities in the |
|country. |
|Compilation of monthly and annual reports. |
| |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
| |
|Sinyangwe,L., Delespaux,V., Brandt,J., Geerts,S., Mubanga,J., Machila,N., Holmes,P.H. & Eisler,M.C. 2004. Trypanocidal drug resistance in eastern |
|province of Zambia. Veterinary Parasitology 119, 125-135. |
|Mubanga, J., Mangani, P. & Chivweta, A. 2002. Social-economic study on the Choma-Kalomo Aerial Spray Tsetse Control operation of 1987. Report to FAO, |
|Lusaka. |
|Machila,N., Sinyangwe,L., Mubanga,J., Hopkins,J.S., Robinson,T. & Eisler,M.C. 2001. Antibody-ELISA seroprevalence of bovine trypanosomosis in the |
|Eastern Province of Zambia. Preventive Veterinary Medicine 49, 249-257. |
|Van den Bossche,P., Mudenge,D., Mubanga,J. & Norval,A. 1999. The parasitological and serological prevalence of tsetse-transmitted bovine |
|trypanosomosis in the Eastern Caprivi (Caprivi District, Namibia). Onderstepoort Journal of Veterinary Research 66, 103-110. |
|Lumamba, D., Mweempwa, C., Mubanga, J. and Leroy, E. (1997) Eradication of Glossina morsitans morsitans and Glossina pallidipes in the Kariba Hills of|
|Siavonga, southern Zambia. Proceedings of the 24th meeting of the International Council for Trypanosomiasis Research and Control (ISCTRC), Maputo, pp |
|427-431. |
|Mubanga, J. 1996. Studies on Chemoprophylaxis of Trypanosomosis using a competitive enzyme immunoassay for the detection of isometamidium and homidium|
|in cattle and sheep. MVM Thesis. University of Glasgow, Glasgow. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |Matjila |Date of birth: |10-07-1972 |
| | | | | |
| |Forenames: |Tshepo Paul |Nationality: |South African |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|BSc, BSc zoology (Hons) Medical University of South Africa 1996; MSc (Veterinary Science) University of Pretoria 2000. |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Lecturer |
| | | | | |
| |Department: |Veterinary Tropical Diseases |
| | | | | |
| |Institution: |University of Pretoria |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |01-11-2002 |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|University of Pretoria |
| | | | | |
|(e) |Source of personal salary support |University of Pretoria |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|1-11-1998 to 30-10-2002. Post held: Technician. Dept: Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria. |
|1-11-2002 to date. Post held: Lecturer. Dept: Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria. |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|Teaching: |
|Teaching ectoparasitology and protozoology to first year veterinary nursing students and third year veterinary students. |
|Administration: |
|Annual applications to the National Research Fund for research funding. |
|Academic administration of final veterinary student refresher course program. |
|Bi-annual administration of the performance management contract |
|Drafting of financial reports in research project |
|Manager of the Tsetse/Tryps unit in the Dept. of Veterinary Tropical Diseases. |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
| |
|Matjila PT, Penzhorn BL, Bekker CP, Nijhof AM, Jongejan F. 2004 Confirmation of occurrence of Babesia canis vogeli in domestic dogs in South Africa. |
|Veterinary Parasitology 122, 119-25. |
|Matjila PT, Penzhorn BL. 2002. Occurrence and diversity of bovine coccidia at three localities in South Africa. Veterinary Parasitology 104, 93-102. |
| |
| |
| |
| |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: | SIDIBE |Date of birth: |02/20/1958 |
| | | | | |
| |Forenames: | Issa |Nationality: |Burkinabe |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|PhD, Parasitology, University of montpellier II, France, december 1996 |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Head of Unit (URBIO) |
| | | | | |
| |Department: |Biological and Integrated Control Unit (URBIO) |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |2003-permanent |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|Government of Burkina Faso |
| | | | | |
|(e) |Source of personal salary support |National Research Budget and CIRDES |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid |- |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
|Head of Biological Control Unit (URBIO): since jun 2003 |
|Regional Coordinator of Animal Production systems from 01/10/2000 to 31/03/2005 |
|Head of Epidemiology Unit : May-97 to 01/12/1998 |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|Head of a team of researchers |
|Member of the PAAT (Programme Against African Trypansomosis) Advisory Group |
|Member of the executive committee of the International Scientific Council for Trypanosomosis Research and Control (ISCTRC)- Chairman from 2001 to |
|2003. |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
|I. Sidibé (1996)Variabilité génétique de Trypanosoma congolense, agent de la trypanosomose animale : Implications taxonomiques et épidémiologiques. |
|Rapport de thèse de doctorat de Sciences de la faculté des Sciences et techniques du Languedoc. Université de Montpellier II. pp 120. |
|Clausen P.-H., Leendertz F.H., Blankenburg A., Tietjen U., Mehlitz D., Sidibe I. and Bauer B. (1999) A Drug Incubation Glossina Infectivity Test |
|(DIGIT) to assess the susceptibility of Trypanosoma congolense bloodstream forms to trypanocidal drugs (Xenodiagnosis). Acta Tropica 72 (1) : 111-117 |
|. |
|S. De La Rocque, Z. Bengaly, J.F. Michel, P. Solano, I. Sidibe, D. Cuisance (1999).Importance des interfaces spatiales et temporelles entre les bovins|
|et les glossines dans la transmission de la trypanosomose animale en Afrique de l’Ouest. Revue Elev. Méd. Vét. Pays trop., 1999, 52 (3-4) : 215-222. |
|J.J. McDermott, I. Sidibe, B. Bauer, B. Diarra, P-H. Clausen, T. Woitag, D. Ouedraogo, A. Peregrine, M. Eisler, and D. Mehlitz (2000)Field studies on |
|the development and impact of drug resistant animal trypanosomes in market-oriented production systems in the southern Guinean Zone of West Africa. |
|Newsletter on Integrated Control of Pathogenic Trypanosomes and their Vectors, N°2, April 2000; p.18-21 |
|I. Sidibé, B. Bauer, P-H. Clausen, B. Diarra, T. Woitag, D. Ouédraogo, J. McDermott, A. Peregrine, M.C. Eisler, M. Kamuanga, N. Boly, S. M. Touré. |
|Etude de la résistance aux médicaments utilisés dans le traitement des trypanosomoses animales au Kénédougou, Burkina Faso. Actes 4è édition du Forum |
|National de la Recherche Scientifique et des Innovations Technologiques (FRSIT), Ouagadougou, 3 au 8 Avril 2000., tome 2 : p.67-74 |
|Eisler, M.C. ; Brandt, J. ; Bauer, B.; Clausen,P.H.; Delespaux, V.; Holmes, P.H.; Ilemobabe, A.S.; Machila, N., Mbwambo, H. ; MCDermott, J. ; Mehlitz,|
|D. ; Murila, G. ; Ndung’u, J.M. ; Peregrine, A.S. ; Sidibé, I. ; Sinyangwe, L. ; Geerts, S. (2001). Standardised tests in mice and cattle for the |
|detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle. Veterinary Parasitology; 97; (2001) 171-182. |
|Issa Sidibé, Zakaria Bengaly, Hamidou Boly, Rafmane Ganaba, Marc Desquesnes and Laya Sawadogo (2002).Differential pathogenicity of Trypanosoma |
|congolense subgroups: Implication for the strategic control of trypanosomosis. Newsletter on Integrated Control of Pathogenic Trypanosomes and their |
|Vectors, N°6, September 2002; p.33-35. |
|Z. Bengaly, I. Sidibé, R. Ganaba, M. Desquesnes, H. Boly, L. Sawadogo (2002).Comparative pathogenicity of three genetically distinct Trypanosoma |
|congolense-types in cattle: clinical observations and haematological changes. Veterinary Parasitology; 108; (2002) 1-19. |
|Augustin Ziro Bancé, Albert Patoin Ouédraogo, Burkhard Bauer, Idrissa Kaboré et Issa Sidibé (2002).Efficacité du Triflumuron Selon la Nature et la |
|Couleur du Tissu à l’égard de Glossina palpalis gambiensis Vanderplank, 1949. Insect Sci. Applic. Vol 22, N° 4, pp 281-287, 2002. |
|Jean Charles Maillard, Isabelle Chantal, David Berthier, Sophie Thevenon, Issa Sidibe, Hanta Razafindraibe.Molecular immunogenetics in susceptibility |
|to bovine dermatophilosis – a candidate gene approach and a concrete field application. Ann N Y Acad Sci. 2002 Oct; 969: 92-6. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |BOUYER |Date of birth: |04/09/1977 |
| | | | | |
| |Forenames: |Jérémy |Nationality: |French |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| |
