USAHA/AAVLD Committee on Food and Feed Safety



USAHA/AAVLD Committee on Food and Feed SafetyChair: Tam Garland, TXVice Chair: John Sanders, WVChris Ashworth, AR; James Averill, MI; Deanna Baldwin, MD; Erin Beasley, NC; Richard Benton, MS; Karyn Bischoff, NY; Richard Breitmeyer, CA; Beverly Byrum, OH; Tarrie Crnic, KS; Ignacio dela Cruz, MP; Dubraska Diaz-Campos, WA; Cheryl Eia, MN; Kathy Finnerty, NY; Charles Fossler, CO; Heather Fowler, IA; Tam Garland, TX; Robert Gerlach, AK; Laura Goodman, NY; Jerry Heidel, OR; Susanne Hinkley, NE; Christine Hoang, IL; Donald Hoenig, ME; John Huntley, AZ; Andrea Jackson, DE; Jarra Jagne, NY; Sandra James-Yi, IL; Ghazala Jawad, NC; Annette Jones, CA; Ellen Kasari, CO; Susan Keller, ND; Donna Kelly, PA; Hailu Kinde, CA; Todd Landt, IA; T.R. Lansford, TX; Dale Lauer, MN; Elizabeth Lautner, IA; Laurent Lollis, FL; Karen Lopez, DE; Bret Marsh, IN; David Marshall, NC; Patrick McDonough, NY; Katherine McNamara, VT; David Meeker, VA; Shelley Mehlenbacher, VT; Nicole Neeser, MN; Megin Nichols, GA; Sandra Norman, IN; Kenneth Olson, IL; Stephanie Ostrowski, AL; Lanny Pace, MS; Elizabeth Parker, TX; Amar Patil, NJ; David Pyburn, IA; John Ragan, VA; Shelley Rankin, PA; Renate Reimschuessel, MD; Grant Rezabek, OK; Orhan Sahin, IA; John Sanders, WV; Joni Scheftel, MN; David Schmitt, IA; Richard Sibbel, IA; Kathryn Simmons, DC; Harry Snelson, NC; Anil Thachil, NY; Shauna Voss, MN; Liz Wagstrom, DC; Doug Waltman, GA; Patricia White, CA; Robert Wills, MS; Ross Wilson, TX; Nora Wineland, MO; Raquel Wong, HI. The Committee met on October 21, 2018 at the Sheraton Hotel Crown Center in Kansas City, Missouri from 1:30 to 5:30 p.m. There were 19 members and 21 guests present. At the beginning of the meeting, Dr. Sanders welcomed any members, guests, and students that were attendance for the meeting and encouraged them to participate in the discussions during the afternoon; he briefly reviewed the afternoon’s agenda and reviewed the mission statement of the Food and Feed Safety CommitteePresentations & Reports Vet-LIRN Update: Recent recalls and the 2018 Vet-LIRN’s projectsRenate Reimschuessel, DHHS-FDA-CVM-OFVM-CVM-OR, and the Vet-LIRN.FDAs Center for Veterinary Medicine’s Veterinary Laboratory Investigation and Response Network (Vet-LIRN) has grown from an idea in August 2010 to a functioning network comprising 44 laboratories. The activities initiated during this time are varied yet all focused on forwarding CVM’s mission to promote human and animal health. Proficiency tests: In 2012, Vet-LIRN initiated a proficiency testing (PT) program in collaboration with the Moffett Center and Iowa State University. We conduct, on average, three proficiency tests or inter laboratory exercises per year: chemical, microbiological, or pathology. During 2018 the PT’s were: 1) Campylobacter in feces PT, 2) inter-laboratory comparison (ICE) of anticoagulant rodenticides in liver and 3) Vitamin E in liver (ICE). Funding: Vet-LIRN provides infrastructure funding for Vet-LIRN laboratory activities including conducting investigations, training, travel, and pilot surveillance studies. Currently, 38 laboratories receive funding. In 2013, Vet-LIRN funded five-year Cooperative Agreement program to develop and validate methods in our network. . The program funded 11 projects. A new RFA to evaluate feed-irradiation markers was developed and funded in 2016 2018, Vet-LIRN initiated a new funding opportunity to enhance laboratory capacity via equipment or small project grants, with 30 awards being made in the first year . Cases: Vet-LIRN conducts approximately 30-50 in depth case investigations per year. These cases evaluate consumer reports of potential problems with animal feed or animal drugs. Recent high-profile cases include thyrotoxicosis due to exogenous thyroid in pet food, bacterial pathogens in raw pet foods, and canine dilative cardiomyopathy potentially related to diets.Antimicrobial Resistance: Vet-LIRN was named, along with National Animal Health Laboratory Network (NAHLN), as a partner in the AMR initiative Combating Antibiotic Resistant Bacteria. In 2017, Vet-LIRN initiated a pilot study to test antibiotic susceptibility of selected veterinary pathogens and conduct whole genome sequencing on a subset of these isolates. This project continued in 2018Outreach: Vet-LIRN continues outreach to current and future veterinary and public health professionals. In 2018, Vet-LIRN published an article in Journal of the American Veterinary Medical Association (JAVMA) to describe the case investigation process, gave a public health webinar at HHS, visited two veterinary schools to speak with veterinary students and gave updates at three conferences.Vet-LIRN plans to approach any new tasks needed by CVM with the same energy and innovation that brought the program to its present state.Review of Findings, Recalls and Other Actions Related to Raw Pet Food Done by FDADavid Rotstein, Center of Veterinary Medicine (CVM)Dr. Rotstein reported on recalls that occurred from 2007 to 2018; he described and discussed the classification system for Food and Drug Administration (FDA) recalls and market withdrawals and provided a table with number of events for each year. Two Notable Multistate Foodborne Outbreaks in 2018Matthew Wise, Centers for Disease Control and Prevention (CDC)Dr. Wise described the outbreak with Shiga Toxin-Producing E. coli Infections associated with romaine lettuce and an outbreak of Salmonella Reading Infections associated with turkey products. He noted several issues related to investigating these outbreaks both challenges and successes. The final points of the presentation were these two outbreaks are typical of the outbreaks that CDC has seen this year. Many have involved questions relating to the interface between animal and human health. The Reading outbreak: Is there a single reservoir in the turkey production pyramid or is this a strain that is commonly found across the industry? For the romaine outbreak, to what extent could nearby animal populations play in contamination of irrigation water? We need to collaborate across human and animal health to better understand the root cause of foodborne outbreaks.Investigations of Multistate Enteric Illness Outbreaks Linked to Pet FoodsMegin Nichols, Centers for Disease Control and Prevention (CDC). Dr. Nichols described the steps in a pet food outbreak investigation the one health approach investigation including local, and state health departments; State Agricultural Departments, Health and Human Services (HHS), and USDA. Pets can be asymptotic carriers of campylobacter. Other organization have been associated with pet food. There have been 33 recalls or withdrawals; 18 18 (55%) were raw pet food. Five products had more than pathogen isolated. To assist the public, CDC has created an infographic to educate them on safe pet food handling techniques which can be found at . Additional information about one of the associated pet food outbreaks can be found at . coli O157:H7 Outbreak Linked to Romaine LettuceStic Harris, Food and Drug Administration (FDA) Dr. Harris provide an overview of The Coordinated Outbreak Response and Evaluation network (CORE) is a set of teams responsible for managing surveillance, response, and post response activities related to incidents of illness linked to FDA-regulated human food, cosmetics, and dietary supplements. Working in conjunction with others at FDA, the CDC, and the States, CORE works to identify clusters of illness, trace them back to the source of contamination, and ensure regulatory action to eliminate the public health threat.The 2018 outbreak of E. coli in romaine lettuce from the Yuma growing region has been challenging in identifying the source, scope, and route of contamination. With traceback indicating dozens of farms and several areas of contamination, an environmental assessment (EA) was initiated by CORE with assistance from CDC, the FDA Produce Safety Network, FDA’s Office of Regulatory Affairs, and the Arizona Department of