ICU SEDATION GUIDELINES
Remifentanil, a derivative of fentanyl, is an ultra-short-acting ยต-opioid receptor agonist with a rapid onset of action (~1 minute) and peak effect, and a rapid offset of action following discontinuation of infusion (~3-10 minutes). ... If sedation is not adequate at an infusion rate of 0.2 mcg/kg/min, initiation of an appropriate sedative ... ................
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