|In course: PhD student « Characterization of riparian tsetse flies populations in the northern limit of their distribution area » . Université |
|Montpellier II « Sciences et techniques du Languedoc » (2003/2004) |
|Master of Parasitology “Distribution of tsetse flies in the Mouhoun river bassin, Burkina Faso” |
|Université Montpellier II « Sciences et techniques du Languedoc » (2002) |
|Degree of applied animal epidemiology “Epidemiology of Rift Valley Fever in Senegal” Ecole nationale vétérinaire d’Alfort (2002) |
|Certificate of veterinary tropical pathology. “Epidemiological Model for Rift Valley Fever in Senegal” Ecole nationale vétérinaire de Toulouse et |
|Cirad-Emvt (2001) |
|Veterinary thesis. Ecole nationale vétérinaire d’Alfort (2001) |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Researcher in vector ecology |
| | | | | |
| |Department: |UREEN |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |01/01/2002 |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| |CIRAD-Emvt Montpellier France |
| | | | | |
| |
| | | | | |
|(e) |Source of personal salary support |CIRAD-Emvt |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid |- |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
|In course: PhD student, from 2003- |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
|- |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|- |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
|- |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |THEVENON |Date of birth: |29/11/1974 |
| | | | | |
| |Forenames: |Sophie |Nationality: |french |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|Doctor in veterinary medecine, Veterinary school of Alfort, 1997. |
|Master in Ecology, Paris 67 University, 1998 |
|PhD in Ecology, Paris 6 University, 2001 |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |researcher |
| | | | | |
| |Department: |URBIO |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |permanent |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|CIRAD |
| | | | | |
|(e) |Source of personal salary support |French research center |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): |. |
| | | | | |
| |
|CIRAD from 1991 |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
| |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
| |
|Berthier, D., Quéré, R., Thévénon, S., Belemsaga, D., Piquemal, D., Marti, J. & Maillard, J.C., 2003. Serial analysis of gene expression (SAGE) in |
|bovine trypanotolerance : preliminary results. Genetic Selection Evolution., 35, S35-S47. |
|Thévenon, S., Le Thi Thuy, Le Viet Ly, Maudet, F., Bonnet, A., Jarne, P. & Maillard, JC., 2004. Microsatellite analysis of genetic diversity of the |
|Vietnamese sika deer (Cervus nippon pseudaxis). Journal of Heredity. 95(1) : 11-18. |
|Thévenon, S., Bonnet, A., Claro, F. & Maillard, JC., 2003. Genetic diversity analysis for captive propagation : the Vietnamese sika deer (Cervus |
|nippon pseudaxis) in zoological parks. Zoo Biology, 22(5), 465-475. |
|Bonnet-Garnier, A., Claro, F., Thévenon, S., Gautier, M. & Hayes, H., 2003. Identification by R-banding and FISH mapping of chromosome arms involved |
|in robertsonian translocations in several deer species. Chromosome Research, 11(7), 649-663. |
|Thévenon, S. & Couvet, D., 2002. The impact of inbreeding depression on population survival depending on demographic parameters. Animal conservation, |
|5, 53-60 |
|Bonnet, A., Thévenon, S., Maudet, F. & Maillard, JC., 2002. Efficiency of semi-automated fluorescent multiplex PCRs with eleven microsatellite markers|
|for genetic studies of deer populations. Animal Genetics, 33(5), 343-350. |
|Bonnet, A., Thévenon, S., Claro, F., Gautier, M., Eggen, A. & Hayes, H., 2001. Cytogenetic comparison between Vietnamese sika deer and cattle: |
|R-banded karyotypes and FISH mapping. Chromosome Research, 9, 673-87. |
|Thévenon, S., Claro, F., Bonnet, A. & Volobouev, V., 2000. Karyotype identity of two subspecies of Eld’s Deer [Cervus eldi (Cervinae, Artiodactyla)] |
|and its consequences for conservation. The Journal of Heredity, 91, 402-405 |
| |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |KABORE |Date of birth: |01/01/1956 |
| | | | | |
| |Forenames: |Idrissa |Nationality: |Burkinabe |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| Ingenieur d’Elevage (1982) University of Ouagadougou (Institut Supérieur Polytechnique) |
|Maîtrise des sciences et techniques du Développement Rural (1980) |
|Diplôme Universitaire d’Etudes Biologiques (1978) |
| | | | | |
|(c) |Current post Vector control and Tsetse rearing |
| | | | | |
| |Title: |Tsetse Entomologist |
| | | | | |
| |Department: |URBIO |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |2000-permanent |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|Burkina Faso Ministry of Animal ressources |
| | | | | |
|(e) |Source of personal salary support |Government of Burkina Faso |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| Since 1998, Researcher involved in the Bioscience and Integrated diseases control Unit of CIRDES: |
|- Large scale rearing of three Glossina SPP.on an in vitro system. Production of 1 million sterile males |
|for a tsetse eradication campaign in a pastoral zone in Burkina Faso. Research on Automation of |
|tsetse mass rearing techniques and Quality Control. |
|- Bioassays with pyrethroids and other chemical compounds |
|- Entomological and epidemiological surveys |
|- Apply research on Integrated vector control techniques with communal participation. |
|- Training of African scientists, technicians and producers in laboratory and field techniques relevant |
|to integrated tsetse control including the SIT. |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
|Transfer of any achievements to the NARS and Producers through workshops and extension support |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
| |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
|KABORE (I.) (2003) – Some practical aspects of community-based tsetse control. Workshop on epidemiology and control of trypanosomiasis in Ghana, , |
|Pong Tamale, Ghana, 8 – 9 December 2003. |
|BANCE Z.A., OUEDRAOGO P.A., BAUER B., KABORE I., SIDIBE I. (2002) - Efficacité du Triflumuron Selon la Nature et la Couleur du Tissu à l’égard de |
|Glossina palpalis gambiensis Vanderplank, 1949. Insect Sci. Applic. Vol 22, N° 4, pp 281-287, 2002. |
|BAUER B., KABORE I., LEFRANCOIS T., SOLANO P. (2000) – Impact of Triflumuron impregnated targets on two tsetse populations (Glossina morsitans |
|submorsitans Newstead and G. tachinoidesWestwood) in the game ranch of Nazinga, southern Burkina Faso. Acta Tropica |
|BAUER B., AMSLER-DELAFOSSE S., KABORE I., KAMUANGA M.J.B. (1999) – Improvement of cattle productivity through rapid alleviation of african animal |
|trypanosomosis by integrated disease management practices in the agropastoral zone of Yale, Burkina Faso. Trop. Anim. Health and Prod. 31 (1999) 89 -|
|102. |
|KABORE (I.), BAUER (B.) – 20 Years of Autonomous Large-Scale Rearing of 3 Glossina SPP on an in vitro System. Proceeding of the FAO/IAEA |
|International Conference on Area-Wide Control of Insect Pests Integrating the Sterile Insect and Related Nuclear and other Techniques, Penang, |
|Malaysia, 28 May – 2 June 1998. |
|RAYAISSE (J.B.), KABORE (I.), BAUER (B.) – Experiments on reptiles odours in Samorogouan department, Province of Kénédougou, Burkina Faso. Second |
|Research Co-ordination Meeting, Penang, Malaysia, 26 – 31 May 1998. |
|KAMUANGA (M.), KABORE (I.), SWALLOW (B.), AMSLER-DELAFOSSE (S.), BAUER (B.) – Evaluating factors effecting implementation of community- based tsetse |
|control in southern Burkina Faso. Quaterly Journal of international Agriculture, 1996. |
|KABORE (I.), AMSLER-DELAFOSSE (S.) – Rapport d’évaluation du projet FAO, TPC/MLI/4553 « Appui à la lutte contre la mouche tsé-tsé et la trypanosomose |
|animale » Sikasso, Mali, 19 – 29 juillet 1996. 13 pages. |
|KABORE (I.), DELAFOSSE-AMSLER (S.), BAUER (B.) – Lutte contre les mouches tsé-tsé (Glossina spp) et les tiques par application épicutanée de |
|pyréthrinoides sur le bétail dans différentes zones du Burkina Faso : importance de la participation communautaire. VIII conférence internationale des|
|Institutions de Médécine Vétérinaire Tropicale, 25 - 29 septembre 1995, Berlin, RFA. Afrique agriculture n° 231, Novembre 1995. |
|BAUER (B.), AMSLER-DELAFOSSE (S.), CLAUSEN (P.-H.), KABORE (I.), PETRICH-BAUER (J.) – Successful application of deltamethrin « pour on » to cattle in|
