11/11/08 - Weebly
The first steps are identical to the synthesis of a conventional glycoprotein: Translation of core protein on membrane-bound ribosomes. Translocation into the lumen of the endoplasmic reticulum. Removal of signal sequence. The carbohydrate chains are formed by O-glycosylation: Sugars are added one at a time from UDP-sugars to elongate the chains. ................
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