The Frank–Starling Law: a jigsaw of titin proportions

heart fibers and its power of contraction, the so-called Frank – Starling Law of the Heart (Sequeira and van der Velden 2015). This relationship enables beat-to-beat adjustment of cardiac output in response to changes in venous pressure. At the single cardiac cell level, the Law mandates that there is a direct rela- ................
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