|a campaign against tsetse flies (Glossina spp.) in the pastoral zone of Samorogouan, Burkina Faso. Trop. Med. Parasitol., 1995, 46 (3) : 183 – 189. |
Q19 Curriculum vitae of applicant(s)
This and the next page should be duplicated for each Principal, Joint and Coapplicant
|(a) |Surname: |SIBERT |Date of birth: |16-12-1972 |
| | | | | |
| |Forenames: |Alexandre |Nationality: |French |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|PhD in population genetics |
|MSc in genetic epidemiology |
|MSc in engineering at the Ecole Polytechnique |
| | | | | |
|(c) |Current post |
| | | | | |
| |Title: |Researcher scientist |
| | | | | |
| |Department: |EMVT |
| | | | | |
| |Institution: |CIRAD |
| | | | | |
| |Date of appointment and if appropriate, expected termination: |26-08-2002 permanent |
| | | | | |
|(d) |With whom do you have your contract of employment? |
| | | | | |
|CIRAD-EMVT, Montpellier, france |
| | | | | |
|(e) |Source of personal salary support |CIRAD-EMVT |
| |e.g. Research Council, University etc. Please also be specific if salary is | |
| |funded from more than one source. | |
| | | | |
|(f) |Current salary in the currency in which it is paid | |
| |(if salary is being requested from the Trust): | |
| | | | | |
|(g) |Last three posts held (with dates): | |
| | | | | |
| |
|Temporary teaching and research assistant (ATER) in biostatistics, Paris 7 University, 2001-2002 |
| |
|Temporary teaching assistant (Moniteur) in computer sciences, Paris 7 University, 1998-2001 |
|(h) |Research outcomes other than publications |
| |Provide any relevant information in relation to patents, commercialisation, industry involvement, effect on healthcare practice and/or |
| |policy. |
| |
| |
| | |
|(i) |Other professional, academic or related activity |
| |Please outline any other responsibilities and duties that will be undertaken in addition to your role on this grant (e.g. teaching, clinical |
| |practice, industry consultation, administration etc). |
| |
|Collaboration with PhD student on Glossina spp. dispersal models |
|Collaboration with PhD student on Stomoxys spp. popluation modelling |
|Collaboration with Post-Doc student on duplicated microsatellites analysis (publication submitted) |
|Collaboration with PhD student on evolutionary impact of maternal care |
| | | | | |
|(j) |Recent publications (No more than ten, which should be those you consider to be the most important and relevant to this application. Please |
| |give citation in full, including title of paper and all authors. Also quote papers ‘in press’) |
| |
| |
|Sibert A and Balaresque P (submitted) Duplicated Y-chromosome microstellites: does order in haplotypic data matter? |
|Sibert A and Goldgar DE (2003) The effect of disease penetrance, family size, and age of onset on family history with application to setting |
|eligibility criteria for genetic testing. Fam Cancer 2003, 2:35-42 |
|Sibert A, Austerlitz F and Heyer E (2002) Wright-Fisher revisited: the case of fertility correlation. Theoretical Population Biology 62:181-197 |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: | Mweempwa |Date of birth: |10 December 1962 |
| | | | | |
| |Forenames: |Cornelius |Nationality: |Zambian |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|BSc in Chemistry and Biology, 1983-1987, University of Zambia |
|MSc in Tsetse and Trypanosomiasis Control, 1997-1999, University of Zimbabwe |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Principal Biologist |
| | | | | |
| |Institution: |Department of Veterinary and Livestock Development, Zambia |
| | | | | |
| |Funding body: |Zambian Government |
| | | | | |
| |Termination date of support: | |
| | | | | |
| |Current basic salary and incremental date: |€ 513.5 |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: | |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
|Principal Tsetse Biologist, Department of Veterinary and Livestock Development, Zambia (1997- to date) |
|Senior Tsetse Biologist, Department of Veterinary and Livestock Development, Zambia (1992-1997) |
|Tsetse Biologist, Department of Veterinary and Livestock Development, Zambia (1988-1992). |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
|Lumamba, D., Mweempwa, C., Mubanga, J. and Leroy, E. (1997) Eradication of Glossina morsitans morsitans and Glossina pallidipes in the Kariba |
|Hills of Siavonga, southern Zambia. Proceedings of the 24th meeting of the International Council for Trypanosomiasis Research and Control |
|(ISCTRC), Maputo, pp 427-431. |
|Chamisa, A. and Mweempwa, C. (1997) Control of tsetse flies Glossina pallidipes Austen and Glossina morsitans morsitans Westwood in the Kariba |
|Hills, an area common to Zambia and Zimbabwe. Proceedings of the 24th meeting of the International Council for Trypanosomiasis Research and |
|Control (ISCTRC), Maputo, pp 432-437. |
|Mweempwa, C. (1999) Responses of tsetse flies (Diptera: Glossinidae) to odours of animal excretions. MSc Thesis, University of Zimbabwe, |
|Department of Paraclinical Veterinary Studies, 55pp. |
| |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: |YONI |Date of birth: |7/12/1967 |
| | | | | |
| |Forenames: |A.J. Wilfrid |Nationality: |Burkinabê |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| Bachelor of Science 1992 University of Ouagadougou (Burkina Faso) |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Technician |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Funding body: |CIRDES (EU Project’s Procordel) |
| | | | | |
| |Termination date of support: |31/03/2005 |
| | | | | |
| |Current basic salary and incremental date: |350 Euro |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: |- |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
| |
|Field and laboratory technician (entomology, data management and SIG) in CIRDES |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
|- |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: |Sanogo |Date of birth: |12/02/1965 |
| | | | | |
| |Forenames: |Lansina |Nationality: |Burkinabe |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|Bachelor of Science (Economics) 1986 University of Ouagadougou (Burkina Faso) |
|2nd year of University (DEUG II), 1988 |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Technician |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Funding body: |CIRDES (EU Project’s Procordel) |
| | | | | |
| |Termination date of support: |31/03/2005 |
| | | | | |
| |Current basic salary and incremental date: |350 Euros |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: |- |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
| |
|Field technician (socioeconomics), Cirdes |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
|- |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: |Bila |Date of birth: |02 /01/1969 |
| | | | | |
| |Forenames: |Céné |Nationality: |Burkinabe |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| |
|Bachelor of Science, 1992, University of Ouagadougou |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Technician |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Funding body: |CIRDES (EU Project’s Procordel) |
| | | | | |
| |Termination date of support: |31/05/2005 |
| | | | | |
| |Current basic salary and incremental date: |350 Euros |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: |- |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
| |
|Field and Laboratory technician (Parasitology), Cirdes |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
| |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: |Koné |Date of birth: |01/01/1970 |
| | | | | |
| |Forenames: |Siaka |Nationality: |Burkinabe |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
| |
|Terminal degree of High School, Bobo-Dioulasso, Burkina Faso, 1993 |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Driver |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Funding body: |CIRDES (different projects) |
| | | | | |
| |Termination date of support: |temporary |
| | | | | |
| |Current basic salary and incremental date: |300 Euros |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: | |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
| |
|driver, Cirdes, |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
| |
Q20 Curriculum vitae of named research assistant(s)/technician(s)
This page may be duplicated for each named research assistant/technician required.
