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Side effects are not as common in the second-generation antihistamine class when compared to the first-generation antihistamines. Only cetirizine causes sedation at a higher rate than placebo (4). Table : Oral Antihistamines. ... (Flonase) Adults: 1-2 sprays in each nostril once a day or one spray twice a day. Children 4-11-years-old: Start ... ................
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