UKMi Q&A xx - SPS
After discontinuing a fentanyl patch, fentanyl levels fall gradually. It takes 17 hours or more for the plasma-fentanyl concentration to decrease by 50% (4-8,11-14). Patients who experience serious adverse effects should have patches removed immediately and should be monitored for at least 24 hours after the patch is removed (4-8,13). ................
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