|(a) |Surname: |Guerrini |Date of birth: |19/11/1972 |
| | | | | |
| |Forenames: |Laure |Nationality: |French |
| | | | | |
|(b) |Degrees, diplomas etc. (subject, class, university and dates): |
| | | | | |
|Master, University of Montpellier |
| | | | | |
|(c) |Current post (if not currently in employment, please give details of most recent post): |
| | | | | |
| |Position and grade: |Assistant in Geographic Information System |
| | | | | |
| |Institution: |CIRDES |
| | | | | |
| |Funding body: |CIRAD/France |
| | | | | |
| |Termination date of support: |permanent |
| | | | | |
| |Current basic salary and incremental date: | |
| | | | | |
| |Basic salary must be shown separately from any salary enhancements or other allowances. |
| | | | | |
| |If currently funded by a Wellcome Trust grant, please give grant reference number: | |
| | | | | |
|(d) |Last three posts held (with dates): |
| | | | | |
| |
|Assistant in Geographic Information System in Cirad, Montpellier |
| | | | | |
|(e) |Recent publications (No more than ten. Please give citation in full, including title of paper and all authors. Also quote papers ‘in |
| |press’) |
| | | | | |
| |
Q21 Reasons for support requested: General
Please justify (a) period of the project; (b) staff requested; (c) materials and consumables; (d) training costs; and (e) miscellaneous costs.
a) Period of the project
The following costs are in Euros
A total duration of three years has been proposed.
Activities are divided as follow:
Year 1: Start of project, development of detailed workplans, purchase of equipment, basic training of field staff and collection of baseline data”.
Historical analysis of the evolution of the habitat over time (about 10 years) using remotely sensed data and collection of baseline data (vegetation, climate etc…) of the study area. The analysis of current degree of habitat fragmentation using remotely sensed data will be conducted and the level of habitat fragmentation in the study area will be quantified and qualified. The distribution and density of tsetse in the study area will be determined through intensive tsetse surveys in habitat fragments and the relationship between fragmentation type and tsetse presence or absence will be studied. At the end of the first year, representative habitat fragments (referred to as “study sites”) for the longitudinal study of the tsetse population and disease transmission dynamics (to be conducted in year 2) will be identified and training of field staff involved in the project will start.
Year 2: Longitudinal study of tsetse and cattle (surveillance period).
Tsetse monitoring sites will be established in the selected study sites (see above). The tsetse population will be monitored (e.g. tsetse apparent density, age determination, size, infection rate and host preference) during the whole of the second year. This will allow the inclusion of all seasons. Concurrently tsetse samples will be collected from the study sites for genetic comparison. Tsetse samples collected during the surveillance period will be analysed and the monthly; age distribution (ovarian ageing and mean wing fray value), size of male and female flies (mean wing vein length), infection rate and trypanosome species prevalence will be determined. Concurrently, sentinel cattle herds will be established near selected study sites. Sentinel animals will be sampled monthly to determine incidence and trypanosome species prevalence of trypanosome infections. The monthly distribution and movement patterns of the sentinel cattle will be monitored. Also during year two cattle census data will be collected and information will be collected on disease management practices. All field data will be entered into a database.
Year 3: Analysis, modelling and reporting.
The analyses of samples collected in the field will be finalised in the first part of year 3. The information collected in year 2 will be analysed and the relationship between the level of habitat fragmentation, tsetse population fitness and disease transmission will be established.
b) Staff requested
Salary of 1 Post-doctorant RA grade 1RA (€ 35 000) in Oxford University for models in population dynamics and R0
Salary of 1 PhD in Burkina Faso and Zambia (€ 24 000 each)
Salary of 2 casual field technicians (socio-economic surveys…) in Burkina Faso and Zambia (€ 8 000)
Salary of one entomological/parasitological technician in Burkina Faso and Zambia (€ 15 000 each)
Salary of one driver in Burkina Faso and Zambia (10 000 Euros each)
c) Materials and consumables:
- Material for tsetse storage and shipment: this provision includes storage tubes and bags for storage and preservation of tsetse flies sampled in the field and further DNA analyses in specialist laboratories.
- Consumables for parasitological diagnosis of trypanosomiasis (sentinel herds): A provision has been made for the purchase of cover slips, filter papers, slides, slide boxes, staining material, capillary tubes, vacutainer tubes, eartags and needles for the monthly sampling of the sentinel herds during year 2 (500 animal, 10 sentinel herds, € 4000 Euros in Burkina Faso and Zambia).
- Veterinary drugs: A total of 400 sachets of diminazene aceturate (2.36g) will be purchased for treatment of the parasitologically positive sentinel animals. Antibiotics and anthelmintics will be purchased for treatment of sentinel animals when required (€ 1000 per sites).
- PCR-analyses: A provision has been made for the consumables needed for PCR analysis of a total of i) about 1000 samples at the molecular laboratories of the veterinary department of the Institute of Tropical Medicine (Antwerp, Belgium) and the Department of Veterinary Tropical Diseases of the Faculty of Veterinary Science (Pretoria, South Africa) for Zambia study, ii) about 1200 blood samples from infected cattle or tsetse flies at the molecular laboratories of CIRDES. In addition, PCR for the identification of trypanosome species: € 3500 per sites with a predicted incidence of 15 % in animals and 10 % in tsetse flies.