Agriculture. Of the many samples taken during the investigation, three positive samples matching the outbreak strain were identified in canal water used during growth of contaminated lettuce. The resulting EA will be published in its entirety shortly.FSIS Foodborne Illness InvestigationsSheryl Shaw, USDA, Food Safety and Inspection Service (FSIS) Dr. Shaw discussed and described the policies, procedures, information sharing and methods that FSIS uses to investigate foodborne outbreaks associated with products that FSIS regulates. Shaw also described the different measures FSIS can take to protect the health of consumers during the mittee Business:At the conclusion of the scientific presentation, started the business meeting portion of the meeting. Dr. Sanders reminded the committee members to review the mission statement. There were no new business items or resolutions.Lastly before adjourning the meeting at 4:50 p.m., Dr. Sanders brought an idea to the membership to have teleconferences at some interval during the year to keep everyone engaged and more active in conducting the activities of the Committee and to meet the mission of the Committee.Vet-LIRN Update: Recent recalls and the 2018 Vet-LIRN’s projectsRenate Reimschuessel, DHHS-FDA-CVM-OFVM-CVM-OR, and the Vet-LIRN.FDAs Center for Veterinary Medicine’s Veterinary Laboratory Investigation and Response Network (Vet-LIRN) has grown from an idea in August 2010 to a functioning network comprising 44 laboratories. The activities initiated during this time are varied yet all focused on forwarding CVM’s mission to promote human and animal health. Proficiency tests: In 2012, Vet-LIRN initiated a proficiency testing (PT) program in collaboration with the Moffett Center and Iowa State University. We conduct, on average, three proficiency tests or inter laboratory exercises per year: chemical, microbiological, or pathology. During 2018 the PT’s were: 1) Campylobacter in feces PT, 2) inter-laboratory comparison (ICE) of anticoagulant rodenticides in liver and 3) Vitamin E in liver (ICE). Funding: Vet-LIRN provides infrastructure funding for Vet-LIRN laboratory activities including conducting investigations, training, travel, and pilot surveillance studies. Currently, 38 laboratories receive funding. In 2013, Vet-LIRN funded five-year Cooperative Agreement program to develop and validate methods in our network. . The program funded 11 projects. A new RFA to evaluate feed-irradiation markers was developed and funded in 2016 2018, Vet-LIRN initiated a new funding opportunity to enhance laboratory capacity via equipment or small project grants, with 30 awards being made in the first year . Cases: Vet-LIRN conducts approximately 30-50 in depth case investigations per year. These cases evaluate consumer reports of potential problems with animal feed or animal drugs. Recent high-profile cases include thyrotoxicosis due to exogenous thyroid in pet food, bacterial pathogens in raw pet foods, and canine dilative cardiomyopathy potentially related to diets.Antimicrobial Resistance: Vet-LIRN was named, along with National Animal Health Laboratory Network (NAHLN), as a partner in the AMR initiative Combating Antibiotic Resistant Bacteria. In 2017, Vet-LIRN initiated a pilot study to test antibiotic susceptibility of selected veterinary pathogens and conduct whole genome sequencing on a subset of these isolates. This project continued in 2018Outreach: Vet-LIRN continues outreach to current and future veterinary and public health professionals. In 2018, Vet-LIRN published an article in Journal of the American Veterinary Medical Association (JAVMA) to describe the case investigation process, gave a public health webinar at HHS, visited two veterinary schools to speak with veterinary students and gave updates at three conferences.Vet-LIRN plans to approach any new tasks needed by CVM with the same energy and innovation that brought the program to its present state. ................
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