ALLOPURINOL SODIUM (Zyloprim) NSC #1390

At 1.6-2.4g/m²/d, 12 to 18% of the dose was excreted in the urine, whereas at 5g/m² single-dose, 61% was excreted in the urine. Evidence also exists to suggest that metabolism is inducible, with more rapid clearance occurring in the second and later doses of fractionated courses of 3-5 times daily. ................
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