- genetic of flies: The number of samples for genetic flows analyses of 5 tsetse populations per involved species is of 300 (30 individuals by population and 10 loci). € 7000 per sites, including preliminary experiments.
- Production of tsetse fly for dispersal assessment and modelling (20 000 flies) € 2000.
- Odours for tsetse traps: about 400 l. of acetone will be purchased for the baiting of the 50 tsetse traps during the tsetse surveys and tsetse monitoring.
- Bloodmeal identification: A provision is made for the shipment of tsetse samples for bloodmeal identification (i.e. host identification). A total of about 500 samples per site will be analysed.
- Vehicle running costs: include the running costs of a four-wheel-drive vehicle provided by the Zambian Veterinary Department and Cirdes for transport from the headquarters of the tsetse unit respectively (Lusaka and Bobo Dioulasso) to the study area (Katete, Mouhoun River bassin). Provision has been made for a total of 22 trips in Zambia (5 in year 1, 12 in year 2 and 5 in year 3) and 70 trips in Burkina (5 in year 1, 60 in year 2 and 5 in year 3). The distance to and from the project area totals 1500km and 250 km. Vehicle running costs are calculated at € 0.25 per km in Zambia, € 0,46 in Burkina. Total Cost: € 8250 and € 8000 in Burkina Faso
Renovation field laboratory: A provision is made for the purchase of material to renovate the field laboratory in the study area of Zambia (Katete District). The field laboratory is essential for sample storage, tsetse dissections, sample examination etc… A small field lab has been functional in the study site until 1998. It needs the necessary renovations to upgrade the facilities. A lump sum to purchase materials for renovating the facilities has been allocated for this purpose.
d) Training costs
- PhD scholarship of the Zambia Scientist: Training costs include a three year PhD scholarship for the Zambian scientist. He will be registered at the Department of Veterinary Tropical Diseases (DVTD) of Faculty of Veterinary Sciences of the University of Pretoria and be supervised by Dr P Van den Bossche (Joint Applicant) who has an appointment as Extraordinary Professor at the Department of Veterinary Tropical Diseases. Provision has been made for the registration fee (1x) and annual re-registration fees (x2): € 1700.
- PhD scholarship of the Burkinabe Scientist: Training costs include a three year PhD scholarship. He will be registered at the University of Ouagadougou and be supervised by Dr. Issa Sidibé, head of biological and integrated disease control (URBIO/CIRDES) and Pr. Kabré Gustave (University of Ouagadougou). Provision has been made for the registration fee (1x) and annual re-registration fees (x2): € 250.
- Edition of document: Provision is made for the production of intermediary reports and thesis (€ 600 Euros).
e) Miscellaneous costs
Visit of Zambian scientist to DVTD (Pretoria, South Africa): Provision is made for the air tickets for annual visits by the Zambian PhD student to the University of Pretoria. Subsistence costs (Trust scale) for a total of 24 days over the three years (7 days in year 1, 7 days in year 2 and 10 days in year 3) are also included. During his visits to the DVTD he will discuss progress made with the implementation of the workprogramme, will be trained in the use of molecular tools for the diagnosis trypanosomiasis and will receive assistance with the statistical analysis and interpretation of the data. € 3990.
- Visit of burkinabe scientist to IRD/CIRAD Laboratory, Montpellier, France): Provision is made for air tickets, subsistence costs (Trust scale) for two visits, 24 days for training in the use of molecular tools for tsetse population genetics, statistics and data analysis. € 5200.
Scientific exchange visits: The provision made under this item covers the price of air tickets and subsistence costs for field visits by European collaborators and visits by the Zambian/Burkinabee scientist to the institutes of the European collaborators.
- Joint Applicant 1 to Zambia: Provision has been made for 1 visit every year for a duration of 10 days each: € 19 000
- Principal Applicant to Burkina: Provision has been made for 1 visit every year for a duration of 10 days each: € 19 000
Field allowances: Field allowances will be paid for the scientist and technical staff attached to the programme.
- The allowances will be paid in accordance with the Zambian Government rates. The Zambian scientist will receive € 31/night for a total of 10 days per month (6 months in year 1, 12 months in year 2 and 6 months in year 3). Field staff will receive an allowance of € 58/month (6 months in year 1, 12 months in year 2 and 6 months in year 3).
- In Burkina Faso, the rate is about € 15,3 per day total cost € 7500.
fuel, oil for the portable generator. A provision has also been made for the purchase of fuel, oil and cost of normal maintenance of the portable generator used in the field laboratory. It is estimated that the generator will be used for a total of about 900 hours. Estimated cost (running and maintenance cost) are € 0.3 per hour € 270 per year, during 2 years.
Office running costs: This item will cover the costs of running a small office for data management and reporting. Costs include paper, ink for printer cartridges, telephone costs (international calls), mailing, etc…
Shipment of samples from Burkina Faso and Zambia to the specialised laboratory (€ 400)
Collaborator: Guy Hendrickx (Avia-GIS) is proposed as collaborator for its experience in the topics. He will be in charge of Remote Sensing data acquisition and pre-processing for the whole of the project, Land-use / land-cover change analysis, identification of landscape fragmentation for the Zambian part
Coordination: specific budget is requested for coordination activities for the Principal Applicant and Joint applicant. This budgets will be used for editing, telephone costs (international calls), mailing… and also include contingency funds and editing budgets for the final reports. € 6000 per years.
Q21 Reasons for support requested: Equipment
Please justify (f) equipment, equipment maintenance and access charges.
For access charges, please show how they have been calculated on a cost recovery basis. This can include
(i) a maintenance or service contract providing a basic level of service, (ii) running costs, (iii) materials and consumables and (iv) staff time. Please also state the percentage of time/number of hours the equipment/facility will be used for the project.
General laboratory equipment
Camping tables and chairs will be used during field work (sampling of sentinel herds) and in the field laboratory (€ 1000)
Global positioning system: Global Positioning Systems will be purchased. They will be used in ground thruting of the remotely sensed information, for determining the georeferences of the tsetse traps and to determine movement patterns of cattle herds in the study area. 3 for Zambia (€ 1200), 2 for Burkina Faso (€ 800)
Tsetse dissecting set: entomological sets (entomological needles and forceps) will be purchased for tsetse dissections. 5 in Zambia (€ 250), 2 for Burkina (€ 100)
Coolboxes and ice packs: coolboxes and sufficient icepacks will be purchased for sample storage and sample transportation. 4 in Zambia (€ 480), 2 in Burkina (€ 240)
Gas fridge/freezer: In Zambia, one gas fridge/freezer will be purchased to store field samples (tsetse flies, serum, blood spots of filter paper) for later analysis. Provision is also made for the running costs i.e. gas of the fridge/freezer. € 1500.
Electric freezer: Further provision is made for an electric freezer for long-term storage of samples for each sites. € 1500 for all.
Portable generator: A portable generator will be purchased for each site for use during parasitological field surveys and during the laboratory field work (e.g. dissections of tsetse flies to determine infection rates). € 800 for each.
Microscopes
Micrometer ocular: One micrometer ocular will be purchased for measuring the length of the wing vein to determine the size of the tsetse flies. € 170
2 microscopes (one for each sites) will be purchased for the parasitological diagnosis of trypanosome infections in livestock and tsetse flies. € 9000
2 binoculars for tsetse dissection will be purchased (€ 5000).
Centrifuges
Microhaematocrit centrifuge: a microhaematocrit centrifuge will be used for the parasitological diagnosis of trypanosome infections in livestock (monitoring of sentinel herds). (€ 3850 each).
Computing and imaging
1 laptop computer and accessories (printer, modulator, etc.) will be purchased for and be used by the Zambian and burkinabee scientists for data storage and analysis (€ 3000 each).
In addition, one powerfull desk computer will be requested in Bukina Faso for satellite image analysis (€ 2000).
software
- Current software for desktop and laptop (Norton antivirus, Office, etc.) (€ 3 000 for each).
- Free software will be used to achieve population genetics analysis.
- Meta X Software: Meta X software will be used to conduct metapopulation viability analyses on the Zambian data (€ 3000).
- BorlandR C++: In case META-X does not provide all the answers, the C++ programming environment can be used to develop additional models. The C++ programming environment provides a the freedom to implement any expert rule. This allows to test specific rules about the dynamic process that results from the META-X output.
- For GIS analysis, Arcview 8.0 Software and complementary packages will be purchased (€ 2000 Euros).
- For satellite images analysis, ENVI Software licence will be purchased (€ 5000).
Field survey equipment
- Tsetse traps: Confection of 50 Challier-Laveissière biconic traps (for riverine flies) in CIRDES for use in tsetse surveys and monitoring. (€ 1200); Confection of 50 Epsilon traps, Bonar Industries, Harare, Zimbabwe for Savannah flies) will be used in the survey and the tsetse monitoring (€ 3000). The total cost includes transport of traps from Harare to Lusaka.
Flyround equipment: Equipment (black cloth and mosquito netting) will be purchased to conduct man-walked flyrounds in Zambia. € 150
Motorbikes: Two motorbikes will be purchased to ensure the mobility of the field scientist and his assistants in the study sites. A provision is also made for motorbike running costs for a total of 28 months (12 months year 1, 12 months year 2 and 4 months year 3) for each motorbike. It is estimated that each motorbike will drive 250 km per month during the 2 first years, and 6 month during the last year. Running costs are estimated at € 0.15 per km. total cost: € 5000
Bicycles: IN each site, five bicycles will be purchased for use by the technical assistants in the study site. This provision also includes the purchase of spare parts for the bicycles. Each bicycle is evaluated at € 100.
Protective clothing: A total of 15 sets of protective clothing (boots, overall) will be purchased for all field staff (€ 400)
Q21 Reasons for support requested: Animals
Please justify (g) animals.
i) Why is animal use necessary: are there any other possible approaches?
ii) Is the species to be used the most appropriate? This is especially important when an animal is being used as a model for a human physiological or pathological condition.
iii) The experimental design should include the case for the number of animals required to achieve significance and the factors that might affect this. The sample size calculations used to estimate the number of animals required in the proposed experimental design should be stated where appropriate.
/
COSTINGS
Currency used: Office use only Exchange rate:
Q22 Requests for animal costs
|(a) Animal species | |
| | |
|Indicate species of animal used: | |
| |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |
|(b) Purchase | | | | | |
| | | | | | |
|Number to be purchased per annum | | | | | |
|Source of supply and biological quality | |
|Purchase price per animal | |
| |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |
|(c) Maintenance | | | | | |
| | | | | | |
|Number of animals to be maintained | | | | | |
|Number of weeks’ maintenance required | | | | | |
|Cost per animal per week | |
|(d) Experimental procedures | |
| | |
|Types of procedure | |
| | |
| | |
|Cost per procedure(s) | |
| | |
Q23 Financial details of support requested: salaries
(a) General salaries (include studentships, other training posts, technicians etc.) Space for 5 posts is shown, but these fields can be copied and pasted into the document if more are required – please number the posts accordingly.
(see page 47 for Additional Information on research allowances for individuals from developing countries).
|POST 1 | | | | | | |
|Name: | Post-doc RA 1 |Post/Grade: |Point 3 start |Incremental date: |01/01/06 |
| | | | | | | |
|Start Date: 01/01/06 |End Date: |31/06/07 | |Time spent on grant (%): |100 |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: | |41665 |23431 | | |€ 65096 |
|Employer’s contributions: | |7453 |3933 | | |€ 11386 |
|15 % | | | | | | |
|Sub total | |€ 49118 |€ 27364 | | |€ 76482 |
| | | | | | | |
|POST 2 | | | | | | |
|Name: |PhD (Burkina Faso) |Post/Grade: |MSc |Incremental date: | |
| | | | | | | |
|Start date: 01/01/05 |End date: |31/12/07 | |Time spent on grant (%): |100 |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: |5840 |5840 |5840 | | |17520 |
|Employer’s contributions: |2160 |2160 |2160 | | |6480 |
|26 % | | | | | | |
|Sub total |8000 |8000 |8000 | | |€ 24000 |
| | | | | | | |
|POST 3 | | | | | | |
|Name: |Technician |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: 01/01/05 |End date: |31/12/07 | |Time spent on grant (%): |100 |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: |3900 |3900 |3900 | | |11700 |
|Employer’s contributions: |1100 |1100 |1100 | | |3300 |
|26 % | | | | | | |
|Sub total |5000 |5000 |5000 | | |€ 15000 |
|POST 4 | | | | | | |
|Name: |Technician |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: 01/01/05 |End date: |31/12/07 | |Time spent on grant (%): |25 |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: |3900 |3900 |3900 | | |11700 |
|Employer’s contributions: |1100 |1100 |1100 | | |3300 |
|26 % | | | | | | |
|Sub total |5000 |5000 |5000 | | |€ 15000 |
|POST 5 | | | | | | |
|Name: |01/01/05 |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: 01/01/05 |End date: |31/12/07 | |Time spent on grant (%): |100 |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: |2442 |2442 |2442 | | |7326 |
|Employer’s contributions: |858 |858 |858 | | |2574 |
|26 % | | | | | | |
|Sub total |3300 |3300 |3300 | | |9900 |
|(b) Principal investigators or coapplicants seeking their own salary |
|Space for 3 posts is shown, but these fields can be copied and pasted into the document if more are required – please number the posts accordingly. |
|POST 6 |
|Name: | |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: |End date: | | |Time spent on grant (%): | |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: | | | | | | |
|Employer’s contributions: | | | | | | |
| % | | | | | | |
|Sub total | | | | | | |
| | | | | | | |
|POST 7 | | | | | | |
|Name: | |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: |End date: | | |Time spent on grant (%): | |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: | | | | | | |
|Employer’s contributions: | | | | | | |
| % | | | | | | |
|Sub total | | | | | | |
| | | | | | | |
|POST 8 | | | | | | |
|Name: | |Post/Grade: | |Incremental date: | |
| | | | | | | |
|Start date: |End date: | | |Time spent on grant (%): | |
| | | | | | | |
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|Commencing salary: | | | | | | |
|Employer’s contributions: | | | | | | |
| % | | | | | | |
|Sub total | | | | | | |
Q24 Financial details of support requested: Other costs
Research expenses (no ‘inflation’ allowable for years 2–5)
| | |Year 1 |Year 2 |Year 3 |Year 4 |Year 5 |Total |
|(a) Materials and consumables | | | | | | |
|(Please give brief description) | | | | | | |
|Tsetse storage and shipment |500 |500 |100 | | |1100 |
|Cons. parasitological diagnosis |3100 |3000 |- | | |6100 |
|Veterinary drugs |850 |700 |- | | |1550 |
|PCR analyses/trypanosomes |2500 |3000 |1500 | | |7000 |
|PCR analyses/tsetse |2500 |8000 |3500 | | |14000 |
|Odours for tsetse traps |800 |- |- | | |800 |
|Bloodmeal identification |1000 |3500 |500 | | |5000 |
|Vehicle running costs |2925 |11500 |2875 | | |17300 |
|Renovation field laboratory |1500 |- |- | | |1500 |
|Production o tsetse flies |- |1620 |- | | |1620 |
|Fuel and oil |350 |350 |300 | | |1000 |
|Satellite images |20000 |- |- | | |20000 |
|Consommable modelling lab |4000 |5000 |6000 | | |15000 |
|Contribution to ERDAS site licence |3067 | | | | |3067 |
| |966 | | | | |966 |
|IDRISI, 1 licence plus upgrades |805 | | | | |805 |
| |161 | | | | |161 |
|Contribution ESRI/ARC site licence |500 | | | | |500 |
| | | | | | | |
|Mapinfo, 1 licence plus upgrades | | | | | | |
|IDRISI Kilimandjaro licence | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
| | | | | | | |
|(b) Training costs | | | | | | |
|(Please give brief description) | | | | | | |
| | | | | | | |
|PhD scholarship Zambia |1500 |100 |100 | | |1700 |
|PhD scholarship Burkina Faso |100 |75 |75 | | |250 |
|Editions |150 |150 |300 | | |600 |
|(c) Miscellaneous costs | | | | | | |
| | | | | | | |
|Visit of Zambian scientist to DVTD |1240 |1240 |1510 | | |3990 |
|Visit of Burk. scientist to CIRAD |- |2600 |2600 | | |5200 |
|Scientific exchange visit Joint Ap.1 |6300 |6300 |6400 | | |19000 |
|Scientific exchange visits Princ. Ap |6300 |6300 |6400 | | |19000 |
|Scientific expertise visite Joint Ap 2 |5000 |- |5000 | | |10000 |
|Field allowances Africa |3700 |9500 |3200 | | |16400 |
|Office running costs Africa |1500 |1500 |1500 | | |4500 |
|Shipment of sample |200 |400 |200 | | |800 |
|Coordination costs (incl. contingency and |6000 |6000 |6000 | | |18000 |
|final reports) | | | | | | |
|Collaborator (RS pre-processing & |30000 |20000 |17000 | | |67000 |
|Landuse/landcover change in Zambia) | | | | | | |
|Subtotal |107514 |91335 |65060 | | |€ 263909 |
|Q25a |Financial details of support requested: Equipment (This page may be duplicated if necessary) |
| |Please provide contact details for the university’s Director of Procurement/Head of Purchasing (or equivalent). |
|Name: | |Tel: |(32) 3-2476396 |
| | | | | |
|Address: |IMT, Vet depart., Nationalestaat 155, 2000 Antwerpen, BE |Fax: |(32) 3-2476268 |
| | | | |
| | |E-mail: | |
|Type of equipment |Equipment specification |Preferred manufacturer/ Supplier |Duration and total cost of maintenance |Number of items|Cost per item |Total cost |
|(see notes) | |(if known) |contract to be purchased | | | |
|General lab. Equip. |Camping tables and chairs |- |- |- | |750 |
|General lab. Equip. |Global Positioning System |GEKO |- |3 |400 |1200 |
|General lab. Equip. |Tsetse dissecting set |Wironit |- |5 |50 |250 |
|General lab. Equip. |Coolboxes and ice packs |Coleman |- |4 |120 |480 |
|General lab. Equip. |Solar fridge/freezer |- |- |1 |1500 |1500 |
|General lab. Equip. |Electric freezer |- |- |2 |1000 |2000 |
|General lab. Equip. |Portable generator |- |- |1 |1770 |1770 |
|Microscopes |Micrometer ocular | |- |1 |170 |170 |
|Microscopes |Microscope |- |- |1 |4000 |4000 |
|Microscopes |Dissecting microscope |- |- |1 |2500 |2500 |
|Centrifuges |Microhaematocrit centrifuge |Hettich |- |1 |300 |300 |
|Computing and imaging |Laptop computer and software |- |- |1 |4000 |4000 |
|Computing and imaging |Colour printer |- |- |1 |500 |500 |
|Tsetse traps |Epsilon tsetse traps |Bonar Industries, Harare |- |50 |100 |5000 |
|Flyround equipment |Black cloth/mosquito netting |- |- |- | |150 |
|Motorbikes |Motorbike and running costs |To be purchased in Zambia |- |2 |4100 |8200 |
|Bicycles |Produced in Zambia + spare parts |- |- |6 |200 |1200 |
|Protective clothing |Overall and boots |Local Zambian |- |10 |25 |250 |
| | | | | | | |
| | | | | |Total: |€ 34220 |
| | | |Contribution from other sources: | |
| | | | |Amount requested: |€ 34220 |
|Signature: | |Name (in full): | | | | |
| |(University Head of Procurement) | | | | | |
|Q25a |Financial details of support requested: Equipment (This page may be duplicated if necessary) |
| |Please provide contact details for the university’s Director of Procurement/Head of Purchasing (or equivalent). |
|Name: |A. Gouro |Tel: |(226) 97 26 76 |
| | | | | |
|Address: |CIRDES |Fax: |(226) 20 97 23 20 |
| | | | |
| | |E-mail: |gouro@fasonet.bf |
|Type of equipment |Equipment specification |Preferred manufacturer/ Supplier |Duration and total cost of maintenance |Number of items|Cost per item |Total cost |
|(see notes) | |(if known) |contract to be purchased | | | |
|General lab. Equip. |Camping tables and chairs |- |- |- | |250 |
|General lab. Equip. |Global Positioning System |Garmin |- |2 |200 |400 |
|General lab. Equip. |Tsetse dissecting set |Wironit |- |2 |125 |250 |
|General lab. Equip. |Coolboxes and ice packs |Coleman |- |2 |120 |240 |
|General lab. Equip. |Electric freezer |- |- |1 |700 |700 |
|General lab. Equip. |Portable generator |- |- |1 |800 |800 |
|Microscopes |Microscope |- |- |1 |4600 |4600 |
|Microscopes |Dissecting microscope |- |- |1 |2300 |2300 |
|Centrifuges |Microhaematocrit centrifuge |- |- |1 |3850 |3850 |
|Computing and imaging |Desktop computer |- |- |2 |3000 |6000 |
|Computing and imaging |Laptop computer |- |- |1 |2000 |2000 |
|Computing and imaging |General software |- |- |3 |1000 |3000 |
|Computing and imaging |ENVI Software |- |- |1 |5000 |5000 |
|Computing and imaging |GIS Software |- |- |1 |2000 |2000 |
|Traps |Biconic |Local manufacturing |- |120 |10 |1200 |
|Bicycles |Local market |- |- |4 |120 |500 |
|Protective clothes |Local market |- |- |10 |25 |250 |
| | | | | | | |
| | | | | | | |
| | | | | |Total: |€ 33240 |
| | | |Contribution from other sources: | |
| | | | |Amount requested: |€ 33240 |
|Signature: | |Name (in full): | | | | |
| |(University Head of Procurement) | | | | | |
|Q25a |Financial details of support requested: Equipment (This page may be duplicated if necessary) |
| |Please provide contact details for the university’s Director of Procurement/Head of Purchasing (or equivalent). |
|Name: |Mr RN Atkins |Tel: |01865 280480 |
| | | | | |
|Address: |University Offices |Fax: |01865 270708 |
| | | | |
| |Wellington Square |E-mail: | |
|Type of equipment |Equipment specification |Preferred manufacturer/ Supplier |Duration and total cost of maintenance |Number of items|Cost per item |Total cost |
|(see notes) | |(if known) |contract to be purchased | | | |
|1 desktop computer |4Mbyte RAM, 200 Gbyte HDD |Dell |None |1 |5411 |5411 |
| |RAID 5 level rack server unit | | | | | |
|Contribution to multi-terabyte storage| |Transtec Corporation |None |1 |9660 |9660 |
|unit on existing server. | | | | | | |
| | | | | | | |
| | | | | |Total: |€ 15071 |
| | | |Contribution from other sources: |None |
| | | | |Amount requested: |€ 15071 |
|Signature: | |Name (in full): | | | | |
| |(University Head of Procurement) | | | | | |
|Q 25 |Financial Details of Support Requested: Equipment |
| | |
|(b) |Request for Equipment Maintenance and Access Charges for Existing Trust Funded Equipment |
| |
|Maintenance of Existing Trust funded Equipment |
|The Trust will only consider providing maintenance funds for equipment more than five years old if the applicant can demonstrate it is cost-effective to do so (see notes). |
| |
|Details of equipment/facility |Provide Trust grant ref. number and start/end |Date of purchase |Start/end dates of any current maintenance|% of time/hours of use for|Maintenance cost requested based on|
| |dates of original award | |contract, length & total cost |this project |time used for this project |
| | | | | | |
| | | | | | |
| | | | | | |
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| | |
|Access charges |
|Details of equipment/facility |Original source of funding (provide Trust grant reference |Standard access charge per |% of time/hours of use for this |Access charge requested based on time |
| |number if applicable) |hour/day |project |used for this project |
| | | | | |
| | | | | |
| | | | | |
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| | | | | |
Additional information for research allowances
Applicants from developing countries may be eligible for a research allowance. These are small sums of money that can be allocated to such grants to ensure that research workers in developing/restructuring countries, whose salaries are inadequate to maintain a reasonable standard of living, are able to focus full-time on their research work without having to supplement their income from additional private employment. All applicants will be considered on a case-by-case basis and there is no guarantee that such support will be forthcoming. To be considered for a research allowance, each individual must complete the additional information requested on this form.
This page can be duplicated, if necessary.
Section A: Please complete using local currency, stating the currency here:
|Name: | |
| | | |
|Basic annual salary from the employing institution:| | |% of your time that you intend to spend on | |
| | | |the proposed grant: | |
|Other benefits received |Response | |Approximate value and/or nature of benefit |
|Housing (or housing allowance) |YES | |NO | | | |
| | | | |
|Low interest loans from employer, |YES | |NO | | | |
|e.g. for housing or vehicles | | | | | | |
| | | | | | | |
| | | | |
|Medical insurance/free medical treatment |YES | |NO | | | |
| | | | | | | |
| | | | |
|Pension contributions |YES | |NO | | | |
| | | | |
|Salary supplements from external sources. Indicate |YES | |NO | | | |
|period of this support | | | | | | |
| | | | | | | |
| | | | |
|Other (please specify below) | | | |
| |YES | |NO | | | |
| | | | | | | |
|Signature of Head of the Employing Institute: | |Date: | |
|Signature of Applicant: | |Date: | |
Section B: Additional work undertaken
Please note that the information provided in this section is for Wellcome Trust internal purposes only and you do not need to show it to your home institute.
The information given will remain confidential to the Trust.
|Do you currently undertake any additional paid work outside of your home institution’s requirements? |YES | |NO | |
| | | | | |
| |
|How many hours a week does this take up? | Hrs/week |
| | |
|What are your approximate annual earnings from this activity? | |
1. Systems and processes
Choose one primary (compulsory) and up to three secondary (optional).
|Infection |
| |
| |
2. Disease
Choose one primary (compulsory) and up to three secondary (optional).
|African trypanosomiasis |
| |
| |
3. Discipline
Choose one primary (compulsory) and up to three secondary (optional).
|Epidemiology – Entomology – Genetics- Mathematical biology |
| |
| |
4. Technique
Choose up to three (optional).
| |
| |
| |
| |
| |
5. Other identifier
Choose up to six (optional).
| |
| |
| |
| |
| |
6. Mark relevant box (compulsory).
|BASIC | | |
| | | |
|CLINICAL | | |
| | | |
|TROPICAL | |X |
| | | |
|VETERINARY | | |
[pic]
Registered charity no.210183. 183 Euston Rd, London, NW1 2BE. Tel: +44 (0)20 7611 8888 Fax: +44 (0)20 7611 8545 wellcome.ac.uk
Collaboration on a grant
Collaborators, i.e. scientific/medical colleagues, who are associated with a research proposal and named in the body of the application, but are not coapplicants, are asked to complete this form.
|Name of grant applicant: |Stéphane de La Rocque |
| | |
|Department and institution: |CIRAD-EMVT |
| | |
| | |
| | |
| | |
|Name of collaborator: |Guy HENDRICKX |
| | |
|Full address: |Avia-GIS bvba |
| |Agro-veterinary Information and Analysis |
| |Risschotlei 24 |
| |B-2980 |
| |Belgium |
| | |
| | |
| | |
| | |
|Title of research project: |Environmental changes in Africa and tsetse habitat fragmentation: epidemiological consequences and |
| |perspectives for control. |
| | |
| | |
| | |
| | |
|Extent and nature of collaboration: |Remote Sensing data acquisition and pre-processing (a). |
| |Land-use / land-cover change analysis (b). |
| |Identification of landscape fragmentation (b). |
| |Link tsetse population dynamics to LU/LC change and habitat fragmentation (b). |
| | |
| |entire project |
| |Zambia component |
| | |
| | |
| | |
I confirm that I am willing to collaborate as stated above with Dr de La Rocque on this research project
|Signed: |Guy HENDRICKX |Date: |08/07/2004 |
(if more than one copy of this page is required, duplicate as necessary)
Potential Referees
When your completed application is received by the Trust, it will be sent to referees chosen by our scientific staff. To assist us in this process, we ask you to provide the name, full postal address and email/fax/telephone number (if known) of scientific referees whom you feel would be suitable to comment on your application. These should not include colleagues from your institution or those with whom you have collaborated in the last five years, e.g. Coapplicants or co-authors on grants or papers. Please note the following:
• the Trust may or may not choose to approach some, or all, of the individuals you have selected;
• under no circumstances, should you enter into correspondence with them about your application.
Dr Stephen Torr
Natural Resources Institute,
University of Greenwich, Central Avenue,
Chatham Maritime, Kent, ME4 4TB, UK
Tel. +44 (0)1634 883304
Fax. +44 (0)1634 880066/77
E-mail s.torr@greenwich.ac.uk
Dr Raffaele Mattioli
Animal Health Service, Animal Production and Health Division
Food and Agriculture Organization (FAO)
Viale delle Terme di Caracalla, 00100 Rome, Italy
Tel: (+39) 06 57056078
Fax: (+39) 06 57055749
email: raffaele.mattioli@
Internet:
-----------------------
Subject classification
Fig. 1 : Environmental driving forces on tsetse distribution (West Arica gradient)
Fig. 2: Changing land-use patterns and their effect on the tsetse populationsKd
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d
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Fig. 3: Changes in the epidemiology of bovine trypanosomosis in Southern Africa
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